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Measurement Technologies for up- and Downstream Bioprocessing

Measurement Technologies for up- and Downstream Bioprocessing
Author: Carl-Fredrik Mandenius
Publisher: MDPI
Total Pages: 160
Release: 2021-09-01
Genre: Science
ISBN: 3036511504

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This book is devoted to new developments in measurement technologies for upstream and downstream bioprocessing. The recent advances in biotechnology and bioprocessing have generated a number of new biological products that require more qualified analytical technologies for diverse process analytical needs. These includes especially fast and sensitive measurement technology that, early in the process train, can inform on critical process parameters related to process economy and product quality and that can facilitate ambitions of designing efficient integrated end-to-end bioprocesses. This book covers these topics as well as analytical monitoring methods based either on real-time or in-line sensor technology, on simple and compact bioanalytical devices, or on the use of advanced data prediction methods.


Measurement Technologies for Up- and Downstream Bioprocessing

Measurement Technologies for Up- and Downstream Bioprocessing
Author: Carl-Fredrik Mandenius
Publisher:
Total Pages: 160
Release: 2021
Genre:
ISBN: 9783036511511

Download Measurement Technologies for Up- and Downstream Bioprocessing Book in PDF, ePub and Kindle

This book is devoted to new developments in measurement technologies for upstream and downstream bioprocessing. The recent advances in biotechnology and bioprocessing have generated a number of new biological products that require more qualified analytical technologies for diverse process analytical needs. These includes especially fast and sensitive measurement technology that, early in the process train, can inform on critical process parameters related to process economy and product quality and that can facilitate ambitions of designing efficient integrated end-to-end bioprocesses. This book covers these topics as well as analytical monitoring methods based either on real-time or in-line sensor technology, on simple and compact bioanalytical devices, or on the use of advanced data prediction methods.


Biopharmaceutical Processing

Biopharmaceutical Processing
Author: Gunter Jagschies
Publisher: Elsevier
Total Pages: 1310
Release: 2018-01-18
Genre: Technology & Engineering
ISBN: 0128125527

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Biopharmaceutical Processing: Development, Design, and Implementation of Manufacturing Processes covers bioprocessing from cell line development to bulk drug substances. The methods and strategies described are essential learning for every scientist, engineer or manager in the biopharmaceutical and vaccines industry. The integrity of the bioprocess ultimately determines the quality of the product in the biotherapeutics arena, and this book covers every stage including all technologies related to downstream purification and upstream processing fields. Economic considerations are included throughout, with recommendations for lowering costs and improving efficiencies. Designed for quick reference and easy accessibility of facts, calculations and guidelines, this book is an essential tool for industrial scientists and managers in the biopharmaceutical industry. Offers a comprehensive, go-to reference for daily work decisions Covers both upstream and downstream processes Includes case studies that emphasize financial outcomes Presents summaries, decision grids, graphs and overviews for quick reference


Measurement, Monitoring, Modelling and Control of Bioprocesses

Measurement, Monitoring, Modelling and Control of Bioprocesses
Author: Carl-Fredrik Mandenius
Publisher: Springer
Total Pages: 288
Release: 2014-07-08
Genre: Science
ISBN: 3642368387

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Automated Measurement and Monitoring of Bioprocesses: Key Elements of the M3C Strategy, by Bernhard Sonnleitner Automatic Control of Bioprocesses, by Marc Stanke, Bernd Hitzmann An Advanced Monitoring Platform for Rational Design of Recombinant Processes, by G. Striedner, K. Bayer Modelling Approaches for Bio-Manufacturing Operations, by Sunil Chhatre Extreme Scale-Down Approaches for Rapid Chromatography Column Design and Scale-Up During Bioprocess Development, by Sunil Chhatre Applying Mechanistic Models in Bioprocess Development, by Rita Lencastre Fernandes, Vijaya Krishna Bodla, Magnus Carlquist, Anna-Lena Heins, Anna Eliasson Lantz, Gürkan Sin and Krist V. Gernaey Multivariate Data Analysis for Advancing the Interpretation of Bioprocess Measurement and Monitoring Data, by Jarka Glassey Design of Pathway-Level Bioprocess Monitoring and Control Strategies Supported by Metabolic Networks, by Inês A. Isidro, Ana R. Ferreira, João J. Clemente, António E. Cunha, João M. L. Dias, Rui Oliveira Knowledge Management and Process Monitoring of Pharmaceutical Processes in the Quality by Design Paradigm, by Anurag S Rathore, Anshuman Bansal, Jaspinder Hans The Choice of Suitable Online Analytical Techniques and Data Processing for Monitoring of Bioprocesses, by Ian Marison, Siobhán Hennessy, Róisín Foley, Moira Schuler, Senthilkumar Sivaprakasam, Brian Freeland


Departments of Commerce, Justice, and State, the Judiciary, and Related Agencies Appropriations for 1996: Justification of the budget estimates, Department of Commerce

Departments of Commerce, Justice, and State, the Judiciary, and Related Agencies Appropriations for 1996: Justification of the budget estimates, Department of Commerce
Author: United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Commerce, Justice, and State, the Judiciary, and Related Agencies
Publisher:
Total Pages: 1954
Release: 1995
Genre: Budget
ISBN:

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Encyclopedia of Agricultural, Food, and Biological Engineering

Encyclopedia of Agricultural, Food, and Biological Engineering
Author: Dennis R. Heldman
Publisher: CRC Press
Total Pages: 2001
Release: 2010-10-21
Genre: Science
ISBN: 1498711073

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Examining the role of engineering in delivery of quality consumer products, this expansive resource covers the development and design of procedures, equipment, and systems utilized in the production and conversion of raw materials into food and nonfood consumer goods. With nearly 2000 photographs, figures, tables, and equations including 128 color figures the book emphasizes and illustrates the various engineering processes associated with the production of materials with agricultural origin. With contributions from more than 350 experts and featuring more than 200 entries and 3600 references, this is the largest and most comprehensive guide on raw production technology.


Bioprocess Technology

Bioprocess Technology
Author: Anton Moser
Publisher: Springer Science & Business Media
Total Pages: 480
Release: 2012-12-06
Genre: Science
ISBN: 1461387485

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This book is based on a 1981 German language edition published by Springer Verlag, Vienna, under the title Bioprozesstechnik. Philip Manor has done the translation, for which I am deeply grateful. This book differs from the German edition in many ways besides language. It is substantially enlargened and updated, and examples of computer simula tions have been added together with other appendices to make the work both more comprehensive and more practical. This book is the result of over 15 years of experience in teaching and research. It stems from lectures that I began in 1970 at the Technical University of Graz, Austria, and continued at the University of Western Ontario in London, Canada, 1980; at the Free University of Brussels, 1981; at Chalmers Technical University in G6teborg, Sweden; at the Academy of Sciences in lena, East Germany; at the "Haus der Technik" in Essen, West Germany, 1982; at the Academy of Science in Sofia, Bulgaria; and at the Technical University of Delft, Netherlands, 1986. The main goals of this book are, first, to bridge the gap that always exists between basic principles and applied engineering practice, second, to enhance the integration between biological and physical phenomena, and, third, to contribute to the internal development of the field of biotechnology by describing the process-oriented field of bioprocess technology.


Continuous Biomanufacturing

Continuous Biomanufacturing
Author: Ganapathy Subramanian
Publisher: John Wiley & Sons
Total Pages: 628
Release: 2017-12-26
Genre: Science
ISBN: 3527340637

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This is the most comprehensive treatise of this topic available, providing invaluable information on the technological and economic benefits to be gained from implementing continuous processes in the biopharmaceutical industry. Top experts from industry and academia cover the latest technical developments in the field, describing the use of single-use technologies alongside perfusion production platforms and downstream operations. Special emphasis is given to process control and monitoring, including such topics as 'quality by design' and automation. The book is supplemented by case studies that highlight the enormous potential of continuous manufacturing for biopharmaceutical production facilities.