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Milk, Mucosal Immunity and the Microbiome: Impact on the Neonate

Milk, Mucosal Immunity and the Microbiome: Impact on the Neonate
Author: P.L. Ogra
Publisher: S. Karger
Total Pages: 194
Release: 2020-04-24
Genre: Medical
ISBN: 3318066850

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Considerable advances have been made in science in order to understand the varied mixture of bioactive components in human milk. The 94th Nestlé Nutrition Institute Workshop was designed to provide a comprehensive overview of the latest findings in human milk research and its potential to modulate mucosal immunity, the microbiome, and its impact on the neonate. The publication provides a balanced state-of-the-art update on the current knowledge about milk, mucosal immunity, and the microbiome as well as their impact on breastfeeding in mammalian neonates. The first part reviews data on the immunology of milk and lactation from a historical perspective to the latest scientific findings. The second part discusses the microbiology of human milk and lactation in detail, with a focus on premature infants and necrotizing enterocolitis. And finally, in the third part, light is shed on the protective factors in human milk and their role in influencing the neonate’s immune system. Important new insights will provide great scientific support for all people seeking a deeper understanding of human milk and its immunological properties and will enlarge the knowledge of those who have already specialized in human milk research.


Global Landscape of Nutrition Challenges in Infants and Children

Global Landscape of Nutrition Challenges in Infants and Children
Author: K.F. Michaelsen
Publisher: Karger Medical and Scientific Publishers
Total Pages: 192
Release: 2020-01-28
Genre: Medical
ISBN: 3318066494

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Malnutrition among children remains a persistent problem around the world. This publication aims to map the challenges within the global landscape of childhood nutrition and considers the importance of nutrition both prior to conception and in children beyond two years of age. Session I provides an updated picture of malnutrition around the world, the recent progress that has been made in eliminating malnutrition in all its forms and several data limitations to track such progress. The role of milk in early life is covered in session II. The chapters describe different aspects of cow’s milk and the possible role of optimized plant proteins as an alternative to dairy ingredients in treating children with severe acute malnutrition. Session III considers the ramifications of environmental constraints to healthy child growth. The chapters cover the issue of how persistent gut damage and systemic inflammation can precipitate malnutrition as well as the putative effects of alterations in the gut microbiota. This overview of diverse issues is relevant to the epidemiology, biology of nutrition in early life, programmatic implications, and future directions.


Nutritional Care of Preterm Infants

Nutritional Care of Preterm Infants
Author: B. Koletzko
Publisher: Karger Medical and Scientific Publishers
Total Pages: 328
Release: 2014-04-15
Genre: Medical
ISBN: 3318026417

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Improved conditions of care for premature infants have led to markedly increased survival rates over the last few decades, particularly in very low and extremely low birth weight infants. Nutritional measures play a central role in the long-term outcome, health and quality of life of these premature infants. In this publication, leading experts from all 5 continents present the most recent evidence and critical analyses of nutrient requirements and the practice of nutritional care (with the focus on very low birth weight infants) to provide guidance for clinical application. After the introductory chapters, covering nutritional needs and research evidence in a more general manner, topics such as amino acids and proteins, lipids, microminerals and vitamins, parenteral and enteral nutrition as well as approaches to various disease conditions are addressed. Due to its focus on critical appraisals and recommendations, this book is of interest not only for the researcher who wants to keep up to date, but also for the clinician faced with premature infants in his practice.


Infant Feeding

Infant Feeding
Author: Isam Jaber Al-Zwaini
Publisher: BoD – Books on Demand
Total Pages: 160
Release: 2020-10-28
Genre: Medical
ISBN: 1839627190

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Feeding during the first two years of life is very important for the nutrition and growth of an infant. It has a great effect on early morbidity and mortality and long-term effects on health. Breastfeeding has many benefits for both the infant and mother, whereas formula feeding, although associated with disadvantages and problems, can be life-saving for infants who need it. This book examines many aspects of infant feeding and nutrition with chapters covering such topics as the impact of the first 1000 days of nutrition on child health and development, breastfeeding, factors behind the decision to breastfeed or formula feed, and the relationship between breastfeeding and gut microbiota, among others.


Human Milk

Human Milk
Author: Sharon M. Donovan
Publisher: S. Karger AG (Switzerland)
Total Pages: 0
Release: 2019
Genre: Breast milk
ISBN: 9783318063400

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Human milk contains all of the essential nutrients and other functional components thought to have short- and long-term neonatal health benefits, such as positive biological effects on growth, metabolism, cognition, and immunity. This publication brings together the world's experts who touch on the spectrum of current knowledge, from the history and mechanics of breastfeeding, its physiological and clinical effects, to the new surprises revealed by metabolomics and comparative biology. One of the key points made is that human milk is not only a source of essential nutrients, but also contains a variety of bioactive substances. These include essential microbes, long-chain fatty acids, complex oligosaccharides, nucleotides, and bioactive signaling proteins and hormones. This book provides clinicians and researchers with useful insights from multiple perspectives on the various aspects of human milk and lactation.


The Human Microbiome, Diet, and Health

The Human Microbiome, Diet, and Health
Author: Food Forum
Publisher: National Academies Press
Total Pages: 197
Release: 2013-02-27
Genre: Medical
ISBN: 030926586X

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The Food Forum convened a public workshop on February 22-23, 2012, to explore current and emerging knowledge of the human microbiome, its role in human health, its interaction with the diet, and the translation of new research findings into tools and products that improve the nutritional quality of the food supply. The Human Microbiome, Diet, and Health: Workshop Summary summarizes the presentations and discussions that took place during the workshop. Over the two day workshop, several themes covered included: The microbiome is integral to human physiology, health, and disease. The microbiome is arguably the most intimate connection that humans have with their external environment, mostly through diet. Given the emerging nature of research on the microbiome, some important methodology issues might still have to be resolved with respect to undersampling and a lack of causal and mechanistic studies. Dietary interventions intended to have an impact on host biology via their impact on the microbiome are being developed, and the market for these products is seeing tremendous success. However, the current regulatory framework poses challenges to industry interest and investment.


Neonatal Hematology

Neonatal Hematology
Author: Pedro A. de Alarcón
Publisher: Cambridge University Press
Total Pages: 501
Release: 2021-02-18
Genre: Medical
ISBN: 1108488986

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An essential guide to the pathogenesis, diagnosis and management of hematologic problems in the neonate, covering erythrocyte disorders, leukocyte disorders, immunologic disorders and hemostatic disorders. Guidance is practical, including blood test interpretation, advice on transfusions and reference ranges for hematological values.


Prebiotics and Probiotics in Human Milk

Prebiotics and Probiotics in Human Milk
Author: Michelle McGuire
Publisher: Academic Press
Total Pages: 506
Release: 2016-10-06
Genre: Medical
ISBN: 0128027460

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Prebiotics and Probiotics in Human Milk: Origins and Functions of Milk-Borne Oligosaccharides and Bacteria provides a comprehensive, yet approachable, treatise on what is currently known about the origins and functions of human milk oligosaccharides (HMO), the complex sugars in milk that are not digested by the infant. The book examines how HMOs and bacteria in human milk may function independently and coordinately to influence both maternal and infant health. Human milk is the only food “designed specifically to nourish humans, indeed representing the essence of a perfect “functional food. And although researchers have been studying its composition for decades, surprisingly little is really understood about the origins and functions of its myriad components, an area that is especially true for HMOs and bacteria. This book provides a thorough review of the newest research on these inter-related milk constituents as written by a team of experts from both academia and industry who actively conduct HMO and human milk microbiome research as they endeavor to apply this new knowledge to infant nutrition. Each chapter provides objective rationale for what research is still needed in this rapidly evolving area, also discussing the challenges and opportunities faced by the industry in adding HMO and microbes to infant food products. This book is a valuable resource for nutrition researchers focused on infant nutrition, food scientists and product developers working on infant formula, and clinicians interested in broadening their understanding of the benefits of human milk for infants. Presents a reader-friendly, highly-curated text that includes a review of the literature related to origins, variability, metabolism, and functions of HMO and human milk bacteria Discusses the potential implications of HMO and milk microbiota to industry – for instance, utilization in the dairy industry and infant formula Consists of learning aids, such as pull quotes, critical summary statements, and an extensive list of published literature throughout


Protecting Infants through Human Milk

Protecting Infants through Human Milk
Author: Larry K. Pickering
Publisher: Springer Science & Business Media
Total Pages: 506
Release: 2013-06-29
Genre: Medical
ISBN: 1475742428

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Protecting Infants through Human Milk: Advancing the Scientific Evidence provides a forum in which basic scientists, clinicians, epidemiologists, and policy makers exchange the latest findings regarding the effects of human milk and breastfeeding on infant and maternal health, thereby fostering new and promising collaborations. This volume also integrates data from animal and in vitro laboratory studies with clinical and population studies to examine human milk production and composition, the mechanisms of infant protection and/or risk from human milk feeding, and proposed interventions related to infant feeding practices. Additionally, it stimulates critical evaluation of, and advances in, the scientific evidence base and research methods, and identifies the research priorities in various areas.


Feeding During Late Infancy and Early Childhood

Feeding During Late Infancy and Early Childhood
Author: Olle Hernell
Publisher: Karger Medical and Scientific Publishers
Total Pages: 253
Release: 2005-01-01
Genre: Health & Fitness
ISBN: 3805579063

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In its resolution WHA54.2 (2001) the WHO recommends the promotion and support of exclusive breastfeeding for 6 months, and then the provision of safe and appropriate complementary foods whilst continuing breastfeeding until 2 years of age or beyond. The 56 Nutrition Workshop has been specifically developed to review the medical and scientific aspects of these topics and to sustain the Nestle Development Nutrition Program (NDNP).