Molecular Basis Of Pulmonary Disease PDF Download
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| Author | : Francis X. McCormack |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 443 |
| Release | : 2010-03-10 |
| Genre | : Medical |
| ISBN | : 1597453846 |
Download Molecular Basis of Pulmonary Disease Book in PDF, ePub and Kindle
The study of rare lung disorders enhances our understanding of common pulmonary diseases such as fibrosis and emphysema. Molecular Basis of Lung Disease: Insights from Rare Disorders brings together a panel of distinguished clinicians and molecular scientists who are experts in a range of rare lung diseases and their underlying molecular defects. Each chapter focuses on the pathogenic mechanisms and therapeutic targets suggested by basic research and follows an easy to read format: brief introduction followed by discussion of epidemiology, genetic basis and molecular pathogenesis, animal models, clinical presentation, diagnostic approaches, conventional management and treatment strategies, as well as future therapeutic targets and directions. Disorders ranging from the Marfan and Goodpasture’s syndromes to Sarcoidosis and alpha one titrypsin deficiency are treated in detail. Written for pulmonary clinicians and scientists alike, Molecular Basis of Lung Disease: Insights from Rare Disorders is a comprehensive and invaluable nesource that sheds new light on the molecular mechanisms influencing the clinical presentation and treatment strategies for these debilitating disorders.
| Author | : Jerome S. Brody |
| Publisher | : Saunders |
| Total Pages | : 248 |
| Release | : 1998 |
| Genre | : Medical |
| ISBN | : |
Download The Lung Book in PDF, ePub and Kindle
This user-friendly reference provides a basic understanding of the molecular biology underlying pulmonary diseases. Presents the background information necessary to understand the impact that molecular biology has on pulmonary medicine. Chapters begin with a list of basic concepts and a summary of the state-of-the-art information for each disease, starting with a clinical-molecular point of view and concluding with an annotated bibliography. Features excellent color illustrations and a thorough appendix!
| Author | : William B. Coleman |
| Publisher | : Academic Press |
| Total Pages | : 634 |
| Release | : 2019-11-23 |
| Genre | : Medical |
| ISBN | : 0128132582 |
Download Essential Concepts in Molecular Pathology Book in PDF, ePub and Kindle
Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology
| Author | : Venkataramana K Sidhaye |
| Publisher | : Academic Press |
| Total Pages | : 277 |
| Release | : 2017-03-09 |
| Genre | : Medical |
| ISBN | : 0128038810 |
Download Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease Book in PDF, ePub and Kindle
Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters. Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition. Provides a single source of information on lung epithelial junctions and transporters Discusses of the role of the epithelium in lung homeostasis and disease Includes capsule summaries of main conclusions as well as highlights of future directions in the field Covers the mechanistic basis for lung disease for a range of audiences
| Author | : Kamal Dua |
| Publisher | : Springer Nature |
| Total Pages | : 926 |
| Release | : 2021-07-02 |
| Genre | : Medical |
| ISBN | : 9813368276 |
Download Targeting Cellular Signalling Pathways in Lung Diseases Book in PDF, ePub and Kindle
The book comprehensively reviews and provides detailed insight into the cellular and molecular signalling mechanisms involved in pathophysiology of various respiratory diseases, towards developing effective therapeutic strategies in the management and treatment of lung disease. It also covers promising advances in the field of therapeutics that could lead to novel clinical therapies capable of preventing or reversing the disease features including novel strategies for targeting chronic lung diseases using advanced drug delivery systems. Importantly, the book examines the significance and relevance of the plant extracts and their constituents with therapeutic efficiencies against lung diseases. As such, the book offers a blend of translational, biological, chemical, and drug delivery aspects relevant to respiratory diseases, thus, offering a valuable resource for pulmonologists and translational researchers working in the field of pulmonary biology and respiratory medicine.
| Author | : William B. Coleman |
| Publisher | : Academic Press |
| Total Pages | : 659 |
| Release | : 2009-03-10 |
| Genre | : Medical |
| ISBN | : 0123859123 |
Download Molecular Pathology Book in PDF, ePub and Kindle
Molecular Pathology: The Molecular Basis of Human Disease provides a current and comprehensive view of the molecular basis and mechanisms of human disease. Combining accepted principles with broader theoretical concepts and with contributions from a group of experts, the book looks into disease processes in the context of traditional pathology and their implications for translational molecular medicine. It also discusses concepts in molecular biology and genetics, recent scientific and technological advances in modern pathology, the concept of ""molecular pathogenesis"" of disease, and how disease evolves from normal cells and tissues due to perturbations in molecular pathways. The book describes the integration of molecular and cellular pathogenesis using a bioinformatics approach and a systems biology approach to disease pathogenesis. It also discusses current and future strategies in molecular diagnosis of human disease, and the impact of molecular diagnosis on treatment decisions and the practice of personalized medicine. This book is a valuable resource for students, biomedical researchers, practicing physician-scientists who undertake disease-related basic science and translational research, and pathology residents and other postdoctoral fellows. * Exam Master® web site will host "Self-assessment" questions that students can use to study for the molecular section of the board exam * Companion Web Site – will host a complete set of PowerPoint slides: to include images from the book and additional images for teaching; course materials; lecture materials * Teaches from the perspective of “integrative systems biology, which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease * Outlines the principles and practice of molecular pathology * Explains the practice of “molecular medicine and the translational aspects of molecular pathology
| Author | : United States. Public Health Service. Office of the Surgeon General |
| Publisher | : |
| Total Pages | : 728 |
| Release | : 2010 |
| Genre | : Government publications |
| ISBN | : |
Download How Tobacco Smoke Causes Disease Book in PDF, ePub and Kindle
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
| Author | : Robert A. Stockley |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 220 |
| Release | : 1998 |
| Genre | : Medical |
| ISBN | : 9783764359683 |
Download Molecular Biology of the Lung Book in PDF, ePub and Kindle
The purpose of this two-volume work is to provide an update on the use of this powerful technology. As such, the books provide an insight in to the techniques for the non-specialist. Scientists embarking upon st udies in chronic lung disease will find a review of the current status of research. At the same time, the books are useful to clinicians, bo th specialist and academic, and to scientists already involved in the basic aspects of the pathogenesis of lung disease. Both volumes deal w ith basic mechanisms of cell biology, receptors and cellactivation and provide an insight as to how the technology influences our concepts o f pathogenesis and viceversa.
| Author | : Robert Stockley |
| Publisher | : Birkhäuser |
| Total Pages | : 216 |
| Release | : 1998-12-01 |
| Genre | : Medical |
| ISBN | : 9783764359690 |
Download Molecular Biology of the Lung Book in PDF, ePub and Kindle
The techniques and knowledge in molecular biology are advancing rapidly. The basic mechanisms involved in the pathogenesis of various lung conditions including asthma, COPD and lung cancer are being clarified by the application of this powerful technology. Genetic causes of single gene disorders such as cystic fibrosis and alpha-1 antitrypsin deficiency have now been well delineated. This progress leads to an understanding of the pathogenic process that result in disease. The purpose of Volumes I and II of "Molecular Biology of the Lung" is to provide an update on the use of this powerful technology. As such, the books provide an insight into the techniques for the non-specialist. Scientists embarking upon studies in chronic lung disease will find a review of the current status of research. At the same time, the books are useful to clinicians, both specialist and academic, and to scientists already involved in the basic aspects of the pathogenesis of lung disease. Both volumes deal with basic mechanisms of cell biology, receptors and cell activation and provides an insight as to how the technology influences our concepts of pathogenesis and vice versa.
| Author | : Jordan Prutkin |
| Publisher | : Remedica |
| Total Pages | : 207 |
| Release | : 2002 |
| Genre | : Lung Diseases |
| ISBN | : 1901346455 |
Download Genetics for Pulmonologists Book in PDF, ePub and Kindle
Our understanding of the relationship between genetics and pulmonary disorders is still evolving. In 1989 cloning of the gene that, when mutated, causes cystic fibrosis marked a great advance in the study of genetic diseases. Yet, over a decade later, understanding of how this genetic defect leads to colonization by bacteria and inflammation in the lung remains elusive.
