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Fast Facts: Myeloproliferative Neoplasms

Fast Facts: Myeloproliferative Neoplasms
Author: R.A. Mesa
Publisher: Karger Medical and Scientific Publishers
Total Pages: 117
Release: 2019-02-11
Genre: Medical
ISBN: 1910797804

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Presentation of the myeloproliferative neoplasms (MPNs) varies widely, and correct diagnosis and management can be challenging, and is becoming more complex as understanding of the underlying molecular basis for these disorders emerges. Appropriate management is increasingly informed by accurate risk stratification founded on understanding of cytogenetic and molecular markers, as well as the clinical presentation. 'Fast Facts: myeloproliferative neoplasms' focuses on the three most common chronic MPNs: • Essential thrombocythemia (ET) – characterized by increased platelet count • Polycythemia vera (PV) – characterized by excessive production of red blood cells • Primary myelofibrosis – a more severe and heterogenous disorder that may overlap with ET and PV but is commonly associated with anemia. Written by two leading experts in the field, Fast Facts: myeloproliferative neoplasms provides concise, up-to-date and practical guidance on the accurate diagnosis, risk stratification and management of these MPNs. It also provides key insights into our growing understanding of the underlying molecular and genetic basis of these disorders, and how this is informing risk stratification and management strategies. This concise handbook will be invaluable to clinicians, medical students, nurses, pharmacists and scientists in understanding and overcoming the everyday and rarer challenges associated with MPN.


Managing Myeloproliferative Neoplasms

Managing Myeloproliferative Neoplasms
Author: Ruben A. Mesa
Publisher: Cambridge University Press
Total Pages: 207
Release: 2016-03-31
Genre: Medical
ISBN: 1316033775

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This is a concise, practical, case-based book documenting examples and scenarios that will help you manage challenging clinical issues for patients with myeloproliferative neoplasms. The editors and authors have strived to distil the very latest information in this rapidly advancing field in a way that will help you to update your practice and manage your patients. The key focuses are: diagnosis, both standard and challenging; both day-to-day management as well as special situations such as surgery, thrombotic events and pregnancy; and finally, managing evolving situations with MPN such as progression to acute myeloid leukemia. This book is an outstanding resource that includes a discussion of both classical myeloproliferative neoplasms, such as essential thrombocythemia, polycythemia vera and myelofibrosis, and also less common disorders such as systemic mast cell disease, hypereosinophilia, MPN/MBS overlap syndromes and atypical CML, amongst others. This book is a practical reference for practitioners, hematologists, medical oncologists and trainees.


Myeloproliferative Neoplasms

Myeloproliferative Neoplasms
Author: Tiziano Barbui
Publisher: Springer Science & Business Media
Total Pages: 235
Release: 2012-02-03
Genre: Medical
ISBN: 3642249884

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This book focuses on three of the main categories of myeloproliferative neoplasm: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Relevant laboratory and clinical advances are comprehensively covered, and great emphasis is placed on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.


Oxford Specialist Handbook: Myeloproliferative Neoplasms

Oxford Specialist Handbook: Myeloproliferative Neoplasms
Author: Tariq I. Mughal
Publisher: Oxford University Press
Total Pages: 432
Release: 2020-09-24
Genre: Medical
ISBN: 0191061735

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Our understanding of myeloproliferative neoplasms (MPN) disorders, a group of clonal haematological malignancies characterized by excessive accumulation of one or more myeloid cell lineages, has grown considerably over the past four decades. Myeloproliferative Neoplasms offers a detailed evidence-based guide to MPNs in an easily accessible format, structured to facilitate learning specialist information by presenting core information in 'bite size' chunks. Each chapter summarises the state-of-the art preclinical and clinical knowledge, and its impact on the clinical management of patients with MPNs. This practical guide, written by experts in the field, is essential reading for oncologists, haematologists, and other health care professionals interested in the field of MPNs.


Fast Facts: Myeloproliferative Neoplasms

Fast Facts: Myeloproliferative Neoplasms
Author: Ruben A. Mesa
Publisher: Karger Medical and Scientific Publishers
Total Pages: 117
Release: 2019
Genre: Medical
ISBN: 1910797790

Download Fast Facts: Myeloproliferative Neoplasms Book in PDF, ePub and Kindle

Presentation of the myeloproliferative neoplasms (MPNs) varies widely, and correct diagnosis and management can be challenging, and is becoming more complex as understanding of the underlying molecular basis for these disorders emerges. Appropriate management is increasingly informed by accurate risk stratification founded on understanding of cytogenetic and molecular markers, as well as the clinical presentation. 'Fast Facts: myeloproliferative neoplasms' focuses on the three most common chronic MPNs: * Essential thrombocythemia (ET) - characterized by increased platelet count * Polycythemia vera (PV) - characterized by excessive production of red blood cells * Primary myelofibrosis - a more severe and heterogenous disorder that may overlap with ET and PV but is commonly associated with anemia. Written by two leading experts in the field, Fast Facts: myeloproliferative neoplasms provides concise, up-to-date and practical guidance on the accurate diagnosis, risk stratification and management of these MPNs. It also provides key insights into our growing understanding of the underlying molecular and genetic basis of these disorders, and how this is informing risk stratification and management strategies. This concise handbook will be invaluable to clinicians, medical students, nurses, pharmacists and scientists in understanding and overcoming the everyday and rarer challenges associated with MPN.


Myeloproliferative Neoplasms

Myeloproliferative Neoplasms
Author: Tiziano Barbui
Publisher: Springer Science & Business Media
Total Pages: 235
Release: 2012-01-10
Genre: Medical
ISBN: 3642249892

Download Myeloproliferative Neoplasms Book in PDF, ePub and Kindle

This book focuses on three of the main categories of myeloproliferative neoplasm: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Relevant laboratory and clinical advances are comprehensively covered, and great emphasis is placed on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.


Myeloproliferative Neoplasms

Myeloproliferative Neoplasms
Author: Srdan Verstovsek
Publisher: Springer Science & Business Media
Total Pages: 233
Release: 2010-10-17
Genre: Medical
ISBN: 1607612666

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This succinct resource provides an ideal balance of the biology and practical therapeutic strategies for classic and non-classic BCR-ABL-negative myeloproliferative neoplasms. Utilizing current World Health Organization nomenclature, classification, and diagnostic criteria, international experts have assembled to convey the most up-to-date knowledge in this rapidly evolving field. The opening chapters cover the diagnosis and classification, genetics, cytogenetic findings, and prognostic factors of MPNs. Further chapters explore therapies specific to the different disease entities, including polycythemia vera, essential thrombocytopenia, myelofibrosis, and eosinophilic disorders, and mastocytosis. Unique areas of discussion include JAK2 inhibitor therapy, hematopoietic stem cell transplantation, and blastic transformation. A valuable reference for practicing hematologists, this forefront book enriches our understanding of recent discoveries and their impact on conventional and investigational treatments.


Chronic Myeloproliferative Disorders

Chronic Myeloproliferative Disorders
Author: Tariq Mughal
Publisher: CRC Press
Total Pages: 0
Release: 2008-08-27
Genre: Medical
ISBN: 9780415415989

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With the new classification of chronic myeloproliferative disorders, and the rise of interest in molecularly targeted therapies, this timely text brings together international experts on the topic to discuss the current technologies and their implications for the treatment of patients. This title comprehensively covers chronic myeloid leukemia and Ph-negative chronic myeloproliferative disorders and is an essential resource for all practitioners in Hematologic Oncology.


Myeloproliferative Neoplasms, An Issue of Hematology/Oncology Clinics of North America

Myeloproliferative Neoplasms, An Issue of Hematology/Oncology Clinics of North America
Author: John Mascarenhas
Publisher: Elsevier Health Sciences
Total Pages: 240
Release: 2021-02-27
Genre: Medical
ISBN: 0323795897

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This issue of Hematology/Oncology Clinics, guest edited by Drs. Ronald Hoffman, Ross Levine, John Mascarenhas, and Raajit Rampal, is dedicated to Myeloproliferative Neoplasms. This issue is one of six selected each year by the series consulting editors, Drs. George P. Canellos and Edward J. Benz. Topics in this issue include—but are not limited to— Overview of pathophysiology and potential drug targets, The role of the megakaryocyte, Epigenetics, Genetics, Novel technologies for understanding MPN biology, Important pathology considerations, Current Clinical investigations, Quality of life, Application of stem cell therapy, Immunotherapy approaches, Clinical unmet needs in ET/PV, Accelerated and blast phase MPNs, Epidemiology, Thrombotic and hemorrhagic complications, Murine modeling, The microenvironment in MPNs, MDS/MPN overlap syndrome, and Advancing effective clinical trial designs.


Living Well with a Myeloproliferative Neoplasm (MPN)

Living Well with a Myeloproliferative Neoplasm (MPN)
Author: Gowin Krisstina
Publisher: Spry Publishing
Total Pages: 157
Release: 2019-02-14
Genre: Medical
ISBN: 1938170938

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The journey through a diagnosis of MPN is different for each person and there is no road map that will work for everyone. In her book, LIVING WELL with a Myeloproliferative Neoplasm, Dr. Krisstina Gowin provides an essential guide to treatment options and symptom management, while helping patients and their caregivers take an informed and active role in getting quality care, communicating with their healthcare team, and developing a support system. As importantly, she addresses all aspects of the patient—body, mind, psychosocial and spiritual health—promoting overall wellness in bodies already challenged by disease. By following Dr. Gowin’s integrative approach— combining traditional and complementary therapies—MPN patients can get started on a path to living the best life possible every day. -- Gowin