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Metallothioneins in Biochemistry and Pathology

Metallothioneins in Biochemistry and Pathology
Author: Paolo Zatta
Publisher: World Scientific
Total Pages: 335
Release: 2008
Genre: Medical
ISBN: 9812778934

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Metallothioneins (MTs) represent a large family of proteins characterized by high heavy metal content (mainly CuII and ZnII) and by an unusual cysteine abundance. They have a powerful protective function in all animal tissues, due most likely to their properties as free radical scavengers protecting against oxidative damage. Moreover, the presence and overexpression of MTs in various pathological conditions, such as metal dyshomeostasis, cell proliferation, neurological disorders, and chemotherapy and radiotherapy resistance, could be used as an important prognostic marker, as a histopathological diagnostic tool, and to follow specific pharmacological treatments.This important book explores the role of MTs in the field of neurological disorders (brain inflammation, Alzheimer's and prion diseases, autism, ALS, etc.), cardiology (cardiomyopathy, atherosclerosis), and oncology (melanoma, prostate and breast cancer), through authoritative contributions and a description of basic biochemical information and paradigmatic pathological events.


Metallothionein IV

Metallothionein IV
Author: C. Klaasen
Publisher: Birkhäuser
Total Pages: 641
Release: 2012-12-06
Genre: Science
ISBN: 3034888473

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The Proceedings of the Fourth International Metallothionein Meeting (MT-97) feature the latest research on metallothionein. The book covers a broad range of topics which provide important information for both basic and clinical investigators. The selected 94 articles in this book are written by the leading scientists in the field around the world. This is an increasingly important, multi-disciplinary area of study that has benefitted from recent advances in concepts and methodologies from other fields.


Metallothionein in Biology and Medicine

Metallothionein in Biology and Medicine
Author: Curtis D. Klaassen
Publisher: CRC Press
Total Pages: 436
Release: 1991-08-27
Genre: Medical
ISBN: 9780849388323

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This book brings together work from leading researchers to present the most recent advances in research on metallothionein. This protein interests toxicologists because it is thought that metallothionein protects against metal toxicity and possibly against oxidative stress. It is of interest to pharmacologists because modification of metallothionein levels might have a role in cancer chemotherapy. Nutritionists have an interest in this protein because it appears to be a major storage protein for zinc. Biochemists and molecular biologists will be interested in the mechanisms of regulation of this protein because it is extremely inducible.


Metallothioneins and Related Chelators

Metallothioneins and Related Chelators
Author: Astrid Sigel
Publisher: Walter de Gruyter GmbH & Co KG
Total Pages: 544
Release: 2015-07-24
Genre: Science
ISBN: 3110436272

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These sulfur-rich chelators, being important in metal ion homeostasis, find increasing attention. MILS-5, written by 30 internationally recognized experts, focuses on this hot topic. The reader is supported by about 20 tables, more than 80 illustrations and nearly 2000 references. This book is an essential resource for scientists working in a wide range of disciplines from environmental toxicology and inorganic biochemistry all the way through to physiology and medicine.


Metallothionein III

Metallothionein III
Author: Kazuo T. Suzuki
Publisher: Birkhauser
Total Pages: 504
Release: 1993
Genre: Medical
ISBN:

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Metallothionein IV

Metallothionein IV
Author: C Klaasen
Publisher:
Total Pages: 700
Release: 1998-12-01
Genre:
ISBN: 9783034888486

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Genetics, Neurology, Behavior, and Diet in Dementia

Genetics, Neurology, Behavior, and Diet in Dementia
Author: Colin R Martin
Publisher: Academic Press
Total Pages: 954
Release: 2020-08-11
Genre: Medical
ISBN: 0128158697

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Genetics, Neurology, Behavior, and Diet in Dementia: The Neuroscience of Dementia, Volume 2 consolidates different fields of dementia research into a single book, covering a range of subjects, including Alzheimer’s disease, Lewy body dementia, mixed dementia, vascular dementia, physical activity, risk factors, mortality, biomarkers, SPECT, CT, MRI, questionnaires, nutrition, sleep, delirium, hearing loss, agitation, aggression, delusions, anxiety, depression, hallucinations, psychosis, senile plaques, tau and amyloid-beta, neuroinflammation, and molecular biology. This foundational, comprehensive book assembles the latest understanding on all dementias and their common features in a single source. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field. Offers comprehensive coverage of a broad range of topics related to dementia Serves as a foundational collection for neuroscientists and neurologists on the biology of dementia and brain dysfunction Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Provides unique sections on specific subareas, intellectual components, and knowledge-based niches that will help readers navigate key areas for research and further clinical recommendations Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations Serves as a "one-stop" source for everything you need to know about dementia


Hydrolith 2: Surrealist Research & Investigations

Hydrolith 2: Surrealist Research & Investigations
Author: Oyster Moon Press
Publisher: Lulu.com
Total Pages: 370
Release: 2013-08-12
Genre: Poetry
ISBN: 0578157926

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Magazine. Poetry. Fiction. Literary Nonfiction. Art. Translation. "This second issue of HYDROLITH is a continuation of what the first volume started, which was and is to assemble a stimulating selection of exclusively recent work by groups and individuals of the international Surrealist movement, to facilitate intellectual exchange and collaboration, enabling us to concentrate the echoes of our commonalities as well as the shadows of our differences. In so doing, this volume aspires to reduce all manner of distances that exist between us. All works in this book are in English, while many of them are translations from the Dutch, French, Greek, Portuguese, Romanian, Spanish and Turkish languages."--from the Preface


Metallothioneins in Normal and Cancer Cells

Metallothioneins in Normal and Cancer Cells
Author: Piotr Dziegiel
Publisher: Springer
Total Pages: 117
Release: 2016-02-16
Genre: Science
ISBN: 9783319274713

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This book describes the structures of Metallothionein (MT) family members and the cellular functions of MT-1, MT-2 and MT-4 isoforms, as well as provides insights into divergent biological roles of MT-3. The authors explain the involvement of MT molecules in various processes related to carcinogenesis, including an organ-specific presentation of current data concerning their potential impact on the progression of various tumors and the regulatory role of MT family members in the function of the immune system.