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High-resolution NMR Techniques in Organic Chemistry

High-resolution NMR Techniques in Organic Chemistry
Author: T. Claridge
Publisher: Elsevier
Total Pages: 408
Release: 1999-12-24
Genre: Science
ISBN: 9780080427997

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From the initial observation of proton magnetic resonance in water and in paraffin, the discipline of nuclear magnetic resonance has seen unparalleled growth as an analytical method. Modern NMR spectroscopy is a highly developed, yet still evolving, subject which finds application in chemistry, biology, medicine, materials science and geology. In this book, emphasis is on the more recently developed methods of solution-state NMR applicable to chemical research, which are chosen for their wide applicability and robustness. These have, in many cases, already become established techniques in NMR laboratories, in both academic and industrial establishments. A considerable amount of information and guidance is given on the implementation and execution of the techniques described in this book.


Applications of NMR Spectroscopy

Applications of NMR Spectroscopy
Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
Total Pages: 289
Release: 2016-11-22
Genre: Science
ISBN: 168108287X

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Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture. The fifth volume of the series features several reviews focusing on NMR spectroscopic techniques for identifying natural and synthetic compounds (polymer and peptide characterization, GABA in tinnitus affected mice), medical diagnosis and therapy (gliomas) and food analysis. The spectroscopic methods highlighted in this volume include high resolution proton magnetic resonance spectroscopy and solid state NMR.


NMR Spectroscopy

NMR Spectroscopy
Author: Harald Günther
Publisher: John Wiley & Sons
Total Pages: 842
Release: 2013-12-13
Genre: Science
ISBN: 3527674772

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Nuclear magnetic resonance (NMR) spectroscopy is one of the most powerful and widely used techniques in chemical research for investigating structures and dynamics of molecules. Advanced methods can even be utilized for structure determinations of biopolymers, for example proteins or nucleic acids. NMR is also used in medicine for magnetic resonance imaging (MRI). The method is based on spectral lines of different atomic nuclei that are excited when a strong magnetic field and a radiofrequency transmitter are applied. The method is very sensitive to the features of molecular structure because also the neighboring atoms influence the signals from individual nuclei and this is important for determining the 3D-structure of molecules. This new edition of the popular classic has a clear style and a highly practical, mostly non-mathematical approach. Many examples are taken from organic and organometallic chemistry, making this book an invaluable guide to undergraduate and graduate students of organic chemistry, biochemistry, spectroscopy or physical chemistry, and to researchers using this well-established and extremely important technique. Problems and solutions are included.


Nuclear Magnetic Resonance Spectroscopy

Nuclear Magnetic Resonance Spectroscopy
Author: Joseph B. Lambert
Publisher: John Wiley & Sons
Total Pages: 485
Release: 2019-01-04
Genre: Science
ISBN: 1119295238

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Combines clear and concise discussions of key NMR concepts with succinct and illustrative examples Designed to cover a full course in Nuclear Magnetic Resonance (NMR) Spectroscopy, this text offers complete coverage of classic (one-dimensional) NMR as well as up-to-date coverage of two-dimensional NMR and other modern methods. It contains practical advice, theory, illustrated applications, and classroom-tested problems; looks at such important ideas as relaxation, NOEs, phase cycling, and processing parameters; and provides brief, yet fully comprehensible, examples. It also uniquely lists all of the general parameters for many experiments including mixing times, number of scans, relaxation times, and more. Nuclear Magnetic Resonance Spectroscopy: An Introduction to Principles, Applications, and Experimental Methods, 2nd Edition begins by introducing readers to NMR spectroscopy - an analytical technique used in modern chemistry, biochemistry, and biology that allows identification and characterization of organic, and some inorganic, compounds. It offers chapters covering: Experimental Methods; The Chemical Shift; The Coupling Constant; Further Topics in One-Dimensional NMR Spectroscopy; Two-Dimensional NMR Spectroscopy; Advanced Experimental Methods; and Structural Elucidation. Features classical analysis of chemical shifts and coupling constants for both protons and other nuclei, as well as modern multi‐pulse and multi-dimensional methods Contains experimental procedures and practical advice relative to the execution of NMR experiments Includes a chapter-long, worked-out problem that illustrates the application of nearly all current methods Offers appendices containing the theoretical basis of NMR, including the most modern approach that uses product operators and coherence-level diagrams By offering a balance between volumes aimed at NMR specialists and the structure-determination-only books that focus on synthetic organic chemists, Nuclear Magnetic Resonance Spectroscopy: An Introduction to Principles, Applications, and Experimental Methods, 2nd Edition is an excellent text for students and post-graduate students working in analytical and bio-sciences, as well as scientists who use NMR spectroscopy as a primary tool in their work.


Protein NMR Spectroscopy

Protein NMR Spectroscopy
Author: Lu-Yun Lian
Publisher: John Wiley & Sons
Total Pages: 345
Release: 2011-06-09
Genre: Science
ISBN: 1119972825

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Nuclear Magnetic Resonance (NMR) spectroscopy, a physical phenomenon based upon the magnetic properties of certain atomic nuclei, has found a wide range of applications in life sciences over recent decades. This up-to-date volume covers NMR techniques and their application to proteins, with a focus on practical details. Providing newcomers to NMR with practical guidance to carry out successful experiments with proteins and analyze the resulting spectra, those familiar with the chemical applications of NMR will also find it useful in understanding the special requirements of protein NMR.


In Vivo NMR Spectroscopy

In Vivo NMR Spectroscopy
Author: Robin A. de Graaf
Publisher: John Wiley & Sons
Total Pages: 584
Release: 2019-03-11
Genre: Science
ISBN: 1119382548

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Presents basic concepts, experimental methodology and data acquisition, and processing standards of in vivo NMR spectroscopy This book covers, in detail, the technical and biophysical aspects of in vivo NMR techniques and includes novel developments in the field such as hyperpolarized NMR, dynamic 13C NMR, automated shimming, and parallel acquisitions. Most of the techniques are described from an educational point of view, yet it still retains the practical aspects appreciated by experimental NMR spectroscopists. In addition, each chapter concludes with a number of exercises designed to review, and often extend, the presented NMR principles and techniques. The third edition of In Vivo NMR Spectroscopy: Principles and Techniques has been updated to include experimental detail on the developing area of hyperpolarization; a description of the semi-LASER sequence, which is now a method of choice; updated chemical shift data, including the addition of 31P data; a troubleshooting section on common problems related to shimming, water suppression, and quantification; recent developments in data acquisition and processing standards; and MatLab scripts on the accompanying website for helping readers calculate radiofrequency pulses. Provide an educational explanation and overview of in vivo NMR, while maintaining the practical aspects appreciated by experimental NMR spectroscopists Features more experimental methodology than the previous edition End-of-chapter exercises that help drive home the principles and techniques and offer a more in-depth exploration of quantitative MR equations Designed to be used in conjunction with a teaching course on the subject In Vivo NMR Spectroscopy: Principles and Techniques, 3rd Edition is aimed at all those involved in fundamental and/or diagnostic in vivo NMR, ranging from people working in dedicated in vivo NMR institutes, to radiologists in hospitals, researchers in high-resolution NMR and MRI, and in areas such as neurology, physiology, chemistry, and medical biology.


NMR Spectroscopy Techniques

NMR Spectroscopy Techniques
Author: Martha Bruch
Publisher: CRC Press
Total Pages: 632
Release: 1996-03-05
Genre: Science
ISBN: 1482273314

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This work elucidates the power of modern nuclear magnetic resonance (NMR) techniques to solve a wide range of practical problems that arise in both academic and industrial settings. This edition provides current information regarding the implementation and interpretation of NMR experiments, and contains material on: three- and four-dimensional NMR;


Basic 1H- and 13C-NMR Spectroscopy

Basic 1H- and 13C-NMR Spectroscopy
Author: Metin Balci
Publisher: Elsevier
Total Pages: 441
Release: 2005-01-19
Genre: Science
ISBN: 0080525539

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Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful and theoretically complex analytical tool. Basic 1H- and 13C-NMR Spectroscopy provides an introduction to the principles and applications of NMR spectroscopy. Whilst looking at the problems students encounter when using NMR spectroscopy, the author avoids the complicated mathematics that are applied within the field. Providing a rational description of the NMR phenomenon, this book is easy to read and is suitable for the undergraduate and graduate student in chemistry. Describes the fundamental principles of the pulse NMR experiment and 2D NMR spectra Easy to read and written with the undergraduate and graduate chemistry student in mind Provides a rational description of NMR spectroscopy without complicated mathematics


NMR Spectroscopy Techniques, Second Edition,

NMR Spectroscopy Techniques, Second Edition,
Author: Martha Bruch
Publisher: CRC Press
Total Pages: 634
Release: 1996-03-05
Genre: Science
ISBN: 9780585374901

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This work elucidates the power of modern nuclear magnetic resonance (NMR) techniques to solve a wide range of practical problems that arise in both academic and industrial settings. This edition provides current information regarding the implementation and interpretation of NMR experiments, and contains material on: three- and four-dimensional NMR; the NMR analysis of peptides, proteins, carbohydrates and oligonucleotides; and more.


In Vivo NMR Spectroscopy

In Vivo NMR Spectroscopy
Author: Robin A. de Graaf
Publisher: John Wiley & Sons
Total Pages: 563
Release: 2013-03-21
Genre: Science
ISBN: 1118681304

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This is the second edition of a unique book in the field of in vivo NMR covering in detail the technical and biophysical aspects of the technique. The contents of the book are appropriate to both beginners and experienced users of in vivo NMR spectroscopy. The new edition is focussed on bringing the reader practical insights and advice, but is also geared towards use as a study aid and in NMR courses. Recent advances in NMR spectroscopy, like high field NMR, hyperpolarized NMR and new localization and editing techniques have been included. An extensive and updated treatment of radiofrequency pulses is given, together with several tables and recipes for their generation. Solutions to the exercises within this text can be found here