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Natural Extracts Using Supercritical Carbon Dioxide

Natural Extracts Using Supercritical Carbon Dioxide
Author: Mamata Mukhopadhyay
Publisher: CRC Press
Total Pages: 362
Release: 2000-06-27
Genre: Medical
ISBN: 142004169X

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Synthesizing research from a wide variety of sources, this work offers a convenient guide to a clean, safe, inexpensive, non-toxic, non-polluting solvent that performs better than most conventional solvents. Natural Extracts Using Supercritical Carbon Dioxide reviews recent developments in the technology and its applications to the food, flavor, fragrance, and pharmaceutical industries. It outlines the many advantages that this method has over traditional methods like steam distillation, solvent extraction, and molecular distillation, and it supports the popular trend toward the use of natural products in these industries.


Supercritical Carbon Dioxide

Supercritical Carbon Dioxide
Author: Evie P. Hayden
Publisher:
Total Pages: 226
Release: 2020-02-14
Genre: Science
ISBN: 9781536174151

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"Supercritical Carbon Dioxide: Functions and Applications presents a constructive overview on the use of supercritical carbon dioxide as an alternative solvent to obtain natural products, instead of using conventional organic solvents. The overview includes the fundamentals, industrial applications, and main experimental findings based on recent studies about supercritical extraction using carbon dioxide. Next, the impregnation of polymer materials with two different ketones with known activity against the main pests of stored products (thymoquinone and R-( )-pulegone) is presented, and the effect of the process variables on ketone loading and the final activity of the impregnated materials is discussed. The authors go on to evaluate the effect of temperature (T: 41-69°C) and CO2 density (D: 843-957 kg/m3) on the extraction yield of oil and bioactive compounds of N. gaditana using supercritical CO2, a technology that allows for the selective extraction of compounds of interest by varying the pressure and temperature conditions, producing natural extracts without the use of liquid organic solvents. Hydrophobic modifying coatings on textile materials made of polyethylene terephthalate were obtained by precipitating a low molecular weight fraction of ultrafine polytetrafluoroethylene. The modifier application conditions are also defined. The closing chapter provides an overview on the principal applications related to the supercritical fluid extraction of active compounds from tobacco and tobacco waste, emphasizing the influence of the most important processing parameters on the extraction yield"--


Solubility in Supercritical Carbon Dioxide

Solubility in Supercritical Carbon Dioxide
Author: Ram B. Gupta
Publisher: CRC Press
Total Pages: 960
Release: 2006-12-06
Genre: Science
ISBN: 1420005995

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Supercritical fluid extraction is an environmentally safe and cost-effective alternative to traditional organic solvents. Carbon dioxide is widely used as the solvent of choice for applications such as caffeine and nicotine extraction due to its mild critical temperature, nontoxicity, nonflammability, and low cost. Introducing the most complete col


Extraction of Natural Products Using Near-Critical Solvents

Extraction of Natural Products Using Near-Critical Solvents
Author: M.B. King
Publisher: Springer Science & Business Media
Total Pages: 335
Release: 2012-12-06
Genre: Science
ISBN: 9401121389

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The aim of this book is to present the current state of the art of extracting natural products with near-critical solvents and to view the possibilities of further extensions of the technique. Relevant background theory is given but does not dominate the book. Carbon dioxide is the near-critical solvent used in most recent applications and inevitably receives prominence. In addition to general descriptions and reviews, the book contains three chapters by indus trial practitioners who describe in detail the operation of their processes and discuss the market for their products. Sections on the design of the pressure vessels and pumps required in these processes and on the acquisition of the data required for design are included. The costing of the processes is also discussed. There is good scope for combining a near-critical extraction step with other process steps in which the properties of near-critical solvents are utilised, for example as a reaction or crystallisation medium and a chapter is devoted to these important aspects. It is hoped that the work will be found to contain a great deal of specific information of use to those already familiar with this field. However the style of presentation and content is such that it will also be useful as an introduction. In particular it will be helpful to those wondering if this form of separation method has anything to offer for them, whether they are engineers, chemists or managers in industry, or in academic or research institutions.


Targeted Extraction of Select Natural Products Using Supercritical Carbon Dioxide

Targeted Extraction of Select Natural Products Using Supercritical Carbon Dioxide
Author: Kari Kramp
Publisher:
Total Pages: 0
Release: 2010
Genre:
ISBN:

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This thesis examined the supercritical carbon dioxide (CO2) extraction (SFE) of targeted secondary metabolites from selected natural products. Phytochemical characterization and determination of biological efficacy was completed using advanced analytical methods and in-vivo bio-assays. More than 500 SFE extracts were generated and characterized. Sample preparation (particle size, moisture content) and extraction parameters (pressure, temperature and flow rate) were investigated and the ability of SFE to extract specific biosynthetic classes of compounds was evaluated. Where warranted, pilot scale studies were conducted for larger scale biological trials. SFE of the neotropical vine, Souroubea sympetala, a traditional medicine used for a culture bound syndrome related to anxiety, resulted in an extract rich in betulinic acid (5.54 +/- 0.24 mg/g) determined by HPLC-APCI/MS. When subjected to validated rodent anxiety behavioral assays (e.g. elevated plus maze (EPM)) the SFE extract demonstrated significant anxiolysis (anti-anxiety) compared to the vehicle control, with a 50% increase in time spent in open arms and a 73% increase in unprotected head dips observed. The significant in-vivo anxiolysis observed provides scientific support for the ethnobotanical use of this traditional medicine and a promising lead for a natural health product (NHP) to treat anxiety. Systematic variation of SFE parameters (pressure and temperature) on pyrethrum (Chrysanthemum cinerariifolium) oleoresin, a natural insecticide, resulted in a residue free pyrethrin concentrate, suitable for organic agricultural applications. The highest pyrethrin concentration (0.531 g/g) and highest ratio of pyrethrins I (pyrethrin I, cinerin I, jasmolin I) to pyrethrins II (pyrethrin II, cinerin II, jasmolin I) (PI:PII = 1.95) was obtained at 40 °C; 10 MPa while 40°C; 30 MPa produced the lowest pyrethrin concentration (0.436 g/g) and lowest ratio of PI:PII (1.87). Total pyrethrin recovery was highest at 40°C; 30 MPa (8.39 g pyrethrins) vs. 40°C; 10 MPa (6.96 g pyrethrins). The insecticidal activity of the SFE extracts of the pyrethrum oleoresin was confirmed (>70% mortality at 48 h) using the Colorado potato beetle (CPB) a major pest of agriculture. SFE of piperamides from black pepper (Piper nigrum), a promising botanical insecticide and synergist, was successful at pressures above 30 MPa and temperatures greater than 50C with total yields greater than 7.87% (CV


Supercritical Fluid Extraction of Nutraceuticals and Bioactive Compounds

Supercritical Fluid Extraction of Nutraceuticals and Bioactive Compounds
Author: Jose L. Martinez
Publisher: CRC Press
Total Pages: 424
Release: 2007-11-28
Genre: Science
ISBN: 1420006517

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Enhanced concern for the quality and safety of food products, increased preference for natural products, and stricter regulations on the residual level of solvents, all contribute to the growing use of supercritical fluid technology as a primary alternative for the extraction, fractionation, and isolation of active ingredients. As a solvent-free p


Fundamentals and Applications of Supercritical Carbon Dioxide (SCO2) Based Power Cycles

Fundamentals and Applications of Supercritical Carbon Dioxide (SCO2) Based Power Cycles
Author: Klaus Brun
Publisher: Woodhead Publishing
Total Pages: 464
Release: 2017-01-09
Genre: Technology & Engineering
ISBN: 0081008058

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Fundamentals and Applications of Supercritical Carbon Dioxide (SCO2) Based Power Cycles aims to provide engineers and researchers with an authoritative overview of research and technology in this area. Part One introduces the technology and reviews the properties of SCO2 relevant to power cycles. Other sections of the book address components for SCO2 power cycles, such as turbomachinery expanders, compressors, recuperators, and design challenges, such as the need for high-temperature materials. Chapters on key applications, including waste heat, nuclear power, fossil energy, geothermal and concentrated solar power are also included. The final section addresses major international research programs. Readers will learn about the attractive features of SC02 power cycles, which include a lower capital cost potential than the traditional cycle, and the compounding performance benefits from a more efficient thermodynamic cycle on balance of plant requirements, fuel use, and emissions. Represents the first book to focus exclusively on SC02 power cycles Contains detailed coverage of cycle fundamentals, key components, and design challenges Addresses the wide range of applications of SC02 power cycles, from more efficient electricity generation, to ship propulsion


Green Extraction of Natural Products

Green Extraction of Natural Products
Author: Farid Chemat
Publisher: John Wiley & Sons
Total Pages: 384
Release: 2016-03-11
Genre: Science
ISBN: 3527676813

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Extraction processes are essential steps in numerous industrial applications from perfume over pharmaceutical to fine chemical industry. Nowadays, there are three key aspects in industrial extraction processes: economy and quality, as well as environmental considerations. This book presents a complete picture of current knowledge on green extraction in terms of innovative processes, original methods, alternative solvents and safe products, and provides the necessary theoretical background as well as industrial application examples and environmental impacts. Each chapter is written by experts in the field and the strong focus on green chemistry throughout the book makes this book a unique reference source. This book is intended to be a first step towards a future cooperation in a new extraction of natural products, built to improve both fundamental and green parameters of the techniques and to increase the amount of extracts obtained from renewable resources with a minimum consumption of energy and solvents, and the maximum safety for operators and the environment.


The Properties of Gases and Liquids 5E

The Properties of Gases and Liquids 5E
Author: Bruce E. Poling
Publisher: McGraw Hill Professional
Total Pages: 802
Release: 2000-11-27
Genre: Technology & Engineering
ISBN: 0071499997

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Must-have reference for processes involving liquids, gases, and mixtures Reap the time-saving, mistake-avoiding benefits enjoyed by thousands of chemical and process design engineers, research scientists, and educators. Properties of Gases and Liquids, Fifth Edition, is an all-inclusive, critical survey of the most reliable estimating methods in use today --now completely rewritten and reorganized by Bruce Poling, John Prausnitz, and John O’Connell to reflect every late-breaking development. You get on-the-spot information for estimating both physical and thermodynamic properties in the absence of experimental data with this property data bank of 600+ compound constants. Bridge the gap between theory and practice with this trusted, irreplaceable, and expert-authored expert guide -- the only book that includes a critical analysis of existing methods as well as hands-on practical recommendations. Areas covered include pure component constants; thermodynamic properties of ideal gases, pure components and mixtures; pressure-volume-temperature relationships; vapor pressures and enthalpies of vaporization of pure fluids; fluid phase equilibria in multicomponent systems; viscosity; thermal conductivity;diffusion coefficients; and surface tension.