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| Author | : Vincent C. Rideout |
| Publisher | : |
| Total Pages | : 296 |
| Release | : 1991 |
| Genre | : Medical |
| ISBN | : |
| Author | : Claudio Cobelli |
| Publisher | : Academic Press |
| Total Pages | : 384 |
| Release | : 2019-08-01 |
| Genre | : Computers |
| ISBN | : 0128158050 |
Introduction to Modeling in Physiology and Medicine, Second Edition, develops a clear understanding of the fundamental principles of good modeling methodology. Sections show how to create valid mathematical models that are fit for a range of purposes. These models are supported by detailed explanation, extensive case studies, examples and applications. This updated edition includes clearer guidance on the mathematical prerequisites needed to achieve the maximum benefit from the material, a greater detail regarding basic approaches to modeling, and discussions on non-linear and stochastic modeling. The range of case study material has been substantially extended, with examples drawn from recent research experience. Key examples include a cellular model of insulin secretion and its extension to the whole-body level, a model of insulin action during a meal/oral glucose tolerance test, a large-scale simulation model of type 1 diabetes and its use in in silico clinical trials and drug trials. Covers the underlying principles of good quantitative modeling methodology, with applied biomedical engineering and bioscience examples to ensure relevance to students, current research and clinical practice Includes modeling data, modeling systems, linear and non-linear systems, model identification, parametric and non-parametric models, and model validation Presents clear, step-by-step working plus examples and extensive case studies that relate concepts to real world applications Provides end-of-chapter exercises and assignments to reinforce learning
| Author | : Claudio Cobelli |
| Publisher | : Elsevier |
| Total Pages | : 337 |
| Release | : 2008-02-06 |
| Genre | : Technology & Engineering |
| ISBN | : 0080559980 |
This unified modeling textbook for students of biomedical engineering provides a complete course text on the foundations, theory and practice of modeling and simulation in physiology and medicine. It is dedicated to the needs of biomedical engineering and clinical students, supported by applied BME applications and examples. Developed for biomedical engineering and related courses: speaks to BME students at a level and in a language appropriate to their needs, with an interdisciplinary clinical/engineering approach, quantitative basis, and many applied examples to enhance learning Delivers a quantitative approach to modeling and also covers simulation: the perfect foundation text for studies across BME and medicine Extensive case studies and engineering applications from BME, plus end-of-chapter exercises
| Author | : Jerry J. Batzel |
| Publisher | : Springer |
| Total Pages | : 270 |
| Release | : 2012-12-14 |
| Genre | : Mathematics |
| ISBN | : 3642328822 |
This volume synthesizes theoretical and practical aspects of both the mathematical and life science viewpoints needed for modeling of the cardiovascular-respiratory system specifically and physiological systems generally. Theoretical points include model design, model complexity and validation in the light of available data, as well as control theory approaches to feedback delay and Kalman filter applications to parameter identification. State of the art approaches using parameter sensitivity are discussed for enhancing model identifiability through joint analysis of model structure and data. Practical examples illustrate model development at various levels of complexity based on given physiological information. The sensitivity-based approaches for examining model identifiability are illustrated by means of specific modeling examples. The themes presented address the current problem of patient-specific model adaptation in the clinical setting, where data is typically limited.
| Author | : Johnny T. Ottesen |
| Publisher | : SIAM |
| Total Pages | : 311 |
| Release | : 2004-01-01 |
| Genre | : Medical |
| ISBN | : 9780898718287 |
This book introduces mathematicians to real applications from physiology. Using mathematics to analyze physiological systems, the authors focus on models reflecting current research in cardiovascular and pulmonary physiology. In particular, they present models describing blood flow in the heart and the cardiovascular system, as well as the transport of oxygen and carbon dioxide through the respiratory system and a model for baroreceptor regulation.
| Author | : Professor Vasilis Z. Marmarelis |
| Publisher | : John Wiley & Sons |
| Total Pages | : 564 |
| Release | : 2004-09-03 |
| Genre | : Medical |
| ISBN | : 9780471469605 |
The study of nonlinearities in physiology has been hindered by the lack of effective ways to obtain nonlinear dynamic models from stimulus-response data in a practical context. A considerable body of knowledge has accumulated over the last thirty years in this area of research. This book summarizes that progress, and details the most recent methodologies that offer practical solutions to this daunting problem. Implementation and application are discussed, and examples are provided using both synthetic and actual experimental data. This essential study of nonlinearities in physiology apprises researchers and students of the latest findings and techniques in the field.
| Author | : Suresh R. Devasahayam |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 348 |
| Release | : 2012-12-06 |
| Genre | : Technology & Engineering |
| ISBN | : 1461542995 |
In the past few years Biomedical Engineering has received a great deal of attention as one of the emerging technologies in the last decade and for years to come, as witnessed by the many books, conferences, and their proceedings. Media attention, due to the applications-oriented advances in Biomedical Engineering, has also increased. Much of the excitement comes from the fact that technology is rapidly changing and new technological adventures become available and feasible every day. For many years the physical sciences contributed to medicine in the form of expertise in radiology and slow but steady contributions to other more diverse fields, such as computers in surgery and diagnosis, neurology, cardiology, vision and visual prosthesis, audition and hearing aids, artificial limbs, biomechanics, and biomaterials. The list goes on. It is therefore hard for a person unfamiliar with a subject to separate the substance from the hype. Many of the applications of Biomedical Engineering are rather complex and difficult to understand even by the not so novice in the field. Much of the hardware and software tools available are either too simplistic to be useful or too complicated to be understood and applied. In addition, the lack of a common language between engineers and computer scientists and their counterparts in the medical profession, sometimes becomes a barrier to progress.
| Author | : Suresh R. Devasahayam |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 395 |
| Release | : 2012-11-08 |
| Genre | : Technology & Engineering |
| ISBN | : 1461453321 |
The use of digital signal processing is ubiquitous in the field of physiology and biomedical engineering. The application of such mathematical and computational tools requires a formal or explicit understanding of physiology. Formal models and analytical techniques are interlinked in physiology as in any other field. This book takes a unitary approach to physiological systems, beginning with signal measurement and acquisition, followed by signal processing, linear systems modelling, and computer simulations. The signal processing techniques range across filtering, spectral analysis and wavelet analysis. Emphasis is placed on fundamental understanding of the concepts as well as solving numerical problems. Graphs and analogies are used extensively to supplement the mathematics. Detailed models of nerve and muscle at the cellular and systemic levels provide examples for the mathematical methods and computer simulations. Several of the models are sufficiently sophisticated to be of value in understanding real world issues like neuromuscular disease. This second edition features expanded problem sets and a link to extra downloadable material.
| Author | : Ewart Carson |
| Publisher | : Newnes |
| Total Pages | : 589 |
| Release | : 2013-12-05 |
| Genre | : Technology & Engineering |
| ISBN | : 0124095259 |
Modelling Methodology for Physiology and Medicine, Second Edition, offers a unique approach and an unprecedented range of coverage of the state-of-the-art, advanced modeling methodology that is widely applicable to physiology and medicine. The second edition, which is completely updated and expanded, opens with a clear and integrated treatment of advanced methodology for developing mathematical models of physiology and medical systems. Readers are then shown how to apply this methodology beneficially to real-world problems in physiology and medicine, such as circulation and respiration. The focus of Modelling Methodology for Physiology and Medicine, Second Edition, is the methodology that underpins good modeling practice. It builds upon the idea of an integrated methodology for the development and testing of mathematical models. It covers many specific areas of methodology in which important advances have taken place over recent years and illustrates the application of good methodological practice in key areas of physiology and medicine. It builds on work that the editors have carried out over the past 30 years, working in cooperation with leading practitioners in the field. Builds upon and enhances the reader's existing knowledge of modeling methodology and practice Editors are internationally renowned leaders in their respective fields Provides an understanding of modeling methodologies that can address real problems in physiology and medicine and achieve results that are beneficial either in advancing research or in providing solutions to clinical problems
| Author | : Jocelyne Troccaz |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 860 |
| Release | : 1997-03-05 |
| Genre | : Computers |
| ISBN | : 9783540627340 |
This book constitutes the refereed proceedings of the First Joint Conference; Computer Vision, Virtual Reality and Robotics in Medicine, CVRMed, and Medical Robotics and Computer-Assisted Surgery, MRCAS, held in Grenoble, France, in March 1997. The volume presents 76 regular revised papers and 16 clinical papers selected from a total of 161 submitted full papers. The volume offers highly innovative and promising research results in computer-assisted medicine and medical informatics. Among the areas covered are medical imaging, virtual reality, medical robotics, and computer-integrated therapy and surgery. The book is of relevance to clinicians, medical engineers, and computer scientists.
