Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Modulation Of T Cell Function And Survival By The Tumor Microenvironment PDF full book. Access full book title Modulation Of T Cell Function And Survival By The Tumor Microenvironment.
| Author | : Shahrzad Jalali |
| Publisher | : Frontiers Media SA |
| Total Pages | : 115 |
| Release | : 2023-09-26 |
| Genre | : Science |
| ISBN | : 283253435X |
| Author | : Qian Xiao |
| Publisher | : Frontiers Media SA |
| Total Pages | : 303 |
| Release | : 2023-02-01 |
| Genre | : Science |
| ISBN | : 2832513344 |
| Author | : Chi Hin Cho |
| Publisher | : Academic Press |
| Total Pages | : 242 |
| Release | : 2020-05-24 |
| Genre | : Science |
| ISBN | : 0128199385 |
Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies, Volume Eight, summarizes the molecular mechanisms of drug resistance in colorectal cancer, along with the most up-to-date therapeutic strategies available. The book discusses reasons why colorectal tumors become refractory during the progression of the disease, but also explains how drug resistance occurs during chemotherapy. In addition, users will find the current therapeutic strategies used by clinicians in their practice in treating colorectal cancer. The combination of conventional anticancer drugs with chemotherapy-sensitizing agents plays a pivotal role in improving the outcome of colorectal cancer patients, in particular those with drug-resistant cancer cells. From a clinical point-of-view, the content of this book provides clinicians with updated therapeutic strategies for a better choice of drugs for drug-resistant colorectal cancer patients. It will be a valuable source for cancer researchers, oncologists and several members of biomedical field who are dedicated to better treat patients with colorectal cancer. Presents a systemic summary of molecular mechanisms for a quick and in-depth understanding Updates current trends in the field with pioneering information on drug resistance Encompasses both basic and clinical approaches for a better understanding of unsolved problems from a holistic point-of-view
| Author | : Z. Kmiec |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 154 |
| Release | : 2013-06-29 |
| Genre | : Science |
| ISBN | : 3642565530 |
It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.
| Author | : Suzanne L. Walker |
| Publisher | : |
| Total Pages | : |
| Release | : 2018-10 |
| Genre | : |
| ISBN | : 9781635930184 |
| Author | : Sujit Kumar Bhutia |
| Publisher | : Springer Nature |
| Total Pages | : 284 |
| Release | : 2020-10-24 |
| Genre | : Medical |
| ISBN | : 9811569304 |
This book deals with the paradoxical role of autophagy in tumor suppression and tumor promotion in cancer cells. Autophagy plays opposing, context-dependent roles in tumors; accordingly, strategies based on inhibiting or stimulating autophagy could offer as potential cancer therapies. The book elucidates the physiological role of autophagy in modulating cancer metastasis, which is the primary cause of cancer-associated mortality. Further, it reviews its role in the differentiation, development, and activation of multiple immune cells, and its potential applications in tumor immunotherapy. In addition, it examines the effect of epigenetic modifications of autophagy-associated genes in regulating tumor growth and therapeutic response and summarizes autophagy’s role in the development of resistance to a variety of anti-cancer drugs in cancer cells. In closing, it assesses autophagy as a potential therapeutic target for cancer treatment. Given its scope, the book offers a valuable asset for all oncologists and researchers who wish to understand the potential role of autophagy in tumor biology.
| Author | : Jonathan Soboloff |
| Publisher | : CRC Press |
| Total Pages | : 258 |
| Release | : 2017-03-27 |
| Genre | : Medical |
| ISBN | : 149870509X |
T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.
| Author | : Fumito Ito |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 400 |
| Release | : 2018-09-03 |
| Genre | : Medical |
| ISBN | : 0323549500 |
Get a quick, expert overview of the latest clinical information and guidelines for cancer checkpoint inhibitors and their implications for specific types of cancers. This practical title by Drs. Fumito Ito and Marc Ernstoff synthesizes the most up-to-date research and clinical guidance available on immune checkpoint inhibitors and presents this information in a compact, easy-to-digest resource. It’s an ideal concise reference for trainee and practicing medical oncologists, as well as those in research. Discusses the current understanding of how to best harness the immune system against different types of cancer at various stages. Helps you translate current research and literature into practical information for daily practice. Presents information logically organized by disease site. Covers tumor immunology and biology; toxicities associated with immune checkpoint inhibitors; and future outlooks. Consolidates today’s available information on this timely topic into one convenient resource.
| Author | : M.E. Gershwin |
| Publisher | : Elsevier |
| Total Pages | : 468 |
| Release | : 2000-03-27 |
| Genre | : Medical |
| ISBN | : 9780080528458 |
Of the two disciplines in parallel development for two decades, tumor immunology and transplantation immunology, the latter has thrived and has led to some of the most critical discoveries in immunobiology. The former continues to thwart both scientists and clinicians alike. The goal of immunologists in modern day research is to develop a simple and effective means to manipulate cancer in vivo, possibly encompassing several venues: identifying a phenotypic marker and the use of either active or passive immunization; include the use of passive reagents carrying "warheads" to selectively destroy cancer cells; or altering the basic process of cell survival. This excellent multidiscipline-authored volume presents a theme which has not been well described before. The papers include both basic and clinical science and range from sophisticated molecular biology to little more than phenomenology (e.g. the increased association of cancer in some autoimmune diseases and increased presentation of autoimmune phenomena in malignant condition). This, however, is state-of-the-art. This collection of themes will be of use not only to bench scientists, but also to clinicians who treat patients. The book represents progress at the cutting edge of this discipline, and points the way to further developments in the "black box" of immunology.
| Author | : Jianmei Wu Leavenworth |
| Publisher | : Frontiers Media SA |
| Total Pages | : 244 |
| Release | : 2022-02-22 |
| Genre | : Medical |
| ISBN | : 2889744736 |
Topic Editor Dr. Lewis Shi received financial support from Varian Medical System, Inc. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
