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Pathophysiology of Heart Disease

Pathophysiology of Heart Disease
Author: Naranjan S. Dhalla
Publisher: Springer Science & Business Media
Total Pages: 398
Release: 1987-02-28
Genre: Medical
ISBN: 9780898388640

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It is indeed ironical that in the absence of a complete knowledge of Pathophysiology, clinical cardiologists are left with no choice but to do the best they can to help the patient with the armamentarium of drugs at their disposal. But nothing could be further from truth than to treat the diagnosed end point of a disease process without a full understanding of its patho physiology. This point was eloquently made by Dr. Arnold Katz in his Presidential Address (Chapter 1) at the 8th Annual Meeting of the American Section of the International Society for Heart Research held in Winnipeg, Canada, July 8-11, 1986. This volume represents a part of the scientific proceedings of this Meeting. From a reading of this treatise it will become evident that discoveries of newer scientific facts as well as a better understanding of pathophysiology are continuously influencing/ improving our therapeutic approaches in modern medicine. In this book, latest biochemical, physiological and pharmacological findings on different experimental models such as Myocaridal hypertrophy, Hypertension and heart failure, Diabetes, Cardio myopathies and Cardiac function in shock are described by internationally recognised experts. Hopefully information presented here will provide another building block to the edifice of Science of Cardiology which we all are trying to create. Acknowledgements We are grateful to the following Agencies and Foundations for their generous financial support of the Symposium, which formed the basis of this book. A. Major Contributors: 1. Manitoba Heart Foundation 2. Sterling-Winthrop Research Institute 3. Squibb Canada, Inc.


Guy's Hospital Reports

Guy's Hospital Reports
Author:
Publisher:
Total Pages: 572
Release: 1883
Genre: Hospitals
ISBN:

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The Valley of Heart's Delight

The Valley of Heart's Delight
Author: Michael S. Malone
Publisher: John Wiley & Sons
Total Pages: 312
Release: 2002-07-10
Genre: Business & Economics
ISBN: 9780471201915

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The history of the heart of the high-tech world Mike Malone is a journalist who has covered Silicon Valley for nearly twenty years. This book combines the best of his work from a variety of renowned publications to offer a true-to-life glimpse of the world's most important industrial community. These stories form a picture of a place at the center of cultural, economic, and technological advancement and the people who live there, from dot.com millionaires to everyday working people just trying to get by. Not confined to its present technological significance, the book looks at the rich history of the Valley and the future that awaits it. Meticulously researched and broad in scope, The Valley of Heart's Delight is the definitive biography of a place of massive cultural and political significance. Michael S. Malone (Palo Alta, CA) joined the San Jose Mercury News in 1980 as the nation's first daily high-tech reporter. His writings on Silicon Valley earned him two Pulitzer Prize nominations. He has also written for the New York Times, the Boston Globe, the Dallas Morning News, the Wall Street Journal, and the Los Angeles Times. He is currently the Editor at Large for ASAP.


The Stressed Heart

The Stressed Heart
Author: Marianne J. Legato
Publisher: Springer Science & Business Media
Total Pages: 347
Release: 2012-12-06
Genre: Medical
ISBN: 1461320410

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The Stressed Heart is truly unique in concept and will provide an eXCItmg adventure to the reader no matter what his or her field of expertise and interest. The title, although quite appropriate, does not adequately indicate the range of topics considered or the rational interrelationships among them. Indeed, perhaps the most important point to be learned from the book is that a serious consideration of the response of the heart to mechanical overload, ischemia, or excessive humoral stimuli must include evaluation of each of the topics in the table of contents. The heart responds to stress through alterations in both structure and function. How these changes are brought about is the subject of the initial chapters. These consider first the normal regulation of gene expression in the heart, the rapid response to mechanical overload that leads to both quantitative and qualitative changes in the contractile proteins, and our current understand ing of the signals that might be elicited by stress and alter gene expression. One chapter emphasizes the fact that, regardless of the nature of the stress, the common denominator is a discrepancy between energy requirements and expenditure. The central role of cellular acidosis in initiating the sequence of responses to stress and the possible roles of peptide regulators of transcription and protein regulators of translation are considered in detail.


Medical Subject Headings

Medical Subject Headings
Author: National Library of Medicine (U.S.)
Publisher:
Total Pages: 1208
Release: 1993
Genre: Index medicus
ISBN:

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Heart Development

Heart Development
Author: Richard P. Harvey
Publisher: Gulf Professional Publishing
Total Pages: 574
Release: 1999
Genre: Medical
ISBN: 9780123298607

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Contributors. -- Preface. -- C. Seidman, Introduction. -- I. Origins and Early Morphogenesis: -- P.P.L. Tam and G.C. Schoenwolf, Cardiac Fate Maps: Lineage Allocation, Morphogenetic Movement, and Cell Commitment. -- T. Mikawa, Cardiac Lineages. -- II. Cardiac Induction: -- T.J. Mohun and L.M. Leong, Heart Formation and the Heart Field in Amphibian Embryos. -- T.M. Schultheiss and A.B. Lassar, Vertebrate Heart Induction. -- III. Genetic Dissection of Heart Development: -- R. Bodmer and M. Frasch, Genetic Determination in Drosophilia Heart Development. -- J. Alexander and D.Y.R. Stainier, Mutations Affecting Cardiac Development in Zebrafish. -- R.P. Harvey, C. Biben, and D.A. Elliott, Transcriptional Control and Pattern Formation in the Developing Vertebrate Heart: Studies on NK-2 Class Homeodomain Factors. -- B.L. Black and E.N. Olson, Control of Cardiac Development by the Family of MEF2 Transcription Factors. -- D. Srivastava, Segmental Regulation of Cardiac Development by the Basic He ...


Cardiovascular Therapeutics

Cardiovascular Therapeutics
Author: Elliott M. Antman
Publisher: Elsevier Health Sciences
Total Pages: 973
Release: 2007-01-22
Genre: Medical
ISBN: 143771093X

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This companion to Braunwald's Heart Disease equips you with all of today's most effective therapeutic guidelines and management solutions for the full range of heart disease patients. It reflects the most recent standards for drug management as well as the latest in new technologies. Reorganized to mirror your changing practice, each cardiovascular-problem-based section offers a chapter on pharmacologic treatment (with a minimum of pathophysiology)...a chapter on catheter-based or minimally invasive interventions...and a discussion of surgical options. You'll also find a brand-new chapter on gene therapy and stem cell therapy, plus new chapters on many other rapidly developing areas of practice. The result is an outstanding single-volume source for state-of-the-art, clinically oriented guidance on both common and unusual areas of cardiovascular treatment. Facilitates the decision-making process clinicians face when choosing among various cardiovascular therapeutic options. covers the latest concepts in pathophysiology, evaluation, and management of patients with cardiovascular disorders Addresses pharmacological, interventional, and surgical management approaches for each type of cardiovascular disease, putting advice on the full range of therapeutic options at your disposal. Keeps you current with brand-new chapters on gene therapy and stem cell therapy * unstable and chronic stable angina * management of unstable angina and non-ST-elevation myocardial infarction * devices for heart failure and arrhythmias * prevention of ischemic disease * the regulatory approval process for new cardiovascular drugs and devices * and more. Delivers a fully revised section on "Heart Failure" that explores cardiac resynchronization therapy, surgical interventions, ambulatory management, hospital management, and cardiac transplantation and circulatory support devices. Offers a completely updated section on "Other Cardiovascular Conditions" that addresses issues such as pharmacologic treatment of cardiovascular disease during pregnancy * care for adults with congenital heart disease * treatment of primary pulmonary hypertension * prevention and treatment of infective endocarditis * treatment of pericardial disease * and rehabilitation of the patient with cardiovascular disease. Reflects a new emphasis on the role of diet and exercise in the management of cardiovascular problems in conformity with ACC/AHA/ESC guidelines.