Neonatal Hyperbilirubinemia In Preterm Neonates An Issue Of Clinics In Perinatology E Book PDF Download

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Neonatal Hyperbilirubinemia in Preterm Neonates, An Issue of Clinics in Perinatology, E-Book

Neonatal Hyperbilirubinemia in Preterm Neonates, An Issue of Clinics in Perinatology, E-Book
Author: David K. Stevenson
Publisher: Elsevier Health Sciences
Total Pages: 201
Release: 2016-06-10
Genre: Medical
ISBN: 0323446299

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Preterm neonates remain at increased risk for adverse bilirubin-related outcomes, including acute bilirubin encephalopathy relative to term infants. Yet, most vulnerable neonates are likely to benefit from the potent anti-oxidant properties of bilirubin. Evidence-based guidelines for the management of hyperbilirubinemia in preterm infants, however, are lacking. High concentrations of unconjugated bilirubin can cause permanent neurologic damage in infants, evident through magnetic resonance imaging of chronic bilirubin encephalopathy or kernicterus. There is a growing concern that exposures to even moderate concentrations of bilirubin may lead to subtle but permanent neurodevelopmental impairment referred to as bilirubin-induced neurologic dysfunction. Our current use of phototherapy to decrease bilirubin loads and its potential photo-oxidant properties is a biological conundrum that has been questioned in the use of phototherapy for very low birth weight neonates. In this issue of Clinics in Perinatology, we provide updates on the current understanding of the biology, mechanisms of increasing bilirubin load due to hemolysis, decreased bilirubin binding capacity and glucose-6-phosphate dehydrogenase deficiency, as well as clinical strategies to operationalize the thresholds for hyperbilirubinemia interventions in preterm infants.


Care for the Term Newborn, An Issue of Clinics in Perinatology, E-Book

Care for the Term Newborn, An Issue of Clinics in Perinatology, E-Book
Author: Anup Katheria
Publisher: Elsevier Health Sciences
Total Pages: 289
Release: 2021-08-06
Genre: Medical
ISBN: 0323896898

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In this issue of Clinics in Perinatology, Guest Editors Anup Katheria and Lisa Stellwagen bring their considerable expertise to the topic of Care for the Term Newborn. Top experts in the field cover key topics such as delivery room triage and transitions of care; early onset sepsis; congenital infections; postnatal screening & testing; and more. Provides in-depth, clinical reviews on Care for the Term Newborn, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. Contains 14 relevant, practice-oriented topics including Umbilical Cord Management for vigorous and non-vigorous infants; Fetal Circulation and Critical Congenital Cardiac Disease; Alternative Birth Practices, Refusal, and Therapeutic Hesitancy; Prenatal Substance Exposure; and more.


Quality Improvement in Neonatal and Perinatal Medicine, An Issue of Clinics in Perinatology - E-Book

Quality Improvement in Neonatal and Perinatal Medicine, An Issue of Clinics in Perinatology - E-Book
Author: Alan R. Spitzer
Publisher: Elsevier Health Sciences
Total Pages: 321
Release: 2010-04-29
Genre: Medical
ISBN: 1455700533

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This issue of Clinics in Perinatology, guest edited by Drs. Alan Spitzer and Dan Ellsbury, examines Quality Improvement in Neonatal and Perinatal Medicine. The first part of the issue addresses Tools of Quality Improvement and includes articles on The Quality Chasm in Neonatal and Perinatal Medicine; Evaluating the Medical Evidence; The Vermont Oxford Network Database; The Pediatrix Clinical Data Warehouse; Role of Regional Collaboratives: The California Perinatal Quality Care Collaborative Model; A Primer on Quality Improvement Methodology; Using Statistical Process Control Methodology; Human Factors in Quality Improvement, Random Safety Audits, Root Cause Analysis, and Failure Mode and Effects Analysis; Collaboration Between Obstetricians and Neonatologists: Perinatal Safety Programs and Improved Clinical Outcomes; and Pay for Performance: A Business Strategy for Quality Improvement in Neonatal-Perinatal Medicine. The second part of this issue addresses Specific Applications of Documented Quality Improvement Methodology in Neonatal and Perinatal Medicine and includes articles on Delivery Room Intervention-Improving the Outcome, Reducing Retinopathy of Prematurity, Improving Breast Milk Use During and After the NICU Stay, Decreasing Catheter Related Bloodstream Infection, and Decreasing Bronchopulmonary Dysplasia.


Moderate Preterm, Late Preterm, and Early Term Births, An Issue of Clinics in Perinatology

Moderate Preterm, Late Preterm, and Early Term Births, An Issue of Clinics in Perinatology
Author: Lucky Jain
Publisher: Elsevier Health Sciences
Total Pages: 233
Release: 2013-12-28
Genre: Medical
ISBN: 0323261213

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This issue is expected to be in high demand, being extremely valuable to both neonatologists and maternal-fetal medicine physicians. The Guest Editors have put together a very comprehensive issue that looks at the premature infant. Topics include: Moderate Preterm. Late Preterm and Early Term Births: Epidemiology and Trends; Stillbirth Reduction Efforts and Impact on Early Births; Management of Indicated Early Term and Late Preterm Births; Physiological Underpinnings for Clinical Problems in Moderately Preterm, Late Preterm;Brain Maturation in the Second of Half of Pregnancy; Respiratory Disorders in Moderately Preterm, Late Preterm and Early Term Infants; Metabolic and Neurologic Issues in Moderately Preterm, Late Preterm and Early Term Infants; and Quality Initiatives Related to Moderately Preterm, Late Preterm and Early Term Births.


Neonatal Hematology and Transfusion Medicine, An Issue of Clinics in Perinatology

Neonatal Hematology and Transfusion Medicine, An Issue of Clinics in Perinatology
Author: Robert D. Christensen
Publisher: Elsevier Health Sciences
Total Pages: 241
Release: 2015-11-12
Genre: Medical
ISBN: 0323402658

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Recent advances in neonatal hematology, largely made by the authors of these chapters, are likely to generate wide spread and long-term improvements in outcomes, as well as reductions in costs of care. Publication of these advances in a single volume will facilitate dissemination of these techniques and practices. The advances include neuroprotection from erythropoietic stimulators, improved guidelines for platelet transfusions, evidence-based guidelines for FFP administration, improved diagnostic methods for genetic causes of severe neonatal jaundice, more accurate definitions of hematological perturbations in necrotizing enterocolitis and sepsis, and reduction in transfusions and in IVH rates by cord milking/delayed clamping.


Preterm Birth, An Issue of Clinics in Perinatology, E-Book

Preterm Birth, An Issue of Clinics in Perinatology, E-Book
Author: David K. Stevenson
Publisher: Elsevier Health Sciences
Total Pages: 257
Release: 2024-05-09
Genre: Medical
ISBN: 0443130825

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In this issue of Clinics in Perinatology, guest editors Drs. David K. Stevenson and Gary M. Shaw, along with research scientist Ron J. Wong, bring their considerable expertise to the topic of Preterm Birth. Preterm birth is the leading cause of death among children, with one million children dying due to preterm birth before the age of five years. This issue is a key resource for perinatologists who seek to predict and improve outcomes for preterm births, providing actionable clinical information in hopes of reaching the United Nations Sustainable Development Goal to end all preventable deaths of newborns and children aged under five years by 2030. Contains 15 practice-oriented topics including genomics of preterm birth; predicting preterm birth using proteomics; predicting preterm birth using the microbiome; predicting preterm birth using the immunome; a new taxonomy of preterm birth; and more. Provides in-depth clinical reviews of preterm birth, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.


Concepts in Neonatal Nutrition, An Issue of Clinics in Perinatology

Concepts in Neonatal Nutrition, An Issue of Clinics in Perinatology
Author: Brenda Poindexter
Publisher: Elsevier Health Sciences
Total Pages: 217
Release: 2014-06-28
Genre: Medical
ISBN: 0323299474

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Over the past several decades, advances in neonatal nutrition have focused on the provision of early parenteral nutrition and the development of formulas and supplements that most closely approximate maternal breast milk. The overall outcomes for infants, including premature infants, have greatly benefited from these advances, but there are still many nutritional unknowns that impact the lives of neonates. This is an exciting time in neonatal nutrition as the focus has shifted from survival and growth, which are still important goals, to effects of each micro/macronutrient on development, prevention of disease states such as ROP, the effects of neonatal nutrition on future health as an adult, and opportunities to improve long-term neurodevelopmental outcomes by optimal early nutrition. This issue focuses on aspects of enteral and parenteral nutrition that are at the forefront of neonatal care: assessing growth, parenteral nutrition components (including alternate lipid formulations), optimal storage and use of human milk (including donor milk), post-discharge nutrition, and the effects of various micro/macronutrients on long-term developmental outcomes. It is anticipated that the study and implementation of many of these novel concepts into the care of neonates, many of whom are severely premature, will be of value to practitioners, researchers, and, most of all, patients.


Perinatal Interventions to Improve Neonatal Outcomes, an Issue of Clinics in Perinatology

Perinatal Interventions to Improve Neonatal Outcomes, an Issue of Clinics in Perinatology
Author: Ravi Mangal Patel
Publisher: Elsevier
Total Pages:
Release: 2018-06-28
Genre:
ISBN: 9780323584135

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This issue is a must-read for perinatologists and neonatologists who need current advances in treastment and interventions to improve the viability of the neonate. The Guest Editors have put together a concise monograph on the topic, offering the most current clinica review articles on the following topics: Antenatal corticosteroids: Who should we be treating?; Quality improvement strategies to improve care of women in preterm labor; Delivery at term: when, how, and why?; Detection and prevention of perinatal infection; Current strategies to prevent perinatal HIV transmission; Advances in fetal monitoring and association with outcomes; Relationship between perinatal interventions, the maternal-infant microbiome and neonatal outcomes; Understanding outcomes and couseling families at a periviable gestational age; Therapeutic hypothermia - how can we optimize this therapy to further improve outcomes; Reducing CPAP failure in extremely preterm infants; Optimizing caffeine therapy in preterm infants; Improving uptake of key perinatal interventions using state-wide quality collaboratives; Oxygen therapy in the delivery room: What is the right dose?; and Perinatal white matter injury: prevention and long-term outcomes. Readers will leave with the best evidence they need to improve outcomes.


Neonatal-Perinatal Infections: An Update, An Issue of Clinics in Perinatology

Neonatal-Perinatal Infections: An Update, An Issue of Clinics in Perinatology
Author: Brian Smith
Publisher: Elsevier Health Sciences
Total Pages: 241
Release: 2015-03-30
Genre: Medical
ISBN: 0323376363

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In this issue the Guest Editors provide a contemporary look at the epidemiology, clinical manifestations, treatment and outcomes for neonatal-perinatal infections. Contributors include neonatologists, infectious disease, and critical care specialists with a wide variety of research interests in this arena. Readers will be exposed to the latest information on dosing of antibiotics, antivirals, and antifungals. This information is critical in the infant population given the rapid changes in physiology, metabolic pathways and renal elimination that occur over the first months of life. There is an extensive examination of infectious processes that commonly present in infants including meningitis, bloodstream infections, and urinary tract infections. Additional topics include infectious processes affecting the newborn (chorioamnionitis and TORCH infections) and premature infants (necrotizing enterocolitis). Specific pathogens are highlighted in articles on HSV, CMV/VZV, staphylococcal species, and Candida. Finally, the rationale for the most recent changes to guidelines for initiating therapy for early-onset neonatal sepsis are reviewed.