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| Author | : Louis J. Ignarro |
| Publisher | : Academic Press |
| Total Pages | : 1023 |
| Release | : 2000-09-13 |
| Genre | : Medical |
| ISBN | : 0080525032 |
Download Nitric Oxide Book in PDF, ePub and Kindle
Nitric oxide (NO) is a gas that transmits signals in an organism. Signal transmission by a gas that is produced by one cell and which penetrates through membranes and regulates the function of another cell represents an entirely new principle for signaling in biological systems. NO is a signal molecule of key importance for the cardiovascular system acting as a regulator of blood pressure and as a gatekeeper of blood flow to different organs. NO also exerts a series of other functions, such as acting a signal molecule in the nervous system and as a weapon against infections. NO is present in most living creatures and made by many different types of cells. NO research has led to new treatments for treating heart as well as lung diseases, shock, and impotence. Scientists are currently testing whether NO can be used to stop the growth of cancerous tumors, since the gas can induce programmed cell death, apoptosis. This book is the first comprehensive text on nitric oxide to cover all aspects--basic biology, chemistry, pathobiology, effects on various disease states, and therapeutic implications. Edited by Nobel Laureate Louis J. Ignarro, editor of the Academic Press journal, Nitric Oxide Authored by world experts on nitric oxide Includes an overview of basic principles of biology and chemical biology Covers principles of pathobiology, including the nervous system, cardiovascular function, pulmonary function, and immune defense
| Author | : S. Moncada |
| Publisher | : Princeton University Press |
| Total Pages | : 328 |
| Release | : 2017-03-14 |
| Genre | : Science |
| ISBN | : 1400887534 |
Download Nitric Oxide and the Cell Book in PDF, ePub and Kindle
Nitric oxide has proven to be a molecule with wide biological significance. It is involved in myriad actions which range from physiology to pathophysiology. One of the fundamental questions in relation to its biological relevance concerns the paradoxical nature of some of its actions. For example, there is a whole range of effects related to cytoprotection, cell proliferation, differentiation, and cell death. The way in which nitric oxide becomes involved in pathophysiology is slowly being elucidated. This volume contains a summary of the discussions that took place at the Second International Paraelios Symposium on Nitric Oxide research, and will make a significant contribution to this very exciting subject. Originally published in 1998. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
| Author | : Jeffrey D. Laskin |
| Publisher | : CRC Press |
| Total Pages | : 408 |
| Release | : 1999-02-26 |
| Genre | : Science |
| ISBN | : 9780824719654 |
Download Cellular and Molecular Biology of Nitric Oxide Book in PDF, ePub and Kindle
"Provides the latest advances in the explosive growth of nitric oxide (NO) study-covering the behavior of this highly reactive molecule in a wide variety of physiologicial processes, including respiration, blood pressure, neurotransmission, nospecific host defense, and wound healing."
| Author | : Tamás Rőszer |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 214 |
| Release | : 2012-01-14 |
| Genre | : Medical |
| ISBN | : 9400728190 |
Download The Biology of Subcellular Nitric Oxide Book in PDF, ePub and Kindle
This book fills in a gap in the NO literature. Recent progress in the field of NO-biology shows that NO is generated within distinct cell compartments, including specific plasma membrane regions, mitochondria, chloroplasts, peroxisomes, the Golgi-complex and intracellular membrane systems. NO synthesis plays specific roles in these compartments and, in turn, cell organelles also control intracellular NO levels. This monograph focuses on the roles played by the subcellular NO-signaling microdomains in the prokaryote-, fungus-, plant- and animal cells and shows how NO behaves as an intracellular signal in distinct cellular environments. This monograph also provides a summary of our knowledge on how NO synthesis came through evolution to be associated with organelles and subcellular compartments. Promotes the novel ideas that some functions of NO and its associations with subcellular units have been conserved during the evolution of the cell. A special chapter is dedicated to the biomedical relevance of subcellular NO synthesis, and this chapter also discusses the evidence that altered compartmentalization of NO-producing enzymes causes disease.
| Author | : Louis J. Ignarro |
| Publisher | : Academic Press |
| Total Pages | : 852 |
| Release | : 2009-11-05 |
| Genre | : Science |
| ISBN | : 0080920446 |
Download Nitric Oxide Book in PDF, ePub and Kindle
Nitric oxide (NO) is a gas naturally found in the body that conveys information between cells. In the last decade researchers have found that NO is a signaling molecule of key importance for the cardiovascular system, regulating blood pressure and blood flow to different organs. In addition, discoveries surrounding nitric oxide’s role as a principal neurotransmitter moderating erectile function, a pathophysiological negotiator and messenger in inflammation, and a weapon against infections have increased research attention across the fields of biochemistry, chemistry, molecular biology, gene therapy, cell biology, immunology, pharmacology, neuroscience, and physiology. Edited by Nobel Laureate Louis J. Ignarro Up-to-date therapeutic implications of nitric oxide research Authored by world experts on nitric oxide Detailed research of the biochemistry and synthesis of nitric oxide
| Author | : Santiago Lamas |
| Publisher | : CRC Press |
| Total Pages | : 453 |
| Release | : 2005-11-01 |
| Genre | : Science |
| ISBN | : 1420027166 |
Download Nitric Oxide, Cell Signaling, and Gene Expression Book in PDF, ePub and Kindle
Since the nineteenth century, when engineers were using nitroglycerin to blow up rockbeds, and doctors were prescribing it to relieve angina, scientists have been exploring the incredible and often baffling behavior of nitric oxide. In the 1980s, researchers discovered that nitric oxide had the capacity to regulate vascular tone through cyclic GMP,
| Author | : Daniela Salvemini |
| Publisher | : Springer |
| Total Pages | : 308 |
| Release | : 2013-03-11 |
| Genre | : Medical |
| ISBN | : 3034882416 |
Download Nitric Oxide and Inflammation Book in PDF, ePub and Kindle
Literally thousands of papers have been published on nitric oxide over the past ten years. But there is no single monograph available that has previously attempted to summarize the important features of the roles of nitric oxide in inflammation. The voluminous literature regarding the incredible range of chemical and biological effects of nitric oxide and reactive nitrogen oxide species, RNOS, may present a tangle of confusing information to the researcher. This volume brings together experts from nitric oxide and inflammation research and presents a concise up-to-date overview as well as future aspects of this rapidly growing field.
| Author | : S. Moncada |
| Publisher | : Ashgate Publishing |
| Total Pages | : 305 |
| Release | : 1998-01-01 |
| Genre | : Apoptosis |
| ISBN | : 9781855781207 |
Download Nitric Oxide and the Cell Book in PDF, ePub and Kindle
This volume contains papers covering aspects of nitric oxide and the cell.
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 556 |
| Release | : 1995-11-29 |
| Genre | : Medical |
| ISBN | : 0080581269 |
Download Biochemistry, Molecular Biology, and Therapeutic Implications Book in PDF, ePub and Kindle
Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. This volume contains chapters that address diverse but interrelated areas pertaining to the chemistry, biochemistry, molecular biology, and pharmacology of nitric oxide in mammalian cells. The contents form a comprehensive treatise of factors influencing the control of nitric oxide production in various cell types. Presents comprehensive coverage of the chemical properties of nitric oxide and how they form the basis for the multifaceted biological actions for nitric oxide Contains the most current and detailed documentation of the properties and regulation of nitric oxide synthases Provides the most up-to-date review of inhalational nitric oxide therapy for treatment of respiratory dysfunction
| Author | : Benjamin Bonavida |
| Publisher | : Springer |
| Total Pages | : 319 |
| Release | : 2015-05-12 |
| Genre | : Medical |
| ISBN | : 3319136119 |
Download Nitric Oxide and Cancer: Pathogenesis and Therapy Book in PDF, ePub and Kindle
Advances in Nitric Oxide and Cancer is a volume that serves to give the latest research on nitric oxide (NO) and cancer. More specifically, the volume reviews significant advances in the application of NO-mediated drugs. The volume explores nitric oxide and its relationship to cancer spanning from its roles in the pathogenesis, prognosis, gene and protein modifications, regulation of resistance to cytotoxics, and therapeutic applications. With chapters written by leading experts, the volume addresses the burgeoning interest in a rapidly advancing field and provides a valuable resource to scientists who have initiated research as well as clinical investigations in their laboratories on the various roles of NO and cancer.
