Obesity Fatty Liver And Liver Cancer PDF Download
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Author | : Jun Yu |
Publisher | : Springer |
Total Pages | : 157 |
Release | : 2018-06-28 |
Genre | : Science |
ISBN | : 9811086842 |
Download Obesity, Fatty Liver and Liver Cancer Book in PDF, ePub and Kindle
This volume covers a state-of-the-art illustration of recent discoveries concerning obesity-related fatty liver diseases and liver cancer. The contents are extensive and comprehensive. It brings important topics in the field all together under one umbrella, from epidemiology and etiology, molecular pathogenesis, cellular biology, epigenetics, immunology, microbiology, animal models to therapeutic approaches and treatments. All the book contributors are leading experts in the field. It will appeal to researchers, clinicians and graduate students in obesity, fatty liver diseases, GI/Liver cancer field. It may also yield benefits for pharmaceutical companies with regard to drug discovery.
Author | : Amiya P. Sinha-Hikim |
Publisher | : Frontiers Media SA |
Total Pages | : 95 |
Release | : 2018-04-20 |
Genre | : |
ISBN | : 2889454738 |
Download Obesity, Smoking, and Fatty Liver Disease Book in PDF, ePub and Kindle
The World Health Organization Organization estimates that over 1.9 billion people worldwide are now obese or overweight [body mass index (BMI) > 27 Kg/m2]. Type 2 diabetes (T2D) is now recognized as the most devastating complications of obesity. Intimate relationship exists between obesity, innate (neutrophils, dendritic cells, macrophages, mast cells, and eosinophils) and adaptive (B and T lymphocytes) immune cells. Cells of the innate immune system produce inflammatory cytokines, and other factors leading to impaired insulin secretion and insulin resistance. Likewise, B lymphocytes (mostly B2 cells) are activated in obese adipose tissue and contribute to proinflammatory activation of adipose tissue macrophages and T cells resulting in insulin resistance. Thus, obesity-induced low-grade inflammation in adipose tissue, liver, skeletal muscle, and pancreas not only activates the innate and adaptive systems affecting metabolic homeostasis, it also results in fibrosis and necrosis. It is now becoming increasingly evident that fibrosis is a major contributor to metabolic dysregulation in obese and T2D patients and that advanced liver fibrosis leads to cirrhosis and death. The health risks associated with obesity are further exaggerated by smoking. This research topic consisting of 10 articles (9 reviews and one original) provide a comprehensive assessment of the impact of obesity on immunometabolism, cardiac functions, the connections of nicotine to NAFLD, the expression of hepatic carcinoembryonic antigen related cell adhesion molecule 1 (CEACAM1), the role chromogranin A (CgA) and its peptides pancreastatin (PST) and catestatin (CST) in insulin sensitivity, the loss of skeletal muscle mass and function, and the alternate RNA splicing.
Author | : Jean Baker |
Publisher | : Charles Jesuseyitan Adebola |
Total Pages | : 149 |
Release | : 2018-02-11 |
Genre | : Health & Fitness |
ISBN | : 8832535068 |
Download Fatty Liver Book in PDF, ePub and Kindle
Fatty liver, if not corrected, is often a set off for various diseases and conditions such as: diabetes, inflammation (steatohepatitis), heart diseases, liver cancer (hepatocellular carcinoma), liver scarring (cirrhosis), obesity and untimely death. Fatty liver is the leading cause of liver failure and 3/4 of American adults are affected by fatty liver disease without knowing it. Your liver's health and wellbeing is very important to several other organs in your body; consequently it becomes equally important to take adequate care of the liver and reverse fatty liver disease. This book proffers easy and effective solutions to correct and reverse fatty liver by eating right and making few other lifestyle changes. In this book you will discover how to prevent and reverse fatty liver disease, reduce inflammation, increase energy, control your weight, detoxify the blood and improve your immune function. You will find 80 effective and delicious homemade recipes that will prevent and reverse fatty liver and promote the overall health of your liver.
Author | : Paul J. Gaglio |
Publisher | : Elsevier Health Sciences |
Total Pages | : 195 |
Release | : 2016-08-09 |
Genre | : Medical |
ISBN | : 0323416977 |
Download Non-Alcoholic Fatty Liver Disease, An Issue of Clinics in Liver Disease Book in PDF, ePub and Kindle
Due to the current obesity epidemic, non-alcoholic fatty liver disease (NAFLD) is prevalent in a significant portion of the United States patient population. It is being increasingly recognized that NAFLD affects both adults and children and can progress to end stage liver disease with resultant cirrhosis, portal hypertension, and hepatocellular carcinoma. In addition, several extrahepatic conditions may be linked to NAFLD including cardiovascular disease, insulin requiring and type 2 diabetes mellitus, obstructive sleep apnea, colonic adenomas, hyperuricemia, vitamin D deficiency, hyperferritinemia, pancreatic steatosis, hypothyroidism, and polycystic ovarian syndrome. Therapies for NAFLD are evolving rapidly. This issue will analyze patient demographics, risk factors, pathophysiology, patient presentation, and treatments for NAFLD.
Author | : Zobair Younossi |
Publisher | : Elsevier Health Sciences |
Total Pages | : 297 |
Release | : 2014-02-28 |
Genre | : Medical |
ISBN | : 0323266657 |
Download The Impact of Obesity and Nutrition on Chronic Liver Diseases, An Issue of Clinics in Liver Disease Book in PDF, ePub and Kindle
Internationally renowned experts present topics related to obesity, nutrition, and liver disease in this issue. In the first article, the epidemiology of obesity and its association with liver disease are covered. The following two articles focus on the roles that visceral adipose tissue and microbiota potentially play in the pathogenesis of obesity-related liver disease. The next article focuses on the hepatic pathology seen in patients with obesity-related liver disease and those with malnutrition. The next five articles are focused on NAFLD and provide in-depth data on the natural history and treatment strategies for patients with NAFLD. The next six articles deal with the impact of obesity on other liver diseases and on special populations including children and liver-transplant recipients. The final article provides the most updated information regarding genomics and genetic targets that may provide better prognostic and diagnostic biomarkers and more personalized treatment targets for patients with NAFLD. Cutting-edge information in this issue will help readers gain better understanding of the natural history and pathogenesis of primary and secondary liver diseases associated with obesity. As the information about obesity-related liver disease expands, clinicians will be able to provide more targeted therapeutic options for these patients and develop more accurate diagnostic and prognostic biomarkers.
Author | : Geoffrey C. Farrell |
Publisher | : John Wiley & Sons |
Total Pages | : 438 |
Release | : 2013-02-06 |
Genre | : Medical |
ISBN | : 1118556224 |
Download Non-Alcoholic Fatty Liver Disease Book in PDF, ePub and Kindle
The sharp rise in cases of Non-alcoholic fatty liver disease is fast becoming one of the major concerns for hepatologists worldwide. This comprehensive clinical guide explains how to diagnose NAFLD and manage patients according to the best standards of care. Contributors from the world's leading institutions concentrate on patient care, drawing on their extensive experience.
Author | : Roger Williams |
Publisher | : John Wiley & Sons |
Total Pages | : 256 |
Release | : 2016-02-16 |
Genre | : Medical |
ISBN | : 1118924959 |
Download Clinical Dilemmas in Non-Alcoholic Fatty Liver Disease Book in PDF, ePub and Kindle
Clinical Dilemmas in Non-Alcoholic Fatty Liver Disease offers hepatologists practical, up-to-date and expert guidance on the most topical dilemmas, difficulties and areas of controversy/difficulty surrounding this ever-increasing area of liver disease they face in daily practice. Roger Williams and Simon Taylor-Robinson, two of Europe’s leading hepatologists, have recruited leading figures from across the world to assist them, resulting in a truly international approach. Each chapter covers a specific area of difficulty, containing clear learning points and providing evidence-based expert guidance on the latest hot topics in clinical management such as: Is NAFLD different in absence of Metabolic Syndrome? Are the pros outweighed by the cons of obtaining a liver biopsy? Is progression to cirrhosis more likely in children with NAFLD? What are the dangers as well as the true benefits of bariatric surgery? How is it best to use antifibrotic agents in clinical practice? Clinical Dilemmas in Non-Alcoholic Fatty Liver Disease provides the answers to the questions and challenges that clinicians face every day in this area. It is essential reading for hepatologists of all levels and researchers in hepatology, as well as all those involved in the care of patients with NAFLD, including gastroenterologists, pathologists and specialist hepatology nurses.
Author | : Nicholas J. Talley |
Publisher | : John Wiley & Sons |
Total Pages | : 289 |
Release | : 2008-04-15 |
Genre | : Medical |
ISBN | : 047069145X |
Download GI Epidemiology Book in PDF, ePub and Kindle
Authoritative new text from the experts in GI populationstudies This book covers both key methodological issues and the mostimportant information in the field, disease by disease. It focuseson population-based information and studies looking at principlesand approaches to diagnosis and treatment of diseases. GI Epidemiology brings together world authorities inmultiple disciplines for the very first time, to create one clearand comprehensive source. The bulk of the chapters are divided intotwo parts, covering methodological issues and the epidemiology ofspecific GI diseases. Each chapter begins with a list of keypoints, followed by a review written in a clear and simplestyle. The methodologic chapters cover evidence-based medicine,meta-analysis, systematic reviews, genetic and molecularepidemiology, clinical trials, questionnaire design, and healtheconomics. The disease-specific chapters note the current gaps inknowledge and suggest areas for further study. GI Epidemiology serves as both a useful refresher and areliable reference on the methods and techniques used inepidemiological studies for consultants and researchers ingastroenterology. It is also an invaluable tool for fellows/trainees ingastroenterology, candidates for recertification in the combineddisciplines of gastroenterology, pediatric gastroenterology andcolorectal surgery, and anyone completing MPH training.
Author | : Tatjana Ábel |
Publisher | : Bentham Science Publishers |
Total Pages | : 188 |
Release | : 2017-05-05 |
Genre | : Medical |
ISBN | : 1681084651 |
Download Nonalcoholic Fatty Liver Disease (NAFLD) Book in PDF, ePub and Kindle
Non-alcoholic fatty liver disease (NAFLD) is a common cause of elevated liver enzymes and chronic liver disease in Western countries. NAFLD is characterized by elevated liver enzymes in the absence of alcohol consumption and secondary causes of liver disease. It is an independent predictor of future risk of cardiovascular diseases, type 2 diabetes and metabolic syndrome (hypertension, abdominal obesity, dyslipidemia, glucose intolerance). This book is a quick reference guide for medical students and professionals about NAFLD. Readers will find a summary of epidemiology, clinical features, diagnosis, imaging techniques, histopathology, and disease management. The book also presents information about NAFLD linked with hepatocellular carcinoma and guidelines for treating NAFLD in pediatric patients. Each chapter presents information in a simple, structured manner making this text an ideal handbook for supplementing hepatology modules in medical curricula.
Author | : Naga Chalasani |
Publisher | : Springer |
Total Pages | : 378 |
Release | : 2015-12-10 |
Genre | : Medical |
ISBN | : 3319205382 |
Download Alcoholic and Non-Alcoholic Fatty Liver Disease Book in PDF, ePub and Kindle
This volume is the first text to concisely yet comprehensively cover developments for both alcoholic and nonalcoholic fatty liver disease in an organized fashion. Aspects of these two diseases covered in the book include global epidemiology and risk factors, pathogenesis, animal models, hepatic and extra-hepatic malignancies, treatment models, and current and emerging therapies. Written by experts in the field, Alcoholic and Non-Alcoholic Fatty Liver Disease: Bench to Bedside is a valuable resource for gastroenterologists, pathologists, and hepatologists who treat patients with alcoholic and nonalcoholic fatty liver disease.