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Miniaturized Analytical Devices

Miniaturized Analytical Devices
Author: Suresh Kumar Kailasa
Publisher: John Wiley & Sons
Total Pages: 324
Release: 2021-12-28
Genre: Science
ISBN: 3527347585
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Miniaturized Analytical Devices An in-depth overview of integrating functionalized nanomaterials with mass spectrometry, spectroscopy, electrophoresis, and other important analytical techniques Miniaturized Analytical Devices: Materials and Technology is an up-to-date resource exploring the analytical applications of miniaturized technology in areas such as clinical microbiology, pharmaceuticals, agriculture, and environmental analysis. The book covers the integration of functional nanomaterials in mass spectrometry, microscopy, electrophoresis, and more—providing the state-of-the-art information required for successfully implementing a range of chemical analysis techniques on microchips. Featuring contributions from a panel of international experts in the field, the book begins with an introduction to selected miniaturized devices, nanomaterials, and analytical methods. Subsequent sections describe functionalized nanomaterials (FNMs) for miniaturized devices and discuss techniques such as miniaturized mass spectrometry for bioassays and miniaturized microscopy for cell imaging. The book concludes by exploring a variety of applications of miniaturized devices in areas including metal analysis, bioimaging, DNA separation and analysis, molecular biology, and more. This timely volume: Surveys the current state of the field and provides a starting point for developing faster, more reliable, and more selective analytical devices Focuses on the practical applications of miniaturized analytical devices in materials science, clinical microbiology, the pharmaceutical industry, and environmental analysis Covers a wide range of materials and analytical techniques such as microvolume UV-VIS spectroscopy, microchip and capillary electrophoresis, and matrix assisted laser desorption ionization-mass spectrometry (MALDI-MS) analysis Discusses the role of miniaturized analytical devices in securing a green and sustainable future Miniaturized Analytical Devices: Materials and Technology is essential reading for analytical chemists, analytical laboratories, materials scientists, biologists, life scientists, and advanced students in related fields.

Micro- and Nanotechnology Enabled Applications for Portable Miniaturized Analytical Systems

Micro- and Nanotechnology Enabled Applications for Portable Miniaturized Analytical Systems
Author: Sabu Thomas
Publisher: Elsevier
Total Pages: 430
Release: 2021-10-10
Genre: Technology & Engineering
ISBN: 9780128237274
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Micro- and Nanotechnology Enabled Applications for Portable Miniaturized Analytical Systems outlines the basic principles of miniaturized analytical devices, such as spectrometric, separation, imaging and electrochemical miniaturized instruments. Concepts such as smartphone-enabled miniaturized detection systems and micro/nanomachines are also reviewed. Subsequent chapters explore the emerging application of these mobile devices for miniaturized analysis in various fields, including medicine and biomedicine, environmental chemistry, food chemistry, and forensic chemistry. This is an important reference source for materials scientists and engineers wanting to understand how miniaturization techniques are being used to create a range of efficient, sustainable electronic and optical devices. Miniaturization describes the concept of manufacturing increasingly smaller mechanical, optical, and electronic products and devices. These smaller instruments can be used to produce micro- and nanoscale components required for analytical procedures. A variety of micro/nanoscale materials have been synthesized and used in analytical procedures, such as sensing materials, sorbents, adsorbents, catalysts, and reactors. The miniaturization of analytical instruments can be applied to the different steps of analytical procedures, such as sample preparation, analytical separation, and detection, reducing the total cost of manufacturing the instruments and the needed reagents and organic solvents. Outlines how miniaturization techniques can be used to create new optical and electronic micro- and nanodevices Explores major application areas, including biomedicine, environmental science and security Assesses the major challenges of using miniaturization techniques

Micro- and Nanotechnology Enabled Applications for Portable Miniaturized Analytical Systems

Micro- and Nanotechnology Enabled Applications for Portable Miniaturized Analytical Systems
Author: Sabu Thomas
Publisher: Elsevier
Total Pages: 440
Release: 2021-10-12
Genre: Technology & Engineering
ISBN: 0128237287
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Micro- and Nanotechnology Enabled Applications for Portable Miniaturized Analytical Systems outlines the basic principles of miniaturized analytical devices, such as spectrometric, separation, imaging and electrochemical miniaturized instruments. Concepts such as smartphone-enabled miniaturized detection systems and micro/nanomachines are also reviewed. Subsequent chapters explore the emerging application of these mobile devices for miniaturized analysis in various fields, including medicine and biomedicine, environmental chemistry, food chemistry, and forensic chemistry. This is an important reference source for materials scientists and engineers wanting to understand how miniaturization techniques are being used to create a range of efficient, sustainable electronic and optical devices. Miniaturization describes the concept of manufacturing increasingly smaller mechanical, optical, and electronic products and devices. These smaller instruments can be used to produce micro- and nanoscale components required for analytical procedures. A variety of micro/nanoscale materials have been synthesized and used in analytical procedures, such as sensing materials, sorbents, adsorbents, catalysts, and reactors. The miniaturization of analytical instruments can be applied to the different steps of analytical procedures, such as sample preparation, analytical separation, and detection, reducing the total cost of manufacturing the instruments and the needed reagents and organic solvents. Outlines how miniaturization techniques can be used to create new optical and electronic micro- and nanodevices Explores major application areas, including biomedicine, environmental science and security Assesses the major challenges of using miniaturization techniques

Analytical Instrumentation

Analytical Instrumentation
Author: Gillian McMahon
Publisher: John Wiley & Sons
Total Pages: 318
Release: 2008-03-11
Genre: Science
ISBN: 9780470518557
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This valuable resource covers the principles of analytical instrumentation used by today's chemists and biologists and presents important advances in instrumentation, such as the drive to miniaturise and lab-on-a-chip devices. In terms of the lab-based analytical instrumentation, the five main categories of technique—spectroscopic, chromatographic, electrochemical, imaging and thermoanalytical, are included and presented in a practical, not theoretical way. Including relevant examples and applications in a number of fields such as healthcare, environment and pharmaceutical industry this book provides a complete overview of the instruments used within the chemistry industry, making this an important tool for professionals and students alike.

Miniaturization of Analytical Systems

Miniaturization of Analytical Systems
Author: Angel Rios
Publisher: Wiley
Total Pages: 384
Release: 2009-09-21
Genre: Science
ISBN: 9780470061107
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The book describes a general vision of the miniaturization of the analytical systems, including their principles, designs and applications. Through ten chapters the different aspects characterizing the miniaturized systems are developed. Thus, the two first chapters include the basic concepts behind miniaturization in analytical chemistry, as well as the mechanical and electronic tools needed for designing and fabricating miniaturized analytical systems. Chapters 3 to 6 represent the core of the book, as they take as the basis the analytical process and deal with the miniaturization of sample treatment (including the consequent automation), with sections devoted to the problems associated with sample introduction in micro(nano) systems; miniaturized systems for analyte separation, depending of the forces involved in moving the flow; and detection in micro-size environments. Following on, Chapters 7 and 8 will deal with the miniaturization of the entire process: from sample introduction to the generation of the corresponding analytical results. The last part of the book will deal with two aspects of miniaturized analytical systems directly connected to their usefulness: the design of portable miniaturized systems (interesting for performing field tests) and how to assure the practical reliability of the micro(nano) systems (quality control tests, performance and validation activities, as well as the robustness of the miniaturized depicted systems. The ruggedness of micro(nano) systems are briefly discussed and related to the tools for designing and fabricating described in the first chapters of the book.

Miniaturized Analytical Devices

Miniaturized Analytical Devices
Author: Suresh Kumar Kailasa
Publisher: John Wiley & Sons
Total Pages: 324
Release: 2021-12-17
Genre: Science
ISBN: 3527827226
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Miniaturized Analytical Devices An in-depth overview of integrating functionalized nanomaterials with mass spectrometry, spectroscopy, electrophoresis, and other important analytical techniques Miniaturized Analytical Devices: Materials and Technology is an up-to-date resource exploring the analytical applications of miniaturized technology in areas such as clinical microbiology, pharmaceuticals, agriculture, and environmental analysis. The book covers the integration of functional nanomaterials in mass spectrometry, microscopy, electrophoresis, and more—providing the state-of-the-art information required for successfully implementing a range of chemical analysis techniques on microchips. Featuring contributions from a panel of international experts in the field, the book begins with an introduction to selected miniaturized devices, nanomaterials, and analytical methods. Subsequent sections describe functionalized nanomaterials (FNMs) for miniaturized devices and discuss techniques such as miniaturized mass spectrometry for bioassays and miniaturized microscopy for cell imaging. The book concludes by exploring a variety of applications of miniaturized devices in areas including metal analysis, bioimaging, DNA separation and analysis, molecular biology, and more. This timely volume: Surveys the current state of the field and provides a starting point for developing faster, more reliable, and more selective analytical devices Focuses on the practical applications of miniaturized analytical devices in materials science, clinical microbiology, the pharmaceutical industry, and environmental analysis Covers a wide range of materials and analytical techniques such as microvolume UV-VIS spectroscopy, microchip and capillary electrophoresis, and matrix assisted laser desorption ionization-mass spectrometry (MALDI-MS) analysis Discusses the role of miniaturized analytical devices in securing a green and sustainable future Miniaturized Analytical Devices: Materials and Technology is essential reading for analytical chemists, analytical laboratories, materials scientists, biologists, life scientists, and advanced students in related fields.

Miniature Fluidic Devices for Rapid Biological Detection

Miniature Fluidic Devices for Rapid Biological Detection
Author: Sang-Hyun Oh
Publisher: Springer
Total Pages: 232
Release: 2018-01-23
Genre: Science
ISBN: 3319647474
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This book presents an overview of fundamental aspects of surface-based biosensors and techniques for enhancing their detection sensitivity and speed. It focuses on rapid detection using miniaturized sensors and describes the physical principles of nanoscale transducers, surface modifications, microfluidics and reaction engineering, diffusion and kinetics. A key challenge in the field of bioanalytical sensors is the rapid delivery of target biomolecules to the sensing surface. While various nanostructures have shown great promise in sensitive detection, diffusion-limited binding of analyte molecules remains a fundamental problem. Recently, many researchers have put forward novel schemes to overcome this challenge, such as nanopore channels, electrokinetics, and dielectrophoresis, to name but a few. This book provides the readers an up-to-date account on these technological advances.

Miniaturization and Mass Spectrometry

Miniaturization and Mass Spectrometry
Author: Severine le Gac
Publisher: Royal Society of Chemistry
Total Pages: 332
Release: 2008-12-03
Genre: Science
ISBN: 1847558941
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The recent explosion in the use of analytical chemistry, particularly in the biological sciences, has led to a need for fast, reliable and highly sensitive tools able to handle small sample sizes. This book illustrates how microfluidics and lab-on-a-chip devices can satisfy the growing need for miniaturized and enhanced analysis. They lend themselves well to mass spectrometric detection as they use samples in the low microlitre range and are handled on a chip. Miniaturization and Mass Spectrometry focuses on one particular technique, mass spectrometry, whose popularity has increased dramatically in the last two decades with the increase in use of biological analysis and the development of two "soft" ionization techniques, ESI and MALDI. These enable the analysis of large but fragile biological molecules such as DNA, proteins and oligosaccharides. The book starts with an introduction to the coupling of microfluidics to mass spectrometry techniques. It then goes on demonstrate the advantages of such a coupling: the MS analysis benefits from improved sample preparation when performed on a chip while MS yields more information on the sample handled on the chip compared to conventional optical detection. A history on the developments in this field, starting from the off-chip coupling to the on-chip ionization, is also provided. Daniel Figeys, a pioneer in the development of microfluidic systems for MS analysis, describes the early beginnings of this hyphenated analysis technique. Solutions to couple microfluidic systems to the two most popular ionization methods, ESI and MALDI, are presented throughout the chapters. Various examples are given of the application of this microfluidics-MS hyphenated analysis technique to proteomics, metabolomics, organic chemistry and forensics. Coverage is not limited to academic research. The development of commercialized systems and their current use for routine biological analysis are also presented. Lastly, a future vision of the integration of the mass spectrometer on the chip is raised, as a last step to yield fully portable systems for on-site analysis.

Handbook on Miniaturization in Analytical Chemistry

Handbook on Miniaturization in Analytical Chemistry
Author: Chaudhery Mustansar Hussain
Publisher: Elsevier
Total Pages: 368
Release: 2020-07-25
Genre: Science
ISBN: 012822553X
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Handbook on Miniaturization in Analytical Chemistry: Application of Nanotechnology provides a source of authoritative fundamentals, interdisciplinary knowledge and primary literature for researchers who want to fully understand how nano-technologies work. Covering all stages of analysis, from sample preparation to separation and detection, the book discusses the design and manufacturing technology of miniaturization and includes an entire section on safety risks, ethical, legal and social issues (ELSI), the economics of nanotechnologies, and a discussion on sustainability with respect to nano- and lab-on-chip technologies. This guide for students and researchers working on applications of nanotechnology in modern systems for analysis gives readers everything they need to know to bring their current practices up-to-date. Details the impacts of miniaturization and nanotechnology Includes coverage of the current challenges for scaling up nano-miniaturization design and manufacturing technology for analysis Provides the latest reference materials, including websites of interest and details on the latest research in every chapter

Miniaturization and Mass Spectrometry

Miniaturization and Mass Spectrometry
Author: Séverine Le Gac
Publisher: Royal Society of Chemistry
Total Pages: 333
Release: 2009
Genre: Science
ISBN: 085404129X
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Focussing on mass spectrometry, this book illustrates how microfluidics and lab-on-a-chip devices satisfy the need for miniaturized, enhanced chemical analysis.