Molecular Genetics Of Endometrial Carcinoma PDF Download
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| Author | : Lora Hedrick Ellenson |
| Publisher | : Springer |
| Total Pages | : 281 |
| Release | : 2016-12-01 |
| Genre | : Medical |
| ISBN | : 3319431390 |
Download Molecular Genetics of Endometrial Carcinoma Book in PDF, ePub and Kindle
This comprehensive text provides a much-needed review of a disease that is currently garnering the interest of molecular biologists, translational scientists, and clinicians. The volume includes emerging developments in the molecular genetics of endometrial carcinoma. In addition to covering the basic genetics of endometrial carcinoma, chapters also cover a wide range of signaling pathways implicated in endometrial carcinoma. A section of the book includes a number of genetically engineered mouse models, which contribute to understanding the role of various genetic alterations in the development and progression of endometrial carcinoma. These models also provide preclinical models for developing effective targeted therapeutic approaches. Endometrial carcinoma is the most common malignancy of the female genital tract in the United States and the number of cases continues to increase around the world. This book is a meant to serve as a resource for a wide range of scientists, from molecular geneticists to signal transduction biologists, as well as to both clinicians and scientists interested in developing targeted therapeutic approaches for women with endometrial carcinoma.
| Author | : Ellen Smid-Koopman |
| Publisher | : |
| Total Pages | : 177 |
| Release | : 2002 |
| Genre | : |
| ISBN | : 9789077017975 |
Download Endometrial Cancer Book in PDF, ePub and Kindle
| Author | : Bahman Saffari |
| Publisher | : |
| Total Pages | : 304 |
| Release | : 1998 |
| Genre | : |
| ISBN | : |
Download Molecular Genetic Alterations in Endometrial Cancer Book in PDF, ePub and Kindle
| Author | : Mansoor R. Mirza |
| Publisher | : Springer |
| Total Pages | : 324 |
| Release | : 2019-08-26 |
| Genre | : Medical |
| ISBN | : 3319645137 |
Download Management of Endometrial Cancer Book in PDF, ePub and Kindle
This practical reference book provides up-to-date, evidence-based multidisciplinary guidelines on the epidemiology, biology, diagnosis, and treatment of endometrial cancer. Individual chapters focus on topics such as hormonal interactions, cancer prevention, genetic classification and its clinical applications. Recent advances in diagnostic methods are described. The treatment-oriented chapters include coverage of the roles of lymphadenectomy and sentinel node dissection, surgical complications, radiation techniques, and chemotherapy in early-stage disease. Treatment options in advanced disease, including hormonal therapy and targeted therapy, are considered separately, as is the management of rare tumor types. The authors are international key opinion leaders. Summaries of the ESMO/ESGO/ESTRO guidelines on management are included. Each clinical chapter ends with a summary of recommendations with the level of evidence.
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| Total Pages | : |
| Release | : 1995 |
| Genre | : |
| ISBN | : |
Download הגדה של פסח Book in PDF, ePub and Kindle
| Author | : Michael T. Deavers |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 2018-08-30 |
| Genre | : Medical |
| ISBN | : 9783319862965 |
Download Precision Molecular Pathology of Uterine Cancer Book in PDF, ePub and Kindle
This text provides a comprehensive review for practicing pathologists to understand the molecular biology, diagnostics, and predictive markers and implications for therapy of uterine cancer. While molecular based therapeutic strategies for uterine cancer are not as well developed as for some other organ sites, these are the most common gynecologic malignancies and there have been many important recent developments that are discussed in this volume. Comprehensive chapters address essential information about endometrial carcinoma, uterine mesenchymal tumors, and cervical carcinoma and include the pathogenesis of carcinoma and discuss molecular based classification, biomarkers, therapy, prevention, and hereditary cancers of the uterus. Precision Molecular Pathology of Uterine Cancer is a unique and one of a kind resource for practicing pathologists, pathologists in training and gynecologists.
| Author | : |
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| Total Pages | : 0 |
| Release | : 2003 |
| Genre | : |
| ISBN | : |
Download Molecular Biology and Prevention of Endometrial Cancer Book in PDF, ePub and Kindle
To increase our understanding of the molecular aberrations associated with endometrial carcinogenesis and the biologic mechanisms underlying the protective effect of oral contraceptive therapy. Methods: 1) Oligonucleotide microarray analysis was performed on a panel of endometrial cancers. 2) A subset of adenocarcinoma cases from the International DES Registry was analyzed for MSI and the poor quality of the DNA from many of these cases prohibited an adequate analysis of the entire set. The cases are currently being evaluated for PTEN expression. 3) We are in the process of analyzing the endometrium from cymologous macaques that were exposed to long term progestins as part of the three year randomized controlled trial. 4) A clinical trial comparing progestin versus placebo is underway that will facilitate investigation of the effects of progestin exposure on the endometrial lining Results: 1) Different histological types of endometrial cancer have unique genomic expression patterns. 2) Endometrioid endometrial cancers with microsatellite instability have a genomic expression pattern that is different from those microsatellite stability.
| Author | : Ahmad Hamta |
| Publisher | : |
| Total Pages | : 45 |
| Release | : 2006 |
| Genre | : Endometrial neoplasms |
| ISBN | : 9789162868154 |
Download The BDII Rat Model of Endometrial Cancer Book in PDF, ePub and Kindle
| Author | : Ivana Marková |
| Publisher | : |
| Total Pages | : |
| Release | : 2012 |
| Genre | : Medicine |
| ISBN | : |
Download Molecular Biology of Endometrial Carcinoma Book in PDF, ePub and Kindle
Molecular Biology of Endometrial Carcinoma.
| Author | : Ulrich Pfeffer |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 591 |
| Release | : 2013-02-12 |
| Genre | : Medical |
| ISBN | : 9400758421 |
Download Cancer Genomics Book in PDF, ePub and Kindle
The combination of molecular biology, engineering and bioinformatics has revolutionized our understanding of cancer revealing a tight correlation of the molecular characteristics of the primary tumor in terms of gene expression, structural alterations of the genome, epigenetics and mutations with its propensity to metastasize and to respond to therapy. It is not just one or a few genes, it is the complex alteration of the genome that determines cancer development and progression. Future management of cancer patients will therefore rely on thorough molecular analyses of each single case. Through this book, students, researchers and oncologists will obtain a comprehensive picture of what the first ten years of cancer genomics have revealed. Experts in the field describe, cancer by cancer, the progress made and its implications for diagnosis, prognosis and treatment of cancer. The deep impact on the clinics and the challenge for future translational research become evident.
