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Molecular Biology of The Cell

Molecular Biology of The Cell
Author: Bruce Alberts
Publisher:
Total Pages: 0
Release: 2002
Genre: Cytology
ISBN: 9780815332183

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Microtubule Dynamics

Microtubule Dynamics
Author: Anne Straube
Publisher: Humana Press
Total Pages: 319
Release: 2017-04-30
Genre: Science
ISBN: 9781493961856

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Microtubules are at the heart of cellular self-organization, and their dynamic nature allows them to explore the intracellular space and mediate the transport of cargoes from the nucleus to the outer edges of the cell and back. In Microtubule Dynamics: Methods and Protocols, experts in the field provide an up-to-date collection of methods and approaches that are used to investigate microtubule dynamics in vitro and in cells. Beginning with the question of how to analyze microtubule dynamics, the volume continues with detailed descriptions of how to isolate tubulin from different sources and with different posttranslational modifications, methods used to study microtubule dynamics and microtubule interactions in vitro, techniques to investigate the ultrastructure of microtubules and associated proteins, assays to study microtubule nucleation, turnover, and force production in cells, as well as approaches to isolate novel microtubule-associated proteins and their interacting proteins. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Definitive and practical, Microtubule Dynamics: Methods and Protocols provides the key protocols needed by novices and experts on how to perform a broad range of well-established and newly-emerging techniques in this vital field.


Motor Proteins and Molecular Motors

Motor Proteins and Molecular Motors
Author: Anatoly B. Kolomeisky
Publisher: CRC Press
Total Pages: 221
Release: 2015-05-21
Genre: Medical
ISBN: 1482224763

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A Unified Microscopic Approach to Analyzing Complex Processes in Molecular MotorsMotor Proteins and Molecular Motors explores the mechanisms of cellular functioning associated with several specific enzymatic molecules called motor proteins. Motor proteins, also known as molecular motors, play important roles in living systems by supporting cellular


Particulate Flows

Particulate Flows
Author: Donald A. Drew
Publisher: Springer Science & Business Media
Total Pages: 155
Release: 2012-12-06
Genre: Mathematics
ISBN: 1468471090

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This IMA Volume in Mathematics and its Applications PARTICULATE FLOWS: PROCESSING AND RHEOLOGY is based on the proceedings of a very successful one-week workshop with the same title, which was an integral part of the 1995-1996 IMA program on "Mathematical Methods in Materials Science." We would like to thank Donald A. Drew, Daniel D. Joseph, and Stephen L. Passman for their excellent work as organizers of the meeting. We also take this opportunity to thank the National Science Foun dation (NSF), the Army Research Office (ARO) and the Office of Naval Research (ONR), whose financial support made the workshop possible. A vner Friedman Robert Gulliver v PREFACE The workshop on Particulate Flows: Processing and Rheology was held January 8-12, 1996 at the Institute for Mathematics and its Applications on the University of Minnesota Twin Cities campus as part of the 1995- 96 Program on Mathematical Methods in Materials Science. There were about forty participants, and some lively discussions, in spite of the fact that bad weather on the east coast kept some participants from attending, and caused scheduling changes throughout the workshop. Heterogeneous materials can behave strangely, even in simple flow sit uations. For example, a mixture of solid particles in a liquid can exhibit behavior that seems solid-like or fluid-like, and attempting to measure the "viscosity" of such a mixture leads to contradictions and "unrepeatable" experiments. Even so, such materials are commonly used in manufacturing and processing.


Mechanics of Motor Proteins and the Cytoskeleton

Mechanics of Motor Proteins and the Cytoskeleton
Author: Jonathon Howard
Publisher: Sinauer
Total Pages: 0
Release: 2005-12-06
Genre: Science
ISBN: 9780878933334

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Mechanics of Motor Proteins and the Cytoskeleton provides a physical foundation for molecular mechanics. Part I explains how small particles like proteins respond to mechanical, thermal, and chemical forces, Part II focuses on cytoskeletal filaments, and Part III focuses on motor proteins. The treatments are unified in the respect that they are organized around principles rather than proteins: chapters are centred on topics such as structure, chemistry, and mechanics, and different filaments or motors are discussed together.


Mechanical Splitting of Microtubules Into Protofilament Bundles by Surface-bound Kinesin-1

Mechanical Splitting of Microtubules Into Protofilament Bundles by Surface-bound Kinesin-1
Author:
Publisher:
Total Pages:
Release: 2016
Genre:
ISBN:

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The fundamental biophysics of gliding microtubule (MT) motility by surface-tethered kinesin-1 motor proteins has been widely studied, as well as applied to capture and transport analytes in bioanalytical microdevices. In these systems, phenomena such as molecular wear and fracture into shorter MTs have been reported due the mechanical forces applied on the MT during transport. In the present work, we show that MTs can be split longitudinally into protofilament bundles (PFBs) by the work performed by surface-bound kinesin motors. We examine the properties of these PFBs using several techniques (e.g., fluorescence microscopy, SEM, AFM), and show that the PFBs continue to be mobile on the surface and display very high curvature compared to MT. Further, higher surface density of kinesin motors and shorter kinesin-surface tethers promote PFB formation, whereas modifying MT with GMPCPP or higher paclitaxel concentrations did not affect PFB formation.


The Fokker-Planck Equation

The Fokker-Planck Equation
Author: Hannes Risken
Publisher: Springer Science & Business Media
Total Pages: 486
Release: 2012-12-06
Genre: Mathematics
ISBN: 3642615449

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This is the first textbook to include the matrix continued-fraction method, which is very effective in dealing with simple Fokker-Planck equations having two variables. Other methods covered are the simulation method, the eigen-function expansion, numerical integration, and the variational method. Each solution is applied to the statistics of a simple laser model and to Brownian motion in potentials. The whole is rounded off with a supplement containing a short review of new material together with some recent references. This new study edition will prove to be very useful for graduate students in physics, chemical physics, and electrical engineering, as well as for research workers in these fields.


Molecular Motor Proteins—Advances in Research and Application: 2013 Edition

Molecular Motor Proteins—Advances in Research and Application: 2013 Edition
Author:
Publisher: ScholarlyEditions
Total Pages: 38
Release: 2013-06-21
Genre: Science
ISBN: 148167773X

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Molecular Motor Proteins—Advances in Research and Application: 2013 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about ZZZAdditional Research in a compact format. The editors have built Molecular Motor Proteins—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Molecular Motor Proteins—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.