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Many Pathways for Discovery

Many Pathways for Discovery
Author: Casey A. Mullin
Publisher: A-R Editions, Inc.
Total Pages: 164
Release:
Genre: Language Arts & Disciplines
ISBN: 0895799111

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Many Pathways for Discovery is a manual for metadata practitioners learning music cataloging for the first time, as well as a ready reference tool for more experienced practitioners. It is intended to serve as a companion guide to general music cataloging instruction, focusing on what has traditionally been considered the more advanced skillset of “subject analysis.” It provides guidance for answering the “W-questions” about music content: What is it? (genre/form); What is it for, or, How is it performed? (medium of performance); Who is it by and Who is it for? (demographic aspects); When was it created? (chronological aspects); Where was it created? (geographic aspects) This book is primarily geared toward a metadata environment based on MARC 21 encoding and on vocabularies developed by the Library of Congress, namely, the Medium of Performance Thesaurus for Music (LCMPT), the Genre/Form Terms for Library and Archival Materials (LCGFT), and the Demographic Group Terms (LCDGT). Comparisons to legacy practices involving Library of Congress Subject Headings (LCSH) are included. Additional chapters address encoding of faceted descriptors in Linked Data environments, and on discovery possibilities for end users. A bibliography of foundational and supplemental resources is provided.


Childhood

Childhood
Author: Sheldon White
Publisher:
Total Pages: 132
Release: 1980
Genre: Child development
ISBN:

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Pathway Analysis for Drug Discovery

Pathway Analysis for Drug Discovery
Author: Anton Yuryev
Publisher: John Wiley & Sons
Total Pages: 332
Release: 2008-09-17
Genre: Science
ISBN: 0470399260

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This book introduces drug researchers to the novel computational approaches of pathway analysis and explains the existing applications that can save time and money in the drug discovery process. It covers traditional computational methods and software for pathway analysis microarray, proteomics, and metabolomics. It explains pathway reconstruction of diseases and toxic states, pathway analysis in various phases, dynamic modeling of drug responses, and more. This is a core resource for drug discovery and pharmaceutical industry researchers, chemists, and biologists and for professionals in related fields.


Pathways to Discovery in Astronomy and Astrophysics for the 2020s

Pathways to Discovery in Astronomy and Astrophysics for the 2020s
Author: National Academies of Sciences, Engineering, and Medicine
Publisher:
Total Pages: 615
Release: 2022-08-04
Genre: Science
ISBN: 9780309467346

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The steering committee was specifically asked to (1) provide an overview of the current state of astronomy and astrophysics science, and technology research in support of that science, with connections to other scientific areas where appropriate; (2) identify the most compelling science challenges and frontiers in astronomy and astrophysics, which shall motivate the committee’s strategy for the future; (3) develop a comprehensive research strategy to advance the frontiers of astronomy and astrophysics for the period 2022-2032 that will include identifying, recommending, and ranking the highest-priority research activities; (4) utilize and recommend decision rules, where appropriate, that can accommodate significant but reasonable deviations in the projected budget or changes in urgency precipitated by new discoveries or unanticipated competitive activities; (5) assess the state of the profession, including workforce and demographic issues in the field, identify areas of concern and importance to the community, and where possible, provide specific, actionable, and practical recommendations to the agencies and community to address these areas. This report proposes a broad, integrated plan for space- and ground-based astronomy and astrophysics for the decade 2023-2032. It also lays the foundations for further advances in the following decade.


Data Mining in Drug Discovery

Data Mining in Drug Discovery
Author: Rémy D. Hoffmann
Publisher: John Wiley & Sons
Total Pages: 322
Release: 2013-09-25
Genre: Medical
ISBN: 3527656006

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Written for drug developers rather than computer scientists, this monograph adopts a systematic approach to mining scientifi c data sources, covering all key steps in rational drug discovery, from compound screening to lead compound selection and personalized medicine. Clearly divided into four sections, the first part discusses the different data sources available, both commercial and non-commercial, while the next section looks at the role and value of data mining in drug discovery. The third part compares the most common applications and strategies for polypharmacology, where data mining can substantially enhance the research effort. The final section of the book is devoted to systems biology approaches for compound testing. Throughout the book, industrial and academic drug discovery strategies are addressed, with contributors coming from both areas, enabling an informed decision on when and which data mining tools to use for one's own drug discovery project.


Systems Biology in Cancer Research and Drug Discovery

Systems Biology in Cancer Research and Drug Discovery
Author: Asfar S Azmi
Publisher: Springer Science & Business Media
Total Pages: 425
Release: 2012-09-29
Genre: Medical
ISBN: 9400748191

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Systems Biology in Cancer Research and Drug Discovery provides a unique collection of chapters, by world-class researchers, describing the use of integrated systems biology and network modeling in the cancer field where traditional tools have failed to deliver expected promise. This book touches four applications/aspects of systems biology (i) in understanding aberrant signaling in cancer (ii) in identifying biomarkers and prognostic markers especially focused on angiogenesis pathways (iii) in unwinding microRNAs complexity and (iv) in anticancer drug discovery and in clinical trial design. This book reviews the state-of-the-art knowledge and touches upon cutting edge newer and improved applications especially in the area of network modeling. It is aimed at an audience ranging from students, academics, basic researcher and clinicians in cancer research. This book is expected to benefit the field of translational cancer medicine by bridging the gap between basic researchers, computational biologists and clinicians who have one ultimate goal and that is to defeat cancer.


Biochips as Pathways to Drug Discovery

Biochips as Pathways to Drug Discovery
Author: Andrew Carmen
Publisher: CRC Press
Total Pages: 420
Release: 2006-10-19
Genre: Medical
ISBN: 1420015605

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In the fiercely competitive pharmaceutical marketplace, your organization cannot afford to spend excess dollars developing drugs that will fail to get FDA approval or have profoundly poor characteristics. Biochips as Pathways to Drug Discovery takes a comprehensive look at how the industry faces these challenges, using new technologies such as bioc


Beyond Discovery

Beyond Discovery
Author: Director of Commercialization College of Veterinary Medicine Jean E Schelhorn
Publisher: Oxford University Press
Total Pages: 209
Release: 2022-01-14
Genre: Academic-industrial collaboration
ISBN: 0197512712

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"The book is a guide for academic researchers, especially scientists and engineers, on how to move their discoveries to the marketplace. Few academics understand what tech transfer is or how it works, and many shy away from it because they equate commercialization with starting a company. Yet those same individuals can be intrigued to learn of additional pathways that enable discoveries to be translated into marketable products or services. We help researchers explore multiple routes for commercialization, guides them through the personal decisions they must face, describes programs designed to help them, and provides advice to avoid common problems. We frame commercialization as the primary (often the only) way for research to solve societal problems. Impact can best be achieved if, a discovery leads to an invention/ that fills an unmet need in the marketplace. The range of entities that support technology transfer are described, and we offer best practices for researchers to maximize support the process. Engaging researchers effectively requires that institutions themselves adapt. Aligning commercialization with the rewards system is crucial, and integrating commercialization training into graduate and postdoctoral programs will produce the next generation of academic inventors. Furthermore, women and minorities face special challenges that must be overcome so that everyone's discovery receives support for commercialization. Woven through the book are profiles of academic inventors, which illustrate key points and help researchers to visualize themselves in such a role"--


Multiple Pathways to the Student Brain

Multiple Pathways to the Student Brain
Author: Janet Zadina
Publisher: John Wiley & Sons
Total Pages: 295
Release: 2014-06-09
Genre: Education
ISBN: 1118567617

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From an award-winning neuroscience researcher with twenty years of teaching experience, Multiple Pathways to the Student Brain uses educator-friendly language to explain how the brain learns. Steering clear of “neuro-myths,” Dr. Janet Zadina discusses multiple brain pathways for learning and provides practical advice for creating a brain-compatible classroom. While there are an abundance of books and workshops that aim to integrate education and brain science, educators are seldom given concrete, actionable advice that makes a difference in the classroom. Multiple Pathways to the Student Brain bridges that divide by providing examples of strategies for day-to-day instruction aligned with the latest brain science . The book explains not only the sensory/motor pathways that are familiar to most educators (visual, auditory, and kinesthetic), it also explores the lesser known pathways--reward/survival, language, social, emotional, frontal lobe, and memory/attention--and how they can be tapped to energize and enhance instruction. Educators are forever searching for new and improved ways to convey information and inspire curiosity, and research suggests that exploiting different pathways may have a major effect on learning. Multiple Pathways to the Student Brain allows readers to see brain science through the eyes of a teacher—and teaching through the eyes of a brain scientist.


Experimentation in Mathematics

Experimentation in Mathematics
Author: Jonathan M. Borwein
Publisher: CRC Press
Total Pages: 372
Release: 2004-04-12
Genre: Mathematics
ISBN: 1439864195

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New mathematical insights and rigorous results are often gained through extensive experimentation using numerical examples or graphical images and analyzing them. Today computer experiments are an integral part of doing mathematics. This allows for a more systematic approach to conducting and replicating experiments. The authors address the role of