Microrna In Human Infectious Diseases PDF Download
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| Author | : Vijay Kumar Prajapati |
| Publisher | : Elsevier |
| Total Pages | : 346 |
| Release | : 2024-01-23 |
| Genre | : Science |
| ISBN | : 0323996620 |
Download MicroRNA in Human Infectious Diseases Book in PDF, ePub and Kindle
MicroRNA in Human Infectious Diseases offers a detailed overview of the therapeutic and diagnostic role microRNAs can play in the treatment of various infectious diseases. Beginning with an introduction on microRNAs and their mechanisms, the book then delves into the therapeutic role of microRNAs in various categories of diseases: bacterial, viral, and parasitic. A wide range of diseases are explored in these sections, including sexually transmitted diseases, typhoid, tuberculosis, Dengue fever, Ebola, Covid-19, Malaria, Leishmaniasis, and Lymphatic filariasis. The final section of the book covers microRNA-based system approaches, considering aspects such as web-based tools available for detecting and predicting microRNA targets, and the latest technologies for modifying and manipulating microRNAs. This volume explores microRNA across a multitude of conditions and is an ideal reference for those involved in the investigation and development of treatments in this area. Includes foundational knowledge on microRNAs and the fundamental aspects of its biogenesis Explores the potential role microRNAs can play in therapeutics and diagnostics to treat various infectious diseases, including sexually-transmitted diseases, bacterial diseases, viral infections, and parasitic diseases Features a chapter dedicated to the role of microRNA for therapeutics in respiratory viral infections, such as Covid-19 Considers technologies used for manipulating and modifying microRNAs in preparation for applications to treat infectious diseases
| Author | : Charles H. Lawrie |
| Publisher | : John Wiley & Sons |
| Total Pages | : 702 |
| Release | : 2013-10-30 |
| Genre | : Science |
| ISBN | : 1118300343 |
Download MicroRNAs in Medicine Book in PDF, ePub and Kindle
MicroRNAs in Medicine provides an access point into the current literature on microRNA for both scientists and clinicians, with an up-to-date look at what is happening in the emerging field of microRNAs and their relevance to medicine. Each chapter is a comprehensive review, with descriptions of the latest microRNA research written by international leaders in their field. Opening with an introduction to what microRNAs are and how they function, the book goes on to explore the role of microRNAs in normal physiological functions, infectious diseases, non-infectious diseases, cancer, circulating microRNAs as non-invasive biomarkers, and finally their potential as novel therapeutics. Including background information on the field as well as reviews of the latest research breakthroughs, MicroRNAs in Medicine is a one-stop source of information to satisfy the specialists and non-specialists alike, appealing to students, researchers, and clinicians interested in understanding the potential of microRNAs in medicine and research.
| Author | : Shashwat Sharad |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 126 |
| Release | : 2019-11-20 |
| Genre | : Medical |
| ISBN | : 1789845327 |
Download Antisense Therapy Book in PDF, ePub and Kindle
Antisense Therapy offers a comprehensive, state-of-the art perspective on the role of antisense therapy in the treatment of human disease, with a special focus on cancer. Use of antisense oligonucleotides is a growing field of pharmaceutical and biotech companies and research programs for treatment of several diseases. This book summarizes and presents the best updates, therapeutic principles, methods, and applications in the field and offers meaningful information to move treatment discovery forward.
| Author | : Sunit K. Singh |
| Publisher | : |
| Total Pages | : |
| Release | : |
| Genre | : Electronic books |
| ISBN | : 9781315118031 |
Download MicroRNAs Book in PDF, ePub and Kindle
"MicroRNAs (miRNAs) play a key role in diverse regulatory pathways ranging from developmental control, cell differentiation, neural and immune system development. Many miRNAs are located in the human genome and frequently amplified, deleted or rearranged in cancer. Many viruses encode their own miRNAs in order to thrive during the course of their infection cycle. This book discusses the mechanism of miRNA biogenesis, virus encoded miRNAs, and the involvement of miRNAs in specific infectious or non-infectious diseases. "--Provided by publisher.
| Author | : Cesar Lopez-Camarillo |
| Publisher | : CRC Press |
| Total Pages | : 426 |
| Release | : 2013-02-22 |
| Genre | : Medical |
| ISBN | : 1466576774 |
Download MicroRNAs in Cancer Book in PDF, ePub and Kindle
MicroRNA (miRNA) biology is a cutting-edge topic in basic as well as biomedical research. This is a specialized book focusing on the current understanding of the role of miRNAs in the development, progression, invasion, and metastasis of diverse types of cancer. It also reviews their potential for applications in cancer diagnosis, prognosis, and th
| Author | : Zhabiz Golkar |
| Publisher | : |
| Total Pages | : |
| Release | : 2016 |
| Genre | : Medicine |
| ISBN | : |
Download Utility of Potent Anti-viral MicroRNAs in Emerging Infectious Diseases Book in PDF, ePub and Kindle
MicroRNAs (miRNAs) are small, noncoding RNA molecules that have emerged as important posttranscriptional regulators of gene expression. miRNA provides intracellular immune defense when the body is faced with challenges from transgenes, viruses, transposons, and aberrant mRNAs. miRNA molecules trigger gene silencing in eukaryotic cells. To date, more than 3,000 different human miRNAs (hsa-miRs) have been identified, and it is generally agreed that cellular gene regulation is significantly impacted by the presence of miRNAs. A single miRNA has the complex capacity to target multiple genes simultaneously. In a viral infection context, miRNAs have been connected with the interplay between host and pathogen, and occupy a major role in the host-parasite interaction and pathogenesis. While numerous viral miRNAs from DNA viruses have been identified, characterization of functional RNA virus-encoded miRNAs and their potential targets is still ongoing. Here, we describe an in silico approach to analyze the most recent Ebola virus (EBOV) genome sequences causing West African epidemics. We identified numerous "candidate" miRNAs that can be utilized to quell the Ebola virus. Future approaches will focus on experimental validation of these miRNAs during quelling the Ebola target transcripts for further elucidating their biological functions in primates and other animal models.
| Author | : Neetu Dahiya |
| Publisher | : Nova Science Publishers |
| Total Pages | : 0 |
| Release | : 2012 |
| Genre | : MicroRNA. |
| ISBN | : 9781620811528 |
Download MicroRNA Let-7 Book in PDF, ePub and Kindle
MicroRNAs are small non-coding RNAs involved in post-transcriptional regulation of gene expression. Thousands of miRNAs have been identified in different organisms including viruses, insects, plants and animals. MiRNAs has emerged as key regulators of important biological processes. The differential expression of miRNAs in various human diseases has made them potential candidates for developing novel therapies and personalized medicines. This book is focused on microRNA let-7, the second miRNA discovered in the year 2000 and one of the most studied miRNA. This book discusses various aspects of miRNA let-7 starting from its discovery, biogenesis, transcriptional and posttranscriptional regulation to its crucial role in various fundamental cellular processes such as development, stem cell maintenance and differentiation, regulation of signalling pathways in cancer, drug resistance and therapeutic potential in different human diseases.
| Author | : Helena J. Maier |
| Publisher | : Humana |
| Total Pages | : 278 |
| Release | : 2021-09-08 |
| Genre | : Medical |
| ISBN | : 9781071609026 |
Download Coronaviruses Book in PDF, ePub and Kindle
This detailed new edition provides a comprehensive collection of protocols applicable to all members of the Coronavirinae sub-family currently and that are also transferrable to other fields of virology. Beginning with a section on detection, discovery, and evolution, the volume continues with coverage of propagation and titration of coronaviruses, genome manipulation, study of virus-host interactions, as well as imaging coronavirus infections. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Coronaviruses: Methods and Protocols, Second Edition serves as a valuable guide to researchers working to identify and control viruses with increased potential to cross the species barrier and to develop the diagnostics, vaccines, and antiviral therapeutics that are required to manage future outbreaks in both humans and animals.
| Author | : Ibrokhim Y. Abdurakhmonov |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 460 |
| Release | : 2016-04-06 |
| Genre | : Medical |
| ISBN | : 953512272X |
Download RNA Interference Book in PDF, ePub and Kindle
RNA interference (RNAi), a hallmark of all biological sciences of twenty-first century, is an evolutionarily conserved and double-stranded RNA-dependent eukaryotic cell defense process. Opportunity to utilize an organisms own gene and to systematically induce and trigger RNAi for any desired sequence made RNAi an efficient approach for functional genomics, providing a solution for conventional longstanding obstacles in life sciences. RNAi research and application have significantly advanced during past two decades. This book RNA interference provides an updated knowledge and progress on RNAi in various organisms, explaining basic principles, types, and property of inducers, structural modifications, delivery systems/methodologies, and various successful bench-to-field or clinic applications and disease therapies with some aspects of limitations, alternative tools, safety, and risk assessment.
| Author | : Ulf Schmitz |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 352 |
| Release | : 2013-02-03 |
| Genre | : Medical |
| ISBN | : 9400755902 |
Download MicroRNA Cancer Regulation Book in PDF, ePub and Kindle
This edited reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. The main focus lies on computational methods and applications, together with cutting edge experimental techniques that are used to approach all aspects of microRNA regulation in cancer. We are sure that the emergence of high-throughput quantitative techniques will make this integrative approach absolutely necessary in the near future. This book will be a resource for researchers starting out with cancer microRNA research, but is also intended for the experienced researcher who wants to incorporate concepts and tools from systems biology and bioinformatics into his work. Bioinformaticians and modellers are provided with a general perspective on microRNA biology in cancer, and the state-of-the-art in computational microRNA biology.
