Mosaic Of Autoimmunity PDF Download
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| Author | : Carlo Perricone |
| Publisher | : Academic Press |
| Total Pages | : 728 |
| Release | : 2019-02-15 |
| Genre | : Medical |
| ISBN | : 012814307X |
Download Mosaic of Autoimmunity Book in PDF, ePub and Kindle
The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis. Highlights the concept of the mosaic of autoimmune manifestations Includes new visions on unsuspected molecules Provides updated knowledge to physicians helping patients with autoimmune diseases Presents thorough, up-to-date information on specific diseases, along with clinical applications
| Author | : Yehuda Shoenfeld |
| Publisher | : Elsevier Science Limited |
| Total Pages | : 523 |
| Release | : 1989 |
| Genre | : Medical |
| ISBN | : 9780444811844 |
Download The Mosaic of Autoimmunity Book in PDF, ePub and Kindle
This book comprehensively sets out the common aetiopathogenetic mechanisms shared by many, apparently diverse, diseases of the immune system. Unlike most other texts it does not emphasise the differences between autoimmune diseases, but establishes their many common links including hormonal effects, dietary and immunogenetic influences, complement deficiencies and environmental factors. Special attention is given to the effects of ageing and the relationship with malignancies. The scope of the book is very broad so as to cover the integration of the many diverse components which interact to cause autoimmunity, and it contains many 1988 and 1989 references and over 100 figures and tables, offering an attractive, up-to-date guide to modern concepts. It will greatly assist immunologists wishing to enter the field of autoimmunity, and will serve as an invaluable reference work for those already working in it.
| Author | : R.C. Kennedy |
| Publisher | : Elsevier |
| Total Pages | : 557 |
| Release | : 1997-11-19 |
| Genre | : Medical |
| ISBN | : 0080534430 |
Download Idiotypes in Medicine: Autoimmunity, Infection and Cancer Book in PDF, ePub and Kindle
This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.
| Author | : Yehuda Shoenfeld |
| Publisher | : John Wiley & Sons |
| Total Pages | : 394 |
| Release | : 2015-07-07 |
| Genre | : Science |
| ISBN | : 1118663438 |
Download Vaccines and Autoimmunity Book in PDF, ePub and Kindle
In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants – specifically aluminum in different vaccines – and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals. Vaccines and Autoimmunity is divided into three sections; the first contextualizes the role of adjuvants in the framework of autoimmunity, covering the mechanism of action of adjuvants, experimental models of adjuvant induced autoimmune diseases, infections as adjuvants, the Gulf War Syndrome, sick-building syndrome (SBS), safe vaccines, toll-like receptors, TLRS in vaccines, pesticides as adjuvants, oil as adjuvant, mercury, aluminum and autoimmunity. The following section reviews literature on vaccines that have induced autoimmune conditions such as MMR and HBV, among others. The final section covers diseases in which vaccines were known to be the solicitor – for instance, systemic lupus erythematosus – and whether it can be induced by vaccines for MMR, HBV, HCV, and others. Edited by leaders in the field, Vaccines and Autoimmunity is an invaluable resource for advanced students and researchers working in pathogenic and epidemiological studies.
| Author | : Yehuda Shoenfeld |
| Publisher | : |
| Total Pages | : 523 |
| Release | : 1989 |
| Genre | : Maladies auto-immunes |
| ISBN | : 9780444801623 |
Download The Mosaic of Autoimmunity Book in PDF, ePub and Kindle
| Author | : Yehuda Shoenfeld |
| Publisher | : Elsevier Publishing Company |
| Total Pages | : 556 |
| Release | : 1989 |
| Genre | : Health & Fitness |
| ISBN | : |
Download The Mosaic of Autoimmunity Book in PDF, ePub and Kindle
This book comprehensively sets out the common aetiopathogenetic mechanisms shared by many, apparently diverse, diseases of the immune system. Unlike most other texts it does not emphasise the differences between autoimmune diseases, but establishes their many common links including hormonal effects, dietary and immunogenetic influences, complement deficiencies and environmental factors. Special attention is given to the effects of ageing and the relationship with malignancies. The scope of the book is very broad so as to cover the integration of the many diverse components which interact to cause autoimmunity, and it contains many 1988 and 1989 references and over 100 figures and tables, offering an attractive, up-to-date guide to modern concepts. It will greatly assist immunologists wishing to enter the field of autoimmunity, and will serve as an invaluable reference work for those already working in it.
| Author | : Yehuda Shoenfeld |
| Publisher | : Newnes |
| Total Pages | : 917 |
| Release | : 2013-11-26 |
| Genre | : Medical |
| ISBN | : 0444593772 |
Download Autoantibodies Book in PDF, ePub and Kindle
Autoimmune diseases are characterized by the occurrence of antibodies reacting with self-constituents of the body. The fully updated third edition of Autoantibodies is an in-depth review of the main autoantibodies identified up to now, with particular emphasis on those that display a diagnostic or prognostic clinical value. The new edition covers recent scientific advances, diagnostic techniques, and therapeutic technologies. Each chapter is focused on a single family of autoantibodies. This important reference contains historical notes, definitions, origins and sources of antigens recognized genetic associations, mediated pathogenic mechanisms, methods of detection, as well as clinical utility (disease prevalence and association, diagnostic value, sensitivity and specificity, prognostic value). This is an ideal reference for anyone involved in the field of autoimmune diseases. Presents all known, important autoantibodies in a single source, focusing on the antibodies needed for autoimmune disorder diagnosis Includes clinical applications for each autoantibody along with general information Organized by disease and disorder type, by autoantibody family, and completely cross-referenced
| Author | : Yehuda Shoenfeld |
| Publisher | : |
| Total Pages | : 523 |
| Release | : 1989 |
| Genre | : |
| ISBN | : 9780444801623 |
Download The Mosaic of Autoimmunity Book in PDF, ePub and Kindle
| Author | : Yehuda Shoenfeld |
| Publisher | : Wiley-Blackwell |
| Total Pages | : 468 |
| Release | : 2007-08-06 |
| Genre | : Medical |
| ISBN | : |
Download Autoimmunity, Part C Book in PDF, ePub and Kindle
The incidence of autoimmune diseases is increasing worldwide, and the search for better management of these diseases and even for a cure is being pursued by scientists from many disciplines. Tools from the areas of genetics, neuorscience, cell biology, virology, and infectious disease are being applied to the problem and are yielding useful results. This is the third volume of a series of four on autoimmunity, and findings related to particular organs, organ systems, and diseases are presented. The focus in Part C is on autoimmunity and vessel pathology, the neurologic system, cancer, the GI tract, diabetes, the lung, and the heart. Autoimmunity, Part D completes the group of volumes and also presents research focusing on clinical manifestations of autoimmunity. See Parts A and B for basic research findings. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member
| Author | : Tomohiro Kurosaki |
| Publisher | : Springer |
| Total Pages | : 231 |
| Release | : 2015-12-26 |
| Genre | : Medical |
| ISBN | : 3319261339 |
Download B Cell Receptor Signaling Book in PDF, ePub and Kindle
This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.
