Molecular Population Genetics PDF Download
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Author | : Matthew William Hahn |
Publisher | : Sinauer Associates, Incorporated |
Total Pages | : 334 |
Release | : 2018 |
Genre | : Molecular genetics |
ISBN | : 9780878939657 |
Download Molecular Population Genetics Book in PDF, ePub and Kindle
Published by Sinauer Associates, an imprint of Oxford University Press. Provides descriptions of the methods and tools used in molecular population genetics, which has combined advances in molecular biology and genomics with mathematical and empirical findings to uncover the history of natural selection and demographic shifts in many organisms.
Author | : Asher D. Cutter |
Publisher | : Oxford University Press, USA |
Total Pages | : 266 |
Release | : 2019 |
Genre | : Science |
ISBN | : 0198838948 |
Download A Primer of Molecular Population Genetics Book in PDF, ePub and Kindle
What are the genomic signatures of adaptations in DNA? How often does natural selection dictate changes to DNA? How does the ebb and flow in the abundance of individuals over time get marked onto chromosomes to record genetic history? Molecular population genetics seeks to answer such questions by explaining genetic variation and molecular evolution from micro-evolutionary principles. It provides a way to learn about how evolution works and how it shapes species by incorporating molecular details of DNA as the heritable material. It enables us to understand the logic of how mutations originate, change in abundance in populations, and become fixed as DNA sequence divergence between species. With the revolutionary advances in genomic data acquisition, understanding molecular population genetics is now a fundamental requirement for today's life scientists. These concepts apply in analysis of personal genomics, genome-wide association studies, landscape and conservation genetics, forensics, molecular anthropology, and selection scans. This book introduces, in an accessible way, the bare essentials of the theory and practice of molecular population genetics.
Author | : Asher D. Cutter |
Publisher | : Oxford University Press |
Total Pages | : 266 |
Release | : 2019-06-06 |
Genre | : Science |
ISBN | : 0192575546 |
Download A Primer of Molecular Population Genetics Book in PDF, ePub and Kindle
What are the genomic signatures of adaptations in DNA? How often does natural selection dictate changes to DNA? How does the ebb and flow in the abundance of individuals over time get marked onto chromosomes to record genetic history? Molecular population genetics seeks to answer such questions by explaining genetic variation and molecular evolution from micro-evolutionary principles. It provides a way to learn about how evolution works and how it shapes species by incorporating molecular details of DNA as the heritable material. It enables us to understand the logic of how mutations originate, change in abundance in populations, and become fixed as DNA sequence divergence between species. With the revolutionary advances in genomic data acquisition, understanding molecular population genetics is now a fundamental requirement for today's life scientists. These concepts apply in analysis of personal genomics, genome-wide association studies, landscape and conservation genetics, forensics, molecular anthropology, and selection scans. This book introduces, in an accessible way, the bare essentials of the theory and practice of molecular population genetics.
Author | : Motoo Kimura |
Publisher | : University of Chicago Press |
Total Pages | : 736 |
Release | : 1994 |
Genre | : Science |
ISBN | : 9780226435633 |
Download Population Genetics, Molecular Evolution, and the Neutral Theory Book in PDF, ePub and Kindle
One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution—the neutral theory—and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change. Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and random drift account for variations at the level of DNA and amino acids, Kimura advanced a theory of evolutionary change that was strongly challenged at first and that eventually earned the respect and interest of evolutionary biologists throughout the world. This volume includes the seminal papers on the neutral theory, as well as many others that cover such topics as population structure, variable selection intensity, the genetics of quantitative characters, inbreeding systems, and reversibility of changes by random drift. Background essays by Naoyuki Takahata examine Kimura's work in relation to its effects and recent developments in each area.
Author | : Manuel Ruiz-Garcia |
Publisher | : Nova Science Publishers |
Total Pages | : 0 |
Release | : 2013 |
Genre | : Carnivora |
ISBN | : 9781624170713 |
Download Molecular Population Genetics, Evolutionary Biology, and Biological Conservation of Neotropical Carnivores Book in PDF, ePub and Kindle
The neotropical ecoregion consisting of South America, Central America, Southern Mexico, the Caribbean Islands, and Southern Florida, has long been considered an area rich in mammalian diversity and one that contains some of the worlds iconic carnivores. Unfortunately, due to human population pressures, many neotropical areas and the mammals within them are increasingly at risk. This book contains contributions from 60 of the world's leading scientists in the area of neotropical carnivores.
Author | : Masatoshi Nei |
Publisher | : Columbia University Press |
Total Pages | : 526 |
Release | : 1987 |
Genre | : Computers |
ISBN | : 9780231063210 |
Download Molecular Evolutionary Genetics Book in PDF, ePub and Kindle
-- "The Scientist"
Author | : John H. Gillespie |
Publisher | : Oxford University Press |
Total Pages | : 351 |
Release | : 1994-05-26 |
Genre | : Science |
ISBN | : 0195357744 |
Download The Causes of Molecular Evolution Book in PDF, ePub and Kindle
This work provides a unified theory that addresses the important problem of the origin and maintenance of genetic variation in natural populations. With modern molecular techniques, variation is found in all species, sometimes at astonishingly high levels. Yet, despite these observations, the forces that maintain variation within and between species have been difficult subjects of study. Because they act very weakly and operate over vast time scales, scientists must rely on indirect inferences and speculative mathematical models. However, despite these obstacles, many advances have been made. The author's research in molecular genetics, evolution, and bio-mathematics has enabled him to draw on this work, and present a coherent and valuable view of the field. The book is divided into three parts. The first consists of three chapters on protein evolution, DNA evolution, and molecular mechanisms. This section reviews the experimental observations on genetic variation. The second part gives a unified treatment of the mathematical theory of selection in a fluctuating environment. The final two chapters combine the earlier assessments in a treatment of the scientific status of two competing theories for the maintenance of genetic variation. Steeped in the enormous advances population genetics has made over the past 25 years, this book has proven highly popular among human geneticists, biologists, evolutionary theorists, and bio-mathematicians.
Author | : Daniel L. Hartl |
Publisher | : Sinauer Associates Incorporated |
Total Pages | : 652 |
Release | : 2007 |
Genre | : Science |
ISBN | : 9780878933082 |
Download Principles of Population Genetics Book in PDF, ePub and Kindle
This edition provides a balanced presentation of theory and observation. It introduces the principles of genetics and statistics that are relevant to population studies, and examines the forces affecting genetic variation from the molecular to the organismic level.
Author | : Matthew B. Hamilton |
Publisher | : John Wiley & Sons |
Total Pages | : 658 |
Release | : 2011-09-23 |
Genre | : Science |
ISBN | : 1444362453 |
Download Population Genetics Book in PDF, ePub and Kindle
This book aims to make population genetics approachable, logical and easily understood. To achieve these goals, the book’s design emphasizes well explained introductions to key principles and predictions. These are augmented with case studies as well as illustrations along with introductions to classical hypotheses and debates. Pedagogical features in the text include: Interact boxes that guide readers step-by-step through computer simulations using public domain software. Math boxes that fully explain mathematical derivations. Methods boxes that give insight into the use of actual genetic data. Numerous Problem boxes are integrated into the text to reinforce concepts as they are encountered. Dedicated website at www.wiley.com/go/hamiltongenetics This text also offers a highly accessible introduction to coalescent theory, the major conceptual advance in population genetics of the last two decades.
Author | : Yuri Kartavtsev |
Publisher | : CRC Press |
Total Pages | : 0 |
Release | : 2015-08-06 |
Genre | : Science |
ISBN | : 9781498701600 |
Download Molecular Evolution and Population Genetics for Marine Biologists Book in PDF, ePub and Kindle
Research in modern experimental and theoretical population genetics has been strengthened by advances in molecular techniques for the analysis of genetic variability. The evolutionary relationships of organisms may be investigated by comparing DNA sequences. This book covers chapters on population genetics, DNA polymorphism, genetic homeostasis, and biochemical genetics, plus a chapter on phylogenetic tree construction. In addition, each chapter contains training materials with numerical examples.