Molecular Basis For Mitochondrial Signaling PDF Download
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Author | : Tatiana K. Rostovtseva |
Publisher | : Springer |
Total Pages | : 388 |
Release | : 2017-05-12 |
Genre | : Science |
ISBN | : 3319555391 |
Download Molecular Basis for Mitochondrial Signaling Book in PDF, ePub and Kindle
This book covers recent advances in the study of structure, function, and regulation of metabolite, protein and ion translocating channels, and transporters in mitochondria. A wide array of cutting-edge methods are covered, ranging from electrophysiology and cell biology to bioinformatics, as well as structural, systems, and computational biology. At last, the molecular identity of two important channels in the mitochondrial inner membrane, the mitochondrial calcium uniporter and the mitochondrial permeability transition pore have been established. After years of work on the physiology and structure of VDAC channels in the mitochondrial outer membrane, there have been multiple discoveries on VDAC permeation and regulation by cytosolic proteins. Recent breakthroughs in structural studies of the mitochondrial cholesterol translocator reveal a set of novel unexpected features and provide essential clues for defining therapeutic strategies. Molecular Basis for Mitochondrial Signaling covers these and many more recent studies of mitochondria function, their communication with other organelles, and their critical roles in development, aging, and in a plethora of stressful or degenerative events. Authored by leading researchers in the field, this volume will be an indispensable reference resource for graduate students and academics working in related areas of biophysics and cell biology as well as for professionals within industry.
Author | : Peter Sutovsky |
Publisher | : Springer |
Total Pages | : 126 |
Release | : 2019-05-09 |
Genre | : Science |
ISBN | : 3030045706 |
Download Cellular and Molecular Basis of Mitochondrial Inheritance Book in PDF, ePub and Kindle
This new volume of our successful book series Advances in Anatomy, Embryology and Cell Biology is focused on mitochondrial inheritance in humans and both vertebrate and invertrebate animals including Drosophila, C. elegans, bivalve molusc Mytilus and livestock mammals. Special consideration is given to cellular mechanisms promoting uniparental inheritance of mitochondria and mitochondrial genes, evolutionary perspectives, and biomedical and epidemiological considerations. Contributed by five distinguished mitochondrial research teams from around the world, this volume will target a wide audience of physiologists, anatomists, cell, and developmental and evolutionary biologists, as well as physicians, veterinarians, livestock specialists and biomedical researchers.
Author | : Grant M. Hatch |
Publisher | : Frontiers Media SA |
Total Pages | : 105 |
Release | : 2022-01-11 |
Genre | : Science |
ISBN | : 2889740218 |
Download Mitochondrial Disorders: Biochemical and Molecular Basis of Disease Book in PDF, ePub and Kindle
Author | : C. P. Lee |
Publisher | : Academic Press |
Total Pages | : 267 |
Release | : 2014-11-27 |
Genre | : Science |
ISBN | : 1483297837 |
Download Molecular Basis of Mitochondrial Pathology Book in PDF, ePub and Kindle
The field of mitochondrial diseases is currently one of the rapidly growing fields of research in cell and molecular biology. This volume encompasses the latest development in this field of research. The chapters cover topics in a wide range of disciplines including biophysics, biochemistry, cell and molecular biology, molecular genetics, and clinical medicine. Summarizes growing evidence of the role of mitochondria in a large number of pathological conditions Brings together different approaches toward understanding mitochondria diseases Molecular and cellular biology Clinical physiology and medicine Details the crucial role this organelle plays in genetic regulation of various biological functions
Author | : Bruce Alberts |
Publisher | : |
Total Pages | : 0 |
Release | : 2002 |
Genre | : Cytology |
ISBN | : 9780815332183 |
Download Molecular Biology of The Cell Book in PDF, ePub and Kindle
Author | : Sten Orrenius |
Publisher | : CRC Press |
Total Pages | : 522 |
Release | : 2012-06-20 |
Genre | : Medical |
ISBN | : 1439880034 |
Download Mitochondrial Signaling in Health and Disease Book in PDF, ePub and Kindle
Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic
Author | : William S. Allison |
Publisher | : |
Total Pages | : |
Release | : 2009 |
Genre | : Active oxygen |
ISBN | : |
Download Mitochondrial Function Book in PDF, ePub and Kindle
Author | : Lawrence H. Lash |
Publisher | : Elsevier |
Total Pages | : 527 |
Release | : 2013-10-22 |
Genre | : Science |
ISBN | : 1483218619 |
Download Mitochondrial Dysfunction Book in PDF, ePub and Kindle
Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.
Author | : David M. Hockenbery |
Publisher | : Humana Press |
Total Pages | : 242 |
Release | : 2016-04-29 |
Genre | : Science |
ISBN | : 1493936123 |
Download Mitochondria and Cell Death Book in PDF, ePub and Kindle
This volume examines the role of mitochondria in different types of cell death, including apoptotic and necrotic cell deaths. Topics discussed include mitochondrial outer membrane permeabilization (MOMP) and the permeability transition pore; core processes such as calcium handling, fission and fusion, reactive oxygen species generation, and maintenance of mitochondrial DNA fidelity and protein folding homeostasis; and retrograde signaling between mitochondria and other cellular components, including the important role of mitochondria in antiviral immunity. The expertly authored chapters are drawn from multidisciplinary international perspectives, lending a nuanced and comprehensive approach to the material. Mitochondria and Cell Death, part of the Cell Death in Biology and Diseases series, is invaluable reading for graduate students, researchers, and clinicians in the fields of neuroscience, oncology, gastroenterology, and hepatology, as well as those interested in the study of mitochondria and cell biology.
Author | : Doris Abele |
Publisher | : John Wiley & Sons |
Total Pages | : 818 |
Release | : 2011-11-03 |
Genre | : Science |
ISBN | : 1444345966 |
Download Oxidative Stress in Aquatic Ecosystems Book in PDF, ePub and Kindle
Reactive oxygen species (ROS) are increasingly appreciated as down-stream effectors of cellular damage and dysfunction under natural and anthropogenic stress scenarios in aquatic systems. This comprehensive volume describes oxidative stress phenomena in different climatic zones and groups of organisms, taking into account specific habitat conditions and how they affect susceptibility to ROS damage. A comprehensive and detailed methods section is included which supplies complete protocols for analyzing ROS production, oxidative damage, and antioxidant systems. Methods are also evaluated with respect to applicability and constraints for different types of research. The authors are all internationally recognized experts in particular fields of oxidative stress research. This comprehensive reference volume is essential for students, researchers, and technicians in the field of ROS research, and also contains information useful for veterinarians, environmental health professionals, and decision makers.