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Statistical Methods for Quality of Life Studies

Statistical Methods for Quality of Life Studies
Author: Mounir Mesbah
Publisher: Springer Science & Business Media
Total Pages: 358
Release: 2013-06-29
Genre: Medical
ISBN: 1475736258

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On October 16 and 17, 2000, we hosted an international workshop entitled "Statistical Design, Measurement, and Analysis of Health Related Quality of Life." The workshop was held in the beautiful city of Arradon, South Brittany, France with the main goal of fostering an interdisciplinary forum for discussion of theoretical and applied statistical issues arising in studies of health-related quality of life (HRQoL). Included were biostatisticians, psychometricians and public health professionals (e.g., physicians, sociologists, psychologists) active in the study ofHRQoL. In assembling this volume, we invited each conference participant to contribute a paper based on his or her presentation and the ensuing and very interesting discussions that took place in Arradon. All papers were peer-reviewed, by anonymous reviewers, and revised before final editing and acceptance. Although this process was quite time consuming, we believe that it greatly improved the volume as a whole, making this book a valuable contribution to the field ofHRQoL research. The volume presents a broad spectrum of papers presented at the Workshop, and thus illustrates the range of current research related to the theory, methods and applications of HRQoL, as well as the interdisciplinary nature ofthis work. Following an introduction written by Sir David Cox, it includes 27 articles organized into the following chapters.


Quality of Life

Quality of Life
Author: Peter M. Fayers
Publisher: John Wiley & Sons
Total Pages: 648
Release: 2016-01-19
Genre: Medical
ISBN: 1444337955

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The assessment of patient reported outcomes and health-related quality of life continue to be rapidly evolving areas of research and this new edition reflects the development within the field from an emerging subject to one that is an essential part of the assessment of clinical trials and other clinical studies. The analysis and interpretation of quality-of-life assessments relies on a variety of psychometric and statistical methods which are explained in this book in a non-technical way. The result is a practical guide that covers a wide range of methods and emphasizes the use of simple techniques that are illustrated with numerous examples, with extensive chapters covering qualitative and quantitative methods and the impact of guidelines. The material in this new third edition reflects current teaching methods and content widened to address continuing developments in item response theory, computer adaptive testing, analyses with missing data, analysis of ordinal data, systematic reviews and meta-analysis. This book is aimed at everyone involved in quality-of-life research and is applicable to medical and non-medical, statistical and non-statistical readers. It is of particular relevance for clinical and biomedical researchers within both the pharmaceutical industry and clinical practice.


Individual Quality of Life

Individual Quality of Life
Author: Charles Richard Boddington Joyce
Publisher: Taylor & Francis
Total Pages: 258
Release: 1999
Genre: Education
ISBN: 9789057024252

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The rubric "Quality of Life" first came to the explicit attention of the medical profession a little over thirty years ago. Despite the undoubted fact that each one of us has his or her own Quality of Life, be it good or bad, there is still no general agreement about its definition, or the manner in which it should be evaluated. Although much has been written about quality of life, this work has been largely concerned with population-based studies, especially in health policy & health economics. The importance of individual quality of life has been neglected, in part because of a failure to define quality of life itself with sufficient care, in part perhaps because of a belief that it is impossible to develop a meaningful method of measuring individual variables. It is a fundamental belief of the editors of this book that the primary focus of quality of life is & must continue to be the individual, who alone can define it & assess its changing personal significances. The individual perspective is of vital importance not only to patients but to their doctors too, & is more & more frequently proposed as the most meaningful measure of outcome in clinical research, especially in non-remitting or chronic conditions. Workers who wish to consider wider aspects of influences on the illnesses suffered by individuals & the health care that they receive will find much to stimulate them in the methods of documentation proposed in this book. Those mainly concerned with population samples rather than individuals may also find the sensitive methods of investigation proposed here not only to be applicable to their own areas of interest, but also rewarding in perhaps unexpected ways.


Quality of Life

Quality of Life
Author: Peter M. Fayers
Publisher: John Wiley & Sons
Total Pages: 460
Release: 2013-05-23
Genre: Medical
ISBN: 1118699459

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Quality of life studies form an essential part of the evaluation of any treatment. Written by two authors who are well respected within this field, Quality of Life: The Assessment, Analysis and Interpretation of Patient-reported Outcomes, Second Edition lays down guidelines on assessing, analysing and interpreting quality of life data. The new edition of this standard book has been completely revised, updated and expanded to reflect many methodological developments emerged since the publication of the first edition. Covers the design of instruments, the practical aspects of implementing assessment, the analyses of the data, and the interpretation of the results Presents all essential information on Quality of Life Research in one comprehensive volume Explains the use of qualitative and quantitative methods, including the application of basic statistical methods Includes copious practical examples Fills a need in a rapidly growing area of interest New edition accommodates significant methodological developments, and includes chapters on computer adaptive testing and item banking, choosing an instrument, systematic reviews and meta analysis This book is of interest for everyone involved in quality of life research, and it is applicable to medical and non-medical, statistical and non-statistical readers. It is of particular relevance for clinical and biomedical researchers within both the pharmaceutical industry and practitioners in the fields of cancer and other chronic diseases. Reviews of the First Edition – Winner of the first prize in the Basis of Medicine Category of the BMA Medical Book Competition 2001: “This book is highly recommended to clinicians who are actively involved in the planning, analysis and publication of QoL research.” CLINICAL ONCOLOGY “This book is highly recommended reading.” QUALITY OF LIFE RESEARCH


Quality of Life Research

Quality of Life Research
Author: Mark Rapley
Publisher: SAGE
Total Pages: 305
Release: 2003-03-18
Genre: Social Science
ISBN: 1847876706

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`Many books have been published on quality of life research in recent years, but few are as thought provoking or original as this one. It is essential reading for anyone who a serious and critical interest in this topic′ - Nurse Researcher `This was a fun book to read and I would suggest it be used for a graduate level seminar - where, of course, it would lead to a lively discussion′ - Quality of Life Research `Quality of life′ is one of the fastest growing areas of research and policy. The concept has an intuitive appeal as a measure of the well-being of individuals, communities and nations. It is increasingly promoted as an aid for political decisions and public funding. But what does the concept really mean? And how can it be operationalized in teaching and research? This is the first introductory text to offer a critical overview of the concept of quality of life and the ways in which it is researched. Using an inter-disciplinary approach, the book covers every aspect of the concept and its application - from the calculation of Quality-Adjusted Life Years to conversation analysis, and from the estimation of the quality of life of nation states to ethnographic studies of the life quality of individual disadvantaged people. The book fills a huge gap in teaching and research. Written with authority, and the need to produce an accessible critical introduction to the field, it will be of interest to students of sociology, psychology, public health and nursing, health economics, politics and medicine.


Design and Analysis of Quality of Life Studies in Clinical Trials

Design and Analysis of Quality of Life Studies in Clinical Trials
Author: Diane L. Fairclough
Publisher: CRC Press
Total Pages: 419
Release: 2010-01-07
Genre: Mathematics
ISBN: 1420061186

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Design Principles and Analysis Techniques for HRQoL Clinical TrialsSAS, R, and SPSS examples realistically show how to implement methods Focusing on longitudinal studies, Design and Analysis of Quality of Life Studies in Clinical Trials, Second Edition addresses design and analysis aspects in enough detail so that readers can apply statistical meth


Quality of Life and Pharmacoeconomics in Clinical Trials

Quality of Life and Pharmacoeconomics in Clinical Trials
Author: Bert Spilker
Publisher: Lippincott Williams & Wilkins
Total Pages: 1259
Release: 1996
Genre: Medical
ISBN: 9780781703321

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The Second Edition of this groundbreaking work refines the art and science of quality of life assessment and pharmacoeconomics and redefines the role of these evaluation parameters in clinical trials and health care decision-making. Dr. Spilker has assembled more than 200 experts from diverse clinical, research, and social science disciplines to provide a comprehensive reference on the methodology, interpretation, and use of quality of life and pharmacoeconomic studies. Expanded to four times its predecessor's size and scope, the Second Edition features: all-new sections on pharmacoeconomics and crucial health policy issues such as outcomes research a new, extensive section on cross-cultural and cross-national issues in quality of life assessment detailed information on specific tests and measures of quality of life comprehensive guidelines on choosing and administering tests and analyzing, interpreting, and presenting data many chapters on new topics such as phenomenology, assessment of spiritual status, and alternative/complementary medical treatments.