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Metallothionein IV

Metallothionein IV
Author: C. Klaasen
Publisher: Birkhäuser
Total Pages: 641
Release: 2012-12-06
Genre: Science
ISBN: 3034888473

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The Proceedings of the Fourth International Metallothionein Meeting (MT-97) feature the latest research on metallothionein. The book covers a broad range of topics which provide important information for both basic and clinical investigators. The selected 94 articles in this book are written by the leading scientists in the field around the world. This is an increasingly important, multi-disciplinary area of study that has benefitted from recent advances in concepts and methodologies from other fields.


Lead: Its Effects on Environment and Health

Lead: Its Effects on Environment and Health
Author: Astrid Sigel
Publisher: Walter de Gruyter GmbH & Co KG
Total Pages: 596
Release: 2017-04-10
Genre: Science
ISBN: 3110434334

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Volume 17, entitled Lead: Its Effects on Environment and Health of the series Metal Ions in Life Sciences centers on the interrelations between biosystems and lead. The book provides an up-to-date review of the bioinorganic chemistry of this metal and its ions; it covers the biogeochemistry of lead, its use (not only as gasoline additive) and anthropogenic release into the environment, its cycling and speciation in the atmosphere, in waters, soils, and sediments, and also in mammalian organs. The analytical tools to determine and to quantify this toxic element in blood, saliva, urine, hair, etc. are described. The properties of lead(II) complexes formed with amino acids, peptides, proteins (including metallothioneins), nucleobases, nucleotides, nucleic acids, and other ligands of biological relevance are summarized for the solid state and for aqueous solutions as well. All this is important for obtaining a coherent picture on the properties of lead, its effects on plants and toxic actions on mammalian organs. This and more is treated in an authoritative and timely manner in the 16 stimulating chapters of Volume 17, which are written by 36 internationally recognized experts from 13 nations. The impact of this recently again vibrant research area is manifested in nearly 2000 references, over 50 tables and more than 100 illustrations (half in color). Lead: Its Effects on Environment and Health is an essential resource for scientists working in the wide range from material sciences, inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that it also provides excellent information for teaching.


Metallothioneins in Biochemistry and Pathology

Metallothioneins in Biochemistry and Pathology
Author: Paolo Zatta
Publisher: World Scientific
Total Pages: 335
Release: 2008
Genre: Medical
ISBN: 9812778934

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Metallothioneins (MTs) represent a large family of proteins characterized by high heavy metal content (mainly CuII and ZnII) and by an unusual cysteine abundance. They have a powerful protective function in all animal tissues, due most likely to their properties as free radical scavengers protecting against oxidative damage. Moreover, the presence and overexpression of MTs in various pathological conditions, such as metal dyshomeostasis, cell proliferation, neurological disorders, and chemotherapy and radiotherapy resistance, could be used as an important prognostic marker, as a histopathological diagnostic tool, and to follow specific pharmacological treatments.This important book explores the role of MTs in the field of neurological disorders (brain inflammation, Alzheimer's and prion diseases, autism, ALS, etc.), cardiology (cardiomyopathy, atherosclerosis), and oncology (melanoma, prostate and breast cancer), through authoritative contributions and a description of basic biochemical information and paradigmatic pathological events.


Metallothioneins in Normal and Cancer Cells

Metallothioneins in Normal and Cancer Cells
Author: Piotr Dziegiel
Publisher: Springer
Total Pages: 126
Release: 2016-02-04
Genre: Science
ISBN: 3319274724

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This book describes the structures of Metallothionein (MT) family members and the cellular functions of MT-1, MT-2 and MT-4 isoforms, as well as provides insights into divergent biological roles of MT-3. The authors explain the involvement of MT molecules in various processes related to carcinogenesis, including an organ-specific presentation of current data concerning their potential impact on the progression of various tumors and the regulatory role of MT family members in the function of the immune system.


Metallothioneins and Related Chelators

Metallothioneins and Related Chelators
Author: Astrid Sigel
Publisher: Walter de Gruyter GmbH & Co KG
Total Pages: 544
Release: 2015-07-24
Genre: Science
ISBN: 3110436272

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These sulfur-rich chelators, being important in metal ion homeostasis, find increasing attention. MILS-5, written by 30 internationally recognized experts, focuses on this hot topic. The reader is supported by about 20 tables, more than 80 illustrations and nearly 2000 references. This book is an essential resource for scientists working in a wide range of disciplines from environmental toxicology and inorganic biochemistry all the way through to physiology and medicine.


Metallothioneins in Biochemistry and Pathology

Metallothioneins in Biochemistry and Pathology
Author: Paolo Zatta
Publisher: World Scientific
Total Pages: 335
Release: 2008
Genre: Science
ISBN: 9812778942

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Metallothioneins (MTs) represent a large family of proteins characterized by high heavy metal content (mainly CuII and ZnII) and by an unusual cysteine abundance. They have a powerful protective function in all animal tissues, due most likely to their properties as free radical scavengers protecting against oxidative damage. Moreover, the presence and overexpression of MTs in various pathological conditions, such as metal dyshomeostasis, cell proliferation, neurological disorders, and chemotherapy and radiotherapy resistance, could be used as an important prognostic marker, as a histopathological diagnostic tool, and to follow specific pharmacological treatments.This important book explores the role of MTs in the field of neurological disorders (brain inflammation, Alzheimer's and prion diseases, autism, ALS, etc.), cardiology (cardiomyopathy, atherosclerosis), and oncology (melanoma, prostate and breast cancer), through authoritative contributions and a description of basic biochemical information and paradigmatic pathological events.


Handbook on the Toxicology of Metals: Specific metals

Handbook on the Toxicology of Metals: Specific metals
Author: Lars Friberg
Publisher: Elsevier Science & Technology
Total Pages: 758
Release: 1986
Genre: Medical
ISBN:

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Chapters on specific metals include physical and chemical properties, methods and problems of analysis, production and uses, environmental levels and exposures, metabolism, levels in tissues and biological fluids, effects and dose-response relationships, carcinogenicity, mutagenicity, teratogenicity and preventative measures, diagnosis, treatment and prognosis.


Plant Metal Interaction

Plant Metal Interaction
Author: Parvaiz Ahmad
Publisher: Elsevier
Total Pages: 654
Release: 2016-02-02
Genre: Technology & Engineering
ISBN: 0128031832

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Plant Metal Interaction: Emerging Remediation Techniques covers different heavy metals and their effect on soils and plants, along with the remediation techniques currently available. As cultivable land is declining day-by-day as a result of increased metals in our soil and water, there is an urgent need to remediate these effects. This multi-contributed book is divided into four sections covering the whole of plant metal interactions, including heavy metals, approaches to alleviate heavy metal stress, microbial approaches to remove heavy metals, and phytoremediation. Provides an overview of the effect of different heavy metals on growth, biochemical reactions, and physiology of various plants Serves as a reference guide for available techniques, challenges, and possible solutions in heavy metal remediation Covers sustainable technologies in uptake and removal of heavy metals


Sulphur in Plants

Sulphur in Plants
Author: Y.P. Abrol
Publisher: Springer Science & Business Media
Total Pages: 424
Release: 2013-06-29
Genre: Science
ISBN: 9401702896

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Sulphur (S) plays a pivotal role in various plant growth and development processes being a constituent of sulphur-containing amino acids, cysteine and methionine, and other metabolites viz., glutathione and phytochelatins, co-factor of enzymes which contribute to stress repair and amelioration of heavy metal toxicity. Besides, a number of S-containing components are biologically active and, thus, a source for use as medicinal value. The basic global issue before the agricultural scientist and world community is to evolve cultivars and develop methodologies for efficient use of inputs to enhance agricultural productivity. This is particularly true of the developing countries which are going to see maximum rise in population with changing food demands and declining availability of land. Amongst the inputs, nutrients play a crucial role. The major requirement is for N, P and K followed by several micro-nutrients. In this context reports of world-wide S deficiency in the agricultural systems are relevant. The reasons are many. Broadly speaking reduction inS emission, use of S-free N, P and K fertilizers and higher biomass production contributed the maximum. Despite the need for sulphur as an essential plant nutrient and the substantial returns expected from its use, very little attention has been given to fill the gap between supply and demand of S.


Metallothionein II

Metallothionein II
Author: J.H. Kägi
Publisher: Birkhäuser
Total Pages: 723
Release: 2014-03-27
Genre: Science
ISBN: 3034867840

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