Molecular Pharmacology PDF Download
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Author | : John Dickenson |
Publisher | : John Wiley & Sons |
Total Pages | : 675 |
Release | : 2012-11-30 |
Genre | : Medical |
ISBN | : 1118451953 |
Download Molecular Pharmacology Book in PDF, ePub and Kindle
This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trend towards molecular based drug design, derived from a detailed understanding of chemical responses in the body. Drugs are then tailored to fit a treatment profile, rather than the traditional method of ‘trial and error’ drug discovery which focuses on testing chemicals on animals or cell cultures and matching their effects to treatments. Providing an invaluable resource for advanced under-graduate and MSc/PhD students, new researchers to the field and practitioners for continuing professional development, Molecular Pharmacology explores; recent advances and developments in the four major human drug target families (G-protein coupled receptors, ion channels, nuclear receptors and transporters), cloning of drug targets, transgenic animal technology, gene therapy, pharmacogenomics and looks at the role of calcium in the cell. Current - focuses on cutting edge techniques and approaches, including new methods to quantify biological activities in different systems and ways to interpret and understand pharmacological data. Cutting Edge - highlights advances in pharmacogenomics and explores how an individual’s genetic makeup influences their response to therapeutic drugs and the potential for harmful side effects. Applied - includes numerous, real-world examples and a detailed case-study based chapter which looks at current and possible future treatment strategies for cystic fibrosis. This case study considers the relative merits of both drug therapy for specific classes of mutation and gene therapy to correct the underlying defect. Accessible - contains a comprehensive glossary, suggestions for further reading at the end of each chapter and an associated website that provides a complete set of figures from within the book.
Author | : Stefan Offermanns |
Publisher | : Springer Science & Business Media |
Total Pages | : 1515 |
Release | : 2008-08-14 |
Genre | : Medical |
ISBN | : 3540389164 |
Download Encyclopedia of Molecular Pharmacology Book in PDF, ePub and Kindle
An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.
Author | : Francesco Clementi |
Publisher | : John Wiley & Sons |
Total Pages | : 784 |
Release | : 2015-07-01 |
Genre | : Medical |
ISBN | : 1118768590 |
Download General and Molecular Pharmacology Book in PDF, ePub and Kindle
With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecular perspective, with particular attention to the mechanisms of drug action – the fundamental basis for proper clinical use- without neglecting clinical application, toxicology and pharmacokinetics. • Covers cell and molecular pharmacology, bringing together current research on regulation of drug targets, at a level appropriate for advanced undergrad and graduate students • Discusses the relevance of pharmacokinetics and drug development for the clinical application of drugs • Presents material from the perspective of drug targets and interaction, the theoretical basis of drug action analysis, and drug properties • Focuses on structure-function relationships of drug targets – informing about their biochemical and physiologic functions and experimental and clinical pathways for drug discovery and development • Has a companion website that offers a host of resources: short additional chapters about methodology, topics at the forefront of research, and all figures and tables from the book
Author | : Amteshwar Singh Jaggi |
Publisher | : |
Total Pages | : 384 |
Release | : 2021-02 |
Genre | : Medical |
ISBN | : 9789389974348 |
Download Cellular and Molecular Pharmacology Book in PDF, ePub and Kindle
Author | : Bryan L. Roth |
Publisher | : Springer Science & Business Media |
Total Pages | : 628 |
Release | : 2008-08-17 |
Genre | : Medical |
ISBN | : 1597450804 |
Download The Serotonin Receptors Book in PDF, ePub and Kindle
A comprehensive, state-of-the-art review of our current understanding of the molecular and structural biology of 5-HT receptors and their potential use for drug discovery. The authors describe the anatomical, cellular, and subcellular distribution of 5-HT receptors and demonstrate a powerful approach to elucidating their physiological role using knockout mice in which the 5-HT receptors were deleted. They also review our understanding of the physiological role(s) of 5-HT receptors based mainly on studies performed in genetically engineered mice. Highlights include discussions of the behavioral phenotypes of 5-HT receptor knockout animals, the molecular biology and pharmacology of 5-HT receptors, and insights into the complexity of 5-HT receptor signal transduction.
Author | : J. B. Stenlake |
Publisher | : A&C Black |
Total Pages | : 336 |
Release | : 1979-01-01 |
Genre | : Medical |
ISBN | : 9780485111729 |
Download Foundations of Molecular Pharmacology Book in PDF, ePub and Kindle
Author | : Angel Catala |
Publisher | : BoD – Books on Demand |
Total Pages | : 168 |
Release | : 2020-12-16 |
Genre | : Medical |
ISBN | : 1839629312 |
Download Molecular Pharmacology Book in PDF, ePub and Kindle
This book concentrates on recent developments related to the application of original structural biology, biochemistry, biophysics, physiology, genetics, and molecular biology as well as basic pharmacological problems that offer mechanistic insights that are generally significant for the field of pharmacology. Written by experts, chapters cover such topics as drug transport mechanisms and drug–receptor complexes. This volume offers up-to-date, expert reviews of the fast-moving field of molecular pharmacology.
Author | : Mithun Rudrapal |
Publisher | : Elsevier |
Total Pages | : 582 |
Release | : 2024-06-28 |
Genre | : Medical |
ISBN | : 0443160147 |
Download Biochemical and Molecular Pharmacology in Drug Discovery Book in PDF, ePub and Kindle
Biochemical and Molecular Pharmacology in Drug Discovery comprises fundamental biochemical and molecular aspects of drug discovery and basic understanding of modern drug discovery approaches along with certain key topics related to molecular pharmacology of drugs and therapeutics. Molecular pharmacology has gained significant momentum among researchers, scientists, and academicians because of its increasing interest in drug discovery research across the globe. Molecular pharmacology involves a fundamental understanding of drug actions at the molecular level with the help of several tools and techniques of biochemical and molecular biology. It explains the phenomena of drug-target interactions considering different biochemical systems and cellular strategies. With the advent of technologies, current advances and research trends move toward molecular and/or target-based drug design and discovery. Through this book, readers will be able to gain skills and knowledge with a thorough understanding of the subject of biochemical and molecular pharmacology, in a comprehensive and systematic manner with special reference to recent advances in drug discovery research. Highlights the fundamentals of biochemical and molecular aspects, with reference to drug discovery research Depicts modern drug discovery approaches such as reverse pharmacology, drug repositioning, and CADD in the context of current research updates Summarizes recent developments in the molecular pharmacology of novel drugs/ therapeutic molecules
Author | : Francesco Clementi |
Publisher | : John Wiley & Sons |
Total Pages | : 784 |
Release | : 2015-08-10 |
Genre | : Medical |
ISBN | : 1118768574 |
Download General and Molecular Pharmacology Book in PDF, ePub and Kindle
With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecular perspective, with particular attention to the mechanisms of drug action – the fundamental basis for proper clinical use- without neglecting clinical application, toxicology and pharmacokinetics. • Covers cell and molecular pharmacology, bringing together current research on regulation of drug targets, at a level appropriate for advanced undergrad and graduate students • Discusses the relevance of pharmacokinetics and drug development for the clinical application of drugs • Presents material from the perspective of drug targets and interaction, the theoretical basis of drug action analysis, and drug properties • Focuses on structure-function relationships of drug targets – informing about their biochemical and physiologic functions and experimental and clinical pathways for drug discovery and development • Has a companion website that offers a host of resources: short additional chapters about methodology, topics at the forefront of research, and all figures and tables from the book
Author | : Stefan Offermanns |
Publisher | : |
Total Pages | : 1152 |
Release | : 2004 |
Genre | : Medical |
ISBN | : |
Download Encyclopedic Reference of Molecular Pharmacology Book in PDF, ePub and Kindle
Presents current information on the molecular mechanisms of drug action. Provides 159 essays describing groups of drugs and drug targets. Several essays deal with general principles of pharmacology, such as drug tolerance, drug addiction, or drug metabolism.