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Methods of Assessing the Reinforcing Properties of Abused Drugs

Methods of Assessing the Reinforcing Properties of Abused Drugs
Author: Michael A. Bozarth
Publisher: Springer Science & Business Media
Total Pages: 658
Release: 2012-12-06
Genre: Medical
ISBN: 1461248124

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Methods of Assessing the Reinforcing Properties of Abused Drugs presents a synopsis of the preclinical procedures used to assess drug reinforcement. Researchers using one technique are provided with an overview of the other available methods, and clinicians who wish to evaluate drug abuse research reports can gain the necessary background from this volume. Although emphasis is placed on the methodological aspects of assessing drug reinforcement, some of the scientific conclusions derived from using these techniques are also presented. This edited collection offers a lasting framework for interpreting the results of current experimental findings.


Methods of Behavior Analysis in Neuroscience

Methods of Behavior Analysis in Neuroscience
Author: Jerry J. Buccafusco
Publisher: CRC Press
Total Pages: 341
Release: 2000-08-29
Genre: Medical
ISBN: 1420041819

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Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic


Nonclinical Assessment of Abuse Potential for New Pharmaceuticals

Nonclinical Assessment of Abuse Potential for New Pharmaceuticals
Author: Carrie Markgraf
Publisher: Academic Press
Total Pages: 321
Release: 2015-07-14
Genre: Medical
ISBN: 0124202160

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Nonclinical Assessment of Abuse Potential for New Pharmaceuticals offers a complete reference on the current international regulatory guidelines and details best practice methodology for the three standard animal models used to evaluate abuse potential: physical dependence, self-administration and drug discrimination. This book also includes chapters on alternative models and examples of when you should use these alternatives. Case histories are provided at the end of the book to show how the data generated from the animal models play a pivitol role in the submission package for a new drug. By incorporating all of this information into one book, Nonclinical Assessment of Abuse Potential for New Pharmaceuticals is your single resource for everything you need to know to understand and implement the assessment of abuse liability. Provides a consolidated overview of the complex regulatory landscape Offers best practice methodology for conducting animal studies, including selection of doses and positive control agents that will help you improve your own abuse potential studies Includes real-life examples to illustrate how nonclinical data fit into the submission strategy


Testing for Abuse Liability of Drugs in Humans

Testing for Abuse Liability of Drugs in Humans
Author: Marian W. Fischman
Publisher:
Total Pages: 420
Release: 1989
Genre: Drug abuse
ISBN:

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Representatives from industry, academia and government discuss issues related to testing for drug abuse liability and dependence potential. Contributors critically assess current methods for evaluating drugs in human subjects and describe both the advantages and limitations of each approach. This information permits identification of areas in which further research and development are needed.


Testing and Evaluation of Drugs of Abuse

Testing and Evaluation of Drugs of Abuse
Author: Martin W. Adler
Publisher: Wiley
Total Pages: 320
Release: 1990
Genre: Medical
ISBN: 9780471567431

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This work describes how critical biological information on today's abused drugs is obtained in both laboratory and clinical settings. Recent methodological advances, both great and small, are presented in a concise manner by experienced researchers and scholars. The text covers wholesale innovations in methodology, in addition to simple modifications of existing methods that often yield great advances, and the strengths and weaknesses of all methods are assessed. The survey is comprehensive and uncovers key characteristics of abused drugs at the receptor level, on animal behavior, and in humans.


Pathways of Addiction

Pathways of Addiction
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 330
Release: 1996-11-01
Genre: Medical
ISBN: 0309055334

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Drug abuse persists as one of the most costly and contentious problems on the nation's agenda. Pathways of Addiction meets the need for a clear and thoughtful national research agenda that will yield the greatest benefit from today's limited resources. The committee makes its recommendations within the public health framework and incorporates diverse fields of inquiry and a range of policy positions. It examines both the demand and supply aspects of drug abuse. Pathways of Addiction offers a fact-filled, highly readable examination of drug abuse issues in the United States, describing findings and outlining research needs in the areas of behavioral and neurobiological foundations of drug abuse. The book covers the epidemiology and etiology of drug abuse and discusses several of its most troubling health and social consequences, including HIV, violence, and harm to children. Pathways of Addiction looks at the efficacy of different prevention interventions and the many advances that have been made in treatment research in the past 20 years. The book also examines drug treatment in the criminal justice setting and the effectiveness of drug treatment under managed care. The committee advocates systematic study of the laws by which the nation attempts to control drug use and identifies the research questions most germane to public policy. Pathways of Addiction provides a strategic outline for wise investment of the nation's research resources in drug abuse. This comprehensive and accessible volume will have widespread relevanceâ€"to policymakers, researchers, research administrators, foundation decisionmakers, healthcare professionals, faculty and students, and concerned individuals.


Theories on Drug Abuse

Theories on Drug Abuse
Author: National Institute on Drug Abuse. Division of Research
Publisher:
Total Pages: 534
Release: 1980
Genre: Drug abuse
ISBN:

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Methods in Drug Abuse Research

Methods in Drug Abuse Research
Author: Barry D. Waterhouse
Publisher: CRC Press
Total Pages: 298
Release: 2002-11-25
Genre: Medical
ISBN: 1420038680

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The field of drug addiction and substance abuse, which was initially confined to behavioral studies, has broadened dramatically. It now includes a vast array of cellular and molecular approaches as well as sophisticated electrophysiological and neurochemical methodologies that bridge the gap between cellular/molecular events and behavior. In many c


Pharmacokinetics and Pharmacodynamics of Abused Drugs

Pharmacokinetics and Pharmacodynamics of Abused Drugs
Author: MD, FFFLM, Steven B. Karch
Publisher: CRC Press
Total Pages: 208
Release: 2007-10-09
Genre: Law
ISBN: 1420054600

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Extracted from the Drug Abuse Handbook, 2nd edition, to give you just the information you need at an affordable price. Pharmacokinetics and Pharmacodynamics of Abused Drugs is a concise and focused volume devoted to the metabolism and measurable effects of drugs on the human body. Beginning with basic concepts and models