Nitric Oxide And Nitric Oxide Donors PDF Download
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Author | : Peng George Wang |
Publisher | : John Wiley & Sons |
Total Pages | : 407 |
Release | : 2005-08-16 |
Genre | : Science |
ISBN | : 3527603840 |
Download Nitric Oxide Donors Book in PDF, ePub and Kindle
Nitric oxide is a highly potent regulatory molecule with great pharmaceutical potential. This handbook fills a real gap in combining the chemistry of nitric oxide releasing substances with their practical applications in biology and drug design. It covers all classes of nitric oxide donors, from organic nitrates to nitroso compounds, guanidines and metal-NO complexes. In addition to a detailed treatment of the chemistry of NO donors, numerous examples of successful diagnostic and pharmacological applications are discussed, as well as further therapeutic targets for these substances.
Author | : Amedea Seabra |
Publisher | : Academic Press |
Total Pages | : 367 |
Release | : 2017-03-17 |
Genre | : Medical |
ISBN | : 0128134593 |
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Nitric Oxide Donors: Biomedical Applications and Perspectives presents the current state of art, challenges and innovations in the design of therapeutics nitric oxide donors with great impact in several aspects of human physiology and pathophysiology. Although considerable innovative progress has been achieved using Nitric Oxide donors in biomedical applications, certain drawbacks still need to be overcome to successfully translate these research innovations into clinical applications. This book encompasses several topics on nitric oxide such as its sources and biological properties; its performance in the cardiovascular and neurologic systems, in the human skin and its application in the treatment of neglected diseases, neurodegenerative disorders, and cancer. Additionally, it covers its role in inflammation and immunity, penile erection function, photodynamic therapy, antimicrobial activities. It also discusses the future of nitric oxide donors in combination with other therapeutic drugs, in implantable sensors, and nitric oxide releasing hydrogels and medical devices for topical applications. The book is a valuable source for researchers on different areas of biomedical field who are interested in the improvements that these molecules can make in the treatment of several conditions. Provides background information about biology and chemistry of nitric oxide Discusses the state-of-the-art in the design of nitric oxide releasing nanomaterials for biomedical applications Covers the usage of nitric oxide donors in the treatment of several conditions, such as cancer, human skin, cardiovascular system, and immunity Discusses the future of nitric oxide donors and their FDA approval
Author | : Lucia Morbidelli |
Publisher | : Academic Press |
Total Pages | : 372 |
Release | : 2019-02-09 |
Genre | : Medical |
ISBN | : 0128172797 |
Download Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders Book in PDF, ePub and Kindle
Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders presents updated reviews on the chemistry, signaling, pre-clinical and clinical activities on the role of nitric oxide donors/inhibitors used alone and in combination with other therapeutic agents for the treatment of a variety of diseases. This book examines various studies related to the application of novel therapeutic NO (donors/inhibitors) compounds in the treatment of various cancers. These studies have been shown to exert significant therapeutic activities against various cancers and various inflammatory diseases such as rheumatoid arthritis, Crohn’s disease, allergies, and asthma, where no current effective therapies exist. Pathologies based on functional and structural vascular alterations are also taken into consideration. Edited and written by internationally renowned experts in the field of novel therapeutics for cancer, this book is a valuable source for cancer researchers, medical scientists, clinicians, clinical pharmacologists, and graduate students. Provides readers with a clear overview of the recent findings and references as well as summaries, significant molecular pathways, and conclusions Discusses new ideas proposed and makes suggestions for further investigations that will advance the field Presents introductory and summary information on the contributions of the field, all the findings of the studies discussed, and projects future goals for research
Author | : Raúl Bescós García |
Publisher | : |
Total Pages | : |
Release | : 2012 |
Genre | : |
ISBN | : |
Download The Effect of Nitric Oxide Donors on Human Performance Book in PDF, ePub and Kindle
Author | : Chih-Ming Leo Tseng |
Publisher | : |
Total Pages | : 418 |
Release | : 1998 |
Genre | : |
ISBN | : |
Download Mechanisms of Action of Nitric Oxide Donors: a Comparative Study of Nitroglycerin Vs. S-ntroso-n-acetylpenicillamine Book in PDF, ePub and Kindle
Author | : Keith Rome |
Publisher | : Elsevier Health Sciences |
Total Pages | : 271 |
Release | : 2014-09-18 |
Genre | : Medical |
ISBN | : 0702060763 |
Download Management of Chronic Musculoskeletal Conditions in the Foot and Lower Leg E-Book Book in PDF, ePub and Kindle
Bridging the gap between undergraduate and postgraduate knowledge and experience, this new full colour resource uses an interdisciplinary approach to help manage chronic conditions – osteoarthritis, Achilles tendinopathy, gout, rheumatic diseases, forefoot/rearfoot entities, stress fractures/reactions, cerebral palsy – in the lower limb and foot. Each chapter includes sections on predisposing factors, diagnosis, impairments, function, quality of life and management strategies while highlighting any complex features of a condition which may present. The latest advances are discussed with suggestions for new paths of research – ‘future directions’. The text is further supported by additional commentaries from internationally renowned researchers who highlight the key elements of the work and provide a supplementary perspective of the particular clinical condition. A general view of the patient’s needs is offered throughout, connecting clinical realities to real-world patient experiences. Management of Chronic Conditions in the Foot and Lower Leg is a comprehensive, practical tool that can be used to inform daily decision making in practice as well as to support those who build policy and management strategies in the clinical areas covered. Clear content and structure supported by full colour illustrations Includes less discussed conditions such as gout and cerebral palsy Focus on pain, impairment, function, quality of life and management strategies Critical reflections by experts highlight current clinical practice and thinking in research Provides a sound interpretation of research findings Features patient-reported outcome measures and health related behaviour strategies
Author | : Samir Lutf M. Y. Aleryani |
Publisher | : |
Total Pages | : 226 |
Release | : 1999 |
Genre | : Biotransformation (Metabolism) |
ISBN | : |
Download Role of Free Radicals in the Bioactivation of Nitric Oxide Donors Book in PDF, ePub and Kindle
Author | : Louis J. Ignarro |
Publisher | : Academic Press |
Total Pages | : 1023 |
Release | : 2000-09-13 |
Genre | : Medical |
ISBN | : 0080525032 |
Download Nitric Oxide Book in PDF, ePub and Kindle
Nitric oxide (NO) is a gas that transmits signals in an organism. Signal transmission by a gas that is produced by one cell and which penetrates through membranes and regulates the function of another cell represents an entirely new principle for signaling in biological systems. NO is a signal molecule of key importance for the cardiovascular system acting as a regulator of blood pressure and as a gatekeeper of blood flow to different organs. NO also exerts a series of other functions, such as acting a signal molecule in the nervous system and as a weapon against infections. NO is present in most living creatures and made by many different types of cells. NO research has led to new treatments for treating heart as well as lung diseases, shock, and impotence. Scientists are currently testing whether NO can be used to stop the growth of cancerous tumors, since the gas can induce programmed cell death, apoptosis. This book is the first comprehensive text on nitric oxide to cover all aspects--basic biology, chemistry, pathobiology, effects on various disease states, and therapeutic implications. Edited by Nobel Laureate Louis J. Ignarro, editor of the Academic Press journal, Nitric Oxide Authored by world experts on nitric oxide Includes an overview of basic principles of biology and chemical biology Covers principles of pathobiology, including the nervous system, cardiovascular function, pulmonary function, and immune defense
Author | : Niall Andrew Hogan |
Publisher | : |
Total Pages | : 190 |
Release | : 1998 |
Genre | : Heart beat |
ISBN | : |
Download The Effect of Nitric Oxide Donors on Heart Rate Book in PDF, ePub and Kindle
Author | : |
Publisher | : |
Total Pages | : 394 |
Release | : 2003 |
Genre | : |
ISBN | : |
Download Effect of Nitric Oxide Donors on Myocyte Contractile Function Book in PDF, ePub and Kindle