Muscle Biopsy
Author | : Victor Dubowitz |
Publisher | : Bailliere Tindall Limited |
Total Pages | : 746 |
Release | : 1985 |
Genre | : Medical |
ISBN | : |
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Author | : Victor Dubowitz |
Publisher | : Bailliere Tindall Limited |
Total Pages | : 746 |
Release | : 1985 |
Genre | : Medical |
ISBN | : |
Author | : Balan Louis Gaspar |
Publisher | : Springer |
Total Pages | : 299 |
Release | : 2018-09-24 |
Genre | : Medical |
ISBN | : 9811314624 |
This book covers all aspects of basic, essential, recent advances and controversies in myopathology. The major emphasis is on diagnostic myopathology of muscular dystrophies, inflammatory myopathies, mitochondrial myopathies, metabolic myopathies, congenital myopathies, myopathies of miscellaneous etiology, neurogenic and neuromuscular junction disorders, the goal being to broaden readers’ understanding of individual disease subgroups. The book also contains all the essential details needed to establish a neuromuscular lab, making it especially relevant for laboratory technical staff and research scholars.
Author | : George Karpati |
Publisher | : Cambridge University Press |
Total Pages | : 800 |
Release | : 2001-07-12 |
Genre | : Medical |
ISBN | : 9780521650625 |
Rewritten and redesigned, this remains the one essential text on the diseases of skeletal muscle.
Author | : Victor Dubowitz |
Publisher | : Elsevier Health Sciences |
Total Pages | : 549 |
Release | : 2020-05-28 |
Genre | : Medical |
ISBN | : 0702078581 |
For more than 45 years, Muscle Biopsy: A Practical Approach has offered, comprehensive, clinically-focused coverage of the acquisition, interpretation, and assessment of muscle biopsies – an area often only lightly covered in pathology texts. Taking an integrated approach that includes clinical, genetic, biochemical, and pathological features, the 5th Edition covers the full range of muscle disease in both adults and children. This highly illustrated, easy-to-use volume helps you navigate this challenging area, bridging the gap between clinical syndromes/disorders and their underlying pathologies. Fully updated 5th edition of this internationally acclaimed classic in muscle pathology. Written by internationally recognized world leaders in the field of muscle pathology. Comprehensive coverage of histology, histochemistry, immunocytochemistry and electron microscopy in parallel with clinical and genetic advances. Lavishly illustrated with over 600 full colour images. Fully updated literature review. Comprehensive update on the rapidly expanding field of neuromuscular disorders. 4th edition Highly Commended in Pathology category of the prestigious 2014 BMA Medical Book Awards.
Author | : Michael Swash |
Publisher | : Springer |
Total Pages | : 216 |
Release | : 2013-12-20 |
Genre | : Medical |
ISBN | : 1489934022 |
During the last 20 years the development of enzyme histochemical techniques has contributed greatly to knowledge of muscle pathology. However, these and other new methods, such as electron microscopy and immunocytochemistry, have only relatively recently become gener ally available for routine use in histopathology. Muscle biopsy is a long-established technique in clinical practice, having been introduced by Duchenne in 1868 (Arch. Gen. Med. , 11, 5-179). However, the needle method used by Duchenne was not generally adopted, although Shank and Hoagland described a similar technique in 1943 (Science, 98, 592). During this time muscle biopsies required a surgical procedure and this was a considerable disincentive to their use. It was not until Bergstrom (1962; Scand. J. Clin. Lab. Invest. , 14, Suppl. 68) and Edwards (1971; Lancet, ii, 593--6) developed a simple biopsy needle suitable for muscle work in connection with exercise physiology that the advantages of needle muscle biopsies came to be appreciated. Since then, muscle biopsies have become a relatively minor procedure. This has led to the increasing use of muscle biopsy in clinical practice, both for diagnosis and for assessing progress in repeated biopsies during the course of a disorder and its treatment. The full range of enzyme histochemical and ultrastructural histological techniques can be applied to these small biopsies and many of the older histological staining methods can also be used. This book is intended to serve as a practical guide in muscle pathology, particularly for histopathologists, and for those in training.
Author | : Stirling Carpenter |
Publisher | : New York : Churchill Livingstone |
Total Pages | : 812 |
Release | : 1984 |
Genre | : Medical |
ISBN | : |
This book has been described as the bible of muscle disease, from both a scientific and a clinical point of view. It is a comprehensive work that explains and illustrates in detail all pathological reactions of skeletal muscles that occur in human disease. The microscopic changes are illustrated by histochemistry, immunocytochemistry, resin histology, and electron microscopy. The pathological findings are correlated with the clinical picture whenever possible. The interpretation of the findings is scientifically based. To facilitate this process, the fundamentals of normal histology and biology of the muscle cell are also covered.The book has been thoroughly revised and expanded for this Second Edition to provide up-to-date coverage of the relevant molecular biology and molecular genetics, as well as extensive references. It has been well organized and richly illustrated by the authors, who have been at the forefront of muscle pathology and neuromuscular research for 35 years. This practical reference work is intended for neuropathologists, neurologists, and general pathologists who look at muscle biopsies. It will also serve as an introduction to muscle disease for neurology and pathology residents.
Author | : Marinos C. Dalakas |
Publisher | : Butterworth-Heinemann |
Total Pages | : 362 |
Release | : 2013-10-22 |
Genre | : Health & Fitness |
ISBN | : 1483163040 |
Polymyositis and Dermatomyositis provides extensive information regarding Polymyositis and Dermatomyositis (PM/DM), which is described as a heterogeneous disease complex. This book is divided into four sections: Part I (Clinical Features) covers the classification of PM/DM, details of the clinical presentation, and the disease's association with the other connective tissue disorders and malignancies. Part II (Etiology and Mechanisms) covers advances in the immunopathology and viral etiology of PM/DM along with a frequently recognized entity: inclusion body myositis. Part III (Diagnosis and Treatment) covers the histologic, muscle enzyme histochemical, electron microscopic, and resin histology features of PM/DM along with those electromyographic features that could help make a more accurate diagnosis. Part IV (Overview) summarizes the issues that may not have been clear and highlights differing and unsettled views or present available data. This text is directed to clinicians in private practice or in academic institutions concerned with PM/DM patients, including neurologists, rheumatologists, pediatricians, dermatologists, physiatrists, and neuromuscular investigators. This book is intended as well for neuromuscular pathologists who interpret muscle biopsy specimens and electromyographers who perform EMG studies to help determine the clinical diagnosis. Researchers in immunology and immunopathology of neuromuscular diseases will find discussions in this book invaluable.
Author | : Lan Zhou |
Publisher | : Springer Nature |
Total Pages | : 408 |
Release | : 2019-10-24 |
Genre | : Medical |
ISBN | : 3030256820 |
This book provides a practical guide to the field of neuromuscular pathology including muscle, peripheral nerve, and skin biopsies with biopsy interpretation. Divided into three parts, the book begins with introductory chapters that review muscle, nerve, and skin biopsy indications and procedures, normal muscle and nerve histology, and common muscle and nerve pathology. The 28 myopathy case chapters in Part 2 and 11 neuropathy case chapters in Part 3 illustrate the clinical and pathological features of many neuromuscular diseases, demonstrate the indications and utilities of biopsies, discuss clinical and pathological differential diagnosis, update the individual disease management, and summarize pertinent clinical and pathology pearls for each case. A Case-Based Guide to Neuromuscular Pathology will function as an indispensable reference for neurologists and pathologists looking to understand the utility of muscle, nerve, and skin biopsies. This book will also aid neurology residents, neuromuscular fellows and neuropathology fellows in preparing for questions related to the muscle and nerve pathology in their in-service and board exams.
Author | : Victor Dubowitz |
Publisher | : Elsevier Health Sciences |
Total Pages | : 585 |
Release | : 2013-04-01 |
Genre | : Medical |
ISBN | : 0702043400 |
2014 BMA Medical Book Awards Highly Commended in Pathology category! Muscle Biopsy: A Practical Approach gives you all of the unparalleled guidance necessary to effectively interpret and diagnose muscle biopsy specimens for the full range of diseases in both adults and children. Authored by Dr. Victor Dubowitz, internationally renowned figure in the field of muscle disease, this medical reference book takes an integrated approach to diagnosis and assessment of muscle biopsies that includes clinical, genetic, biochemical, and pathological features. It's the comprehensive, up-to-date coverage you need to evaluate muscle disorders with confidence "Overall, this is a well written and comprehensive textbook of muscle pathology that will be of invaluable assistance to laboratories reporting muscle pathology" Reviewed by The Bulletin of The Royal College of Pathologists, Jan 2015 Bridge the gap between clinical syndromes/disorders and their underlying pathologies with the guidance of muscle disease expert, Dr. Victor Dubowitz, who skillfully guides you through the complexities of pathologic diagnoses and their implications for clinical treatment. Understand and apply expert techniques for obtaining a muscle biopsy, and familiarize yourself with the histochemical, histological, electron microscopical, and molecular appearance of normal muscle and the pathology of individual muscle disease. Read the entire contents and download all of the images online at Expert Consult. Apply all of the latest diagnostic techniques for neurodegenerative and genetic diseases with a brand-new chapter on myopathies associated with systemic disorders and aging, and use advanced techniques such as immunohistochemistry and immunoblotting to produce the most accurate diagnoses possible for a full range of muscle disorders. Stay current in practice with state-of-the-art coverage of genetic markers for individual conditions and antibodies used in immunocytochemical diagnosis. Understand the genetics of muscular dystrophies with absolute clarity through the use of brilliantly simple diagrams and tables, and compare your specimens to a wealth of superb color images capturing the full spectrum of muscle biopsy findings. Take advantage of international insights and fresh perspectives in muscle diseases and disorders from new author Dr. Anders Oldfors, from the Department of Pathology, University of Goteborg, Sweden.
Author | : Victor Dubowitz |
Publisher | : Elsevier Health Sciences |
Total Pages | : 627 |
Release | : 2007-01-01 |
Genre | : Medical |
ISBN | : 1416025936 |
In this book, Professor Victor Dubowitz manages to bridge the gap between clinical syndromes/disorders and their underlying pathologies. An internationally renowned figure in the field of muscle disease, Professor Dubowitz skillfully guides you through the complexities of pathologic diagnoses and their implications for clinical treatment. This reference describes the techniques of obtaining a muscle biopsy and examines the histochemical, histological, electron microscopical and molecular appearance of normal muscle and the pathology of individual muscle disease. Covers the entire range of diagnostic/investigative techniques, providing you with all of the necessary tools to formulate an accurate diagnosis. Offers a combination of clinical and pathological experience for a unique perspective on a complex and difficult area of diagnosis. Addresses the "knowledge explosion" over the last 10 years in the fields of molecular genetics and immunocytochemistry, including all of the latest clinically relevant investigative techniques. Focuses on diagnostic techniques and on the diagnostic interpretation of results, giving you a portable reference book and a bench book in a single volume. Presents all the latest techniques in molecular diagnosis and immunocytochemistry as they apply to individual disorders. Includes high-quality, full-color illustrations throughout the book. Incorporates tables, summary charts, and boxes to provide a user-friendly, accessible format.