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| Author | : T. Schroeder |
| Publisher | : |
| Total Pages | : 10 |
| Release | : 1992 |
| Genre | : Monoclonal antibodies |
| ISBN | : |
| Author | : Robert Ettenger |
| Publisher | : |
| Total Pages | : 10 |
| Release | : 1992 |
| Genre | : |
| ISBN | : |
| Author | : |
| Publisher | : |
| Total Pages | : |
| Release | : 1992 |
| Genre | : |
| ISBN | : |
| Author | : William J. Burlingham |
| Publisher | : CRC Press |
| Total Pages | : 154 |
| Release | : 1991-12-18 |
| Genre | : Medical |
| ISBN | : 9780849368219 |
Critical Analysis of Monoclonal Antibody Therapy in Transplantation provides a critical analysis of monoclonal antibody therapies in transplantation. The book presents diverse approaches to monoclonal antibody therapy in transplantation and addresses some of the serious obstacles that remain both in understanding these mechanisms and in successfully applying them in clinical situations. The background and rationale for OKT3 therapy are examined and an extensive clinical experience with OKT3 induction therapy in cardiac transplantation is reviewed. The book also examines the background and rationale for the use of anti-TcR (??), anti-IL-2R, and anti-LFA-1 monoclonal antibodies in clinical transplantations. Other topics include the use of monclonal antibodies to CD4 and CD8 for the induction of adult transplantation tolerance in rodents and the possibilities for applying anti-idiotypical strategies that have proven useful in autoimmunity models to transplant recipients. Researchers and basic scientists involved in this field will find the book a fascinating and useful resource for their investigations.
| Author | : Lucienne Chatenoud |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 198 |
| Release | : 2013-11-22 |
| Genre | : Medical |
| ISBN | : 3662221950 |
Experimental and clinical evidence presented in this book illustrates that antibodies expressing different specificities can be very effective in preventing or reversing established transplant rejection. Moreover, the data leads us to hope that the use of these new therapeutic agents may allow the induction of specific tolerance to transplant alloantigens which is the only means to avoid the major risks of sustained immunosuppression, namely an increased susceptibility to infection and tumor development. In this volume the editors combine contributions dealing with very practical aspects of the clinical use of monoclonal antibodies with a more general discussion on the developments one may foresee in the near future.
| Author | : Juliet C. Gray |
| Publisher | : Springer |
| Total Pages | : 300 |
| Release | : 2017-11-21 |
| Genre | : Medical |
| ISBN | : 3319434861 |
This book provides a comprehensive overview of current immunotherapy strategies, and how these may be applicable to childhood cancers. The first part of the book reviews how the immune system recognizes cancer, and the various escape mechanisms allowing tumour growth. The importance of the tumor microenvironment and the challenges this may present to achieving effective immunotherapy are discussed. Monoclonal antibodies, cellular, cytokine and vaccine therapies are all comprehensively reviewed, with particular focus on their potential application to pediatric cancers. Practical aspects of delivering such therapies to children, likely toxicities and potential biomarkers are considered. Finally, consideration is given to how, in the longer term, such therapies may be combined with conventional therapies such as chemotherapy and radiotherapy. Edited by two distinguished pediatric oncologists with a collection of chapters from the most authoritative experts in cancer immunotherapy, this is an indispensable volume for pediatric oncologists and physicians working in childhood cancer care.
| Author | : Richard N. Fine |
| Publisher | : Wiley-Blackwell |
| Total Pages | : 500 |
| Release | : 2000-12-07 |
| Genre | : Medical |
| ISBN | : 9788716122735 |
To provide a more cohesive approach to the teaching of pediatric transplantation in various subspecialties, the council of IPTA has initiated the compilation of this book. In organizing the structure of the text, the Editors have recognized that there is a central core of information that is common to all clinical transplantation. Grouped together in the first two sections of the book, this core is intended to provide information about the immune system, rejection and tolerance, immunosuppressives and infection. Organ specific sections are structured in common format designed to cover transplantation, while maintaining the unique needs of the organ specialty.
| Author | : Lucienne Chatenoud |
| Publisher | : |
| Total Pages | : 208 |
| Release | : 2014-09-01 |
| Genre | : |
| ISBN | : 9783662221969 |
| Author | : William J. Steinbach |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 288 |
| Release | : 2020-02-05 |
| Genre | : Medical |
| ISBN | : 0323641997 |
As the number and types of pediatric transplants increase and the complexity of chemotherapy regimens continues to evolve, there is a greater need for authoritative guidance, clinically actionable strategies, and easy-to-find information in the challenging area of immunocompromised pediatric patients. Pediatric Transplant and Oncology Infectious Diseases offers up-to-date, targeted coverage of this complex field, compiled by world-renowned editors and authors into one convenient volume. Covers the must-know principles for diagnosing and managing opportunistic infections in immunocompromised populations and detailed aspects of their care – information not specifically covered in pediatric infectious disease textbooks or pediatric oncology books. Features algorithms in every chapter that provide visual, accessible overviews of treatment protocols. Discusses key topics such as microbiome implications in transplantation and oncology, antimicrobial resistant Gram-negative bacteria, EBV-associated post-transplant lymphoproliferative disorders, and many others. Offers well-referenced, evidence-based content throughout, with targeted suggested readings provided.
| Author | : Bruce Kaplan |
| Publisher | : John Wiley & Sons |
| Total Pages | : 485 |
| Release | : 2012-05-07 |
| Genre | : Medical |
| ISBN | : 1405182717 |
This comprehensive reference source will benefit all transplant specialists working with pharmacologic and biologic agents that modulate the immune system. Compiled by a team of world-renowned editors and contributors covering the fields of transplantation, nephrology, pharmacology, and immunology, the book covers all anti-rejection drugs according to a set template and includes the efficacy of each for specific diseases.
