Molecular Genetic And Statistical Techniques For Behavioral And Neural Research PDF Download
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Author | : Robert T. Gerlai |
Publisher | : Academic Press |
Total Pages | : 710 |
Release | : 2018-04-24 |
Genre | : Mathematics |
ISBN | : 0128041161 |
Download Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research Book in PDF, ePub and Kindle
Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior Written and edited by leading international experts
Author | : Wim E. Crusio |
Publisher | : Elsevier |
Total Pages | : 994 |
Release | : 1999-10-18 |
Genre | : Psychology |
ISBN | : 0080536867 |
Download Handbook of Molecular-Genetic Techniques for Brain and Behavior Research Book in PDF, ePub and Kindle
The book gives a broad overview of recombinant DNA techniques for the behavioral neuroscientist, with illustrative examples of applications. Species covered include rodents (mainly mice), Drosophila melanogaster, Caenorhabditis elegans and Danio rerio. Experimental techniques required to characterize the behavioral phenotypes of mutant animals is provided. Several aspects of novel molecular-genetic techniques are overviewed and possible research strategies are explained. The sections of the book start with general descriptions of techniques followed by illustrative examples. It is divided into six sections. Section 1, bioinformatics and genomics research. Section 2, top-down strategies, where the researcher starts with the phenotype and then analyzes the associated genes; bottom-up strategies, where the physiological chain leading to a phenotype is analyzed starting from the gene product. Section 3, transgenic approaches in rodents including overexpressing foreign genes and gene-targeting; systemic manipulation approaches directly targeting the central nervous system and methods used with invertebrates. Section 4, methods used to evaluate relevant behavioral phenotypes, including learning and aggression. Section 5, examples on molecular brain research in man. Section 6, ethical aspects of research in this field.
Author | : Robert T. Gerlai |
Publisher | : Academic Press |
Total Pages | : 616 |
Release | : 2020-04-03 |
Genre | : Medical |
ISBN | : 012817529X |
Download Behavioral and Neural Genetics of Zebrafish Book in PDF, ePub and Kindle
Behavioral and Neural Genetics of Zebrafish assembles the state-of-the-art methodologies and current concepts pertinent to their neurobehavioral genetics. Discussing their natural behavior, motor function, learning and memory, this book focuses on the fry and adult zebrafish, featuring a comprehensive account of modern genetic and neural methods adapted to, or specifically developed for, Danio rerio. Numerous examples of how these behavioral methods may be utilized for disease models using the zebrafish are presented, as is a section on bioinformatics and "big-data" related questions. Provides the most comprehensive snapshot of the fast-evolving zebrafish neurobehavior genetics field Describes behavioral, genetic and neural methods and concepts for use in adult and larval zebrafish Features examples of zebrafish models of human central nervous system disorders Discusses bioinformatics questions pertinent to zebrafish neurobehavioral genetics
Author | : Deborah Finkel |
Publisher | : Springer Science & Business Media |
Total Pages | : 306 |
Release | : 2013-07-09 |
Genre | : Psychology |
ISBN | : 1461474477 |
Download Behavior Genetics of Cognition Across the Lifespan Book in PDF, ePub and Kindle
Along with psychopathology, cognition has been one of the primary phenotypic focal points of the field of behavior genetics since its inception. Francis Galton’s 1874 examination of eminent families in Britain was among the earliest attempts to investigate whether cognitive achievements run in families. This volume presents current methodologies for understanding cognitive abilities that move beyond the outdated nature vs. nurture paradigm. Recent advances in both collection and statistical modeling of twin data, particularly longitudinal twin data, make this an especially advantageous moment to produce a work that presents a collection of the groundbreaking research on cognitive abilities across the lifespan. This volume presents an overview of the current state of quantitative and molecular genetic investigations into the many facets of cognitive performance and functioning across the lifespan.
Author | : Byron C. Jones |
Publisher | : CRC Press |
Total Pages | : 416 |
Release | : 2002-01-01 |
Genre | : Science |
ISBN | : 9781420048384 |
Download Neurobehavioral Genetics Book in PDF, ePub and Kindle
Neurobehavioral Genetics: Methods and Applications covers classic and contemporary approaches to the study of the brain and behavior, including basic and clinical research. This book is designed as a reference for investigators wishing to incorporate genetic methods into neurobehavioral research. A broad spectrum of methods are integrated, unlike any other publication currently in print. Neurobehavioral Genetics: Methods and Applications presents different models, from invertebrates to genetically defined mammals. Introductory chapters demonstrate the scope and power of genetic methods that can be applied to neurobehavioral research from statistical methods and linkage analysis to contemporary molecular genetic approaches to search for candidate genes. The second half of the book covers the applications of quantitative and molecular genetics in basic and clinical research. Topics covered include animal behavior and neurobiology and human clinical problems including neurodegenerative diseases and psychiatric disorders.
Author | : Hemin R. Chin |
Publisher | : CRC Press |
Total Pages | : 344 |
Release | : 2001-09-26 |
Genre | : Science |
ISBN | : 1420038478 |
Download Methods in Genomic Neuroscience Book in PDF, ePub and Kindle
The past few years have witnessed extraordinary advances in molecular genetic techniques and the accumulation of structural genomics information and resources in both human and model organisms. With the development of new technologies and the availability of resources like the sequence of eukaryotic genomes, problems of a previously unthinkable sco
Author | : Klaus A. Miczek |
Publisher | : Springer Nature |
Total Pages | : 517 |
Release | : 2022-06-06 |
Genre | : Medical |
ISBN | : 3031042565 |
Download Neuroscience of Social Stress Book in PDF, ePub and Kindle
Social stress has emerged as a research front in the neurosciences, and this volume highlights recent insights in brain mechanisms and methodological advances. The topics range from the evolutionary origins of coping with social challenges to neural mechanism-driven focus on novel treatment targets. The parallel presentation of work with animal models and human subjects is bound to be useful to a broad research community.
Author | : Carlo Botrugno |
Publisher | : Walter de Gruyter GmbH & Co KG |
Total Pages | : 229 |
Release | : 2023-03-06 |
Genre | : Science |
ISBN | : 3110765160 |
Download Bioethics and Racism Book in PDF, ePub and Kindle
This volume aims to explore some of the practices, conflicts, negotiations and struggles at the interplay of bioethics and racism. This requires shedding light on the hegemonic power relationships that condemn some population groups to a condition of subjugation, suffering, and oppression. By unpacking notions that have been taken for granted and dismantling rhetorics that are veiled in discourses and rationales pertaining to race and racism, we highlight possible ways in which bioethics can operate across disciplinary boundaries and strengthen its connection with equity and social justice, which also entails striving for a "bioethics in action".
Author | : Mayuri Mehta |
Publisher | : CRC Press |
Total Pages | : 362 |
Release | : 2021-12-09 |
Genre | : Computers |
ISBN | : 1000477762 |
Download Knowledge Modelling and Big Data Analytics in Healthcare Book in PDF, ePub and Kindle
Knowledge Modelling and Big Data Analytics in Healthcare: Advances and Applications focuses on automated analytical techniques for healthcare applications used to extract knowledge from a vast amount of data. It brings together a variety of different aspects of the healthcare system and aids in the decision-making processes for healthcare professionals. The editors connect four contemporary areas of research rarely brought together in one book: artificial intelligence, big data analytics, knowledge modelling, and healthcare. They present state-of-the-art research from the healthcare sector, including research on medical imaging, healthcare analysis, and the applications of artificial intelligence in drug discovery. This book is intended for data scientists, academicians, and industry professionals in the healthcare sector.
Author | : Douglas Wahlsten |
Publisher | : Academic Press |
Total Pages | : 300 |
Release | : 2019-03-01 |
Genre | : Science |
ISBN | : 0128128321 |
Download Genes, Brain Function, and Behavior Book in PDF, ePub and Kindle
Genes, Brain Function, and Behavior offers a concise description of the nervous system that processes sensory input and initiates motor movements. It reviews how behaviors are defined and measured, and how experts decide when a behavior is perturbed and in need of treatment. Behavioral disorders that are clearly related to a defect in a specific gene are reviewed, and the challenges of understanding complex traits such as intelligence, autism and schizophrenia that involve numerous genes and environmental factors are explored. New methods of altering genes offer hope for treating or even preventing difficulties that arise in our genes. This book explains what genes are, what they do in the nervous system, and how this impacts both brain function and behavior. Presents essential background, facts, and terminology about genes, brain function, and behavior Builds clear explanations on this solid foundation while minimizing technical jargon Explores in depth several single-gene and chromosomal neurological disorders Derives lessons from these clear examples and highlights key lessons in boxes Examines the intricacies of complex traits that involve multiple genetic and environmental factors by applying lessons from simpler disorders Explains diagnosis and definition Includes a companion website with Powerpoint slides and images for each chapter for instructors and links to resources