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Microbiome and Microbial Informatics

Microbiome and Microbial Informatics
Author: Zheng Zhang
Publisher: Frontiers Media SA
Total Pages: 230
Release: 2022-11-24
Genre: Science
ISBN: 2832506828

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The Human Microbiome, Diet, and Health

The Human Microbiome, Diet, and Health
Author: Food Forum
Publisher: National Academies Press
Total Pages: 197
Release: 2013-02-27
Genre: Medical
ISBN: 030926586X

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The Food Forum convened a public workshop on February 22-23, 2012, to explore current and emerging knowledge of the human microbiome, its role in human health, its interaction with the diet, and the translation of new research findings into tools and products that improve the nutritional quality of the food supply. The Human Microbiome, Diet, and Health: Workshop Summary summarizes the presentations and discussions that took place during the workshop. Over the two day workshop, several themes covered included: The microbiome is integral to human physiology, health, and disease. The microbiome is arguably the most intimate connection that humans have with their external environment, mostly through diet. Given the emerging nature of research on the microbiome, some important methodology issues might still have to be resolved with respect to undersampling and a lack of causal and mechanistic studies. Dietary interventions intended to have an impact on host biology via their impact on the microbiome are being developed, and the market for these products is seeing tremendous success. However, the current regulatory framework poses challenges to industry interest and investment.


The Chemistry of Microbiomes

The Chemistry of Microbiomes
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 133
Release: 2017-07-19
Genre: Science
ISBN: 0309458390

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The 21st century has witnessed a complete revolution in the understanding and description of bacteria in eco- systems and microbial assemblages, and how they are regulated by complex interactions among microbes, hosts, and environments. The human organism is no longer considered a monolithic assembly of tissues, but is instead a true ecosystem composed of human cells, bacteria, fungi, algae, and viruses. As such, humans are not unlike other complex ecosystems containing microbial assemblages observed in the marine and earth environments. They all share a basic functional principle: Chemical communication is the universal language that allows such groups to properly function together. These chemical networks regulate interactions like metabolic exchange, antibiosis and symbiosis, and communication. The National Academies of Sciences, Engineering, and Medicine's Chemical Sciences Roundtable organized a series of four seminars in the autumn of 2016 to explore the current advances, opportunities, and challenges toward unveiling this "chemical dark matter" and its role in the regulation and function of different ecosystems. The first three focused on specific ecosystemsâ€"earth, marine, and humanâ€"and the last on all microbiome systems. This publication summarizes the presentations and discussions from the seminars.


Follow Your Gut

Follow Your Gut
Author: Rob Knight
Publisher: Simon and Schuster
Total Pages: 128
Release: 2015-04-07
Genre: Health & Fitness
ISBN: 1476784752

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Allergies, asthma, obesity, acne: these are just a few of the conditions that may be caused—and someday cured—by the microscopic life inside us. The key is to understand how this groundbreaking science influences your health, mood, and more. In just the last few years, scientists have shown how the microscopic life within our bodies— particularly within our intestines—has an astonishing impact on our lives. Your health, mood, sleep patterns, eating preferences—even your likelihood of getting bitten by mosquitoes—can be traced in part to the tiny creatures that live on and inside of us. In Follow Your Gut, pioneering scientist Rob Knight pairs with award-winning science journalist Brendan Buhler to explain—with good humor and easy-to-grasp examples—why these new findings matter to everyone. They lead a detailed tour of the previously unseen world inside our bodies, calling out the diseases and conditions believed to be most directly impacted by them. With a practical eye toward deeper knowledge and better decisions, they also explore the known effects of antibiotics, probiotics, diet choice and even birth method on our children’s lifelong health. Ultimately, this pioneering book explains how to learn about your own microbiome and take steps toward understanding and improving your health, using the latest research as a guide.


Statistical Analysis of Microbiome Data

Statistical Analysis of Microbiome Data
Author: Somnath Datta
Publisher: Springer Nature
Total Pages: 349
Release: 2021-10-27
Genre: Medical
ISBN: 3030733513

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Microbiome research has focused on microorganisms that live within the human body and their effects on health. During the last few years, the quantification of microbiome composition in different environments has been facilitated by the advent of high throughput sequencing technologies. The statistical challenges include computational difficulties due to the high volume of data; normalization and quantification of metabolic abundances, relative taxa and bacterial genes; high-dimensionality; multivariate analysis; the inherently compositional nature of the data; and the proper utilization of complementary phylogenetic information. This has resulted in an explosion of statistical approaches aimed at tackling the unique opportunities and challenges presented by microbiome data. This book provides a comprehensive overview of the state of the art in statistical and informatics technologies for microbiome research. In addition to reviewing demonstrably successful cutting-edge methods, particular emphasis is placed on examples in R that rely on available statistical packages for microbiome data. With its wide-ranging approach, the book benefits not only trained statisticians in academia and industry involved in microbiome research, but also other scientists working in microbiomics and in related fields.


The Human Microbiota and Microbiome

The Human Microbiota and Microbiome
Author: Julian R Marchesi
Publisher: CABI
Total Pages: 209
Release: 2014-05-14
Genre: Medical
ISBN: 1780640498

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Thousands of different microbial species colonize the human body, and are essential for our survival. This book presents a review of the current understanding of human microbiomes, the functions that they bring to the host, how we can model them, their role in health and disease and the methods used to explore them. Current research into areas such as the long-term effect of antibiotics makes this a subject of considerable interest. This title is essential reading for researchers and students of microbiology.


The Human Microbiota

The Human Microbiota
Author: David N. Fredricks
Publisher: John Wiley & Sons
Total Pages: 348
Release: 2013-02-22
Genre: Science
ISBN: 1118409809

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The Human Microbiota offers a comprehensive review of all human-associated microbial niches in a single volume, focusing on what modern tools in molecular microbiology are revealing about human microbiota, and how specific microbial communities can be associated with either beneficial effects or diseases. An excellent resource for microbiologists, physicians, infectious disease specialists, and others in the field, the book describes the latest research findings and evaluates the most innovative research approaches and technologies. Perspectives from pioneers in human microbial ecology are provided throughout.


Microbiome-Host Interactions

Microbiome-Host Interactions
Author: D. Dhanasekaran
Publisher: CRC Press
Total Pages: 863
Release: 2021-04-01
Genre: Medical
ISBN: 1000353141

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Microbiota are a promising and fascinating subject in biology because they integrate the microbial communities in humans, animals, plants, and the environment. In humans, microbiota are associated with the gut, skin, and genital, oral, and respiratory organs. The plant microbial community is referred to as "holobiont," and it is influential in the maintenance and health of plants, which themselves play a role in animal health and the environment. The contents of Microbiome-Host Interactions cover all areas as well as new research trends in the fields of plant, animal, human, and environmental microbiome interactions. The book covers microbiota in polar soil environments, in health and disease, in Caenorhabditis elegans, and in agroecosystems, as well as in rice root and actinorhizal root nodules, speleothems, and marine shallow-water hydrothermal vents. Moreover, this book provides comprehensive accounts of advanced next-generation DNA sequencing, metagenomic techniques, high-throughput 16S rRNA sequencing, and understanding nucleic acid sequence data from fungal, algal, viral, bacterial, cyanobacterial, actinobacterial, and archaeal communities using QIIME software (Quantitative Insights into Microbial Ecology). FEATURES Summarizes recent insight in microbiota and host interactions in distinct habitats, including Antarctic, hydrothermal vents, speleothems, oral, skin, gut, feces, reproductive tract, soil, root, root nodules, forests, and mangroves Illustrates the high-throughput amplicon sequencing, computational techniques involved in the microbiota analysis, downstream analysis and visualization, and multivariate analysis commonly used for microbiome analysis Describes probiotics and prebiotics in the composition of the gut microbiota, skin microbiome impact in dermatologic disease prevention, and microbial communities in the reproductive tract of humans and animals Presents information in a reachable way for students, teachers, researchers, microbiologists, computational biologists, and other professionals who are interested in strengthening or enlarging their knowledge about microbiome analysis with next-generation DNA sequencing in the different branches of the sciences


The Human Microbiome

The Human Microbiome
Author:
Publisher: Academic Press
Total Pages: 104
Release: 2017-11-17
Genre: Science
ISBN: 0128137150

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Methods in Microbiology, Volume 44 presents the latest volume in the most prestigious series devoted to techniques and methodology in the field, with updated chapters that cover Metabolomics and the vaginal microbial ecosystem and health, Esophageal microbiome, Bioinformatics methods, Evolution of biomolecules, genomes and communities, and Gut microbial metabolism or the acquisition of the gut microbiome. Established for over 30 years, this comprehensive series provides ready-to-use recipes, the latest emerging techniques, and novel approaches on tried, tested and established methods. Written by recognized leaders and experts in the field Provides a comprehensive and cutting-edge review of current and emerging technologies in the field of clinical microbiology Presents discussions on newly emerging technologies


Microbiome Interplay and Control

Microbiome Interplay and Control
Author: Christine Moissl-Eichinger
Publisher: Frontiers Media SA
Total Pages: 421
Release: 2018-07-05
Genre:
ISBN: 288945505X

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In complex systems, such as our body or a plant, the host is living together with thousands of microbes, which support the entire system in function and health. The stability of a microbiome is influenced by environmental changes, introduction of microbes and microbial communities, or other factors. As learned in the past, microbial diversity is the key and low-diverse microbiomes often mirror out-of-control situations or disease. It is now our task to understand the molecular principles behind the complex interaction of microbes in, on and around us in order to optimize and control the function of the microbial community – by changing the environment or the addition of the right microorganisms. This Research Topic focuses on studies (including e.g. original research, perspectives, mini reviews, and opinion papers) that investigate and discuss: 1) The role of the microbiome for the host/environmental system 2) The exchange and change of microbes and microbial communities (interplay) 3) The influence of external factors toward the stability of a microbiome 4) Methods, possibilities and approaches to change and control a system’s microbiome (e.g. in human or plant disease) 5) Experimental systems and approaches in microbiome research. The articles span the areas: human health and disease, animal and plant microbiomes, microbial interplay and control, methodology and the built environment microbiome.