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Micro and Nanoengineering of the Cell Microenvironment

Micro and Nanoengineering of the Cell Microenvironment
Author: Ali Khademhosseini
Publisher: Artech House
Total Pages: 647
Release: 2008
Genre: Science
ISBN: 1596931493

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Supported with 140 illustrations, the volume exhaustively covers the micro- and nano-system technologies involved in developing cell-based bioengineering applications. You get full details on efforts to engineer the soluble and insoluble cell microenvironments, including the latest advances in microfluidic devices, surface patterning, 3D scaffolds, and techniques for engineering cellular mechanical properties and topography.


Micro- and Nanoengineering of the Cell Surface

Micro- and Nanoengineering of the Cell Surface
Author: Jeffrey M Karp
Publisher: William Andrew
Total Pages: 395
Release: 2014-05-30
Genre: Science
ISBN: 1455731552

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Micro- and Nanoengineering of the Cell Surface explores the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phenotypes. The book is accessible for readers across industry, academia, and in clinical settings in multiple disciplines, including materials science, engineering, chemistry, biology, and medicine. Written by leaders in the field, it covers numerous cell surface engineering methods along with their current and potential applications in cell therapy, tissue engineering, biosensing, and diagnosis. The interface of chemistry, materials science, and biology presents many opportunities for developing innovative tools to diagnose and treat various diseases. However, cell surface engineering using chemistry and materials science approaches is a new and diverse field. This book provides a full coverage of the subject, introducing the fundamentals of cell membrane biology before exploring the key application areas. Demystifies the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phenotypes Provides a toolkit of micro- and nanoengineering approaches to the manipulation of the cell surface Unlocks the potential of cell surface manipulation for a range of new applications in the fields of in vitro research, cell therapy, tissue engineering, biosensing, and diagnostics


Micro/nanoscale Engineering of the Cell Microenvironment

Micro/nanoscale Engineering of the Cell Microenvironment
Author: Daniel Gallego-Perez
Publisher:
Total Pages: 229
Release: 2011
Genre:
ISBN:

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Abstract: The cellular microenvironment/niche plays a significant role in the regulation of a host of physiological and pathophysiological processes. Autonomous signals derived from the intrinsic cell machinery can be inhibited or potentiated by soluble or insoluble factors present in such niche in the form of chemical, structural, and topographical cues. Similarly, specific cell behaviors can be evoked by the same factors even in the absence of intracellular inputs. A normal or aberrant interplay between the cells and their niche could determine for example either the continuation of a regular biological process, or the onset of a disease. Consequently, a better understanding of the mechanisms underlying these cell-microenvironment interactions could help to develop novel therapies for a number of conditions.


Micro and Nanotechnologies in Engineering Stem Cells and Tissues

Micro and Nanotechnologies in Engineering Stem Cells and Tissues
Author: Murugan Ramalingam
Publisher: John Wiley & Sons
Total Pages: 394
Release: 2013-05-10
Genre: Science
ISBN: 111857480X

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A cutting-edge look at the application of micro and nanotechnologies in regenerative medicine The area at the interface of micro/nanotechnology and stem cells/tissue engineering has seen an explosion of activity in recent years. This book provides a much-needed overview of these exciting developments, covering all aspects of micro and nanotechnologies, from the fundamental principles to the latest research to applications in regenerative medicine. Written and edited by the top researchers in the field, Micro and Nanotechnologies in Engineering Stem Cells and Tissues describes advances in material systems along with current techniques available for cell, tissue, and organ studies. Readers will gain tremendous insight into the state of the art of stem cells and tissue engineering, and learn how to use the technology in their own research or clinical trials. Coverage includes: Technologies for controlling or regulating stem cell and tissue growth Various engineering approaches for stem cell, vascular tissue, and bone regeneration The design and processing of biocompatible polymers and other biomaterials Characterization of the interactions between cells and biomaterials Unrivaled among books of this kind, Micro and Nanotechnologies in Engineering Stem Cells and Tissues is the ultimate forward-looking reference for researchers in numerous disciplines, from engineering and materials science to biomedicine, and for anyone wishing to understand the trends in this transformative field.


Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms

Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms
Author: Xinyu Liu
Publisher: Academic Press
Total Pages: 406
Release: 2021-08-14
Genre: Business & Economics
ISBN: 0128242434

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Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms provides a comprehensive introduction to the state-of-the-art micro and nano systems that have recently been developed and applied to biophysical studies of cells and small organisms. These micro and nano systems span from microelectromechanical systems (MEMS) and microfluidic devices to robotic micro-nanomanipulation systems. These biophysical studies range from cell mechanics to the neural science of worms and Drosophila. This book will help readers understand the fundamentals surrounding the development of these tools and teach them the most recent advances in cellular and organismal biophysics enabled by these technologies. Comprehensive coverage of micro and nano-system technology and application to biophysical studies of cells and small organisms. Highlights the most recent advances in cellular and organismal biophysics enabled by micro and nano systems. Insightful outlook on future directions and trends in each chapter covering a sub-area of the book topic.


Integrative Mechanobiology

Integrative Mechanobiology
Author: Yu Sun
Publisher: Cambridge University Press
Total Pages: 385
Release: 2015-11-12
Genre: Technology & Engineering
ISBN: 1316462544

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The first of its kind, this comprehensive resource integrates cellular mechanobiology with micro-nano techniques to provide unrivalled in-depth coverage of the field, including state-of-the-art methods, recent advances, and biological discoveries. Structured in two parts, the first part offers detailed analysis of innovative micro-nano techniques including FRET imaging, electron cryo-microscopy, micropost arrays, nanotopography devices, laser ablation, and computational image analysis. The second part of the book provides valuable insights into the most recent technological advances and discoveries in areas such as stem cell, heart, bone, brain, tumor, and fibroblast mechanobiology. Written by a team of leading experts and well-recognised researchers, this is an essential resource for students and researchers in biomedical engineering.


Cells, Forces, and the Microenvironment

Cells, Forces, and the Microenvironment
Author: Charles M. Cuerrier
Publisher: CRC Press
Total Pages: 399
Release: 2015-03-02
Genre: Medical
ISBN: 9814613371

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With the recent development of new experimental approaches and methodologies, it is becoming clear that cells and tissues are not regulated by biochemical signals alone. Indeed, physical cues arising in the biological microenvironment are directly coupled to the biochemical regulation of living systems. This book provides a broad overview of how me


Tissue Engineering

Tissue Engineering
Author: Clemens van Blitterswijk
Publisher: Academic Press
Total Pages: 891
Release: 2014-12-10
Genre: Science
ISBN: 0124202101

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Tissue Engineering is a comprehensive introduction to the engineering and biological aspects of this critical subject. With contributions from internationally renowned authors, it provides a broad perspective on tissue engineering for students coming to the subject for the first time. In addition to the key topics covered in the previous edition, this update also includes new material on the regulatory authorities, commercial considerations as well as new chapters on microfabrication, materiomics and cell/biomaterial interface. Effectively reviews major foundational topics in tissue engineering in a clear and accessible fashion Includes state of the art experiments presented in break-out boxes, chapter objectives, chapter summaries, and multiple choice questions to aid learning New edition contains material on regulatory authorities and commercial considerations in tissue engineering


Nanoscale and Microscale Approaches for Engineering the in Vitro Cellular Microenvironment

Nanoscale and Microscale Approaches for Engineering the in Vitro Cellular Microenvironment
Author: Ali Khademhosseini
Publisher:
Total Pages: 364
Release: 2005
Genre:
ISBN:

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(cont.) To easily immobilize cells within channels, poly(ethylene glycol) microstructures were used to capture cells within low shear stress regions. These techniques also allowed for the fabrication of multiphenotype cell arrays. In addition, techniques were developed to control the interaction of cells within hydrogels by controlling the spatial properties of hydrogels.


Biomedical Engineering

Biomedical Engineering
Author: Hossein Hosseinkhani
Publisher: John Wiley & Sons
Total Pages: 324
Release: 2023-04-17
Genre: Technology & Engineering
ISBN: 3527347461

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An exploration of materials processing and engineering technology across a wide range of medical applications The field of biomedical engineering has played a vital role in the progression of medical development technology. Biomedical Engineering: Materials, Technology, and Applications covers key aspects of the field—from basic concepts to advanced level research for medical applications. The book stands as a source of inspiration for research on materials as well as their development and practical application within specialized industries. It begins with a discussion of what biomedical engineering is and concludes with a final chapter on the advancements of biomaterials technology in medicine. Offers comprehensive coverage of topics, including biomaterials, tissue engineering, bioreceptor interactions, and various medical applications Discusses applications in critical industries such as biomedical diagnosis, pharmaceutics, drug delivery, cancer detection, and more Serves as a reference for those in scientific, medical, and academic fields Biomedical Engineering takes an interdisciplinary look at how biomedical science and engineering technology are integral to developing novel approaches to major problems, such as those associated with disease diagnosis and drug delivery. By covering a full range of materials processing and technology-related subjects, it shares timely information for biotechnologists, material scientists, biophysicists, chemists, bioengineers, nanotechnologists, and medical researchers.