Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Mononuclear Phagocytes In The Central Nervous System PDF full book. Access full book title Mononuclear Phagocytes In The Central Nervous System.
| Author | : M. Oehmichen |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 277 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 3642463851 |
| Author | : Manfred Oehmichen |
| Publisher | : Springer |
| Total Pages | : 173 |
| Release | : 1978-01-01 |
| Genre | : Central nervous system |
| ISBN | : 9780387089584 |
| Author | : M. Oehmichen |
| Publisher | : Springer |
| Total Pages | : 196 |
| Release | : 1978-10-01 |
| Genre | : Medical |
| ISBN | : 9783540089582 |
A number of years ago Prof. J. Peiffer (Tiibingen/FRG) asked whether cerebros- nal fluid cells originate in blood cells. With this question, the first seeds were sown for the research which resulted in this book. The original question was eventually ex panded to whether extravascular hematogenous cells are present in the nervous sys tem. In the course of my research this question became more and more concentrated on the demonstration of monocyte derivatives (i.e., mononuclear phagocytes) within the nervous system. While these questions are certainly not new, they regularly crop up when micro glia are to be classified, particularly progressive microglia. Three extensive surveys were published during the past few years, all of which arrived at different conclusions (Cammermeyer, 1970b; Vaughn and Skoff, 1972; Fujita and Kitamura, 1976). In ad dition to progressive microglia, other active phagocytes were observed which I refer to as "perivascular cells," "free subarachnoidal cells," and "epiplexus cells." These cells were seldom described in the literature, and then predominantly in another context. A pre sentation based on the hypothesis that the cell types of the central nervous system have po tentially identical kinetics and functional potency has not been published.
| Author | : Manfred Oehmichen |
| Publisher | : |
| Total Pages | : |
| Release | : 1978 |
| Genre | : |
| ISBN | : |
| Author | : Perry |
| Publisher | : Springer |
| Total Pages | : 136 |
| Release | : 1994 |
| Genre | : Medical |
| ISBN | : |
The interface between the immune and nervous systems is an increasingly important area of scientific research. This book is an up-to-date review of research conducted on the main cell of the immune system (macrophage) and its relationship with neuronal cells.
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 993 |
| Release | : 2013-05-06 |
| Genre | : Science |
| ISBN | : 0123973481 |
The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 1 offers 48 high level articles devoted mainly to patterning and cell type specification in the developing central and peripheral nervous systems. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop Features leading experts in various subfields as Section Editors and article Authors All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship Volume 1 sections include coverage of mechanisms which: control regional specification, regulate proliferation of neuronal progenitors and control differentiation and survival of specific neuronal subtypes, and controlling development of non-neural cells
| Author | : Jeffrey K. Harrison |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 412 |
| Release | : 2007-11-17 |
| Genre | : Medical |
| ISBN | : 1597450200 |
This volume, new to The Receptors series, focuses on several areas, including the birth, maturation, and structure of Chemokines; Neutrophil, Dendritic, and Lymphocyte trafficking; and Chemokine Receptors in diseases such as AIDs and lung cancer. In particular the book contains cutting-edge information ranging from basic molecular and cellular mechanisms to physiological and pathological roles of chemokines.
| Author | : Glaxo Professor of Cellular Immunology Siamon Gordon |
| Publisher | : |
| Total Pages | : 510 |
| Release | : 2003-07-10 |
| Genre | : |
| ISBN | : 9783642557439 |
During the past decade, the rapid growth of molecular and cellular knowledge of macrophages, as a specialized host defense and homeostatic system, has begun to offer attractive targets for therapeutic intervention. Macrophages play a central role in a wide range of disease processes, from genetically determined lysosomal storage diseases, to acute sepsis, chronic inflammation and repair, tissue injury and cell death. Under- or overactivity of macrophage clearance, immune effector functions and responses to metabolic abnormalities contribute to common disorders such as autoimmunity, atherosclerosis, Alzheimer s disease and major infections including AIDS and Tuberculosis. Whilst the goals of therapeutic intervention based on improved understanding of macrophage functions and their contribution to pathogenesis may seem self evident, there are considerable difficulties in producing useful new agents. The present volume covers a range of subjects and provides opportunities for a more focused macrophage-targeted approach. The individual chapters review selected topics briefly, to place cellular processes and molecular targets in perspective. Overall, the volume should provide a broad sample of the state of the art. Useful reviews and references in the literature are cited within individual chapters.
| Author | : Alessandro Michelucci |
| Publisher | : Frontiers Media SA |
| Total Pages | : 108 |
| Release | : 2018-10-05 |
| Genre | : |
| ISBN | : 2889456013 |
Microglia are essential for the development and function of the adult brain. Their ontogeny, together with the absence of turnover from the periphery and the singular environment of the central nervous system (CNS), make microglia a unique cell population compared to other tissue-macrophages. The unique properties and functions of microglial cells, such as their role in synaptic pruning or the exceptional capacity to scan the brain parenchyma and rapidly react to its perturbations, have emerged in recent years. In the coming years, understanding how microglia acquire and maintain their unique profiles in order to fulfil distinct tasks in the healthy CNS and how these are altered in disease, will be essential to develop strategies to diagnose or treat CNS disorders with an immunological component. This Research Topic covers several aspects of microglial biology, ranging from their origin and the functional role of microglia during development and lifespan, their molecular properties compared with other brain and peripheral immune cells to microglial phenotypes and functional states in neurodegenerative diseases and brain tumours. In conclusion, the present Research Topic provides a comprehensive overview of our current understanding of several cellular and molecular mechanisms that make microglia a unique immune cell population within the healthy CNS as well as under inflammatory, neurodegenerative and tumorigenic processes.
| Author | : Norman Saunders |
| Publisher | : CRC Press |
| Total Pages | : 354 |
| Release | : 2003-09-02 |
| Genre | : Medical |
| ISBN | : 0203304489 |
Degeneration and Regeneration in the Nervous System brings together an international team of contributors to produce a series of critical reviews appraising key papers in the field. The pace of research on brain and spinal cord injury quickened considerably in the last ten years and there is much that is new and important that is covered in this book. However, there is still a long way to go before our knowledge will explain fully why the central nervous system has such a limited capacity for regeneration, and before experimental solutions can be applied to the patient. With emphasis on actual and therapeutic importance of the work reviewed, Degeneration and Regeneration in the Nervous System is a useful overview for graduate students, their teachers and researchers working in this field.
