Molecular Dissection Of Complex Traits PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Molecular Dissection Of Complex Traits PDF full book. Access full book title Molecular Dissection Of Complex Traits.
Author | : Andrew H. Paterson |
Publisher | : CRC Press |
Total Pages | : 320 |
Release | : 2019-09-17 |
Genre | : Science |
ISBN | : 1420049380 |
Download Molecular Dissection of Complex Traits Book in PDF, ePub and Kindle
In the past 10 years, contemporary geneticists using new molecular tools have been able to resolve complex traits into individual genetic components and describe each such component in detail. Molecular Dissection of Complex Traits summarizes the state of the art in molecular analysis of complex traits (QTL mapping), placing new developments in thi
Author | : D.C. Rao |
Publisher | : Academic Press |
Total Pages | : 300 |
Release | : 2008-04-23 |
Genre | : Science |
ISBN | : 9780080569116 |
Download Genetic Dissection of Complex Traits Book in PDF, ePub and Kindle
The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. * Five sections on the latest advances in complex traits * Methods for testing with ethical, legal, and social implications * Hot topics include discussions on systems biology approach to drug discovery; using comparative genomics for detecting human disease genes; computationally intensive challenges, and more
Author | : Andrew H. Paterson |
Publisher | : CRC Press |
Total Pages | : 328 |
Release | : 2019-09-17 |
Genre | : Science |
ISBN | : 9781420049381 |
Download Molecular Dissection of Complex Traits Book in PDF, ePub and Kindle
In the past 10 years, contemporary geneticists using new molecular tools have been able to resolve complex traits into individual genetic components and describe each such component in detail. Molecular Dissection of Complex Traits summarizes the state of the art in molecular analysis of complex traits (QTL mapping), placing new developments in thi
Author | : Yuan-Ming Zhang |
Publisher | : Frontiers Media SA |
Total Pages | : 278 |
Release | : 2024-01-26 |
Genre | : Science |
ISBN | : 2832543693 |
Download Advances in Statistical Methods for the Genetic Dissection of Complex Traits in Plants Book in PDF, ePub and Kindle
Genome-wide association studies (GWAS) have been widely used in the genetic dissection of complex traits. However, there are still limits in current GWAS statistics. For example, (1) almost all the existing methods do not estimate additive and dominance effects in quantitative trait nucleotide (QTN) detection; (2) the methods for detecting QTN-by-environment interaction (QEI) are not straightforward and do not estimate additive and dominance effects as well as additive-by-environment and dominance-by-environment interaction effects, leading to unreliable results; and (3) no or too simple polygenic background controls have been employed in QTN-by-QTN interaction (QQI) detection. As a result, few studies of QEI and QQI for complex traits have been reported based on multiple-environment experiments. Recently, new statistical tools, including 3VmrMLM, have been developed to address these needs in GWAS. In 3VmrMLM, all the trait-associated effects, including QTN, QEI and QQI related effects, are compressed into a single effect-related vector, while all the polygenic backgrounds are compressed into a single polygenic effect matrix. These compressed parameters can be accurately and efficiently estimated through a unified mixed model analysis. To further validate these new GWAS methods, particularly 3VmrMLM, they should be rigorously tested in real data of various plants and a wide range of other species.
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 429 |
Release | : 2008-01-06 |
Genre | : Social Science |
ISBN | : 0309108675 |
Download Biosocial Surveys Book in PDF, ePub and Kindle
Biosocial Surveys analyzes the latest research on the increasing number of multipurpose household surveys that collect biological data along with the more familiar interviewerâ€"respondent information. This book serves as a follow-up to the 2003 volume, Cells and Surveys: Should Biological Measures Be Included in Social Science Research? and asks these questions: What have the social sciences, especially demography, learned from those efforts and the greater interdisciplinary communication that has resulted from them? Which biological or genetic information has proven most useful to researchers? How can better models be developed to help integrate biological and social science information in ways that can broaden scientific understanding? This volume contains a collection of 17 papers by distinguished experts in demography, biology, economics, epidemiology, and survey methodology. It is an invaluable sourcebook for social and behavioral science researchers who are working with biosocial data.
Author | : Yunbi Xu |
Publisher | : CABI |
Total Pages | : 756 |
Release | : 2010 |
Genre | : Science |
ISBN | : 1845936248 |
Download Molecular Plant Breeding Book in PDF, ePub and Kindle
Recent advances in plant genomics and molecular biology have revolutionized our understanding of plant genetics, providing new opportunities for more efficient and controllable plant breeding. Successful techniques require a solid understanding of the underlying molecular biology as well as experience in applied plant breeding. Bridging the gap between developments in biotechnology and its applications in plant improvement, Molecular Plant Breeding provides an integrative overview of issues from basic theories to their applications to crop improvement including molecular marker technology, gene mapping, genetic transformation, quantitative genetics, and breeding methodology.
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 388 |
Release | : 2001-01-19 |
Genre | : Social Science |
ISBN | : 0309171431 |
Download Cells and Surveys Book in PDF, ePub and Kindle
What can social science, and demography in particular, reasonably expect to learn from biological information? There is increasing pressure for multipurpose household surveys to collect biological data along with the more familiar interviewer-respondent information. Given that recent technical developments have made it more feasible to collect biological information in non-clinical settings, those who fund, design, and analyze survey data need to think through the rationale and potential consequences. This is a concern that transcends national boundaries. Cells and Surveys addresses issues such as which biologic/genetic data should be collected in order to be most useful to a range of social scientists and whether amassing biological data has unintended side effects. The book also takes a look at the various ethical and legal concerns that such data collection entails.
Author | : Michael Lynch |
Publisher | : Sinauer Associates Incorporated |
Total Pages | : 980 |
Release | : 1998-01 |
Genre | : Science |
ISBN | : 9780878934812 |
Download Genetics and Analysis of Quantitative Traits Book in PDF, ePub and Kindle
Professors Lynch and Walsh bring together the diverse array of theoretical and empirical applications of quantitative genetics in a work that is comprehensive and accessible to anyone with a rudimentary understanding of statistics and genetics.
Author | : Karl W. Broman |
Publisher | : Springer |
Total Pages | : 400 |
Release | : 2011-12-02 |
Genre | : Science |
ISBN | : 9781461417088 |
Download A Guide to QTL Mapping with R/qtl Book in PDF, ePub and Kindle
Comprehensive discussion of QTL mapping concepts and theory Detailed instructions on the use of the R/qtl software, the most featured and flexible software for QTL mapping Two case studies illustrate QTL analysis in its entirety
Author | : Nnadozie C. Oraguzie |
Publisher | : Springer Science & Business Media |
Total Pages | : 290 |
Release | : 2007-01-06 |
Genre | : Science |
ISBN | : 0387360115 |
Download Association Mapping in Plants Book in PDF, ePub and Kindle
This book provides both basic and advanced understanding of association mapping and an awareness of population genomics tools to facilitate mapping and identification of the underlying causes of quantitative trait variation in plants. It acts as a useful review of the marker technology, the statistical methodology, and the progress to date. It also offers guides to the use of single nucleotide polymorphisms (SNPs) in association studies.