Microbial Genomics And Drug Discovery PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Microbial Genomics And Drug Discovery PDF full book. Access full book title Microbial Genomics And Drug Discovery.
Author | : Thomas J. Dougherty |
Publisher | : CRC Press |
Total Pages | : 256 |
Release | : 2003-05-14 |
Genre | : Science |
ISBN | : 0824755138 |
Download Microbial Genomics and Drug Discovery Book in PDF, ePub and Kindle
Examines bioinformatic and genomic approaches for the identification, detection, selection, and validation of new antibacterial targets and vaccine candidates. Explores potential pathways for effective infection control, inhibition of antibacterial resistance, and acceleration of drug discovery processes. Illustrates the use of Pathway Tools in a genomics-based drug discovery project.
Author | : Thomas J. Dougherty |
Publisher | : CRC Press |
Total Pages | : 264 |
Release | : 2003-05-14 |
Genre | : Science |
ISBN | : 9780824740412 |
Download Microbial Genomics and Drug Discovery Book in PDF, ePub and Kindle
Exploring innovative routes of drug discovery in the postgenomic era, Microbial Genomics and Drug Discovery examines bioinformatic and genomic approaches for the identification, detection, selection, and validation of new antibacterial targets and vaccine candidates. The book discusses potential pathways for effective infection control, inhibition of antibacterial resistance, and acceleration of the drug discovery process. This comprehensive reference describes procedures to recognize common targets in various bacterial species for the design of broad-spectrum antibiotics and clearly illustrates the use of pathway tools in a genomics-based drug discovery project.
Author | : Claire M. Fraser |
Publisher | : Humana Press |
Total Pages | : 0 |
Release | : 2010-12-09 |
Genre | : Science |
ISBN | : 9781617374111 |
Download Microbial Genomes Book in PDF, ePub and Kindle
This collection of diverse articles by the pioneers of modern genomics takes stock of the current state of the field and elucidates the contribution that sequencing genomes has made to our understanding of microbial metabolism and evolution. Through twenty-eight thought-provoking chapters, the authors describe some of the most common computational methods and their applications to studying pathogenic microorganisms, show how genomics can be used to reconstruct the history and dynamism of the microbial world, and discuss issues as diverse as reconstruction of metabolic pathways, cell cycle processes, microbial evolution, metagenomics, and vaccine development. Additional chapters deal with microarrays and expression analysis and the role of genomic in drug discovery.
Author | : Ipek Kurtböke |
Publisher | : Academic Press |
Total Pages | : 354 |
Release | : 2017-03-31 |
Genre | : Medical |
ISBN | : 012805140X |
Download Microbial Resources Book in PDF, ePub and Kindle
Microbial Resources: From Functional Existence in Nature to Applications provides an exciting interdisciplinary journey through the rapidly developing field of microbial resources, including relationships to aspects of microbiology. Covers the functional existence of microorganisms in nature, as well as the transfer of this knowledge for industrial and other applications. Examines the economic perspective of revealing the potential value of microbial material and figuring it into socio-economic value; legal perspectives; and how to organize a fair allotment of socio-economic benefits to all stakeholders who have effectively contributed to the preservation, study, and exploitation of microbiological material. Covers aspects of foundational information related to microbiology, microbial ecology, and diversity, as well as new advances in microbial genomics Provides information on the utilization of microbial resources in biotechnology Covers legislative issues and related law in biodiscovery Fills a need for a very broad audience and is a good resource for microbiologists seeking to know the extent of microbiology approaches, the policies associated with microbiology, and potential career paths for researchers Has significant added value due to the inclusion of comprehensive coverage of the biology, ecology, biochemistry and international legislation surrounding these applications
Author | : Jizhong Zhou |
Publisher | : John Wiley & Sons |
Total Pages | : 624 |
Release | : 2004-03-19 |
Genre | : Science |
ISBN | : 9780471071907 |
Download Microbial Functional Genomics Book in PDF, ePub and Kindle
Microbial Functional Genomics offers a timely summary of the principles, approaches, and applications. It presents a comprehensive review of microbial functional genomics, covering microbial diversity, microbial genome sequencing, genomic technologies, genome-wide functional analysis, applied functional genomics, and future directions. An introduction will offer a definition of the field and an overview of the historical and comparative genomics aspects.
Author | : Huseyin Tombuloglu |
Publisher | : Academic Press |
Total Pages | : 0 |
Release | : 2024-05-01 |
Genre | : Science |
ISBN | : 9780443188664 |
Download Microbial Genomics: Clinical, Pharmaceutical, and Industrial Applications Book in PDF, ePub and Kindle
Microbial Genomics: Clinical, Pharmaceutical and Industrial Applications focuses on the various applications of microbial genomics in clinical, pharmaceutical, and industrial fields. The book consists of four parts devoted to bacterial, viral, and fungal genomics, as well as their applications in clinical, pharmaceutical, and industrial fields. Chapters are written by experts in their respective disciplines and are tightly organized with an introduction to detailed descriptions, available software implementation, applications, advanced topics, summaries, analytic questions, exercises, and suggested readings. Throughout this book, the latest genomics and biotechnological developments and discoveries as well as open problems and future challenges on microbial genomics are highlighted. Readers will be introduced to state-of-the-art developments and trends of microbial genomics, its clinical, pharmaceutical, and industrial applications.
Author | : Kishore R. Sakharkar |
Publisher | : CRC Press |
Total Pages | : 451 |
Release | : 2022-09-01 |
Genre | : Science |
ISBN | : 1000795713 |
Download Post-genomic Approaches in Drug and Vaccine Development Book in PDF, ePub and Kindle
Over the past decade, genome sequencing projects and the associated efforts have facilitated the discovery of several novel disease targets and the approval of several innovative drugs. To further exploit this data for human health and disease, there is a need to understand the genome data itself in detail, discover novel targets, understand their role in physiological pathways and associated diseases, with the aim to translate these discoveries to clinical and preventive medicine. It is equally important to understand the labors and limitations in integrating clinical phenotypes with genomic, transcriptomic, proteomic and metabolomic approaches. T
Author | : Prashant Kesharwani |
Publisher | : Academic Press |
Total Pages | : 434 |
Release | : 2020-05-15 |
Genre | : Medical |
ISBN | : 0128184817 |
Download Drug Discovery Targeting Drug-Resistant Bacteria Book in PDF, ePub and Kindle
Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included. Pharmaceutical scientists, microbiologists, medical professionals, pathologists, researchers in the field of drug discovery, infectious diseases and microbial drug discovery both in academia and in industrial settings will find this book helpful. Written by scientists with extensive industrial experience in drug discovery Provides a balanced view of the field, including its challenges and future directions Includes a special chapter on the identification and development of drugs against pathogens which exhibit the potential to be used as weapons of war
Author | : Institute of Medicine |
Publisher | : National Academies Press |
Total Pages | : 429 |
Release | : 2013-05-02 |
Genre | : Science |
ISBN | : 0309268192 |
Download The Science and Applications of Microbial Genomics Book in PDF, ePub and Kindle
Over the past several decades, new scientific tools and approaches for detecting microbial species have dramatically enhanced our appreciation of the diversity and abundance of the microbiota and its dynamic interactions with the environments within which these microorganisms reside. The first bacterial genome was sequenced in 1995 and took more than 13 months of work to complete. Today, a microorganism's entire genome can be sequenced in a few days. Much as our view of the cosmos was forever altered in the 17th century with the invention of the telescope, these genomic technologies, and the observations derived from them, have fundamentally transformed our appreciation of the microbial world around us. On June 12 and 13, 2012, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to discuss the scientific tools and approaches being used for detecting and characterizing microbial species, and the roles of microbial genomics and metagenomics to better understand the culturable and unculturable microbial world around us. Through invited presentations and discussions, participants examined the use of microbial genomics to explore the diversity, evolution, and adaptation of microorganisms in a wide variety of environments; the molecular mechanisms of disease emergence and epidemiology; and the ways that genomic technologies are being applied to disease outbreak trace back and microbial surveillance. Points that were emphasized by many participants included the need to develop robust standardized sampling protocols, the importance of having the appropriate metadata, data analysis and data management challenges, and information sharing in real time. The Science and Applications of Microbial Genomics summarizes this workshop.
Author | : Karen Joy Shaw |
Publisher | : Springer Science & Business Media |
Total Pages | : 513 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 1592591728 |
Download Pathogen Genomics Book in PDF, ePub and Kindle
Leading infectious disease researchers and pharmaceutical scientists comprehensively review the latest genomic technologies and their application to the prevention, diagnosis, and treatment. The authors' cross-disciplinary approach, with expertise acquired from studying disease-causing viruses, bacteria, fungi, and protozoa, reveals how sequence information from diverse pathogens has uncovered novel targets for drug discovery, antigenic determinants for vaccine development, as well as diagnostic tools. The authors also discuss the application of DNA micoarrays and the impact of genome sequencing comparisons on the discovery and choices of novel drug targets. The result is a better understanding how genomic information can reveal the fundamentals of microbial pathogenesis and how organisms interact with their host environment.