Nf Kb Rel Transcription Factor Family PDF Download
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| Author | : Hsiou-Chi Liou |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 202 |
| Release | : 2007-02-26 |
| Genre | : Science |
| ISBN | : 0387335730 |
Download NF-kB/Rel Transcription Factor Family Book in PDF, ePub and Kindle
Since its first discovery in the early 90’s, the NF-kB/Rel transcription factor family has drawn the attention of experimental biologists, medical profession, and biotech/pharmaceutical industries for its broad and diverse roles in all aspects of human biology and disease. NF-kB/Rel Transcription Factor Family intends to provide an up-to-date guide to the ever-expanding knowledge in the field of NF-kB/Rel transcription factor family.
| Author | : Shampa Chatterjee |
| Publisher | : Academic Press |
| Total Pages | : 476 |
| Release | : 2017-08-31 |
| Genre | : Medical |
| ISBN | : 0128054026 |
Download Immunity and Inflammation in Health and Disease Book in PDF, ePub and Kindle
Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support provides a comprehensive description of the various pathways by which the vertebrate immune system works, the signals that trigger immune response and how fnew and novel nutraceuticals and functional foods, can be used to contain inflammation and also to boost immunity and immune health. Inflammation is a tool to fight pathogens and the vertebrate immune system has a very complex network of cells to achieve this. However inflammation that goes awry is also the leding cause of several diseases ranging from cardiovascular diseases to diabetes. This book covers the entire gamut from the various cellular players in the inflammation-immune response to its ramifications in terms of protection against pathogens as well as in onset of metabolic, aging and auto-immune related diseases. Finally, the balancing role of dietary nutrients between host defence and immune support is also showcased. The first three scetions explain the various components of the immune system and their modes of activation. The fourth section deals with the ramifications of a robust and execessive inflammatory response. The fifth section is focused on the association between nutrition and immunity and how deficiencies in certain nutrients may affect immunocompetence. The sixth section chapters represent a vision of paradigm shifts within the field and discusses possible future directions. This bool will be a valuable reference for researchers studying immune health either in academia, or in the nutraceutical or functional food industries. Product developers in nutraceutical, supplement, functional food, and health food companies will also appreciate the information presented here. Conceptualizes the key features in natural products which can boost immune function and immune health Explains the intricate mechanistic aspects and balance behind immune health Presents the pathophysiology of several diseases associated with immune system disruption
| Author | : |
| Publisher | : |
| Total Pages | : |
| Release | : 19?? |
| Genre | : |
| ISBN | : 9789535138686 |
Download Gene Expression and Regulation in Mammalian Cells - Transcription Toward the Establishment of Novel Therapeutics Book in PDF, ePub and Kindle
| Author | : Jan-Michael Peters |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 498 |
| Release | : 1998-05-31 |
| Genre | : Science |
| ISBN | : 0306456494 |
Download Ubiquitin and the Biology of the Cell Book in PDF, ePub and Kindle
The last several years have been a landmark period in the ubiquitin field. The breadth of ubiquitin's roles in cell biology was first sketched, and the importance of ubiquitin-dependent proteolysis as a regulatory mechanism gained general acceptance. The many strands of work that led to this new perception are re counted in this book. A consequence of this progress is that the field has grown dramatically since the first book on ubiquitin was published almost a decade ago [M. Rechsteiner (ed. ), Ubiquitin, Plenum Press, 1988]. In this span, students of the cell cycle, transcription, signal transduction, protein sorting, neuropathology, cancer, virology, and immunology have attempted to chart the role of ubi quit in in their particular experimental systems, and this integration of the field into cell biology as a whole continues at a remarkable pace. We hope that for active researchers in the field as well as for newcomers and those on the fence, this book will prove helpful for its breadth, historical perspective, and practical tips. Structural data are now available on many of the components of the ubiquitin pathway. The structures have provided basic insights into the unusual biochemical mechanisms of ubiquitination and proteasome-mediated proteolysis. Because high-speed computer graphics can convey structures more effectively than print media, we have supplemented the figures of the book with a Worldwide Web site that can display the structures in a flexible, viewer-controlled format.
| Author | : Sankar Ghosh |
| Publisher | : CRC Press |
| Total Pages | : 246 |
| Release | : 2006-10-20 |
| Genre | : Medical |
| ISBN | : 1420004271 |
Download Handbook of Transcription Factor NF-kappaB Book in PDF, ePub and Kindle
Recent evidence proving the molecular link between unchecked, chronic inflammation and cancer has implicated the transcription factor NF-kB as a key factor in both inhibiting apoptosis and promoting cell proliferation. Since its initial identification 20 years ago as a simple regulating factor in one small part of the immune response, NF-kB is prov
| Author | : Helmut Brade |
| Publisher | : CRC Press |
| Total Pages | : 968 |
| Release | : 2020-10-28 |
| Genre | : Science |
| ISBN | : 1000110389 |
Download Endotoxin in Health and Disease Book in PDF, ePub and Kindle
Offering a basis for further research into the interactions of hosts and pathogens, this work gathers up-to-date findings, and details basic structures, functions and immunology. It provides descriptions of a variety of experimental endotoxin neutralizing agents, as well as a guide to clinical research initiatives and the latest treatments.
| Author | : Gilles Courtois |
| Publisher | : Springer |
| Total Pages | : 70 |
| Release | : 2015-12-29 |
| Genre | : Science |
| ISBN | : 3319258508 |
Download NF-κB-Related Genetic Diseases Book in PDF, ePub and Kindle
This book presents the diverse clinical, cellular and molecular manifestations of NF-KB-related genetic diseases. It shows that studying patient-related pathologies affecting the components of the NF-KB signaling pathway offers the opportunity to understand the various functions of NF-KB in humans, complementing studies performed with mouse models. In addition, people treating those patients acquire a deeper understanding of the molecular basis of the pathophysiological processes.
| Author | : Elizabeth J. Robertson |
| Publisher | : Oxford University Press, USA |
| Total Pages | : 276 |
| Release | : 1987 |
| Genre | : Cancer cells |
| ISBN | : |
Download Teratocarcinomas and Embryonic Stem Cells Book in PDF, ePub and Kindle
| Author | : David A. Frank |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 358 |
| Release | : 2002-12-31 |
| Genre | : Medical |
| ISBN | : 1402073402 |
Download Signal Transduction in Cancer Book in PDF, ePub and Kindle
One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."
| Author | : Jonathan Soboloff |
| Publisher | : CRC Press |
| Total Pages | : 258 |
| Release | : 2017-03-27 |
| Genre | : Medical |
| ISBN | : 149870509X |
Download Signaling Mechanisms Regulating T Cell Diversity and Function Book in PDF, ePub and Kindle
T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.
