Molecular Oncology Underlying Mechanisms And Translational Advancements PDF Download
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Author | : Ammad Ahmad Farooqi |
Publisher | : Springer |
Total Pages | : 302 |
Release | : 2017-03-29 |
Genre | : Medical |
ISBN | : 3319530828 |
Download Molecular Oncology: Underlying Mechanisms and Translational Advancements Book in PDF, ePub and Kindle
Cancer is a multifaceted and genomically complex disease and data obtained through high throughput technologies has provided near complete resolution of the landscape of how genomic, genetic and epigenetic mutations in cancerous cells effectively influence homeostasis of signaling networks within these cells, between cancerous cells, tumor microenvironment and at the organ level. Increasingly sophisticated information has helped us in developing a better understanding of the underlying mechanisms of cancer, and it is now known that intra-tumor genetic heterogeneity, cellular plasticity, dysregulation of spatio-temporally controlled signaling cascades, and loss of apoptosis are contributory in cancer development, progression and the development of resistance against different therapeutics. It is becoming progressively more understandable that earlier detection of pre-existing or emerging resistance against different therapeutics may prove to be helpful in personalizing the use of targeted cancer therapy. Despite the fact that there is a continuously increasing list of books, being guest edited by researchers, books on the subject are often composed of invited reviews without proper sequence and continuity and designed for a particular readership. This book progressively shifts and guides the readers from basic underlying mechanisms to translational approaches to treat cancer.
Author | : Fabrizio d'Adda di Fagagna |
Publisher | : Springer Science & Business Media |
Total Pages | : 274 |
Release | : 2007-07-18 |
Genre | : Medical |
ISBN | : 0387691162 |
Download Advances in Molecular Oncology Book in PDF, ePub and Kindle
Proceedings of the 2nd Annual IFOM-IEO Meeting on Cancer. This is a new meeting, it has about 200 attendees from Australia, Austria, Belgium, Brazil, Canada, England, France, Germany, Greece, Ireland, Italy, Japan, Netherlands, Spain, Sweden, Switzerland, and the USA. The 2nd IFOM-IEO international meeting on cancer will provide a forum in which the world’s leading cancer researchers and young scientists will discuss the latest advances in molecular oncology. The impact of recent breakthroughs in basic research and of emerging technologies on molecular medicine in cancer will be highlighted.
Author | : Miguel H. Bronchud |
Publisher | : Springer Science & Business Media |
Total Pages | : 429 |
Release | : 2008-03-16 |
Genre | : Medical |
ISBN | : 1597454702 |
Download Principles of Molecular Oncology Book in PDF, ePub and Kindle
Drawing on years of significant advances and developments, the editors of this third edition have thoroughly updated the highly praised first and second editions and added new chapters to reflect the knowledge emerging from research on genomics, proteomics, chemoprevention strategies, pharmacogenomics, new molecular targets, therapeutic monoclonal antibodies, and innovative cytotoxic and cytostatic small molecular-weight molecules.
Author | : Javier Camacho |
Publisher | : Bentham Science Publishers |
Total Pages | : 237 |
Release | : 2012-02-07 |
Genre | : Medical |
ISBN | : 1608050165 |
Download Molecular Oncology Principles and Recent Advances Book in PDF, ePub and Kindle
"Cancer is one of the major causes of death worldwide. Despite hundreds of clinical trials currently in progress for cancer patients, the success rate is still very low. Understanding the molecular aspects of cancer development, the discovery of new molecu"
Author | : Stefania Staibano |
Publisher | : Springer |
Total Pages | : 296 |
Release | : 2013-11-27 |
Genre | : Medical |
ISBN | : 9789400771505 |
Download Prostate Cancer: Shifting from Morphology to Biology Book in PDF, ePub and Kindle
The aim of this book will be to contribute to the education of a new generation of experts in urology, molecular biology, pathology and oncology, offering them sufficient knowledge in basic and translational research to be fluency in the web of interacting networks playing a role in prostate cancer development, progression, metastasis and drug-resistance.The volume will cover the latest innovative researches in prostate cancer, with particular emphasis to the state-of-the-art analysis technologies that are essential for the accurate identification of molecular targets for disease diagnosis, molecular mechanisms of tumorigenesis, markers for susceptibility, molecular-based prognostic prevision, characterization of biomarkers of drug efficacy and drug resistance, validation of new therapeutics and diagnostics. Current advancements on the intersecting data concerning transcriptomes, proteomes, the molecular techniques referred as "omes", will be reported and discussed.
Author | : Sapna Malviya |
Publisher | : CRC Press |
Total Pages | : 294 |
Release | : 2023-10-03 |
Genre | : Health & Fitness |
ISBN | : 1000923134 |
Download Medicinal Plants and Cancer Chemoprevention Book in PDF, ePub and Kindle
Cancer is the second leading cause of death globally. Medicinal Plants and Cancer Chemoprevention provides information on the use of various herbal plants used as anticancer agents. It discusses the traditional system of medicine and focuses on plant-derived compounds for cancer therapy with integrated approaches. Chapters present information on various medicinal plants that covers background and history, ethnomedical considerations, morphology, phytochemistry, and pharmacological properties. The book presents a scientific investigation on medicinal plants in managing cancer, reported mechanisms of action as anticancer activity, as well as covering the toxicological aspects of certain plants. KEY FEATURES: · Details information on plant-derived compounds for cancer therapy. · Features information on methods of extraction and isolation of various phytoconstituents responsible for anticancer activity. · Discusses herbal formulations and alternative approaches used for the management and treatment of cancer. · Demonstrates the importance of alternative approaches including yoga, acupuncture, and dietary supplements to be effective in the management of cancer. This book is helpful to botanists, researchers and practitioners in alternative and complementary medicine, and the herbal medicine research community.
Author | : Alexzander A. A. Asea |
Publisher | : Springer Nature |
Total Pages | : 307 |
Release | : 2019-10-30 |
Genre | : Science |
ISBN | : 3030242854 |
Download Heat Shock Proteins in Neuroscience Book in PDF, ePub and Kindle
The book Heat Shock Proteins in Neuroscience provides the most comprehensive review on contemporary knowledge on the role of HSP in signaling pathways relevant to a number of diseases. Using an integrative approach, the contributors provide a synopsis of novel mechanisms, signal transduction pathways. To enhance the ease of reading and comprehension, this book has been subdivided into various section including; Section I, reviews current progress on our understanding of Neurological Aspects of HSP; Section II, focuses on Aspects of HSP in Neurodegenerative Diseases and Disorders, Section III, emphasizes the importance of HSP in Multiple Sclerosis; Section IV, reviews critical Aspects of HSP in Alzheimer’s Disease and Section V, gives a comprehensive update of the Development of HSP-Based Therapies for Neurological Disorders. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for starters and professionals in the fields of Neurology and Neurosciences, Translational Medicine, Clinical Research, Human Physiology, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
Author | : Giulia Pasello |
Publisher | : Frontiers Media SA |
Total Pages | : 163 |
Release | : 2022-03-28 |
Genre | : Medical |
ISBN | : 2889748189 |
Download Understanding the Interplay Between the Tumor Immune Microenvironment and Genetic Alterations in Thoracic Malignancies Book in PDF, ePub and Kindle
Author | : Erika Ruiz-Garcia |
Publisher | : Springer Nature |
Total Pages | : 171 |
Release | : 2019-11-11 |
Genre | : Science |
ISBN | : 3030241009 |
Download Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics Book in PDF, ePub and Kindle
Being a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. On the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient’s specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and SNPs, and even more, taking into account the inmume system, the metabolism and maybe in the next future also the microbiome.
Author | : Jeffrey Stuart Ross |
Publisher | : Jones & Bartlett Learning |
Total Pages | : 642 |
Release | : 2005 |
Genre | : Medical |
ISBN | : 9780763748104 |
Download Molecular Oncology of Breast Cancer Book in PDF, ePub and Kindle
The first comprehensive reference to focus on the molecular development and treatment of the disease, Molecular Oncology of Breast Cancer provides authoritative information across the spectrum of modern breast cancer research and clinical care. Edited by two world-class experts in cancer pathology, drug development, and patient management, with contributions from over 50 experts, this ground-breaking text describes the genes, proteins, and biologic pathways that are being evaluated today and will be tested in the future to derive the molecular signature of each newly diagnosed breast cancer. For the first time, readers can now obtain, in a single volume, up-to-date information on how molecular-based tests are being used to identify predisposition, provide earliest detection, decide classification based on genetic fingerprint and predict therapy-specific outcomes. MOBC includes unique chapters on functional imaging and the impact of targeted therapies on the FDA approval process. This book gives readers vital, up-to-date information on important molecular discoveries that affect the everyday management of the breast cancer patient.