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Microarrays for an Integrative Genomics

Microarrays for an Integrative Genomics
Author: Isaac S. Kohane
Publisher: Bradford Books
Total Pages: 306
Release: 2003
Genre: Science
ISBN: 9780262112710

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An introduction to the use of DNA microarrays in functional genomics.


DNA Microarrays and Gene Expression

DNA Microarrays and Gene Expression
Author: Pierre Baldi
Publisher: Cambridge University Press
Total Pages: 238
Release: 2011-04-28
Genre: Science
ISBN: 9781139437608

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Massive data acquisition technologies, such as genome sequencing, high-throughput drug screening, and DNA arrays are in the process of revolutionizing biology and medicine. Using the mRNA of a given cell, at a given time, under a given set of conditions, DNA microarrays can provide a snapshot of the level of expression of all the genes in the cell. Such snapshots can be used to study fundamental biological phenomena such as development or evolution, to determine the function of new genes, to infer the role individual genes or groups of genes may play in diseases, and to monitor the effect of drugs and other compounds on gene expression. Originally published in 2002, this inter-disciplinary introduction to DNA arrays will be of value to anyone with an a interest in this powerful technology.


Functional Genomics

Functional Genomics
Author: Michael J. Brownstein
Publisher: Springer Science & Business Media
Total Pages: 264
Release: 2008-02-03
Genre: Science
ISBN: 159259364X

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This collection of robust, readily reproducible methods for microarray-based studies includes expert guidance in the optimal data analysis and informatics. On the methods side are proven techniques for monitoring subcellular RNA localization en masse, for mapping chromosomes at the resolution of a single gene, and for surveying the steady-state genome-wide distribution of DNA binding proteins in vivo. For those workers dealing with massive data sets, the book discusses the methodological aspects of data analysis and informatics in the design of microarray experiments, the choice of test statistic, and the assessment of observational significance, data reduction, and clustering.


DNA Microarrays

DNA Microarrays
Author: Mark Schena
Publisher: Scion Publishing Ltd
Total Pages: 289
Release: 2007-10-01
Genre: Science
ISBN: 1907904395

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DNA Microarrays: Methods Express covers the very latest in DNA microarray technology, with a clear focus on how these techniques can be used in the lab to gain the very best results. The authors are from some of the leading laboratories in the field and write with real authority on the latest methodology. Every chapter provides detailed step-by-step protocols with valuable hints and tips for success, as well as giving typical experimental results and selected literature citations. This book is a 'must have' manual for researchers in all fields of biology, medicine and agriculture.


Microarray Data Analysis

Microarray Data Analysis
Author: Michael J. Korenberg
Publisher: Springer Science & Business Media
Total Pages: 569
Release: 2008-02-03
Genre: Science
ISBN: 1597453900

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In this new volume, renowned authors contribute fascinating, cutting-edge insights into microarray data analysis. Information on an array of topics is included in this innovative book including in-depth insights into presentations of genomic signal processing. Also detailed is the use of tiling arrays for large genomes analysis. The protocols follow the successful Methods in Molecular BiologyTM series format, offering step-by-step instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding pitfalls.


Applying Genomic and Proteomic Microarray Technology in Drug Discovery

Applying Genomic and Proteomic Microarray Technology in Drug Discovery
Author: Robert S. Matson
Publisher: CRC Press
Total Pages: 313
Release: 2013-03-13
Genre: Medical
ISBN: 1439855641

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Microarrays play an increasingly significant role in drug discovery. The commercial landscape has changed dramatically over the past few years and researchers have made great advancements with regard to construction and use. Now in its second edition, Applying Genomic and Proteomic Microarray Technology in Drug Discovery highlights, describes, and