Novel Therapeutic Targets For Antiarrhythmic Drugs PDF Download
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| Author | : George Edward Billman |
| Publisher | : John Wiley & Sons |
| Total Pages | : 608 |
| Release | : 2010-01-05 |
| Genre | : Medical |
| ISBN | : 9780470561409 |
Download Novel Therapeutic Targets for Antiarrhythmic Drugs Book in PDF, ePub and Kindle
Profiles potential treatment approaches for cardiac arrhythmias Cardiac arrhythmias of ventricular origin are responsible for the deaths of nearly half a million Americans each year while atrial fibrillation accounts for about 2.3 million cases per year, a rate that is projected to increase 2.5 fold over the next half century. Effectively managing these cardiac rhythm disorders remains a major challenge for both caregivers and the pharmaceutical industry. Filling a gap in the current literature, Novel Therapeutic Targets for Antiarrhythmic Drugs presents the latest treatments for cardiac arrhythmias alongside comprehensive presentations of basic cardiac physiology and pharmacology. Written by leading experts in their research areas, this invaluable resource offers both practitioners and researchers a one-stop guide that brings together previously dispersed information. The text consists of four sections: Section One comprehensively reviews basic cardiac electrophysiology, the mechanisms responsible for arrhythmias in the setting of ischemia, and basic pharmacology of antiarrhythmic drugs. Section Two addresses safety pharmacology, including the concept of "repolarization reserve," safety challenges, and regulatory issues for the development of novel antiarrhythmic drugs. Section Three describes several novel pharmacological targets for antiarrhythmic drugs, including both ion channel and non-ion channel targets. Section Four describes promising non-pharmacological antiarrhythmic interventions including selective cardiac neural disruption or nerve stimulation, aerobic exercise training, and diet (omega-3 fatty acids). Offering an unparalleled look at the current state and future direction of cardiac arrhythmia treatment, Novel Therapeutic Targets for Antiarrhythmic Drugs provides an important resource to advanced students, working researchers, and busy professionals alike.
| Author | : Constantine Mavroudis |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1124 |
| Release | : 2023-01-19 |
| Genre | : Medical |
| ISBN | : 1119282306 |
Download Pediatric Cardiac Surgery Book in PDF, ePub and Kindle
Der Bereich der pädiatrischen Herz- und Gefäßchirurgie umfasst nicht nur die Herzchirurgie bei Säuglingen und Kindern, sondern auch die Herzchirurgie bei Erwachsenen zur Korrektur von angeborenen Herzfehlern. Da die Kindersterblichkeit aufgrund von Herzfehlern zurückgeht und Patienten mit angeborenen Herzfehlern zunehmend ein langes, gesundes Leben führen, ergeben sich neue Herausforderungen. Somit war der Bedarf an Einführungen in diesen lebensrettenden Bereich noch nie so groß. Pediatric Cardiac Surgery ist ein gut verständliches, umfassendes Lehrbuch, das diesen Bedarf seit über dreißig Jahren erfüllt und von Fachleuten auf allen Ebenen genutzt wird. Das Lehrwerk, das zahlreiche farbige Abbildungen enthält, bietet zunächst eine wissenschaftliche Einführung in die kardiovaskuläre Entwicklung und dann detaillierte Analysen von Defekten in verschiedenen Bereichen des Herzens mit den entsprechenden Verfahren zur Korrektur dieser Defekte. Die aktualisierte fünfte Auflage berücksichtigt die neuesten wissenschaftlichen Erkenntnisse und bleibt damit ein unverzichtbares Werk zu diesem Thema. Die fünfte Auflage von Pediatric Cardiac Surgery enthält unter anderem: * Beiträge von über 75 nationalen und internationalen Experten auf dem Gebiet * Beeindruckende anatomische Illustrationen von Rachid Idriss * Neue Kapitel, in denen der neueste Stand der Forschung dargestellt wird, sowie neue Inhalte in Bezug auf die kardiale Bildgebung und die medizinische Ausbildung Pediactric Cardiac Surgery ist ein wichtiges Nachschlagewerk für Herzchirurgen, die sich auf Kinder und Erwachsene spezialisiert haben, Kardiologen und alle medizinischen Fachkräfte, die mit pädiatrischen oder erwachsenen Herzpatienten arbeiten.
| Author | : Ruben Vardanyan |
| Publisher | : Academic Press |
| Total Pages | : 870 |
| Release | : 2016-01-07 |
| Genre | : Medical |
| ISBN | : 0124115241 |
Download Synthesis of Best-Seller Drugs Book in PDF, ePub and Kindle
Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation
| Author | : Alex S. Evers |
| Publisher | : Cambridge University Press |
| Total Pages | : 2902 |
| Release | : 2011-03-10 |
| Genre | : Medical |
| ISBN | : 1139497022 |
Download Anesthetic Pharmacology Book in PDF, ePub and Kindle
In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.
| Author | : Antoni Martínez-Rubio |
| Publisher | : Springer Nature |
| Total Pages | : 433 |
| Release | : 2020-02-03 |
| Genre | : Medical |
| ISBN | : 3030348938 |
Download Antiarrhythmic Drugs Book in PDF, ePub and Kindle
This volume reviews current and potential future therapies for arrhythmias. It is a highly practical guide for the use of pharmaceuticals in the management of the discipline, and has been written in a simple quick-access format. Antiarrhythmic Drugs builds on the current understanding of pathophysiological mechanisms and insights gained from previous studies of therapeutic interventions. It is designed to establish the baseline level of knowledge that a cardiovascular professional needs to know on a day-to-day basis.
| Author | : Cate Whittlesea |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 1112 |
| Release | : 2018-09-11 |
| Genre | : Medical |
| ISBN | : 0702070106 |
Download Clinical Pharmacy and Therapeutics E-Book Book in PDF, ePub and Kindle
‘This new edition of Clinical Pharmacy and Therapeutics was really very helpful when I was doing an MSc course in Advancing Pharmacy Practice and it was really very helpful in all the clinical diseases I have to read for my PBL. I also used it as one of my most reliable reference books for the in-course simulation ward rounds and other clinical case studies. It is a great book to have as a practising clinical or hospital pharmacist or even community pharmacist. It will also be of great use to anyone doing a course in pharmacotherapy. This book will always be of use to you throughout your studentship or when practising after graduation. It is also more portable than most other pharmacotherapy textbooks with the same amount of information.’ Now in its sixth edition, this best-selling, multi-disciplinary textbook continues to draw on the skills of pharmacists, clinicians and nurses to present optimal drug regimens. The authors integrate an understanding of the disease processes with an appreciation of the pathophysiological processes, clinical pharmacy and the evidence base. Each chapter is co-written by a pharmacist and a clinician, and each chapter begins with key points and ends with cases to test understanding. The sixth edition is now on StudentConsult for the first time, giving online access to the full text. Key points boxes at the beginning of each chapter Case-study boxes throughout the chapters Each chapter co-written by a pharmacist and a clinician In-depth treatment of therapeutics to support pharmaceutical prescribing Logical order and format: key points, epidemiology, aetiology, disease, clinical manifestations, investigations and treatment, drugs used in treatment. Dosage reference sources given where appropriate, along with useful websites and further reading for each chapter. New co-editor, Karen Hodson Over 10 new authors Now in 4-colour On StudentConsult for the first time New chapter on Dementia Many new and revised illustrations Chapters revised to include advances in therapeutics and changes to dose regimens and licensed indications Updated case studies
| Author | : Roger Walker |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 998 |
| Release | : 2011-10-24 |
| Genre | : Medical |
| ISBN | : 0702048488 |
Download Clinical Pharmacy and Therapeutics E-Book Book in PDF, ePub and Kindle
Now in its fifth edition, this best-selling, multidisciplinary textbook continues to draw on the skills of pharmacists and clinicians to present optimal drug regimens. The authors integrate an understanding of the disease processes with an appreciation of pathophysiological processes, clinical pharmacy and the evidence base. New to this edition: Stronger emphasis on understanding both the prescribing process and the clinical pharmacy process. All chapters completely revised and updated. Thirty-eight leading new authors. Features: Key points boxes at the beginning of every chapter Case study tests at the end of every chapter Chapters co-authored by pharmacists and clinicians Organised by body system Consistent, clearly signposted chapter layout ‘...a unique and valuable support for all those involved or interested in drug therapy. This is a textbook that no university or pharmacy department, particularly those with employees studying at any level, and no pharmacist trying to develop their knowledge base should be without." Dr Chris Green and John Sexton, The Pharmaceutical Journal Now in its fifth edition, this best-selling, multidisciplinary textbook continues to draw on the skills of pharmacists and clinicians to present optimal drug regimens. The authors integrate an understanding of the disease processes with an appreciation of pathophysiological processes, clinical pharmacy and the evidence base. New to this edition: Stronger emphasis on understanding both the prescribing process and the clinical pharmacy process. All chapters completely revised and updated. Thirty-eight leading new authors. Features: Key points boxes at the beginning of every chapter Case study tests at the end of every chapter Chapters co-authored by pharmacists and clinicians Organised by body system Consistent, clearly signposted chapter layout ‘...a unique and valuable support for all those involved or interested in drug therapy. This is a textbook that no university or pharmacy department, particularly those with employees studying at any level, and no pharmacist trying to develop their knowledge base should be without." Dr Chris Green and John Sexton, The Pharmaceutical Journal Stronger emphasis on understanding both the prescribing process and the clinical pharmacy process. All chapters completely revised and updated. Thirty-eight leading new authors.
| Author | : Eelco F. M. Wijdicks |
| Publisher | : Oxford University Press |
| Total Pages | : 353 |
| Release | : 2018 |
| Genre | : Medical |
| ISBN | : 0190684747 |
Download Neurocritical Care Pharmacotherapy Book in PDF, ePub and Kindle
Neurocritical Care Pharmacotherapy: A Clinican's Guide is a practical, succinct but comprehensive pharmacy handbook provides up-to-date clinical guidance on the effective selection, prescription, and usage of neurocritical care drugs for patients with acute neurologic illnesses. The treatment of the critically ill neurologic patient is often difficult, specialized, and includes drugs infrequently used in other intensive care units such as antiepileptic drugs, osmotic agents or acute immunotherapy such as intravenous immunoglobulin and plasma exchange. This text discusses choosing the right combination of drugs; how to correctly prescribe and administer the drugs; how to monitor drug efficacy and side effects; how neurocritical care drugs interact with other medications; and comprehensive coverage of current treatment options. Key Feature of this Manual Include - A brief discussion of the basic pharmacology of each neurocritical drug, with an emphasis on how to select and use these drugs in multiple clinical contexts. - 150 drugs accompanied by a diagram for quick comprehension and drug administration guides. - Unique blending of expertise of neurointensivist with a critical care pharmacist to provide a vital resource for both specialities - References for further reading that are oriented toward utility in clinical practice.
| Author | : Ihor Gussak |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 600 |
| Release | : 2008-09-08 |
| Genre | : Medical |
| ISBN | : 1846288541 |
Download Electrical Diseases of the Heart Book in PDF, ePub and Kindle
This book provides a unique contemporary and succinct distillation of the current status of recently delineated electrical diseases of the heart, emphasizing their common and diverse clinical features. The latest developments in the field of experimental and clinical cardiac electrophysiology, genetics, pharmacology and interventional therapies of various clinical arrhythmogenic entities are featured and discussed in terms of recent advances in basic and clinical science. The book is divided into seven major parts. Each part consists of chapters (total of 64) dealing with related topics.
| Author | : James L. Marcum |
| Publisher | : Tyndale House Publishers, Inc. |
| Total Pages | : 258 |
| Release | : 2013-01-17 |
| Genre | : Religion |
| ISBN | : 1414382804 |
Download Medicines That Kill Book in PDF, ePub and Kindle
The recent deaths of celebrities like Michael Jackson, Anna Nicole Smith, Heath Ledger, and Whitney Houston have shown a spotlight on the overuse and abuse of prescription drugs. Most people believe that prescription drugs are safer than illegal substances. But, when combined with other over-the-counter sedatives, prescription drugs can be every bit as powerful, addictive, and dangerous. In 2006, overdoses on a class of prescription pain relievers called opioid analgesics killed more people than those killed by overdoses on cocaine and heroin combined. Right now, among 35 to 54 year olds, poisoning by prescription drugs is the most common cause of accidental death—even more so than auto-related deaths. In Medicines That Kill, Dr. Marcum shines a light on the addictive power of prescription medication and how you can protect yourself and your family by practicing healthy habits.
