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Nanotechnology Tools for Infection Control

Nanotechnology Tools for Infection Control
Author: Alessandro Poma
Publisher: Elsevier
Total Pages: 414
Release: 2024-08-26
Genre: Technology & Engineering
ISBN: 0128239956
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Nanotechnology Tools for Infections Control: Scanning New Horizons on Next-Generation Therapies to Eradicate Pathogens and Fight Drug Resistance provides an overview of recent strategies to build nanotechnology platforms, with a specific focus on biocompatible and biodegradable nanosystems. Particular attention is given to responsive nanoparticles, which are able to sense and respond to specific external stimuli (e.g., temperature, pH). The book includes details of the rationale behind the design of the raw materials, synthetic procedures and characterization techniques. It also introduces a new generation of nanomaterials, commonly named as ‘nanobots’, which are able to self-propel in response to external stimuli. Subsequent sections of the book focus on the applications of nanosystems as an alternative approach to standard antibiotics. The chapters describe their pharmokinetic and dynamics within the body, their ability to cross biological barriers and how they distribute within different body compartments. In this respect, a dedicated section highlights the crucial role of the immune system, as well as of protein corona, in changing the nanoparticles retention within the body. Coverage is also given to describe how nanosystems access different cells and their intracellular trafficking. Provides an overview of the current challenges in infection and immunity, showing how nanosystems can be used to meet them Focuses on the translational potential of nanotechnology for both clinical and commercial applications Assesses the major challenges of effectively using nanotechnology in immunology

Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases

Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases
Author: Mahendra Rai
Publisher: Academic Press
Total Pages: 341
Release: 2015-05-23
Genre: Technology & Engineering
ISBN: 0128014717
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Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases delivers comprehensive coverage of the application of nanotechnology to pressing problems in infectious disease. This text equips readers with cutting-edge knowledge of promising developments and future prospects in nanotechnology, paying special attention to microbes that are now resistant to conventional antibiotics, a concerning problem in modern medicine. Readers will find a thorough discussion of this new approach to infectious disease treatment, including the reasons nanotechnology presents a promising avenue for the diagnosis, treatment, and prophylaxis of infectious diseases. Provides a comprehensive overview of the use of nanotechnology in the treatment and diagnosis of infectious diseases Covers all common types of infective agents, including bacteria, viruses, fungi, and protozoa, along with their vectors, ticks, mosquitoes, flies, etc. Delivers commentary from an international researcher base, providing insights across differing economic statuses Includes a foundation of basic nanotechnological concepts to aid in designing new strategies to combat several pathogenic diseases and cancer Illustrates the high antimicrobial potential of nanoparticles, ultimately demonstrating how they are a promising alternative class that can be successfully used in fighting a myriad of infections

Infectious Diseases and Nanomedicine I

Infectious Diseases and Nanomedicine I
Author: Rameshwar Adhikari
Publisher: Springer Science & Business Media
Total Pages: 127
Release: 2014-03-11
Genre: Science
ISBN: 8132217772
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The book addresses the interdisciplinary scientific approach for the systemic understanding of connections between major human diseases and their treatment regime by applying the tools and techniques of nanotechnology. It also highlights the interdisciplinary collaborative researches for innovation in Biomedical Sciences. The book is a first volume which presents collection of best papers presented in the First International Conference on Infectious Diseases and Nanomedicine held during Dec. 15-18, 2012 in Kathmandu, Nepal. The book focuses mainly on the topics: emerging infectious diseases; antimicrobial agents, vaccines and immunity; drug design, drug delivery and tissue engineering and nanomaterials and biomedical materials.

Nanoscience and Nanotechnology for Smart Prevention, Diagnostics and Therapeutics

Nanoscience and Nanotechnology for Smart Prevention, Diagnostics and Therapeutics
Author: Sathish-Kumar Kamaraj
Publisher: John Wiley & Sons
Total Pages: 420
Release: 2024-07-30
Genre: Science
ISBN: 1394174578
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The book presents the fundamentals of nanomaterials, discusses the direct applications of nanomaterials to the biomedical sector, and explores the potential therapeutic applications of nanotheranostics. This book focuses on the fundamental features of various nanomaterials that are related to the development of biomedical technologies. These fundamental qualities are broken up into three parts: prevention, diagnostics, and therapeutics. When it comes to infectious diseases, prevention is of the utmost importance. Highly advanced nanomaterials including silver, titanium, graphene-based filters, and copper nanoparticles are used to fight infectious illnesses. Once the symptoms have been recognized in the patients, through the use of effective and straightforward nanodiagnostic techniques, the diseases can be accurately localized in either a qualitative or quantitative manner. Nanodiagnostics tools currently dominate the field of biomedical diagnostics because of their high degree of accuracy, low requirement for samples and reagents, user-friendliness, portability, and capacity to perform point-of-care (POC) applications. Nanomaterials are widely used in imaging due to many factors, including: their signal generation and amplification abilities; the ongoing development of reliant new imaging techniques, such as photoacoustic imaging and Raman imaging; their targeting potential, due to the possibility of functionalizing their surface with cancer-targeting moieties; their multimodality, since some nanomaterials can generate signals for more than one imaging technique; and their affordability. Modern therapeutics explores the various nanotechnological advances to cure the site-specific cancer treatment most prominently. The book explores the fundamentals of nanomaterials and discloses their direct application to the biomedical field. Finally, the book discusses future therapeutic applications of nanotheranostics. Audience The book will be read by scientists, researchers, and post-graduate students in the biomedical-related engineering field, nanoscience and nanotechnology, materials science, and bionanotechnology.

Nanoparticles in Modern Antimicrobial and Antiviral Applications

Nanoparticles in Modern Antimicrobial and Antiviral Applications
Author: Varaprasad Kokkarachedu
Publisher: Springer
Total Pages: 0
Release: 2024-03-19
Genre: Science
ISBN: 9783031500923
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Nanotechnology-based nanomaterials have revolutionized the field of advanced medical applications by offering new possibilities for treatment and diagnosis. Nano-form materials have become increasingly important in modern healthcare due to their ability to improve bioactivity and therapeutic efficiency. For example, nanomaterials can target specific cells or tissues in the body, which can result in more effective treatments with fewer side effects. However, it is important to carefully control the toxicity of nanomedicine and study its potential toxic effects to ensure patient safety. Moreover, nanomaterials have shown promise in controlling various types of bacteria, viruses, and even SARS-CoV-2. Their small size and unique properties make them effective tools for combating infectious diseases. This book, "Nanoparticles in Modern Antimicrobial and Antiviral Applications," aims to address key issues related to nanoparticles and their potential applications in healthcare. The book covers topics such as encapsulated polymer systems and their potential applications in COVID-19 treatment, which are not commonly found in other books. As such, it is a valuable resource for those interested in this field and can provide new insights into the use of nanomaterials for medical applications.

Infectious Diseases and Nanomedicine II

Infectious Diseases and Nanomedicine II
Author: Rameshwar Adhikari
Publisher: Springer
Total Pages: 0
Release: 2016-09-03
Genre: Science
ISBN: 9788132229032
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The book addresses the interdisciplinary scientific approach for the systemic understanding of connections between major human diseases and their treatment regime by applying the tools and techniques of nanotechnology. It also highlights the interdisciplinary collaborative researches for innovation in Biomedical Sciences. The book is a second volume which presents collection of best papers presented in the First International Conference on Infectious Diseases and Nanomedicine held during Dec. 15-18, 2012 in Kathmandu, Nepal. The book focuses mainly on the topics: emerging infectious diseases; antimicrobial agents, vaccines and immunity; drug design, drug delivery and tissue engineering and nanomaterials and biomedical materials.

Nanomedicines for the Prevention and Treatment of Infectious Diseases

Nanomedicines for the Prevention and Treatment of Infectious Diseases
Author: Vandana B. Patravale
Publisher: Springer Nature
Total Pages: 415
Release: 2023-12-02
Genre: Medical
ISBN: 3031390202
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The COVID-19 pandemic has altered the world and reiterated the perpetual need for the development of effective strategies for the prevention and treatment of infectious diseases. While globally prevalent infectious diseases receive extensive attention in terms of drug development and delivery, the neglected and/or emerging infectious diseases that affect developing countries are often overlooked. Additionally, the therapeutic efficacy of existing anti-infective agents is often limited due to sub-optimal biopharmaceutical properties, sub-therapeutic levels of the drugs at the infection site due to various physiological barriers, the expulsion of the drug by efflux transporters, and the emergence of drug-resistant strains. From the commercialization of AmBisome® to the emergency authorization of mRNA-based vaccines, nanotechnology has played a vital role in the prevention and treatment of infectious diseases. More importantly, nanotechnology has enabled the effective utilization of existing armamentarium against infectious diseases leading to improved therapeutic outcomes with a concomitant reduction in the side effects associated with anti-infective agents. In particular, nanotechnology can bring about a paradigm shift in the management of neglected and emerging infectious diseases and may compensate for the lack of drug discovery efforts. While there are several books dedicated to pharmaceutical and/or biomedical applications of nanotechnology or nanotechnology for cancer therapy a comprehensive book focusing on the prevention and/or treatment of viral, bacterial, fungal, and parasitic infections is not available. This book addresses an unmet need in pharmaceutical and medical education. This book provides a comprehensive and up-to-date overview of the latest advancements in nanomedicine, which show great potential for preventing and treating infectious diseases. Covering a wide range of topics, it explores various formulation strategies for combating microbial, fungal, parasitic, and viral infections. The book emphasizes the advantages of nano-scale vaccines over traditional ones and discusses their production. It also examines feasible treatment approaches for diseases like malaria, trypanosomiasis, candidiasis, Hepatitis B, HIV, and the ongoing COVID-19 pandemic. Additionally, it highlights the role of nano-adjuvants in vaccine development, as well as the use of peptide antibiotics and pulmonary delivery of drugs, which open up new possibilities in fighting infectious diseases. Furthermore, the book explores the critical role of nanomedicine in addressing veterinary parasitic infections. The emergence of nanotechnology has led to novel strategies for diagnosing, treating, and preventing parasitic infections in animals. In summary, this book offers a comprehensive description of clinically viable and investigational nanotechnology-enabled medicines (nanomedicines) for the prevention and treatment of globally prevalent, neglected, and emerging infectious diseases.

Applications of Nanobiotechnology for Neglected Tropical Diseases

Applications of Nanobiotechnology for Neglected Tropical Diseases
Author: Fabio Rocha Formiga
Publisher: Academic Press
Total Pages: 610
Release: 2021-02-20
Genre: Medical
ISBN: 0128211016
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Applications of Nanobiotechnology for Neglected Tropical Diseases describes recent advances in nanobiotechnology that can be applied to reducing the global disease burden of neglected tropical diseases (NTDs). The book explores the application of nanotechnology on the development of safe, effective, and reliable tools to prevent, diagnose, and treat NTDs. Furthermore, Applications of Nanobiotechnology for Neglected Tropical Diseases includes multidisciplinary content, combining knowledge from biochemistry, medicinal chemistry, material sciences, pharmacology, and pharmaceutics. The book is divided into three main parts, each outlining one major type of approach: (1) nano-based approaches for prevention, (2) nano-diagnostics and detection, and (3) nanotherapeutics. Each part contains chapters that delve into the different applications of the type of approach being presented in that part. A discussion of other approaches against NTD follows these three parts. This book is remarkable in its ability to encompass and thoroughly explain the latest techniques in nanobiotechnology, from basic research to patient-oriented investigation. Offers a broad overview of nanobiotechnology applied to the prevention, diagnostics, and treatment of NTDs Presents cutting-edge recent advances in nanobiotechnology, focusing on diseases reported by the World Health Organization’s NTDs Roadmap (e.g., leishmaniasis, malaria, schistosomiasis, filariasis, etc.) Provides a deep discussion about ground-breaking approaches designed to meet the medical needs of patients suffering from NTDs Gives examples of multidisciplinary investigations into NTDs, from research labs to clinics

The Clinical Nanomedicine Handbook

The Clinical Nanomedicine Handbook
Author: Sara Brenner
Publisher: CRC Press
Total Pages: 365
Release: 2017-11-22
Genre:
ISBN: 9781138075788
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Designed to foster a stronger awareness and exploration of the subject by practicing clinicians, medical researchers and scientists, The Clinical Nanomedicine Handbook discusses the integration of nanotechnology, biology, and medicine from a clinical point of view. The book highlights relevant research and applications by specialty; it examines nanotechnology in depth, and the potential to solve medical problems. It also increases literacy in nanotechnology, and allows for more effective communication and collaboration between disciplines. Details worldwide developments in nanomedicine Provides a comprehensive roadmap of the state of nanomedicine in numerous medical specialties Bridges the gap between basic science research, engineering, nanotechnology, and medicine This text discusses what nanomedicine is, how it is currently used, and considers its potential for future applications. It serves as a reference for clinicians, including physicians, nurses, health-care providers, dentists, scientists, and researchers involved in clinical applications of nanotechnology.