Mechanisms Of Airway Remodelling PDF Download
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Author | : Peter Howarth |
Publisher | : CRC Press |
Total Pages | : 328 |
Release | : 2001 |
Genre | : MEDICAL |
ISBN | : 9780429132582 |
Download Airway Remodeling Book in PDF, ePub and Kindle
This landmark volume discusses the characteristics and impact of the remodeling process on airway function and clinical disease expression within the airway in asthma, covering pharmacological therapies and possible future targets relevant to regulating the remodeling process. Emphasizes the importance of treating underlying airway inflammation and the relevance of structural alterations to the airway wall, including glandular increases, enhanced collagen deposition within the submucosa, increased vasculature, smooth hypertrophy, and hyperplasias! Tracing the development and maintenance of bronchial hyperresponsiveness, decline in lung function, and loss of reversibility evident in chronic asthma, Airway Remodelingdescribes the contribution of inflammatory cells in the development of airway structural changes examines how pharmaceutical agents act and whether existing treatments modify or prevent remodeling in chronically inflamed asthmatic airways considers whether neural pathways initiate as well as contribute to the airway inflammatory cascade that leads to remodeling reviews the action of cytokines and growth factors on ASM signaling outlines novel approaches to regulating smooth muscle growth clarifies whether permanent ventilatory incapacity in asthma is caused by the uncoupling of the airway and the role of the lung parenchyma details high-resolution computerized tomography scan to measure the internal size of the airway at baseline, during challenge, or after bronchodilatation and more!Improving lung function and quality of life by reducing the need for emergency care, hospital admissions, and systemic steroid administration, Airway Remodeling is a superb reference for pulmonologists and respiratory system specialists; physiologists; pneumologists; allergists; pharmacologists; molecular, cellular, and lung biologists; and graduate and medical school students in these disciplines.
Author | : Boehringer Ingelheim Pharmaceuticals |
Publisher | : |
Total Pages | : |
Release | : 2001 |
Genre | : |
ISBN | : |
Download Mechanisms of Airway Remodeling Book in PDF, ePub and Kindle
Author | : Sarah Boustany |
Publisher | : |
Total Pages | : 364 |
Release | : 2008 |
Genre | : Airway (Medicine) |
ISBN | : |
Download Mechanisms of Airway Remodelling Book in PDF, ePub and Kindle
Author | : |
Publisher | : |
Total Pages | : 94 |
Release | : 2001 |
Genre | : |
ISBN | : |
Download Mechanisms of Airway Remodeling Book in PDF, ePub and Kindle
Author | : Lilly Quan |
Publisher | : |
Total Pages | : 524 |
Release | : 2004 |
Genre | : Asthma |
ISBN | : |
Download Mechanisms of Airway Wall Remodelling Book in PDF, ePub and Kindle
Author | : Peter J. Barnes |
Publisher | : Elsevier |
Total Pages | : 897 |
Release | : 2009-03-19 |
Genre | : Medical |
ISBN | : 0080920608 |
Download Asthma and COPD Book in PDF, ePub and Kindle
The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments. * Each chapter considers Asthma and COPD in side-by-side contrast and comparison – not in isolation - in the context of mechanism, triggers, assessments, therapies, and clinical management * Presents the latest and most comprehensive understandings of the mechanisms of inflammation in both Asthma and COPD * Most extensive reference to primary literature on both Asthma and COPD in one source. * Easy-to-read summaries of the latest advances alongside clear illustrations
Author | : A. G. Stewart |
Publisher | : CRC Press |
Total Pages | : 371 |
Release | : 2020-10-28 |
Genre | : Medical |
ISBN | : 1000099040 |
Download Airway Wall Remodelling in Asthma Book in PDF, ePub and Kindle
Asthma is a disease of high prevalence that has shown a trend toward increasing incidence, morbidity, and mortality over the last three decades despite apparently effective drug treatments and increasing awareness of the need for better disease management. Often the inflammatory component of asthma is studied; however, the tissue remodelling process is a significant process that should not be overlooked. This valuable reference synthesizes current data and concepts developed to determine the relationship between airway wall remodelling and the pathogenesis of asthma. It discusses evidence for structural changes in asthmatic airway, the relationship between airway thickening and hyperresponsiveness, the relationship between cytokine production and tissue remodelling and inflammation, the significance of epithelial changes and the extracellular matrix, and in vivo and in vitro experimental approaches to the assessment of remodelling. Pharmacological and biochemical mechanisms that control cell proliferation are also examined. The consequences of airway wall remodelling for airway hyperresponsiveness is the unique focus of this volume, offering a fresh perspective of advances in asthma research.
Author | : G Dave Singh |
Publisher | : World Scientific |
Total Pages | : 474 |
Release | : 2021-03-05 |
Genre | : Medical |
ISBN | : 9811225362 |
Download Pneumopedics And Craniofacial Epigenetics: Biomimetic Oral Appliance Therapy For Pediatric And Adult Sleep Disordered Breathing Book in PDF, ePub and Kindle
This textbook provides a comprehensive introduction to the novel concepts of pneumopedics and craniofacial epigenetics. Clinically, these mechanisms are delivered through biomimetic oral appliance therapy. The text, therefore, covers both genetics and epigenetics of craniofacial development, as well as growth and development of the craniofacial architecture. Despite being complex subjects, the style of writing allows the general reader to assimilate this information and sets the scene for how these principles might best be utilized. For example, the clinical application of biomimetic tooth movement achieved through epigenetic orthodontics is presented. Prior to pneumopedic treatment, the significance of craniofacial diagnostics and treatment planning is discussed, before detailing the principles of designing a biomimetic oral appliance. Next, the book goes over the practicalities of clinical adjustments of oral biomimetic devices. Moving onto patient selection and management, the book also provides an overview and introduction to pediatric craniofacial epigenetics, which touches upon the preventive aspects of healthcare, including nutrition. This section is followed by an introduction to sleep and sleep disordered breathing in both children and adults, which includes a comprehensive approach to the potential elimination of obstructive sleep apnea. Finally, clinical biomimetic correction is illustrated with examples of non-surgical upper airway remodeling using various cases. The book also contains a Glossary containing definitions of common terms as well as an Appendix of documents that might be useful for both implementation and further study.
Author | : Kian Fan Chung |
Publisher | : John Wiley & Sons |
Total Pages | : 326 |
Release | : 2008-04-30 |
Genre | : Science |
ISBN | : 0470754214 |
Download Airway Smooth Muscle in Asthma and COPD Book in PDF, ePub and Kindle
In this book, leading researchers in medicine and molecular pharmacology explain the cellular mechanisms that control airway smooth muscle. The means by which these are disrupted in disease, and the pharmacologic strategies by which they may be modified are discussed and future therapeutic interventions are identified. Aimed at specialists in pulmonology, this volume provides the clinician with the most up to date information on one of the core physiological processes in airway disease, and offers insights into current and future approaches to management. Authoritative update on key mechanisms of airway constriction in Asthma and COPD Relates latest research to bronchodilator therapy Multi-contributed text, co-coordinated by two of the leading authorities in the field.
Author | : Peter H. Howarth |
Publisher | : CRC Press |
Total Pages | : 328 |
Release | : 2001-01-16 |
Genre | : Medical |
ISBN | : 9780824704483 |
Download Airway Remodeling Book in PDF, ePub and Kindle
This landmark volume discusses the characteristics and impact of the remodeling process on airway function and clinical disease expression within the airway in asthma, covering pharmacological therapies and possible future targets relevant to regulating the remodeling process. Emphasizes the importance of treating underlying airway inflammation and the relevance of structural alterations to the airway wall, including glandular increases, enhanced collagen deposition within the submucosa, increased vasculature, smooth hypertrophy, and hyperplasias! Tracing the development and maintenance of bronchial hyperresponsiveness, decline in lung function, and loss of reversibility evident in chronic asthma, Airway Remodeling describes the contribution of inflammatory cells in the development of airway structural changes examines how pharmaceutical agents act and whether existing treatments modify or prevent remodeling in chronically inflamed asthmatic airways considers whether neural pathways initiate as well as contribute to the airway inflammatory cascade that leads to remodeling reviews the action of cytokines and growth factors on ASM signaling outlines novel approaches to regulating smooth muscle growth clarifies whether permanent ventilatory incapacity in asthma is caused by the uncoupling of the airway and the role of the lung parenchyma details high-resolution computerized tomography scan to measure the internal size of the airway at baseline, during challenge, or after bronchodilatation and more! Improving lung function and quality of life by reducing the need for emergency care, hospital admissions, and systemic steroid administration, Airway Remodeling is a superb reference for pulmonologists and respiratory system specialists; physiologists; pneumologists; allergists; pharmacologists; molecular, cellular, and lung biologists; and graduate and medical school students in these disciplines.