Neuroinflammation And Cns Disorders PDF Download
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Author | : Nicola Woodroofe |
Publisher | : John Wiley & Sons |
Total Pages | : 462 |
Release | : 2014-04-15 |
Genre | : Medical |
ISBN | : 1118406540 |
Download Neuroinflammation and CNS Disorders Book in PDF, ePub and Kindle
The last decade has seen an upsurge of information on the role of immune responses in neurodegenerative disorders. In many of these diseases it is still unclear whether the innate and adaptive responses are pathogenic or play a role in repair, and thus understanding their precise roles is key to controlling these diseases by designing immune-therapeutic approaches. The connection between many neurological diseases is the realisation that the immune and nervous systems are inextricable linked, and that perturbations in this delicate balance are involved in many disorders. This has opened up new avenues for therapeutic approaches to treatment of CNS inflammatory and neurodegenerative disorders. Neuroinflammation and CNS Disorders brings together the very latest information on the interactions between the immune system and central nervous system. The first section of the book highlights the basic concepts in the field whilst the second section, the main body of the book, covers the role of the immune response in specific disorders of the central nervous system. Neuroinflammation and CNS Disorders will provide an invaluable guide for both researchers and clinicians working in this complex and dynamic field.
Author | : Mariela Fernanda Perez |
Publisher | : Frontiers Media SA |
Total Pages | : 396 |
Release | : 2022-01-20 |
Genre | : Science |
ISBN | : 2889741079 |
Download Targeting Neuroinflammation in Central Nervous System Disorders: Uncovering Mechanisms, Pharmacological Targets, and Neuropharmaceutical Developments Book in PDF, ePub and Kindle
Author | : National Academies of Sciences, Engineering, and Medicine |
Publisher | : National Academies Press |
Total Pages | : 89 |
Release | : 2018-03-16 |
Genre | : Medical |
ISBN | : 0309463653 |
Download Biomarkers of Neuroinflammation Book in PDF, ePub and Kindle
Neuroinflammation is a burgeoning area of interest in academia and biopharma, with a broadly acknowledged role in many central nervous system (CNS) disorders. However, there is little agreement on the pathophysiological mechanisms that underlie the manifestations of neuroinflammation in the CNS compartment and how neuroinflammation operates as a driver and also as a consequence of disease in the brain. Moreover, another unclear area is how to translate increased understanding of the mechanisms that underlie neuroinflammation and its manifestations in the CNS to therapeutics. To address these gaps in understanding mechanisms and how to translate that understanding into therapeutics, the Forum on Neuroscience and Nervous System Disorders of the National Academies of Sciences, Engineering, and Medicine convened a workshop on March 20-21, 2017, bringing together key leaders in the field from industry, academia, and governmental agencies to explore the role and mechanisms of neuroinflammation in a variety of CNS diseases. The workshop also considered strategies to advance the identification and validation of biomarkers of neuroinflammation that could accelerate development of therapies, bringing much-needed treatments to patients with disorders ranging from neuroinflammatory diseases such as multiple sclerosis (MS) to neuropsychiatric disorders such as depression. This publication summarizes the presentations and discussions from the workshop.
Author | : Alireza Minagar |
Publisher | : Humana Press |
Total Pages | : 283 |
Release | : 2017-03-20 |
Genre | : Medical |
ISBN | : 331951220X |
Download Inflammatory Disorders of the Nervous System Book in PDF, ePub and Kindle
This thoroughly updated edition covers all clinical aspects of neuroinflammation. The latest developments in pathogenesis and advances in treatment are provided, along with an understanding of the immune system's role and interactions between the activated immune cells, cerebral endothelial cells, and other main components of the immune cascade. Cutting-edge and authoritative, this volume offers practitioners a valuable resource for research and clinical practice.
Author | : Alireza Minagar |
Publisher | : Elsevier |
Total Pages | : 541 |
Release | : 2010-12-17 |
Genre | : Medical |
ISBN | : 0123849144 |
Download Neuroinflammation Book in PDF, ePub and Kindle
Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, and brain trauma as well as meningitis and contributes to the generation of pain. We are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage through tolerance to modulation and repair.This book discusses some of the more common neuro-inflammatory diseases. Topics covered include multiple sclerosis, optic neuritis and Susac syndrome. Comprehensive review of the latest developments in neuroinflammation Includes contributions from leading authorities
Author | : Phillip K. Peterson |
Publisher | : Springer |
Total Pages | : 606 |
Release | : 2014-07-08 |
Genre | : Medical |
ISBN | : 149391071X |
Download Neuroinflammation and Neurodegeneration Book in PDF, ePub and Kindle
State of the art reviews by experts in the fields of neuroscience, immunology, microbiology/infectious diseases and pharmacology addressing the convergence of the immune system (neuroinflammation) and the loss of neurons (neurodegeneration). Many of the diseases that are discussed in the book are of epidemic proportion, e.g., Alzheimer’s disease, Parkinson’s disease, stroke, viral encephalitides and substance abuse. In addition to discussions of the involvement of neuroinflammation and neurodegeneration in these disorders, scientific reviews are presented on the cells and mediators that participate in defense of and damage to the nervous system. With rare exception, no or inadequate treatment exists for the diseases discussed in this book. An underlying premise of the book is that understanding of their shared pathogenic mechanisms will lead to improved therapies. Given the rapid evolution of the field of Neuroimmune Pharmacology, readers will find this book to be the most timely and authoritative reference on the subject of each of its chapters.
Author | : Nihar Jana |
Publisher | : Springer |
Total Pages | : 352 |
Release | : 2016-08-13 |
Genre | : Medical |
ISBN | : 9811017115 |
Download Inflammation: the Common Link in Brain Pathologies Book in PDF, ePub and Kindle
This unifying theme of this book-with sections on mechanisms of defense and neuropathogenesis, neurological diseases, infections of the nervous system, neuropharmacology, and novel therapies-is interactions of the immune and nervous systems. It also discusses the role of inflammation as a key mediator of different brain disorders. There have been significant scientific advances in the multidisciplinary field of neuroimmunology / neuroinflammation in the past decade, and this book, edited under the guidance of Professor P. N. Tandon, fosters communication between those who share an interest in this exciting area, including neuroscientists, immunologists, cell biologists, clinicians and neuropharmacologists.
Author | : H. Kettenmann |
Publisher | : Springer Science & Business Media |
Total Pages | : 260 |
Release | : 2013-03-14 |
Genre | : Medical |
ISBN | : 3662050730 |
Download Neuroinflammation — From Bench to Bedside Book in PDF, ePub and Kindle
Recent work has implicated inflammatory processes in the pathophysiology of a variety of neurodegenerative diseases such as Alzheimer's disease, stroke and multiple sclerosis. In this book leading experts in the field discuss molecular, in vivo and clinical aspects of neuroinflammation. It is hoped, with the wealth of research being conductied in this area, that novel therapeutic targets will be identified which will allow successful therapeutic intervention in a variety of neurodegenerative diseases.
Author | : Yu Tang |
Publisher | : Frontiers Media SA |
Total Pages | : 202 |
Release | : 2020-01-15 |
Genre | : |
ISBN | : 2889634108 |
Download Linking Neuroinflammation and Glial Phenotypic Changes in Neurological Diseases Book in PDF, ePub and Kindle
Author | : Morena Zusso |
Publisher | : Frontiers Media SA |
Total Pages | : 282 |
Release | : 2020-07-14 |
Genre | : |
ISBN | : 2889638545 |
Download Neuroinflammation and its Resolution: From Molecular Mechanisms to Therapeutic Perspectives Book in PDF, ePub and Kindle