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Molecular Imaging

Molecular Imaging
Author: Brian D. Ross
Publisher: Academic Press
Total Pages: 1872
Release: 2021-08-03
Genre: Science
ISBN: 0128163879
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The detection and measurement of the dynamic regulation and interactions of cells and proteins within the living cell are critical to the understanding of cellular biology and pathophysiology. The multidisciplinary field of molecular imaging of living subjects continues to expand with dramatic advances in chemistry, molecular biology, therapeutics, engineering, medical physics and biomedical applications. Molecular Imaging: Principles and Practice, Volumes 1 and 2, Second Edition provides the first point of entry for physicians, scientists, and practitioners. This authoritative reference book provides a comprehensible overview along with in-depth presentation of molecular imaging concepts, technologies and applications making it the foremost source for both established and new investigators, collaborators, students and anyone interested in this exciting and important field. The most authoritative and comprehensive resource available in the molecular-imaging field, written by over 170 of the leading scientists from around the world who have evaluated and summarized the most important methods, principles, technologies and data Concepts illustrated with over 600 color figures and molecular-imaging examples Chapters/topics include, artificial intelligence and machine learning, use of online social media, virtual and augmented reality, optogenetics, FDA regulatory process of imaging agents and devices, emerging instrumentation, MR elastography, MR fingerprinting, operational radiation safety, multiscale imaging and uses in drug development This edition is packed with innovative science, including theranostics, light sheet fluorescence microscopy, (LSFM), mass spectrometry imaging, combining in vitro and in vivo diagnostics, Raman imaging, along with molecular and functional imaging applications Valuable applications of molecular imaging in pediatrics, oncology, autoimmune, cardiovascular and CNS diseases are also presented This resource helps integrate diverse multidisciplinary concepts associated with molecular imaging to provide readers with an improved understanding of current and future applications

Molecular Imaging

Molecular Imaging
Author: Shankar Vallabhajosula
Publisher: Springer Science & Business Media
Total Pages: 379
Release: 2009-07-13
Genre: Medical
ISBN: 3540767355
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Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.

Molecular Imaging

Molecular Imaging
Author: Ralph Weissleder
Publisher: PMPH-USA
Total Pages: 1384
Release: 2010
Genre: Diagnostic imaging
ISBN: 9781607950059
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The field of molecular imaging of living subjects have evolved considerably and have seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: "Molecular Imaging technologies", "Chemistry", "Molecular Imaging in Cell and Molecular Biology", "Applications of Molecular Imaging", "Molecular Imaging in Drug Evaluation" with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.

Essentials of Nuclear Medicine and Molecular Imaging E-Book

Essentials of Nuclear Medicine and Molecular Imaging E-Book
Author: Fred A. Mettler
Publisher: Elsevier Health Sciences
Total Pages: 624
Release: 2018-08-17
Genre: Medical
ISBN: 0323567894
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Covering both the fundamentals and recent developments in this fast-changing field, Essentials of Nuclear Medicine and Molecular Imaging, 7th Edition, is a must-have resource for radiology residents, nuclear medicine residents and fellows, nuclear medicine specialists, and nuclear medicine technicians. Known for its clear and easily understood writing style, superb illustrations, and self-assessment features, this updated classic is an ideal reference for all diagnostic imaging and therapeutic patient care related to nuclear medicine, as well as an excellent review tool for certification or MOC preparation. Provides comprehensive, clear explanations of everything from principles of human physiology, pathology, physics, radioactivity, radiopharmaceuticals, radiation safety, and legal requirements to hot topics such as new brain and neuroendocrine tumor agents and hybrid imaging, including PET/MR and PET/CT. Covers the imaging of every body system, as well as inflammation, infection and tumor imaging; pearls and pitfalls for every chapter; and pediatric doses and guidelines in compliance with the Image Gently and Image Wisely programs. Features a separate self-assessment section on differential diagnoses, imaging procedures and artifacts, and safety issues with unknown cases, questions, answers, and explanations. Includes new images and illustrations, for a total of 430 high-quality, multi-modality examples throughout the text. Reflects recent advances in the field, including updated nuclear medicine imaging and therapy guidelines • Updated dosimetry values and effective doses for all radiopharmaceuticals with new values from the 2015 International Commission on Radiological Protection • Updated information regarding advances in brain imaging, including amyloid, dopamine transporter and dementia imaging • Inclusion of Ga-68 DOTA PET/CT for neuroendocrine tumors • Expanded information on correlative and hybrid imaging with SPECT/CT • New myocardial agents • and more. Contains extensive appendices including updated comprehensive imaging protocols for routine and hybrid imaging, pregnancy and breastfeeding guidelines, pediatric dosages, non-radioactive pharmaceuticals used in interventional and cardiac stress imaging, and radioactivity conversion tables.

Pediatric Nuclear Medicine

Pediatric Nuclear Medicine
Author: S. Ted Treves
Publisher: Springer Science & Business Media
Total Pages: 617
Release: 2013-04-17
Genre: Medical
ISBN: 1475742053
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The 3rd edition of this classic – considered the standard in the field - reflects the latest advances in PET, SPECT, and oncology. Updated to incorporate cutting-edge diagnostic techniques, it serves as a bedrock resource for physicians whose nuclear medicine practices include children and provides a vast amount of background material for residents in training. The new edition retains the fundamental standard of excellence that earned its predecessors such a distinguished reputation. It has been thoroughly updated to incorporate cutting-edge diagnostic techniques. Pediatric Nuclear Medicine/PET, Third Edition is an indispensable resource for physicians whose practices include children and provides a vast amount of background material for residents in training.

Molecular Imaging

Molecular Imaging
Author: Ammasi Periasamy
Publisher: Elsevier
Total Pages: 329
Release: 2011-04-28
Genre: Science
ISBN: 0080536875
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The detection and measurement of the dynamic interactions of proteins within the living cell are critical to our understanding of cell physiology and pathophysiology. With FRET microscopy and spectroscopy techniques, basic and clinical scientists can make such measurements at very high spatial and temporal resolution. But sources of background information about these tools are very limited, so this book fills an important gap. It covers both the basic concepts and theory behind the various FRET microscopy and spectroscopy techniques, and the practical aspects of using the techniques and analyzing the results. The critical tricks for obtaining a good FRET image and precisely quantitating the signals from living specimens at the nanomolecular level are explained. Valuable information about the preparation of biological samples used for FRET image analysis is also provided. The methods covered include different types of microscopy systems and detectors (wide-field, confocal, multi-photon) as well as specialized techniques such as photobleaching FRET, FLIM-FRET microscopy, spectral imaging FRET, single molecule FRET, and time and image correlation spectroscopy. Starting from the basics, the chapters guide readers through the choice of probes to be used for FRET experiments and the selection of the most suitable experimental approaches to address specific biological questions. Up-to-date, consistently organized, and well-illustrated, this unique book will be welcomed by all researchers who wish to use FRET microscopy and spectroscopy techniques.

Nuclear Medicine and Molecular Imaging: The Requisites E-Book

Nuclear Medicine and Molecular Imaging: The Requisites E-Book
Author: Janis P. O'Malley
Publisher: Elsevier Health Sciences
Total Pages: 522
Release: 2020-05-20
Genre: Medical
ISBN: 0323550746
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Now in its 5th Edition, this outstanding volume in the popular Requisites series thoroughly covers the fast-changing field of nuclear medicine and molecular imaging. Ideal for residency, clinical rotations, and board review, this compact and authoritative volume by Drs. Janis O'Malley and Harvey Ziessman covers the conceptual, factual, and interpretive information you need to know for success on exams and in clinical practice. NEW to this edition: More content on molecular imaging and the latest advances in clinical applications, including positron emission tomography (PET), SPECT/CT, PET/CT, and PET/MRI hybrid imaging. Inclusion of newly approved tracers such as Ga68 DOTA, F-18 amyloid, and F-18 PSMA. Expanded and integrated content on physics and non-interpretive aspects, including regulatory issues, radiation safety, and quality control. Up-to-date applications of nuclear medicine in the endocrine, skeletal, hepatobiliary, genitourinary, pulmonary, gastrointestinal, central nervous, and cardiac systems, as well as PET applications for oncology. In the outstanding Requisites tradition, the 5th Edition also: Summarizes key information with numerous outlines, tables, pearls, pitfalls, and frequently asked questions. Focuses on essentials to pass the certifying board exam and ensure accurate diagnoses in clinical practice. Helps you clearly visualize the findings you're likely to see in practice and on exams with nearly 200 full-color images.

Handbook of Nuclear Medicine and Molecular Imaging for Physicists

Handbook of Nuclear Medicine and Molecular Imaging for Physicists
Author: Michael Ljungberg
Publisher: CRC Press
Total Pages: 655
Release: 2022-01-24
Genre: Medical
ISBN: 0429952252
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This state-of-the-art handbook, the first in a series that provides medical physicists with a comprehensive overview into the field of nuclear medicine, is dedicated to instrumentation and imaging procedures in nuclear medicine. It provides a thorough treatment on the cutting-edge technologies being used within the field, in addition to touching upon the history of their use, their development, and looking ahead to future prospects. This text will be an invaluable resource for libraries, institutions, and clinical and academic medical physicists searching for a complete account of what defines nuclear medicine. The most comprehensive reference available providing a state-of-the-art overview of the field of nuclear medicine Edited by a leader in the field, with contributions from a team of experienced medical physicists Includes the latest practical research in the field, in addition to explaining fundamental theory and the field's history

Molecular Imaging in Oncology

Molecular Imaging in Oncology
Author: Martin G. Pomper
Publisher: CRC Press
Total Pages: 762
Release: 2008-10-13
Genre: Medical
ISBN: 1000654400
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With molecular imaging becoming one the fastest growing topics in medical schools, Informa Healthcare presents Molecular Imaging in Oncology, the first comprehensive reference on molecular imaging in oncology.Giving clinicians and researchers a greater understanding of the current field, this text covers:instrumentation and techniquescancer imaging

Molecular Imaging

Molecular Imaging
Author: Jie Tian
Publisher: Springer Science & Business Media
Total Pages: 707
Release: 2013-07-23
Genre: Science
ISBN: 3642343031
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"Molecular Imaging: Fundamentals and Applications" is a comprehensive monograph which describes not only the theory of the underlying algorithms and key technologies but also introduces a prototype system and its applications, bringing together theory, technology and applications. By explaining the basic concepts and principles of molecular imaging, imaging techniques, as well as research and applications in detail, the book provides both detailed theoretical background information and technical methods for researchers working in medical imaging and the life sciences. Clinical doctors and graduate students will also benefit from this book. Jie Tian is a professor at the Institute of Automation, Chinese Academy of Sciences, China.