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| Author | : |
| Publisher | : Frontiers Media SA |
| Total Pages | : 152 |
| Release | : 2022-11-04 |
| Genre | : Science |
| ISBN | : 2832504000 |
| Author | : Derick Han |
| Publisher | : CRC Press |
| Total Pages | : 522 |
| Release | : 2015-10-28 |
| Genre | : Medical |
| ISBN | : 1482236982 |
" excellent, well-organized, and timely."-Lester Packer and Enrique Cardenas, University of Southern California, Los Angeles, from the Series PrefaceThe liver is a vital organ that is responsible for a wide range of functions, most of which are essential for survival. The multitude of functions the liver performs makes it vulnerable to a wide range
| Author | : George E. Barreto |
| Publisher | : Springer Nature |
| Total Pages | : 603 |
| Release | : 2021-04-16 |
| Genre | : Medical |
| ISBN | : 3030648729 |
Medicinal plants and their derived products remain as an indispensable source of bioactive molecules that serve as either drug candidates or lead compounds for drug design and discovery. There are several advantages for plant-derived therapeutics including wide availability, diverse pharmacological actions and a generally good profile of safety and tolerability. Over the recent years, there have been numerous reports from clinical studies testifying to the efficacy and safety of medicinal plants and phytochemicals in ameliorating several human diseases. A plethora of basic studies has also unravelled molecular mechanisms underlying the health benefits of herbal medicines. Nevertheless, issues such as identification of bioactive ingredients, standardization of the products and drug interactions remain to be further studied. In this book, we aim to put together several chapters on the medicinal properties and pharmacological action of medicinal plants, plant species and phytochemicals. The goal is to present a comprehensive collection on most of the therapeutic aspects of plant-derived natural products and molecular mechanisms thereof.
| Author | : Sir William Osler |
| Publisher | : New York : D. Appleton |
| Total Pages | : 188 |
| Release | : 1897 |
| Genre | : Angina pectoris |
| ISBN | : |
| Author | : Frederick J. Suchy |
| Publisher | : Cambridge University Press |
| Total Pages | : 875 |
| Release | : 2021-03-18 |
| Genre | : Medical |
| ISBN | : 1108911374 |
Liver disease in children is increasing in prevalence, placing a huge burden on healthcare systems and often requiring long-term management. Offering an integrative approach to the science and clinical practice of pediatric hepatology, this is the definitive reference text for improved diagnosis and treatment strategies. In the new edition of this authoritative text, chapters have been thoroughly revised in line with major advances in the field, such as recognizing the increased frequency of fatty liver disease, and how genetic testing has the potential to establish earlier diagnoses for a variety of diseases. Disorders covered include cholestasis, metabolic disorders and hepatitis, with their presentation across the spectrum of infancy, childhood and adolescence discussed. The indications and surgical aspects of liver transplant are explained and post-transplant care is described in detail. This is a valuable resource for pediatricians, hepatologists, gastroenterologists and all clinicians involved in the care of children with liver diseases.
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 288 |
| Release | : 2019-07-13 |
| Genre | : Medical |
| ISBN | : 0128173173 |
Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series
| Author | : Jun Yu |
| Publisher | : Springer |
| Total Pages | : 157 |
| Release | : 2018-06-28 |
| Genre | : Science |
| ISBN | : 9811086842 |
This volume covers a state-of-the-art illustration of recent discoveries concerning obesity-related fatty liver diseases and liver cancer. The contents are extensive and comprehensive. It brings important topics in the field all together under one umbrella, from epidemiology and etiology, molecular pathogenesis, cellular biology, epigenetics, immunology, microbiology, animal models to therapeutic approaches and treatments. All the book contributors are leading experts in the field. It will appeal to researchers, clinicians and graduate students in obesity, fatty liver diseases, GI/Liver cancer field. It may also yield benefits for pharmaceutical companies with regard to drug discovery.
| Author | : Marilena Idzojtic |
| Publisher | : Academic Press |
| Total Pages | : 800 |
| Release | : 2019-06-28 |
| Genre | : Nature |
| ISBN | : 0128196459 |
Dendrology: Cones, Flowers, Fruits and Seeds offers a comprehensive overview of the morphology of reproductive organs of woody plants of Europe in one resource. The book contains 2020 woody taxa (845 species, 58 subspecies, 38 varieties, 13 forms, 40 hybrids and 1026 cultivars), belonging to 400 genera and 121 families. It includes 447 taxa of trees and shrubs that are autochthonous in Europe and numerous ornamental species that originate from North America, Asia, South America, Australia and Africa, along with invasive woody species. Accompanied by thousands of original photographs, the book is designed to efficiently guide the reader to accurate identification. Other features include taxa organized in alphabetical order of their botanical names, flowering and fruiting time, mode of fruit or seed dispersal, and distribution range, making this a must-have reference for students and researchers in dendrology, botany, forestry, forest management and conservation, arboriculture and horticulture. Includes 2,020 taxa of trees and shrubs important for the European dendrology Provides detailed descriptions of reproductive organs and data on the reproductive biology of the described taxa Contains 6,644 original, high-quality photographs of habits, cones, flowers, fruits and seeds
| Author | : Lorenzo D'Antiga |
| Publisher | : Springer |
| Total Pages | : 829 |
| Release | : 2019-04-29 |
| Genre | : Medical |
| ISBN | : 3319964003 |
This book is the first to provide balanced examination of both pediatric liver disease and liver transplantation – two topics that are inherently related, given that most chronic liver disorders eventually require organ replacement. The different forms of liver disease encountered in the pediatric age group are first discussed in a series of disease-specific chapters that have a reader-friendly, uniform structure covering pathophysiology, diagnostic and treatment algorithms, clinical cases, and transition to adult care. Key topics in the field of liver transplantation are then addressed. Examples include indications and contraindications, surgical techniques and complications, immunosuppression, in pediatric liver transplantation, acute and chronic rejection and allograft dysfunction, and CMV and EBV infection in transplant recipients, long-term graft injury and tolerance. A section on pediatric hepatology across the world includes chapters presenting the features and management of pediatric liver disease in South-America, Africa and Asia. A closing section considers what the future holds for pediatric liver disease and its management, including novel genetic testing, cell therapy and gene therapy. Pediatric Hepatology and Liver Transplantation will be of value for a range of practitioners, from residents making their first approach to pediatric liver disease through to specialists working in transplantation centers.
| Author | : Lawrence H. Lash |
| Publisher | : Elsevier |
| Total Pages | : 527 |
| Release | : 2013-10-22 |
| Genre | : Science |
| ISBN | : 1483218619 |
Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.
