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Buruli Ulcer

Buruli Ulcer
Author: Gerd Pluschke
Publisher: Springer
Total Pages: 287
Release: 2019-04-29
Genre: Medical
ISBN: 3030111148
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A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans.

Mycobacterium ulcerans

Mycobacterium ulcerans
Author: Gerd Pluschke
Publisher: Humana
Total Pages: 0
Release: 2022-10-14
Genre: Science
ISBN: 9781071617816
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This volume explores the latest techniques used to study Mycobacterium ulcerans, and more specifically M. ulcerans disease (Buruli ulcer). The chapters in this book are organized into three parts and cover methods for the detection of M. ulcerans and the analysis of host-pathogen interaction; the quantification and characterization of mycolactone, the macrolide toxin of M. ulcerans; and drug development against M. ulcerans. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mycobacterium ulcerans: Methods and Protocols is a valuable resource that helps scientists advance their research on Buruli ulcer, which is still an under-researched field in infection biology.

Mycobacterial Skin Infections

Mycobacterial Skin Infections
Author: Domenico Bonamonte
Publisher: Springer
Total Pages: 398
Release: 2017-09-04
Genre: Medical
ISBN: 3319485385
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This well-illustrated book is a comprehensive guide to the cutaneous clinical presentations of mycobacterial infections. The Mycobacterium genus includes over 170 species, nontuberculous mycobacteria (NTM) having been added to the obligate human pathogens such as M. tuberculosis and M. leprae. NTM are widely distributed in the environment with high isolation rates worldwide; the skin is a major target with variable clinical manifestations. A current resurgence in tuberculosis is aggravated by the synergy with human immunodeficiency virus, the breakdown of health care systems, and the rise in multidrug-resistant disease, as the incidence of leprosy remains stable, at around 250,000 new cases annually, regardless of effective antibiotic therapy. Presentations of various cutaneous infections caused by mycobacteria may be overlooked by clinicians owing the lack of familiarity with tuberculosis, leprosy, and the related NTM clinical features. This handy guide will help the dermatologist to spot the different clinical manifestations, make a prompt diagnosis, and apply effective treatment.

Infections in Systemic Autoimmune Diseases: Risk Factors and Management

Infections in Systemic Autoimmune Diseases: Risk Factors and Management
Author:
Publisher: Elsevier
Total Pages: 228
Release: 2020-03-24
Genre: Medical
ISBN: 044464217X
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Infections in Systemic Autoimmune Diseases: Risk Factors and Management, Volume Sixteen describes the state-of-the-art of the risk factors and management treating the most common systemic autoimmune diseases (SADS). This updated volume consists of an introductory chapter that provides a brief overview of what different types of infectious diseases exist, followed by eight chapters detailing risk factors, guidelines and recommendations per different disease and bacterial infections. International in scope, the list of more than 20 contributors from Europa and America reads like a who's who of clinical researchers in the field. Written by leading international clinical/surgical and scientific experts on Infection problems in systemic autoimmune diseases Provides a practical guide to the safer treatment of infections in patients with autoimmune diseases Includes a number of problems and recommendation that cannot be found in other books Designed as a 'guide to clinical practice' for management and risk interventions required by patients with SAD's

Tuberculosis

Tuberculosis
Author: David Schlossberg
Publisher: Springer Science & Business Media
Total Pages: 226
Release: 2012-12-06
Genre: Medical
ISBN: 1468403052
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Completely revised and updated, this comprehensive resource covers the epidemiology, pathogenesis, varied clinical manifestations, treatment and prevention of tuberculosis. All of the extra-pulmonary as well as pulmonary manifestations of tuberculosis are covered. Atypical mycobacterial infection is detailed. A special feature of this second edition is the new material on AIDS, which is now known to be complicated by tuberculosis infection.

Biology of Mycobacterial Lipids

Biology of Mycobacterial Lipids
Author: Zeeshan Fatima
Publisher: Academic Press
Total Pages: 316
Release: 2022-06-03
Genre: Science
ISBN: 0323919448
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Biology of Mycobacterial Lipids covers various topics pertaining to the advancements and current research in the field of mycobacterial lipids, and on the significant progress in lipidomics, in recent times. The chapters present comprehensive, yet systematic cutting-edge research, comprising mycobacterial lipid terminologies, classifications, biosynthetic pathways, tools and techniques, and functional burgeoning. This unique reference book has contributions from pioneer researchers, experts, and eminent veterans from around the globe. It covers ground-breaking work that will bridge the gap between understanding biochemical patterns related to virulence, pathogenesis, and resistance and elucidating new targets for drug design, identifying biomarkers for predicting risk, early diagnosis, and therapeutic outcome. Covers major biochemical aspects of mycobacterial lipids, nomenclature, structure and classification, and metabolic pathways Focuses on recent trends and state-of-the-art technology, used in mycobacterial lipids study Brings together the functional aspects of mycobacterial lipidome, involvement of lipids in cellular network and signaling, its involvement in virulence and resistance, and host factor manipulations Highlights the discovery of lipid biomarkers, for diagnostic and therapeutic interventions, using mycobacterial lipidomic studies Presents lipids at the interface of various other biomolecules with integrative omics aspects

Leong's Manual of Diagnostic Antibodies for Immunohistology

Leong's Manual of Diagnostic Antibodies for Immunohistology
Author: Runjan Chetty
Publisher: Cambridge University Press
Total Pages: 525
Release: 2016-11-28
Genre: Medical
ISBN: 1316592065
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Providing a unique A-Z guide to antibodies for immunohistology, this is an indispensable source for pathologists to ensure the correct application of immunohistochemistry in daily practice. Each entry includes commercial sources, clones, descriptions of stained proteins/epitopes, the full staining spectrum of normal and tumor tissues, staining pattern and cellular localization, the range of conditions of immunoreactivity, and pitfalls of the antibody's immunoprofile, giving pathologists a truly thorough quick-reference guide to sources, preparation and applications of specific antibodies. Appendices provide useful quick-reference tables of antibody panels for differential diagnoses, as well as summaries of diagnostic applications. Expanded from previous editions with over forty new entries, this handbook for diagnostic, therapeutic, prognostic and research applications of antibodies is an essential desktop book for practicing pathologists as well as researchers, residents and trainees.

Nontuberculous Mycobacterial Disease

Nontuberculous Mycobacterial Disease
Author: David E. Griffith
Publisher: Springer
Total Pages: 515
Release: 2018-10-05
Genre: Medical
ISBN: 3319934732
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This book is a comprehensive and authoritative source on nontuberculous mycobacterial (NTM) pathogens and diseases and their appropriate management, with a focus on lung disease. NTM diseases, especially lung diseases, are increasing in prevalence in the U.S. and internationally with concomitant growing interest in a broad section of the medical community. Often merely included in coverage of tuberculosis, many aspects of NTM organisms and diseases are actually very different than TB. These differences are not intuitive or trivial and frequently result in suboptimal management of NTM patients. This book addresses these gaps in the literature with chapters on microbiology, pathophysiology, epidemiology, the various diseases that can stem from NTM, and their particular management. There is also coverage on prevention and NTM as a public health problem. For pulmonologists and infectious disease physicians, this is the definitive resource on nontuberculous mycobacteria.

Mycobacterium Ulcerans Disease: Diagnosis and Treatment

Mycobacterium Ulcerans Disease: Diagnosis and Treatment
Author: Gerald Fuller
Publisher: American Medical Publishers
Total Pages: 246
Release: 2021-11-16
Genre: Medical
ISBN: 9781639272280
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Mycobacterium ulcerans disease, also known as Buruli ulcer, is an infection caused by the Mycobacterium ulcerans bacteria. This species of bacteria is found in various aquatic environments, predominantly in areas with a humid and hot climate. It can infect humans and some other animals such as rats and cattle, causing the development of painless open wounds. Myobacterium ulcerans disease affects the skin and bones. It can lead to permanent disfiguration and long-term disability. It does not spread from one person to another. This book includes some of the vital pieces of work being conducted across the world, on the Mycobacterium ulcerans disease, and its diagnosis and treatment. The various studies that are constantly contributing towards advancement in this field are examined in detail. This book will help the readers in keeping pace with the rapid changes in this field.

Bacterial Diseases

Bacterial Diseases
Author: Muhammad Imran Qadir
Publisher: Bentham Science Publishers
Total Pages: 212
Release: 2020-09-08
Genre: Medical
ISBN: 9811473749
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Bacterial Diseases provides readers an overview of a broad variety of bacterial infections. Chapters cover the description of specific disease and its causative agent, followed by information about symptoms, diagnosis and clinical management. This easy-to-read resource is a suitable introductory textbook for pharmacy, medical, and dental students, as well as M Phil, and Ph.D. candidates for Pharmacology, Botany, Zoology, Microbiology, Pharmacy, Biotechnology and allied health science programs. Readers interested in a simple clinical summary of bacterial diseases can also benefit from the information provided. Key Features: - Coverage of a broad spectrum of bacterial infections over 41 topical chapters - Easy-to-read presentation which provides a basic description of diseases covered to clinical diagnosis and management - Emphasis on the route of infection - References for further reading