Neurologic Correlates Of Motor Function In Cerebral Palsy Opportunities For Targeted Treatment PDF Download

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Quantifying the Relationships Among Selective Motor Control, Brain Imaging, Biomechanics and Physical Therapy in Children with Spastic Bilateral Cerebral Palsy

Quantifying the Relationships Among Selective Motor Control, Brain Imaging, Biomechanics and Physical Therapy in Children with Spastic Bilateral Cerebral Palsy
Author: Andy Vuong
Publisher:
Total Pages: 0
Release: 2022
Genre:
ISBN:

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Cerebral palsy (CP) is a motor disorder caused by an injury to the developing fetal or infantbrain. While the corticospinal tract (CST) is related to selective motor control (SMC) function, an underlying deficit in spastic CP, little is known about CST microstructural impairment, its relationship with motor function measures and neuroplasticity in response to a physical therapy intervention focused on intensive practice of lower extremity (LE) SMC exercises. The aim of this dissertation was to study the effect of Camp Leg Power, a novel LE SMC intervention in spastic CP, on measures of white matter (WM) motor tract microstructure and motor function measures. Children with unilateral or bilateral spastic CP born premature were recruited for CampLeg Power. Diffusion-weighted imaging scans were collected for participants with bilateral CP and periventricular leukomalacia (PVL). Children with typical development (TD) were recruited as brain imaging controls. The Selective Control Assessment of the Lower Extremity (SCALE) and the gross motor function measure were collected for all participants with CP. Motor function measures analyzed included the 10-meter walk/run test, 6-minute walk test, stride length during gait and isokinetic knee joint torque. Twenty-three children with spastic CP were enrolled (3 unilateral, 20 bilateral; mean age SD: 10.1 2.8 years; age range: 5.6-16.6 years). Diffusion-weighted imaging scans were evaluated for a subset of 12 participants with spastic bilateral CP and PVL and 12 children with TD (mean age SD: 10.3 1.5 years; age range: 7.5-12.8 years). The CP group exhibited lower anisotropy, damaged myelination, decreased axonal integrity and greater overall diffusivity throughout the whole brain including WM motor tracts relative to TD. The CP group improved their motor function following Camp Leg Power coinciding with improved myelination of brain motor regions suggesting neuroplasticity in response to intervention. SCALE is a strong clinical correlate of brain motor impairment, baseline motor function and post-intervention motor outcomes. This work contributes to the overall understanding of neuroimaging, clinical correlates ofimpaired WM and biomechanics measures, neuroplasticity and motor function changes in response to a novel LE SMC intervention in spastic CP.


Cerebral Palsy

Cerebral Palsy
Author:
Publisher:
Total Pages: 28
Release: 1980
Genre: Cerebral palsied children
ISBN:

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Cerebral Palsy

Cerebral Palsy
Author: Freeman Miller
Publisher: JHU Press
Total Pages: 537
Release: 2006-05-08
Genre: Health & Fitness
ISBN: 0801883547

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When a child has a health problem, parents want answers. But when a child has cerebral palsy, the answers don't come quickly. A diagnosis of this complex group of chronic conditions affecting movement and coordination is difficult to make and is typically delayed until the child is eighteen months old. Although the condition may be mild or severe, even general predictions about long-term prognosis seldom come before the child's second birthday. Written by a team of experts associated with the Cerebral Palsy Program at the Alfred I. duPont Hospital for Children, this authoritative resource provides parents and families with vital information that can help them cope with uncertainty. Thoroughly updated and revised to incorporate the latest medical advances, the second edition is a comprehensive guide to cerebral palsy. The book is organized into three parts. In the first, the authors describe specific patterns of involvement (hemiplegia, diplegia, quadriplegia), explain the medical and psychosocial implications of these conditions, and tell parents how to be effective advocates for their child. In the second part, the authors provide a wealth of practical advice about caregiving from nutrition to mobility. Part three features an extensive alphabetically arranged encyclopedia that defines and describes medical terms and diagnoses, medical and surgical procedures, and orthopedic and other assistive devices. Also included are lists of resources and recommended reading.


Campbell's Physical Therapy for Children Expert Consult - E-Book

Campbell's Physical Therapy for Children Expert Consult - E-Book
Author: Robert Palisano
Publisher: Elsevier Health Sciences
Total Pages: 1051
Release: 2022-08-20
Genre: Medical
ISBN: 0323797970

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Gain a solid foundation in physical therapy for infants, children, and adolescents! Campbell's Physical Therapy for Children, 6th Edition provides essential information on pediatric physical therapy practice, management of children with musculoskeletal, neurological, and cardiopulmonary conditions, and special practice settings. Following the APTA’s Guide to Physical Therapist Practice, this text describes how to examine and evaluate children, select evidence-based interventions, and measure outcomes to help children improve their body functions, activities, and participation. What also sets this book apart is its emphasis on clinical reasoning, decision making, and family-centered care. Written by a team of PT experts led by Robert J. Palisano, this book is ideal for use by students and by clinicians in daily practice. Comprehensive coverage provides a thorough understanding of foundational knowledge for pediatric physical therapy, including social determinants of health, development, motor control, and motor learning, as well as physical therapy management of pediatric disorders, including examination, evaluation, goal setting, the plan of care, and outcomes evaluation. Focus on the elements of patient/client management in the APTA’s Guide to Physical Therapist Practice provides a framework for clinical decision making. Focus on the International Classification of Functioning, Disability, and Health (ICF) of the World Health Organization (WHO) provides a standard language and framework for the description of health and health-related states, including levels of a person’s capacity and performance. Experienced, expert contributors help you prepare to become a Board-Certified Pediatric Clinical Specialist and to succeed on the job. NEW! New chapter on social determinants of health and pediatric healthcare is added to this edition. NEW! New chapter on Down syndrome is added. NEW! 45 case scenarios in the ebook offer practice with clinical reasoning and decision making, and 123 video clips depict children’s movements, examination procedures, and physical therapy interventions. NEW! An ebook version is included with print purchase, providing access to all the text, figures, and references, plus the ability to search, customize content, make notes and highlights, and have content read aloud.


Sensorimotor Control

Sensorimotor Control
Author: Reinhard Dengler
Publisher: IOS Press
Total Pages: 240
Release: 2001
Genre: Medical
ISBN: 9781586030810

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Despite the intensive experimental and theoretical studies for over a century, the general processes involved in neural control of pasture and movement, in learning of motor behaviour in healthy subjects and in adaptation in pathology were and remain a challenging problems for the scientists in the field of sensorimotor control. The book is the outcome of the Advanced Research Workshop Sensorimotor Control, where the focus was on the state and the perspectives of the study in the field.


Balance, Gait, and Falls

Balance, Gait, and Falls
Author:
Publisher: Elsevier
Total Pages: 448
Release: 2018-11-24
Genre: Medical
ISBN: 0444639179

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Balance, Gait, and Falls, Volume 159 presents the latest information on sensorimotor anatomy, sensory integration, gravity and verticality, standing balance, balance perturbations, voluntary stepping and gait initiation, gait and gait adaptability, disorders of balance and gait that result from aging and neurological diseases. The book provides a brief overview of age-related changes in the structure and function of sensorimotor and central processes, with sections specifically devoted to Parkinson’s disease, parkinsonism, cerebellar ataxia, stroke, corticobasal degeneration, multiple sclerosis, Huntington’s disease, dystonia, tremor, Alzheimer’s disease, frontotemporal dementia, cerebral palsy, polio, motor neuron disease, brainstem lesions, spinal lesions, peripheral nerve disease, and psychogenic conditions. Diseases covered have a common structure comprising background and epidemiology, pathology, balance disorders, gait disorders, falls, therapies (including fall prevention), and future directions. Covers all aspects of basic and clinical research on disorders of balance and gait in neurological disease Presents a multidisciplinary review of balance and gait physiology, the epidemiology and natural history of balance and gait impairments in aging, and a broad range of neurological diseases Addresses impairments of balance and gait for basic and clinical researchers in neuroscience, human movement science, physiotherapy and exercise physiology


Dysarthria and Apraxia of Speech

Dysarthria and Apraxia of Speech
Author: Christopher A. Moore
Publisher:
Total Pages: 344
Release: 1991
Genre: Medical
ISBN:

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Derived from a conference on clinical dysarthria in San Antonio, in 1990, 19 papers report on clinical and research developments in neuromotor speech disorders for the benefit of speech-language pathologists and researchers, and graduate students in the field. The sections cover theoretical approaches, intelligibility, specific disorders, physiology, and apraxia. Annotation copyrighted by Book News, Inc., Portland, OR


Movement Disorders in Childhood

Movement Disorders in Childhood
Author: Harvey S. Singer
Publisher: Academic Press
Total Pages: 601
Release: 2015-10-27
Genre: Medical
ISBN: 0124115802

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Movement Disorders in Childhood, Second Edition, provides the most up-to-date information on the diseases and disorders that affect motor control, an important area of specialization within child neurology. Over the past several decades, advances in genetics, neuroimaging, neurophysiology, and other areas of neuroscience have provided new understanding of the underlying etiologies and mechanisms of these conditions as well as new opportunities for more accurate diagnosis and effective treatment. This new edition builds upon the success of the first edition, with comprehensive scientific and clinical updates of all chapters. In addition, there are new chapters on hereditary spastic paraplegia, quantitative motor assessments, autoimmune disorders, and movement disorders in the developmental neuropsychiatric disorders ADHD, OCD, and autism. Additional materials are provided on the latest in drug treatments, computer based strategies for genetic diagnosis, and helpful videos for phenomenology. Provides the only current reference specifically focused on childhood movement disorders Investigates the underlying etiologies and mechanisms of these disorders Completely revised and updated with new materials and a more disease-oriented approach New coverage of genetics and movement disorders, immunology and movement disorders, and an introduction to the latest quantitative analysis New videos of instructive and unusual childhood movement disorders 2016 BMA Medical Book Awards Highly Commended in Neurology