Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Monoclonal Antibodies Diagnostic And Therapeutic Use In Tumor And Transplantation PDF full book. Access full book title Monoclonal Antibodies Diagnostic And Therapeutic Use In Tumor And Transplantation.
| Author | : Satya N. Chatterjee |
| Publisher | : |
| Total Pages | : 175 |
| Release | : 1985 |
| Genre | : |
| ISBN | : 9780884165118 |
| Author | : Satya N. Chatterjee |
| Publisher | : |
| Total Pages | : 200 |
| Release | : 1985 |
| Genre | : Medical |
| ISBN | : |
| Author | : Andrew J.T. George |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 471 |
| Release | : 2008-02-02 |
| Genre | : Medical |
| ISBN | : 1592590764 |
Soon after the first description of monoclonal antibodies in 1976, there was enormous interest in the clinical application of antibodies, especially in the context of cancer. Antibodies appeared to offer the “magic bullet” that would allow the specific destruction of neoplastic cells. H- ever, many years’ effort resulted in very few cases of successful immu- therapy with antibodies. As a result there was a major backlash against antibody therapy, and the field lost a considerable amount of popularity. Fashion, in science as well as in other things, tends to be cyclical. Antibody-based therapy is once again attracting scientists and clinicians. There are several reasons for the renewed optimism; certainly the expe- ence of the last two decades has provided a wealth of information about problems associated with antibody therapy, and possible solutions to these problems. Recombinant antibody engineering has rejuvenated the field, allowing both the modification of antibodies to improve their in vivo pr- erties and the isolation of novel antibody molecules by such techniques as phage display. The results of recent clinical trials have demonstrated unequivocally the benefit of antibody therapy in a number of settings, and, finally, more careful consideration has been taken of the types of disease best treated using this approach.
| Author | : Satya N. Chatterjee |
| Publisher | : |
| Total Pages | : 13 |
| Release | : 1985 |
| Genre | : Immunoglobulins |
| ISBN | : |
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 288 |
| Release | : 2019-07-13 |
| Genre | : Medical |
| ISBN | : 0128173173 |
Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series
| Author | : Lucienne Chatenoud |
| Publisher | : |
| Total Pages | : 208 |
| Release | : 2014-09-01 |
| Genre | : |
| ISBN | : 9783662221969 |
| Author | : Yuti Chernajovsky |
| Publisher | : Springer |
| Total Pages | : 380 |
| Release | : 2007-11-22 |
| Genre | : Medical |
| ISBN | : 9783540732587 |
This essential work, edited by two researchers at London’s famous Queen Mary’s medical school targets one of the most important areas in medical development today. These days, antibody therapeutics are the treatment of choice for several autoimmune and oncological conditions. They are, indeed, becoming the molecules of choice for further combination therapies and cell engineering. In this timely work, a slew of expert in the field of drug development summarize all the current developments and clinical successes.
| Author | : Robert W Maitta |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 380 |
| Release | : 2019-08-27 |
| Genre | : Medical |
| ISBN | : 0323675107 |
Immunological Concepts in Transfusion Medicine provides a thorough discussion of the immune aspects of blood component transfusion, with in-depth information on the intricacies of immune responses to blood components and the immune processes that may be initiated in response to blood exposure. Written to increase knowledge and awareness of immune challenges such as alloimmunization and transfusion-related acute lung injury, this title bridges current basic scientific discoveries and the potential effects seen in blood recipients. Complies the knowledge and expertise of Dr. Robert Maitta, an expert in immune responses and antibody function/structure studies. Helps clinicians in the daily practice of caring for patients in need of transfusion support, as well as physicians in training when considering utilizing blood transfusions in a limited scope or in the setting of massive transfusion. Includes an immunology primer as an introduction to in-depth chapters covering allergic immune reactions to blood components, transfusion-related immunomodulation, fetal and neonatal alloimmune thrombocytopenia and neonatal neuthropenia, complications of haploidentical and mismatched HSC transplantation, chimeric antibody receptor therapies, and much more. Consolidates today’s available information on this timely topic into a single, convenient resource.
| Author | : National Library of Medicine (U.S.) |
| Publisher | : |
| Total Pages | : 1712 |
| Release | : |
| Genre | : Medicine |
| ISBN | : |
First multi-year cumulation covers six years: 1965-70.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 74 |
| Release | : 1999-05-06 |
| Genre | : Medical |
| ISBN | : 0309173051 |
The American Anti-Vivisection Society (AAVS) petitioned the National Institutes of Health (NIH) on April 23, 1997, to prohibit the use of animals in the production of mAb. On September 18, 1997, NIH declined to prohibit the use of mice in mAb production, stating that "the ascites method of mAb production is scientifically appropriate for some research projects and cannot be replaced." On March 26, 1998, AAVS submitted a second petition, stating that "NIH failed to provide valid scientific reasons for not supporting a proposed ban." The office of the NIH director asked the National Research Council to conduct a study of methods of producing mAb. In response to that request, the Research Council appointed the Committee on Methods of Producing Monoclonal Antibodies, to act on behalf of the Institute for Laboratory Animal Research of the Commission on Life Sciences, to conduct the study. The 11 expert members of the committee had extensive experience in biomedical research, laboratory animal medicine, animal welfare, pain research, and patient advocacy (Appendix B). The committee was asked to determine whether there was a scientific necessity for the mouse ascites method; if so, whether the method caused pain or distress; and, if so, what could be done to minimize the pain or distress. The committee was also asked to comment on available in vitro methods; to suggest what acceptable scientific rationale, if any, there was for using the mouse ascites method; and to identify regulatory requirements for the continued use of the mouse ascites method. The committee held an open data-gathering meeting during which its members summarized data bearing on those questions. A 1-day workshop (Appendix A) was attended by 34 participants, 14 of whom made formal presentations. A second meeting was held to finalize the report. The present report was written on the basis of information in the literature and information presented at the meeting and the workshop.
