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Neurobiology of Mental Illness

Neurobiology of Mental Illness
Author: Dennis S. Charney
Publisher: Oxford University Press
Total Pages: 1259
Release: 2013-07-04
Genre: Medical
ISBN: 0199934959

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Our understanding of the neurobiological basis of psychiatric disease has accelerated in the past five years. The fourth edition of Neurobiology of Mental Illness has been completely revamped given these advances and discoveries on the neurobiologic foundations of psychiatry. Like its predecessors the book begins with an overview of the basic science. The emerging technologies in Section 2 have been extensively redone to match the progress in the field including new chapters on the applications of stem cells, optogenetics, and image guided stimulation to our understanding and treatment of psychiatric disorders. Sections' 3 through 8 pertain to the major psychiatric syndromes-the psychoses, mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood-onset. Each of these sections includes our knowledge of their etiology, pathophysiology, and treatment. The final section discusses special topic areas including the neurobiology of sleep, resilience, social attachment, aggression, personality disorders and eating disorders. In all, there are 32 new chapters in this volume including unique insights on DSM-5, the Research Domain Criteria (RDoC) from NIMH, and a perspective on the continuing challenges of diagnosis given what we know of the brain and the mechanisms pertaining to mental illness. This book provides information from numerous levels of analysis including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. In doing so it translates information from the basic laboratory to the clinical laboratory and finally to clinical treatment. No other book distills the basic science and underpinnings of mental disorders and explains the clinical significance to the scope and breadth of this classic text. The result is an excellent and cutting-edge resource for psychiatric residents, psychiatric researchers and doctoral students in neurochemistry and the neurosciences.


Charney & Nestler's Neurobiology of Mental Illness

Charney & Nestler's Neurobiology of Mental Illness
Author: Dennis S. Charney
Publisher: Oxford University Press
Total Pages: 1025
Release: 2018
Genre: Medical
ISBN: 019068142X

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Preceded by Neurobiology of mental illness / edited by Dennis S. Charney ... [et al.]. 4th ed. 2013.


The Neuroscience of Clinical Psychiatry

The Neuroscience of Clinical Psychiatry
Author: Edmund S. Higgins
Publisher: Lippincott Williams & Wilkins
Total Pages: 334
Release: 2012-11-05
Genre: Medical
ISBN: 1469802007

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Bringing the latest breakthroughs in neuroscience to the clinician, this text provides resident and practicing psychiatrists with a comprehensive, clinically relevant overview of the brain mechanisms underlying behavior and mental illness. The book presents an integrated perspective on the structures and workings of the brain, the mechanisms governing behaviors such as pleasure, aggression, and intelligence, and the pathophysiology of mental disorders. More than 200 two-color illustrations clarify key concepts. Questions and answers at the end of each chapter facilitate review and board preparation. Readers will also have online access to the complete, fully searchable text and a quiz bank of over 150 questions at www.neuroscienceofclinicalpsychiatry.com.


Neurobiology of Mental Illness

Neurobiology of Mental Illness
Author: Dennis S. Charney
Publisher: Oxford University Press
Total Pages: 1504
Release: 2011-05-20
Genre: Medical
ISBN: 9780199857548

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This is a new edition of the first comprehensive text to show how the advances in molecular and cellular biology and in the basic neurosciences have brought the revolution in molecular medicine to the field of psychiatry. The book begins with a review of basic neuroscience and methods for studying neurobiology in human patients then proceeds to discussions of all major psychiatric syndromes with respect to knowledge of their etiology, pathophysiology, and treatment. Emphasis is placed on synthesizing information across numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, and behavior, and in translating information from the basic laboratory to the clinical laboratory and finally to clinical treatment. Editors Dennis Charney and Eric Nestle, along with their six section editors and over 150 contributors, have revised and updated all 80 chapters from the previous edition and have added new chapters on topics relating to, for example, genetics, experimental therapeutics, and late-life mood disorders. Both a textbook and a reference book, Neurobiology of Mental Illness is intended for psychiatrists, neuroscientists, and upper level students.


Brave New Brain

Brave New Brain
Author: Nancy C. Andreasen
Publisher:
Total Pages: 392
Release: 2004
Genre: Génome humain
ISBN: 9780195167283

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Here, leading neuroscientist Nancy Andreasen offers a state-of-the-art look at what we know about the human brain and the human genome--and shows how these two vast branches of knowledge are coming together in a boldly ambitious effort to conquer mental illness. Andreasen gives us an engaging and readable description of how it all works---from billions of neurons, to the tiny thalamus, to the moral monitor in our prefrontal cortex. She shows the progress made in mapping the human genome, whose 30,000 to 40,000 genes are almost all active in the brain. We read gripping stories of the people who develop mental illness, the friends and relatives who share their suffering, the physicians who treat them, and the scientists who study them so that better treatments can be found. Four major disorders are covered--schizophrenia, manic depression, anxiety disorders, and dementia--revealing what causes them and how they affect the mind and brain. Finally, the book shows how the powerful tools of genetics and neuroscience will be combined during the next decades to build healthier brains and minds. By revealing how combining genome mapping with brain mapping can unlock the mysteries of mental illness, Andreasen offers a remarkably fresh perspective on these devastating diseases.


Neurobiology of Psychiatric Disorders

Neurobiology of Psychiatric Disorders
Author: Thomas E Schlaepfer
Publisher: Elsevier
Total Pages: 781
Release: 2012-07-09
Genre: Medical
ISBN: 0444520023

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This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the science defining these disorders and details best practices for psychiatric treatment. Provides a comprehensive review of the scientific foundations of psychiatric disorders and psychiatric treatment Includes detailed results from genetics, molecular biology, brain imaging, and neuropathological, immunological, epidemiological, metabolic, therapeutic and historical aspects of the major psychiatric disorders A "must have" reference and resource for neuroscientists, neurologists, psychiatrists, and clinical psychologists as well as all research scientists investigating disorders of the brain


Neurobiology of Bipolar Disorder

Neurobiology of Bipolar Disorder
Author: Joao Quevedo
Publisher: Academic Press
Total Pages: 472
Release: 2020-11-25
Genre: Medical
ISBN: 012819183X

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The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder


The Neuropsychology of Mental Illness

The Neuropsychology of Mental Illness
Author: Stephen J. Wood
Publisher: Cambridge University Press
Total Pages: 465
Release: 2009-10
Genre: Medical
ISBN: 0521862892

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Describes neuropsychological approaches to the investigation, description, measurement and management of a wide range of mental illnesses.


The Neurobiology-Psychotherapy-Pharmacology Intervention Triangle

The Neurobiology-Psychotherapy-Pharmacology Intervention Triangle
Author: João G. Pereira
Publisher: Vernon Press
Total Pages: 368
Release: 2019-07-30
Genre: Psychology
ISBN: 1622735773

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This book intends to open the debate between three main aspects of clinical practice: psychotherapy (including psychological and philosophical influences), neurobiology and pharmacology. These three main themes are clinically applied in what we call the “Intervention Triangle”. The book will first focus on epistemologically distinct frameworks and gradually attempt to consider the integration of these three fundamental vertexes of practice. These vertexes are substantially unbalanced in the mental health field, and thus, this book tries to make sense of this phenomenon. Unique in its interdisciplinary and comprehensive view of mental health problems and approaches, this book offers a new perspective on unidisciplinary integration that previous publications have not considered. As an innovative contribution to its field, this volume will be particularly relevant to practitioners working towards integrative frameworks. It will also be of interest to students, clinicians and researchers, in particular, those working in psychology, medicine, psychiatry, philosophy, social work, and pharmacy.


Neurobiology of Depression

Neurobiology of Depression
Author: Joao Luciano de Quevedo
Publisher: Academic Press
Total Pages: 471
Release: 2019-01-03
Genre: Medical
ISBN: 0128133341

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Neurobiology of Depression: Road to Novel Therapeutics synthesizes the basic neurobiology of major depressive disorder with discussions on the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing research perspectives and revolutionizing research into depression. These basic foundational understandings on the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research are combined in this book to aid advanced students and researchers in their understanding of MDD. Depression is one of the most common mental-health disorders caused by a variety of genetic, biological, environmental and psychological factors. Major depressive disorder (MDD) is typically treated with first-line antidepressant agents that primarily target monoamine neurotransmission. However, only approximately one-third of patients with MDD achieve remission following a trial with such an antidepressant. Furthermore, MDD is a heterogeneous phenotype, and new frameworks, such as the NIMH Research Domain Criteria (RDoC) may provide a more accurate, biologically based comprehension of the symptomatic heterogeneity of this devastating illness. Aids readers in understanding major depressive disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments, to antidepressants and novel therapeutics Synthesizes discussions on the cellular and molecular mechanisms underlying symptoms with the clinical aspects of depression