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| Author | : Ester Orlandi |
| Publisher | : Frontiers Media SA |
| Total Pages | : 389 |
| Release | : 2021-07-27 |
| Genre | : Medical |
| ISBN | : 2889710882 |
| Author | : Tiziana Rancati |
| Publisher | : CRC Press |
| Total Pages | : 399 |
| Release | : 2019-06-11 |
| Genre | : Science |
| ISBN | : 1351983105 |
The treatment of a patient with radiation therapy is planned to find the optimal way to treat a tumour while minimizing the dose received by the surrounding normal tissues. In order to better exploit the possibilities of this process, the availability of accurate and quantitative knowledge of the peculiar responses of the different tissues is of paramount importance. This book provides an invaluable tutorial for radiation oncologists, medical physicists, and dosimetrists involved in the planning optimization phase of treatment. It presents a practical, accessible, and comprehensive summary of the field’s current research and knowledge regarding the response of normal tissues to radiation. This is the first comprehensive attempt to do so since the publication of the QUANTEC guidelines in 2010. Features: Addresses the lack of systemization in the field, providing educational materials on predictive models, including methods, tools, and the evaluation of uncertainties Collects the combined effects of features, other than dose, in predicting the risk of toxicity in radiation therapy Edited by two leading experts in the field
| Author | : Issam El Naqa |
| Publisher | : Springer |
| Total Pages | : 336 |
| Release | : 2015-06-19 |
| Genre | : Medical |
| ISBN | : 3319183052 |
This book provides a complete overview of the role of machine learning in radiation oncology and medical physics, covering basic theory, methods, and a variety of applications in medical physics and radiotherapy. An introductory section explains machine learning, reviews supervised and unsupervised learning methods, discusses performance evaluation, and summarizes potential applications in radiation oncology. Detailed individual sections are then devoted to the use of machine learning in quality assurance; computer-aided detection, including treatment planning and contouring; image-guided radiotherapy; respiratory motion management; and treatment response modeling and outcome prediction. The book will be invaluable for students and residents in medical physics and radiation oncology and will also appeal to more experienced practitioners and researchers and members of applied machine learning communities.
| Author | : Henning Willers |
| Publisher | : Springer Nature |
| Total Pages | : 370 |
| Release | : 2020-08-10 |
| Genre | : Medical |
| ISBN | : 3030497011 |
Molecular Targeted Radiosensitizers: Opportunities and Challenges provides the reader with a comprehensive review of key pre-clinical research components required to identify effective radiosensitizing drugs. The book features discussions on the mechanisms and markers of clinical radioresistance, pre-clinical screening of targeted radiosensitizers, 3D radiation biology for studying radiosensitizers, in vivo determinations of local tumor control, genetically engineered mouse models for studying radiosensitizers, targeting the DNA damage response for radiosensitization, targeting tumor metabolism to overcome radioresistance, radiosensitizers in the era of immuno-oncology, and more. Additionally, the book features discussions on high-throughput drug screening, predictive biomarkers, pre-clinical tumor models, and the influence of the tumor microenvironment and the immune system, with a specific focus on the challenges radiation oncologists and medical oncologists currently face in testing radiosensitizers in human cancers. Edited by two acclaimed experts in radiation biology and radiosensitizers, with thirteen chapters contributed by experts, this new volume presents an in-depth look at current developments within a rapidly moving field, with a look at where the field will be heading and providing comprehensive insight into the framework of targeted radiosensitzer development. Essential reading for investigators in cancer research and radiation biology.
| Author | : Simon S. Lo |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 433 |
| Release | : 2012-08-28 |
| Genre | : Medical |
| ISBN | : 364225604X |
Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.
| Author | : X. Allen Li |
| Publisher | : CRC Press |
| Total Pages | : 404 |
| Release | : 2011-01-27 |
| Genre | : Medical |
| ISBN | : 1439816352 |
Modern medical imaging and radiation therapy technologies are so complex and computer driven that it is difficult for physicians and technologists to know exactly what is happening at the point-of-care. Medical physicists responsible for filling this gap in knowledge must stay abreast of the latest advances at the intersection of medical imaging an
| Author | : Francesco Cellini |
| Publisher | : Frontiers Media SA |
| Total Pages | : 267 |
| Release | : 2022-12-01 |
| Genre | : Medical |
| ISBN | : 2832508235 |
| Author | : Jason Brownlee |
| Publisher | : Machine Learning Mastery |
| Total Pages | : 463 |
| Release | : 2020-01-14 |
| Genre | : Computers |
| ISBN | : |
Imbalanced classification are those classification tasks where the distribution of examples across the classes is not equal. Cut through the equations, Greek letters, and confusion, and discover the specialized techniques data preparation techniques, learning algorithms, and performance metrics that you need to know. Using clear explanations, standard Python libraries, and step-by-step tutorial lessons, you will discover how to confidently develop robust models for your own imbalanced classification projects.
| Author | : Michael C. Joiner |
| Publisher | : CRC Press |
| Total Pages | : 361 |
| Release | : 2018-08-28 |
| Genre | : Medical |
| ISBN | : 0429955405 |
Builds on success and reputation of previous editions Draws on the considerable teaching experience of an international author team, most notably the US and European Editors The gold-standard European text for training, adopted by ESTRO as a course book, as a text for the Royal College of Radiologists' radiobiology exam and by courses in the US Highly illustrated with new, 2 colour illustrations Clear and concise style, appropriate for trainees and also practising radiation oncologists requiring a ready reference to the subject Includes new chapters on stem cells, tissue response and the meeting point of meeting point of radiotherapy, radiobiology and physics
| Author | : International Atomic Energy Agency |
| Publisher | : |
| Total Pages | : 297 |
| Release | : 2017-04-12 |
| Genre | : Technology & Engineering |
| ISBN | : 9789201008152 |
Accuracy requirements in radiation oncology have been defined in multiple publications; however, these have been based on differing radiation technologies. In the meantime, the uncertainties in radiation dosimetry reference standards have been reduced and more detailed patient outcome data are available. No comprehensive literature on accuracy and uncertainties in radiotherapy has been published so far. The IAEA has therefore developed a new international consensus document on accuracy requirements and uncertainties in radiation therapy, to promote safer and more effective patient treatments. This publication addresses accuracy and uncertainty issues related to the vast majority of radiotherapy departments including both external beam radiotherapy and brachytherapy. It covers clinical, radiobiological, dosimetric, technical and physical aspects.
