Natural Small Molecule Drugs From Plants PDF Download
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| Author | : Guan-Hua Du |
| Publisher | : Springer |
| Total Pages | : 741 |
| Release | : 2018-11-19 |
| Genre | : Medical |
| ISBN | : 9811080224 |
Download Natural Small Molecule Drugs from Plants Book in PDF, ePub and Kindle
This book discusses 120 types of natural, small-molecule drugs derived from plants. They are grouped into 7 parts according their clinical uses, such as drugs for cardiovascular diseases, for metabolic diseases, for neuropsychiatric diseases, for immune-mediated inflammatory diseases, anti-tumor drugs, and drugs for parasites and bacterial infection. Each chapter systematically summarizes one drug, including its physicochemical properties, sources, pharmacological effects and clinical applications. To help readers understand the drug better, the research and pharmacological activity for each drug is also described, which serves as a salutary lesson for future drug development. Written by frontline researchers, teachers and clinicians working in field of pharmacy and pharmacology it provides an overview of natural, small-molecule drugs derived from plants for researchers in the field.
| Author | : Lixin Zhang |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 380 |
| Release | : 2007-11-17 |
| Genre | : Medical |
| ISBN | : 1592599761 |
Download Natural Products Book in PDF, ePub and Kindle
A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.
| Author | : National Academy of Sciences/Smithsonian Institution |
| Publisher | : National Academies Press |
| Total Pages | : 535 |
| Release | : 1988-01-01 |
| Genre | : Science |
| ISBN | : 0309037395 |
Download Biodiversity Book in PDF, ePub and Kindle
This important book for scientists and nonscientists alike calls attention to a most urgent global problem: the rapidly accelerating loss of plant and animal species to increasing human population pressure and the demands of economic development. Based on a major conference sponsored by the National Academy of Sciences and the Smithsonian Institution, Biodiversity creates a systematic framework for analyzing the problem and searching for possible solutions.
| Author | : Madhathilkovilakathu Haridas |
| Publisher | : Springer Nature |
| Total Pages | : 572 |
| Release | : |
| Genre | : |
| ISBN | : 9819991838 |
Download Drugs from Nature: Targets, Assay Systems and Leads Book in PDF, ePub and Kindle
| Author | : Subhash C. Mandal |
| Publisher | : Elsevier |
| Total Pages | : 776 |
| Release | : 2018-02-16 |
| Genre | : Science |
| ISBN | : 0081021046 |
Download Natural Products and Drug Discovery Book in PDF, ePub and Kindle
Natural Products and Drug Discovery: An Integrated Approach provides an applied overview of the field, from traditional medicinal targets, to cutting-edge molecular techniques. Natural products have always been of key importance to drug discovery, but as modern techniques and technologies have allowed researchers to identify, isolate, extract and synthesize their active compounds in new ways, they are once again coming to the forefront of drug discovery. Combining the potential of traditional medicine with the refinement of modern chemical technology, the use of natural products as the basis for drugs can help in the development of more environmentally sound, economical, and effective drug discovery processes. Natural Products & Drug Discovery: An Integrated Approach reflects on the current changes in this field, giving context to the current shift and using supportive case studies to highlight the challenges and successes faced by researchers in integrating traditional medicinal sources with modern chemical technologies. It therefore acts as a useful reference to medicinal chemists, phytochemists, biochemists, pharma R&D professionals, and drug discovery students and researchers. Reviews the changing role of natural products in drug discovery, integrating traditional knowledge with modern molecular technologies Highlights the potential future role of natural products in preventative medicine Supported by real world case studies throughout
| Author | : Anne E. Osbourn |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 588 |
| Release | : 2009-07-07 |
| Genre | : Science |
| ISBN | : 0387854983 |
Download Plant-derived Natural Products Book in PDF, ePub and Kindle
Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.
| Author | : Rohit Dutt |
| Publisher | : Apple Academic Press |
| Total Pages | : 458 |
| Release | : 2020-11 |
| Genre | : Science |
| ISBN | : 9781003010395 |
Download Promising Drug Molecules of Natural Origin Book in PDF, ePub and Kindle
"This new volume, Promising Drug Molecules of Natural Origin, explores potential beneficial drug substances derived from nature. It presents the general principles, characteristics, evaluation techniques, and applications involved in drug molecules from natural sources, such as plants and marine life. With chapters from renowned experts from around the world, the chapters in this volume address the challenges of standardization of herbal medicines, methods of characterization of natural medicines and phyto-constituents, and quality control methods for herbal medicines. Several chapters in the book focus on the evolution of phyto-constituents in cancer therapeutics, while others deal with applications for other diseases, such as diabetes and neuroinflammatory disorders. The volume also specifically reviews heterocyclic drugs from plants. Key features: Provides an exhaustive overview of drugs originating from nature Covers scientific study protocols for characterization Presents diverse applications and uses for herbal medicines Looks at the use of herbal medicines for specific diseases and health conditions, such as diabetes and neuroinflammatory disorders This volume will be a valuable resource for faculty and advanced students in pharmaceutics as well as researchers, scientists, and industry professionals in medicine and drug development"--
| Author | : Ramarao Poduri |
| Publisher | : Springer Nature |
| Total Pages | : 522 |
| Release | : 2021-02-15 |
| Genre | : Medical |
| ISBN | : 9811555346 |
Download Drug Discovery and Development Book in PDF, ePub and Kindle
This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery. The final chapters introduce readers to stem therapeutics, pharmacokinetics, pharmacovigilance, and toxicological testing. Given its scope, the book will enable research scholars, professionals and young scientists to understand the key fundamentals of drug discovery, including stereochemistry, pharmacokinetics, clinical trials, statistics and toxicology.
| Author | : Mayuri Napagoda |
| Publisher | : Walter de Gruyter GmbH & Co KG |
| Total Pages | : 302 |
| Release | : 2022-04-19 |
| Genre | : Science |
| ISBN | : 3110593653 |
Download Chemistry of Natural Products Book in PDF, ePub and Kindle
Plants produce secondary metabolites that humans harness for their own benefit. About half of drugs currently in clinical use are based on these chemicals found in nature. Chemistry of Natural Products covers secondary metabolites present in medicinal plants and their biosynthesis, biological activities, and isolation and separation techniques. This book is ideal for researchers in the areas of biochemistry, medicine, and pharmacology.
| Author | : Murat Şentürk |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 270 |
| Release | : 2017-03-29 |
| Genre | : Science |
| ISBN | : 9535130579 |
Download Enzyme Inhibitors and Activators Book in PDF, ePub and Kindle
Over the recent years, medicinal chemistry has become responsible for explaining interactions of chemical molecule processes such that many scientists in the life sciences from agronomy to medicine are engaged in medicinal research. This book contains an overview focusing on the research area of enzyme inhibitor and activator, enzyme-catalyzed biotransformation, usage of microbial enzymes, enzymes associated with programmed cell death, natural products as potential enzyme inhibitors, protease inhibitors from plants in insect pest management, peptidases, and renin-angiotensin system. The book provides an overview on basic issues and some of the recent developments in medicinal science and technology. Especially, emphasis is devoted to both experimental and theoretical aspect of modern medicine. The primary target audience for the book includes students, researchers, chemists, molecular biologists, medical doctors, pharmacologists, and professionals who are interested in associated areas. The textbook is written by international scientists with expertise in biochemistry, enzymology, molecular biology, and genetics, many of which are active in biochemical and pharmacological research. I would like to acknowledge the authors for their contribution to the book. We hope that the textbook will enhance the knowledge of scientists in the complexities of some medical approaches; it will stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications of pharmacology.
