New Bioactive Natural Products From Marine Algae And Cyanobacteria PDF Download

Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download New Bioactive Natural Products From Marine Algae And Cyanobacteria PDF full book. Access full book title New Bioactive Natural Products From Marine Algae And Cyanobacteria.

Structure Elucidation of Bioactive Natural Products from Madagascar Marine Algae and Cyanobacteria

Structure Elucidation of Bioactive Natural Products from Madagascar Marine Algae and Cyanobacteria
Author: Eric Hajaniriana Andrianasolo
Publisher:
Total Pages: 466
Release: 2005
Genre: Algae products
ISBN:

Download Structure Elucidation of Bioactive Natural Products from Madagascar Marine Algae and Cyanobacteria Book in PDF, ePub and Kindle

This thesis is an investigation of the natural products deriving from marine algae and cyanobacteria and has resulted in the discovery of eleven new secondary metabolites. The structure elucidations of these new molecules were performed using a variety of spectroscopic techniques. Four new macrolides were isolated and characterized from the Madagascar marine cyanobacterium Geitlerinema sp. These ankaraholides are structurally similar to the potently cytotoxic swinholides and were found to have cytotoxicities ranging from 178 nM to 354 nM against human lung cancer (NCI-H460) and mouse neuro-2a cell lines. Since swinholide-type compounds were previously localized to the heterotrophic bacteria of sponges, these findings raise intriguing questions about their true metabolic source. Geitlerinema sp. was found to be particularly rich in chemistry, and also produced the new linear lipopeptide mitsoamide with unusual structural features including an animal moiety, a homolysine residue and a polyketide unit (3,7- dimethoxy-5-methyl- nonanedioic acid) (DMNA). A collection of the red marine alga Portieria hornemannii from the south of Madagascar (Tolagniaro, Fort Dauphin), led to the isolation of the previously reported halogenated monoterpene, halomon, and the discovery of three new related metabolites. These molecules were found to inhibit DNA methyltransferase 1 (DNMT-1). As a result of efforts to identify bioactive agents from the marine cyanobacterium Lyngbya majuscula, tanikolide dimer, a novel SIRT2 inhibitor (IC50 = 176 nM), and tanikolide seco-acid were isolated. The depside molecular structure of tanikolide dimer, which is likely a meso compound, was established by NMR, MS and chiral HPLC analyses. The structure of tanikolide dimer raises a number of intriguing configurational and biosynthetic questions for further study. The bioassay guided fractionation of a collection of the brown marine alga Dictyota sp. from Netherland Antilles Playa Fort, led to the identification of a novel HDAC inhibitor with a dolastane carbon skeleton. The novel molecule was also found to possess antimalarial activity. Other known HDAC inhibitors with interesting antimalarial activity have been reported previously, and based on this efficacy against malaria, HDAC appears to be a viable target for the development of antiparasitic agents.


Natural Products From Marine Algae

Natural Products From Marine Algae
Author: Dagmar B. Stengel
Publisher: Humana
Total Pages: 0
Release: 2016-10-13
Genre: Science
ISBN: 9781493952731

Download Natural Products From Marine Algae Book in PDF, ePub and Kindle

This volume provides a fundamental overview of the current state of the art in natural products from marine algae, linking the complex and diverse natural resource with recent developments in extraction, analytical and bioactivity testing methodologies. Natural Products from Marine Algae: Methods and Protocols guides readers through protocols and techniques on algal biotechnology, metabolites, Solid-Liquid Extraction (SLE), Microwave Assisted Extraction (MAE), Liquid Chromatography, Gas Chromatography, Nuclear Magnetic Resonance Spectroscopy, Infra-red spectroscopy and Raman Spectroscopy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Natural Products from Marine Algae: Methods and Protocols hopes to aid scientists unravel and quantify algal chemical diversity and support further marine biotechnological developments.


Bioactive Marine Natural Products

Bioactive Marine Natural Products
Author: Dewan S. Bhakuni
Publisher: Springer Science & Business Media
Total Pages: 397
Release: 2006-06-30
Genre: Science
ISBN: 1402034849

Download Bioactive Marine Natural Products Book in PDF, ePub and Kindle

Bioactive Marine Natural Products is the first book available that covers all aspects of bioactive marine natural products. It fills the void in the literature for bioactive marine natural products. The book covers various aspects of marine natural products and it is hoped that all the major classes of bioactive compounds are included. Different classes of marine organisms and the separation and isolation techniques are discussed. The chemistry and biology of marine toxins, peptides, alkaloids, nucleosides and prostanoids are discussed in detail. Biological, toxicological and clinical evaluations are also dealt with to ensure that the book may be adopted at any stage by any practicing organic chemist or biologist, working in academia or in R and D divisions of pharmaceutical companies. Each chapter in the book includes an abstract to highlight the major points discussed in the text and concluding remarks are given. References to books, monographs, review articles and original papers are provided at the end of each chapter.


Marine Bioactive Compounds

Marine Bioactive Compounds
Author: Maria Hayes
Publisher: Springer Science & Business Media
Total Pages: 239
Release: 2011-11-19
Genre: Medical
ISBN: 1461412471

Download Marine Bioactive Compounds Book in PDF, ePub and Kindle

The aim and scope of this book is to highlight the sources, isolation, characterization and applications of bioactive compounds from the marine environment and to discuss how marine bioactive compounds represent a major market application in food and other industries. It discusses sustainable marine resources of macroalgal origin and gives examples of bioactive compounds isolated from these and other resources, including marine by-product and fisheries waste streams. In addition, it looks at the importance of correct taxonomic characterization.


Marine Microbiology

Marine Microbiology
Author: Se-Kwon Kim
Publisher: John Wiley & Sons
Total Pages: 558
Release: 2013-06-21
Genre: Science
ISBN: 3527665277

Download Marine Microbiology Book in PDF, ePub and Kindle

Deliberately breaking with the classical biology-centered description of marine organisms and their products, this reference emphasizes microbial technology over basic biology, setting it apart from its predecessors. As such, it systematically covers the technology behind high-value compounds for use as pharmaceuticals, nutraceuticals or cosmetics, from prospecting to production issues. Following a definition of the field, the book goes on to address all industrially important aspects of marine microbial biotechnology. The first main part contains a description of the major production organisms, from archaebacteria to cyanobacteria to algae and symbionts, including their genetic engineering. The remaining four parts look at commercially important compounds produced by these microorganisms together with their applications. Throughout, the emphasis is on technological considerations, and the future potential of these organisms or compound classes is discussed. A valuable and forward-looking resource for innovative biotechnologists in industry as well as in academia.


Natural Bioactive Compounds

Natural Bioactive Compounds
Author: Rajeshwar P. Sinha
Publisher: Academic Press
Total Pages: 502
Release: 2020-10-06
Genre: Science
ISBN: 0128206594

Download Natural Bioactive Compounds Book in PDF, ePub and Kindle

Natural Bioactive Compounds: Technological Advancements deals with the latest breakthroughs in the field of screening, characterization and novel applications of natural bioactive compounds from diverse group of organisms ranging from bacteria, viruses, cyanobacteria, algae, fungi, bryophytes, higher plants, sponges, corals and fishes. Written by some of the most reputed scientists in the field, this book introduces the reader to strategies and methods in the search for bioactive natural products. It is an essential read for researchers and students interested in bioactive natural products, their biological and pharmacological properties, their possible use as chemopreventive or chemotherapeutic agents, and other future potential applications. Explores natural sources of bioactive compounds, including cyanobacteria, bacteria, viruses, fungi and higher plants Discusses the potential applications of biological products, such as their use in medicine (antibiotics, cancer research, immunology), as food additives, supplements and technological substances Analyzes the contributions of emerging or developing technologies for the study of bioactive natural compounds (characterization and purification)


Marine Algal Bioactives

Marine Algal Bioactives
Author: Luigi Salvay
Publisher:
Total Pages: 332
Release: 2017-02
Genre:
ISBN: 9781681177007

Download Marine Algal Bioactives Book in PDF, ePub and Kindle

Marine organisms are potentially prolific sources of highly bioactive secondary metabolites that might represent useful leads in the development of new pharmaceutical agents. Algae can be classified into two main groups; first one is the microalgae, which includes blue green algae, flagellates, bacillariophyte (diatoms) etc., and second one is macroalgae which includes green, brown and red algae. Marine algal species produce a variety of compounds that are ultimately beneficial to human health. Marine algae are a famous fragility in some parts of world, and also a well-known source of important food phlorotannin's, pigments and sulfated polysaccharides. Compared to the terrestrial plants and animal-based foods, seaweed is rich in some health-promoting molecules and materials such as, dietary fibre, ω-3 fatty acids, essential amino acids, and vitamins A, B, C, and E. The marine world, due to its phenomenal biodiversity, is a rich natural resource of many biologically active compounds. Many marine organisms live in complex habitats exposed to extreme conditions and, in adapting to new environmental surroundings, they produce a wide variety of secondary (biologically active) metabolites which cannot be found in other organisms. Furthermore, considering its great taxonomic diversity, investigations related to the search of new bioactive compounds from the marine environment can be seen as an almost unlimited field. Marine Algal Bioactive enlightens readers on the numerous bioactive of marine algae in drug discovery and development, ranging from the preliminary research to clinical trial. Increasing knowledge regarding the impact of diet on human health along with state-of-the-art technologies has led to significant nutritional discoveries, product innovations, and mass production on an unprecedented scale. Specifically, naturally occurring bioactive extracts or single compounds thereof, that are believed beneficial to human health, have produced an important and dynamic new extent of research resulting in significant developments in nutritional familiarity. The marine environment signifies a relatively untapped source of functional ingredients that can be useful to various aspects of food processing, storage, and fortification. Furthermore, in this text, several marine-based compounds have been recognised as having varied biological activities, with some reported to interfere with the pathogenesis of diseases.


Algal Toxins in Seafood and Drinking Water

Algal Toxins in Seafood and Drinking Water
Author: Ian R. Falconer
Publisher: Academic Press
Total Pages: 248
Release: 1993-10-28
Genre: Cooking
ISBN:

Download Algal Toxins in Seafood and Drinking Water Book in PDF, ePub and Kindle

Some taxonomic and biologic aspects of toxic dinoflagellates / Karen A. Steidinger -- Methods of analysis for algal toxins: dinoflagellate and diatom toxins / John J. Sullivan -- Mode of action of toxins of seafood poisoning / Daniel G. Baden, Vera L. Trainer -- Paralytic shellfish poisoning / C.Y. Kao -- Diarrhetic shellfish poisoning / Tore Aune, Magne Yndestad -- Ciguatera fish poisoning / Raymond Bagnis -- Control measures in shellfish and finfish industries in the USA / James Hungerford, Marleen Wekell -- Seafood toxins of algal origin and their control in Canada / A.D. Cembella, E. Todd -- Taxonomy of toxic cyanophyceae (Cyanobacteria) / Olav M. Skulberg [and others] -- Measurement of toxins from blue-green algae in water and foodstuffs / Ian R. Falconer -- Mechanism of toxicity of cyclic peptide toxins from blue-green algae / Ian R. Falconer -- Diseases related to freshwater blue-green algal toxins and control measures / Wayne W. Carmichael, Ian R. Falconer.